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Find cheap flights from John Wayne (Santa Ana) to Missouri from $41

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santa Ana to Missouri departing on 5/21. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
0 bags
Mon 5/27
Mon 6/3

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Best Missouri Flight Deals

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours

St. Louis
St. Louis1 stop$137
Springfield
Springfield1 stop$246
Columbia
Columbia1 stop$610
Joplin
Joplin1 stop$440

Good to know

Low season

January

High season

April

Cheapest flight

$41
Best time to beat the crowds but there is an average 3% increase in price.
Most popular time to fly and prices are also 16% lower on average.
Flight from Santa Ana to St. Louis

FAQs - booking Missouri flights

  • How does KAYAK find such low prices on flights from John Wayne (Santa Ana) to Missouri?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from John Wayne (Santa Ana) to Missouri.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from John Wayne (Santa Ana) to Missouri?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Missouri from John Wayne (Santa Ana) is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from John Wayne (Santa Ana) to Missouri?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Missouri with an airline and back to John Wayne (Santa Ana) with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from John Wayne (Santa Ana) to Missouri?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Missouri from John Wayne (Santa Ana) up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Top tips for finding cheap flights to Missouri

  • Morning departure is around 3% more expensive than an evening flight, on average*.
*Average of the lowest prices shown in KAYAK’s search results for departures within the next 30 days

Top 5 airlines serving from Santa Ana to Missouri

 
Need help choosing which airline to fly with from Santa Ana to Missouri? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
Alaska AirlinesOverall score based on 9117 reviews
8.2boarding
8.6crew
7.3entertainment
7.3food
7.9comfort
Airline reviews

Alaska Airlines was fantastic. Kayak on the other hand was extremely poor. I got tickets through Kayak for a flight to a funeral. The date got changed less than 12 hours after I made my reservations. When I attempted to change my flights through Kayak, I was unable to use either the website or the phone system. The phone matrix did not give an option to cancel or change. The website said Kayak could not find any record of me making airline reservations through Kayak and even through I never left the Kayak website when making the reservations to my knowledge. After more than a half hour of frustration on the phone and computer ( on top of dealing with the death of a member of my family) I finally contacted Alaska Airline directly and they cancelled my flight and refunded the cost very quickly and efficiently. Alaska Airlines gets 10 stars. Kayak gets zero stars and has permanently lost a customer. I will never use Kayak again.

10.0 ExcellentLarry, Apr 2024SAN - TPA
Read more about Alaska Airlines reviews

Alaska Airlines was fantastic. Kayak on the other hand was extremely poor. I got tickets through Kayak for a flight to a funeral. The date got changed less than 12 hours after I made my reservations. When I attempted to change my flights through Kayak, I was unable to use either the website or the phone system. The phone matrix did not give an option to cancel or change. The website said Kayak could not find any record of me making airline reservations through Kayak and even through I never left the Kayak website when making the reservations to my knowledge. After more than a half hour of frustration on the phone and computer ( on top of dealing with the death of a member of my family) I finally contacted Alaska Airline directly and they cancelled my flight and refunded the cost very quickly and efficiently. Alaska Airlines gets 10 stars. Kayak gets zero stars and has permanently lost a customer. I will never use Kayak again.

The WIFI didn't work well enough to get through even 5 minutes of a movie I had selected (it just kept pausing and spinning), and I just gave up and read a book. The selection of movies was a little sparse though, so reading wasn't that bad of an option. This was an older 737-800, with undersized overhead bins -- but it doesn't make sense to me that we are told to slide our bags in with the wheels facing us (most people ignore that and put the handles facing us). This makes it more difficult to remove the bags (no handle). The flight went well, and the fruit/cheese platter I pre-ordered was good -- although it is a little annoying to have to pre-order for this (but I suppose it saves time). When I pre-order it automatically gets charged to my personal credit card (Alaska VISA), when I'd prefer to use my corporate card for that on business trips.

Good - San Jose security is a breeze. Exact opposite of San Diego. Flight on time. Bad - FA's were not that cheery or polite. I thought we may blow out a tire as the pilot slammed down a hard landing in perfect conditions. He came in pretty hot like he had a date waiting.

It was our baby’s first flight and everything went perfect. The flight attendant gave him his first set of wings and we were smooth flying from there.

The messaging about the change in flight destination and options for getting to SFO was poor. There should have been frequent updates. When I spoke to the boarding agent moment before we were supposed to board, he was flippant and offered no help before the announcement was made that transportation would be arranged. It was as poor of an experience that I've ever had.

