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MYR - DSM

$135 Find cheap flights from Myrtle Beach to Des Moines

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to Des Moines departing on 6/12. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
0 bags
Sat 6/15
Sat 6/22

Search hundreds of travel sites at once for deals on flights to Des Moines

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to Des Moines, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to Des Moines, as well as popular online travel agencies
In the last 7 days travelers have searched 42,393,389 times on KAYAK, and here is why:

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Cheap flight deals from Myrtle Beach to Des Moines (MYR-DSM)

 
These are the cheapest deals for flights from Myrtle Beach to Des Moines currently on KAYAK along with options from the most popular airlines KAYAK users selected for this route. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.

Recent round-trip flight deals from Myrtle Beach to Des Moines

Recommended round-trip deals departing in the coming months from the most popular airlines that fly from Myrtle Beach to Des Moines.

Recent one-way flight deals from Myrtle Beach to Des Moines

Only flying one-way? Below are some of the best one-way flight deals from Myrtle Beach to Des Moines found on KAYAK recently.

Recent last minute flight deals from Myrtle Beach to Des Moines

Leaving soon but still want a bargain? Check out these latest deals for last minute flights from Myrtle Beach to Des Moines.

Recent direct flight deals from Myrtle Beach to Des Moines

The latest deals for direct flights from Myrtle Beach to Des Moines so you can sit back and relax without the need for a layover.

Cheap bus & train deals from Myrtle Beach to Des Moines

Find recent round-trip train or bus tickets from Myrtle Beach to Des Moines.

All round-trip flight deals to Des Moines

The cheapest plane tickets to Des Moines found on KAYAK recently.
Discover the best prices and deals for you by selecting your travel dates.
Choose your dates
1:07 pm - 7:04 pmMYR-DSM
6h 57m1 stop
1:50 pm - 10:54 pmDSM-MYR
8h 04m1 stop
$250Delta
Find Deal
Thu, May 30 - Mon, Jun 3
7:32 pm - 10:47 amMYR-DSM
16h 15m1 stop
9:00 am - 9:43 pmDSM-MYR
11h 43m2 stops
Thu, May 23 - Thu, May 30
11:37 am - 4:29 pmMYR-DSM
5h 52m1 stop
6:14 pm - 11:13 pmDSM-MYR
3h 59m1 stop
$320Delta
Find Deal
Thu, May 23 - Thu, May 30
7:32 pm - 10:47 amMYR-DSM
16h 15m1 stop
9:00 am - 7:20 pmDSM-MYR
33h 20m3 stops
Thu, May 23 - Thu, May 30
1:07 pm - 7:04 pmMYR-DSM
6h 57m1 stop
6:14 pm - 11:13 pmDSM-MYR
3h 59m1 stop
$336Delta
Find Deal
Thu, May 30 - Mon, Jun 3
10:29 am - 10:47 amMYR-DSM
25h 18m3 stops
9:00 am - 9:43 pmDSM-MYR
11h 43m2 stops
Thu, May 23 - Thu, May 30
7:46 pm - 10:56 pmMYR-DSM
4h 10m1 stop
3:07 pm - 10:02 pmDSM-MYR
5h 55m1 stop
$445American Airlines
Find Deal
Thu, Aug 8 - Sun, Aug 11
7:46 pm - 10:56 pmMYR-DSM
4h 10m1 stop
6:00 am - 2:16 pmDSM-MYR
7h 16m2 stops
$480American Airlines
Find Deal
Thu, Aug 8 - Sun, Aug 11
3:01 pm - 9:54 pmMYR-DSM
7h 53m2 stops
6:00 am - 2:16 pmDSM-MYR
7h 16m2 stops
$590American Airlines
Find Deal
Thu, Aug 8 - Sun, Aug 11
2:52 pm - 11:02 pmMYR-DSM
9h 10m2 stops
12:32 pm - 10:14 pmDSM-MYR
8h 42m2 stops
$593American Airlines
Find Deal
Thu, May 30 - Mon, Jun 3
7:03 am - 1:41 pmMYR-DSM
7h 38m1 stop
$135Delta
Find Deal
Wed, Jun 12
12:44 pm - 1:05 pmMYR-DSM
25h 21m3 stops
Wed, Jun 12
7:46 pm - 12:05 amMYR-DSM
5h 19m1 stop
$142American Airlines
Find Deal
Wed, Jun 26
11:22 am - 7:07 pmMYR-DSM
8h 45m2 stops
$173American Airlines
Find Deal
Wed, Jun 12
2:32 pm - 5:19 pmMYR-DSM
27h 47m3 stops
Wed, Jun 26
9:40 pm - 5:19 pmMYR-DSM
20h 39m2 stops
Wed, Jun 26

Flights from Myrtle Beach to Des Moines - Travel Insights & Trends

Get data-powered insights and trends into flights from Myrtle Beach to Des Moines to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Myrtle Beach to Des Moines?