My plane ride down landed 20 min late. Boarding at SFO was strange too. The people at the terminal were nice—but, boarding lacked direction, and was confusing . Coming back was worse—the plane was hours behind—and I barely caught the last Bart train back to San Francisco (3 min more and I would have been in trouble). It was a very stressful trip, and it didn’t need to be.

This leg was better than the previous leg mostly because I upgraded my searing and the crew was nicer

I like that we took off on time and arrived a bit early. I like that I could gate check my bag and board early. I don't like how crowded the flight was. I had ok leg room, but could feel every move of the person next to me. And the aisles are very narrow. The gate and flight crews were terrific.

I appreciated the ability to choose between multiple flights both into and out of Portland from Burbank on the same day, so we were able to attend an event and return without spending the night. I am unable to appreciate what Alaska Air calls "streamlining" the checkin/boarding process at Burbank Airport. If you have a smartphone and the Alaska Air app, it is probably fine, but removing the option of using onsite kiosks to print boarding passes does not meet my definition of "streamlined". I also found it challenging that both Portland and Burbank airports required the plane to sit on the runway for some time due to lack of an open gate at which to disembark. It would not be so bad if we could at least remove our seat belts and move a little bit while we waited, but that is not an option. I honestly don't know whether this is because of how Alaska Air operates, or just the circumstances of the particular day and airports we were using, but I normally do not experience these kinds of delays to reach a gate using Southwest Air.

This flight was significantly affected by poor wifi connections. I couldn’t get my work done because the wifi kept dropping. Even texts were not going through. There is no seat power in premium class either. I fly a lot. Today was my 10th flight in 4 weeks. This was by far the only flight that was sub par.

There was a loud squeaky sound the whole time we were flying.

On 2 different flights the wifi was horrible and there was no drink or snack service.

I didn’t not like that I could not select my seat and ended up with the worse seat.

The landing was bad and the hostess came two times and i was sleeping but when she served the person that nexts to me I woke up and she didn’t even asked me if I need any drink or snacks two times!!!!

Plane was late because of a mechanical malfunction and the food listed as available was not. Flight attendants seem over worked and under paid. They just done seem happy. And that can be seen in their faces.

Waited 3 hours on a plane to de-ice due to manpower issues. Waited another hour and a half once we landed because of a gate issue. Missed my connections. Created. A total of 13 hours of delay.

There was no FREE wi-fi nor entertainment screens at all.

Great, on time departure, friendly and accommodating crew, great leg room, Smith flight

Plane was turned around due to fog half way into the flight, Delta did not properly direct passengers to stay on same flight and instead failed to properly rebook on Alaska

Like most domestic flights in the US, you are basically on your own with this airline when it comes to food, so be sure to purchase meals and drinks ahead of time or expect to arrive starving and dehydrated (like I was).

Last minute gate change nearly caused us to miss our flight. Change was not announced or displayed in the main board at the old gate. Terrible communication. When we landed we had to wait 20 minutes because there was another plane at the assigned gate. Not the crew’s fault, but adding 20 minutes to a 45 minute flight sucked.

Due to one crew member not showing up to work, our flight was significantly delayed causing us to miss our connecting flight in Houston to Mississippi causing us to be delayed by more than 6 hours and missing our event all together. Very disappointing. All because ONE crew member called in sick. United did grant us a $15 meal voucher, which was a small but appreciated concession that I wasn’t able to use because I ordered my lunch and paid for it before applying the concession, and the staff said it was too late to use it. Ugh! We also had a TWO delay coming back from Mississippi, but that was on American Airlines and it was due to weather, so not their fault. Anyway, not at all impressed with United’s handling of our flight and the HUGE disappointment of missing our important family event for our 90 year old mother. All that money and all that stress and emotions for nothing. Having to wait the hour to bring an employee from LAX seemed like something that should not have happened. Why don’t you have a local back-up? Santa Ana is not a little airport in a rural area.

Crew was great and did their best to make us comfortable and captain came out at the beginning to announce why the flight was delayed, weather situation up ahead, and kept us updated throughout the flight.

United WiFi is consistently unusable (it can take 10 mins to load a single web page). If you need Wifi to do work, be prepared to lose half a day of productivity.

Awful. I got stuck next to a person carrying a dog and behind someone with a dog. People need to board these dogs downstairs. The cabin is crowded enough with your pets

Packed in like sardines, very uncomfortable. Sitting the aisle my shoulder was rammed into numerous times by rushing flight attendants. Also flight was very cold.

the head jack on my seat didn't work and the power outlet didn't work for my seat

Left 2 hours later for delayed I had to take care a kid with special need since people don’t want to move to accommodate the rest of the family. . It wasn’t bad but that made me upset that people can be that selfish.

For a 22 minute flight all you expect is for it to be safe and comfortable

Flight was on time. Staff were friendly. I paid for Economy Plus but was required to check my standard carry-on luggage due to lack of space on the aircraft. This cost me 30 minutes, unexpectedly, in waiting at the baggage claim. This experience did not meet my expectations.

The experience was great and much better than the flight going out. of course I was in first class but the service was excellent

Comfort of seats, ease of boarding. Food selection could be better

Food options were limited which is absolutely embarrassing for a Flight of this size The staff did not come around as much and I am not accustomed to such poor service from American Airlines Drinks I believe were limited to soda and water

Crew were attentive and friendly. Flight was smooth and early! I enjoyed the less crowded plane. Thank you!

We are gluten free, there were not any available complimentary gluten free options.

Flight delayed, boarding time kept changing, not good. Nee firm information given each time.

No meal on a cross country flight? SFO-MiA is pretty much the definition of a coast to coast flight. No meal provided. Sky high wi-fi rates too. Stop nickel and diming your customers.

The staff was unprofessional and didn’t communicate very well. The boarding process was very disheveled, potentially due to a power outage the previous day but there was no contingency plan to properly get passengers boarded the following day. Once boarded the aircraft stayed on the tarmac for over 45 minutes due to high winds. The communication was sporadic but an announcement was finally made an additional 30 minutes later that the flight was cancelled but we couldn’t get off the plane. Prior to deplaning one of the gate agents came on the plane and made an announcement for everyone to pickup their checked bags and take a card to rebook a new reservation because they didn’t have adequate staff. Flights were missed, passengers went to different airports and there was little to no assistance from AA.

Apart from the delay due to unforeseen circumstances. The leg from sjc to dfw was fine. It was the leg from dfw to orf that we encountered issues mainly due to the flight attendant crew not being friendly. We had two small children and we needed some assistance to warm up milk so the baby would sleep. The crew just didn’t get it and made things very difficult. One made a remark that the baby’s dirty diaper smell was a “gift” to the plane in a rude way. Normally I’d brush that off as a funny comment if the rest of the trip the attendants were helpful or understanding of the difficulty we faced. But that wasn’t the case. We were met with rudeness on the second leg. Whereas on the first leg the crew were so nice and helpful.

Flight From PHX to CVG was on time, very professional staff

what I like about Spirit is that the pilot and crew are good communicators. The plane itself - well, its a budget airline and you get what is expected, But I generally just feel safer, somehow, when I know more about what is going on - and Spirit has always done a good job of telling me what is going on: why the delay, why the turbulence, why this and that... and that means a lot to me.

I paid just under 200 for flight and luggage, then paid 200 to change the flight, then paid 100 for a carry on. Then the cancelled the flight. Of the 500 I spent they refunded 250. I bought a delta flight for 270 never flew with spirit, but spirit kept 250, not even refunding the 100 for the carry on though they cancelled the flight (for weather on a day with only a slight rain ).

Flight was canceled. Knew there was weather, and were notified of 20 min delayed, and then suddenly canceled. Next reschedule was for 2 days. No help other than to refund. Thankfully full refund and appreciate that. I appreciate discounted airline but felt they could've done more for customer inconvenience.

Flying on Spirit Airline is a penny-pinching beat down.

Kayak does not know that spirit airlines charged me $70 to fly. But the bag check-in was $89 each way. This is false advertising to lure people. Spirit airlines sends bunch of emails after flight purchases to buy wifi, better seats, priority boarding, secure reserved seats. This is false advertising. Up front pricing. I would of flown jet blue or Alaska airlines.

One hour late taking off. Concerning, very hard landing. Uncomfortable seats with no recline. Extremely slow baggage claim. Very professional, knowledgeable flight attendants. Brand new, very clean plane.

Can’t say there was anything I particularly liked. Seats were very tight, leather wrapped plastic. I followed up a much longer and cheaper trip from Honolulu on southwest, everything was phenomenal, this flight was the exact opposite. Blows my mind they charge for water of all things. One of the attendants seemed very rude, I watched a taller gentleman a couple rows forward with his knees pressed into the back of the seat ahead, while the woman in that seat leaned forward the entire flight, I’m sure because she could feel his knees. I’ll be avoiding spirit like the plague from here forward.

Didn’t make the connecting flight due to a delay on our first flight.

I felt scam to have to pay $50 additional for my carry on luggage which was free for my other airline.

Enjoyed the experience, on time flights, friendly staff the WiFi was intros d kept cutting out.