The average price of all flights from Myrtle Beach to Des Moines clicked on KAYAK for each day over the last 12 months.
If you are looking for a flight deal from Myrtle Beach to Des Moines, look for departures on Mondays and avoid leaving on a Friday, as it's usually the priciest day. When flying back from Des Moines, Tuesday is the cheapest day to fly and Monday is the most expensive.

Which airlines provide the cheapest flights from Myrtle Beach to Des Moines?

The cheapest price for the route for each airline clicked by KAYAK users in the last 72 hours.
In the last 3 days, Delta offered the best one-way deal for that route, at $135. KAYAK users also found Myrtle Beach to Des Moines round-trip flights on Delta from $250 and on American Airlines from $445.

Good to know

Low season

February

High season

October

Cheapest flight

$135
Best time to beat the crowds with an average 36% drop in price.
Most popular time to fly and prices are also 4% lower on average.
Flight from Myrtle Beach to Des Moines

When to book flights from Myrtle Beach to Des Moines

Are your dates flexible? Find out the best times to travel from Myrtle Beach to Des Moines based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Myrtle Beach to Des Moines

  • What is the cheapest flight from Myrtle Beach to Des Moines?

    In the last 3 days, the lowest price for a flight from Myrtle Beach to Des Moines was $135 for a one-way ticket and $250 for a round-trip.

  • Do I need a passport to fly between Myrtle Beach and Des Moines?

    A passport is not required to fly from Myrtle Beach to Des Moines.

  • Which airports will I be using when flying from Myrtle Beach to Des Moines?

    When flying out of Myrtle Beach you will be using Myrtle Beach Intl. You will be landing at Des Moines, also known as Des Moines.

  • Which aircraft models fly most regularly from Myrtle Beach to Des Moines?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Myrtle Beach to Des Moines?

    SkyTeam, and oneworld are the airline alliances operating flights between Myrtle Beach and Des Moines, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Myrtle Beach to Des Moines, Delta or American Airlines?

    The two airlines most popular with KAYAK users for flights from Myrtle Beach to Des Moines are Delta and American Airlines. With an average price for the route of $386 and an overall rating of 8.0, Delta is the most popular choice. American Airlines is also a great choice for the route, with an average price of $306 and an overall rating of 7.3.

  • How does KAYAK find such low prices on flights from Myrtle Beach to Des Moines?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to Des Moines.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to Des Moines?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Des Moines from Myrtle Beach is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to Des Moines?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Des Moines with an airline and back to Myrtle Beach with another airline. Booking your flights between Myrtle Beach and DSM can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to Des Moines?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Des Moines from Myrtle Beach up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Top airlines flying from Myrtle Beach to Des Moines

 
See real verified KAYAK customer reviews for airlines flying from Myrtle Beach to Des Moines. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Myrtle Beach to Des Moines? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 10673 reviews
8.6Crew
7.4Food
7.9Comfort
8.0Entertainment
8.2Boarding
Airline reviews

A regional sized plane was used for a cross country flight with no overhead bin space. I had to "pink check" my laptop and my medications. I was NOT pleased!!!!

4.0 OkayReginald, May 2024MCI - LGA
Read more about Delta reviews

A regional sized plane was used for a cross country flight with no overhead bin space. I had to "pink check" my laptop and my medications. I was NOT pleased!!!!

Absolutely nothing flight was cancelled and delayed for 2 days. Barely a heads up I want a full refund

The plane from SNA wouldn’t start after 5 tries. The team gave me an option of flying direct from LAX and giving me a Lyft ride there! Perfect!

Best airline! Always friendly and welcoming. Skyclub was great and loved the fast free wifi on board. I also love that you can pre-order your meal on the app!

Atlanta boarding crew at gate were filled with arrogance and were disrespectful. In flight crew showed indifference to the needs of passengers. This is about the flight from ATL to BDL.

Boarding was somewhat chaotic. Unable to evaluate crew or food/drink because captain kept them seated due to turbulence. Have no idea if entertainment was offered.

The gate area was incredibly short staffed, with one representative manning 4-5 flights, which caused a 3 hr delay in boarding even though the plane was all ready to leave. Other flights also were delayed because of this. The flight crew was awesome and I feel bad for the only gate worker on call, but Delta needs to hire more employees.

Very frustrated with boarding gate crew. She announced the plane was small and they would be limiting us to one item to carry on. Not a problem for me as I understand the tiny planes have limited space