Book cheap flights from John Wayne (Santa Ana) to Missouri

Recent round-trip flight deals

5/22Wed
1 stopFrontier
10h 36mSNA-MCI
5/28Tue
1 stopFrontier
25h 05mMCI-SNA
$137
5/23Thu
1 stopFrontier
15h 44mSNA-STL
5/28Tue
1 stopFrontier
22h 05mSTL-SNA
$137
9/17Tue
1 stopAmerican Airlines
5h 17mSNA-SGF
9/24Tue
1 stopAmerican Airlines
5h 20mSGF-SNA
$246
9/1Sun
1 stopDelta
7h 30mSNA-SGF
9/24Tue
1 stopDelta
9h 18mSGF-SNA
$287
5/31Fri
1 stopAmerican Airlines
7h 14mSNA-SGF
6/5Wed
1 stopAmerican Airlines
5h 34mSGF-SNA
$306
5/31Fri
1 stopDelta
8h 09mSNA-SGF
6/5Wed
2 stopsDelta
12h 05mSGF-SNA
$323
5/29Wed
1 stopUnited Airlines
5h 24mSNA-MCI
5/31Fri
1 stopUnited Airlines
4h 56mMCI-SNA
$358
5/30Thu
1 stopUnited Airlines
5h 24mSNA-MCI
6/1Sat
1 stopUnited Airlines
8h 15mMCI-SNA
$408
10/10Thu
1 stopAlaska Airlines
7h 07mSNA-MCI
10/17Thu
1 stopAlaska Airlines
9h 25mMCI-SNA
$436
5/22Wed
1 stopAlaska Airlines
9h 56mSNA-STL
5/25Sat
1 stopAlaska Airlines
9h 56mSTL-SNA
$580

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Recent one-way flight deals

5/21Tue
1 stopSpirit Airlines
26h 01mSNA-STL
$41
5/7Tue
1 stopSpirit Airlines
12h 33mSNA-MCI
$59
7/8Mon
1 stopDelta
9h 44mSNA-MCI
$178
7/13Sat
1 stopUnited Airlines
6h 29mSNA-MCI
$198
5/21Tue
2 stopsAmerican Airlines
7h 33mSNA-STL
$224
6/8Sat
1 stopAlaska Airlines
15h 14mSNA-STL
$227
7/12Fri
1 stopUnited Airlines
5h 25mSNA-MCI
$239
7/7Sun
1 stopDelta
8h 14mSNA-MCI
$258
7/10Wed
2 stopsAmerican Airlines
8h 23mSNA-MCI
$273
6/8Sat
2 stopsAlaska Airlines
12h 15mSNA-STL
$303

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Last minute flights from Santa Ana to Missouri

Last minute flight, train and bus deals

4/30Tue
multi-stop
25h 58mSNA-STL
5/5Sun
multi-stop
19h 10mSTL-SNA
$376
4/30Tue
multi-stopSpirit Airlines
25h 58mSNA-STL
5/5Sun
multi-stopSpirit Airlines
29h 51mSTL-SNA
$428
5/2Thu
multi-stopSpirit Airlines
21h 23mSNA-MCI
5/6Mon
multi-stopSpirit Airlines
4h 51mMCI-SNA
$498
5/2Thu
multi-stopSpirit Airlines
21h 23mSNA-MCI
5/6Mon
multi-stopSpirit Airlines
20h 05mMCI-SNA
$542
4/30Tue
multi-stop
26h 43mSNA-STL
5/5Sun
multi-stop
29h 51mSTL-SNA
$601
4/30Tue
multi-stopUnited Airlines
5h 48mSNA-STL
5/1Wed
multi-stopUnited Airlines
5h 43mSTL-SNA
$766
4/30Tue
multi-stopUnited Airlines
12h 49mSNA-STL
5/5Sun
multi-stopUnited Airlines
7h 54mSTL-SNA
$771
5/1Wed
multi-stopAlaska Airlines
11h 45mSNA-MCI
5/4Sat
multi-stopAlaska Airlines
9h 48mMCI-SNA
$1,009
4/30Tue
multi-stopAlaska Airlines
10h 24mSNA-STL
5/1Wed
multi-stopAlaska Airlines
8h 45mSTL-SNA
$1,301
5/2Thu
multi-stopDelta
11h 56mSNA-MCI
5/6Mon
multi-stopDelta
12h 03mMCI-SNA
$1,597

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Santa Ana - Missouri Flights

Departure:

John Wayne (Santa Ana) (SNA)United States

Return flight deals:

Missouri - John Wayne (Santa Ana)

Cabin classes: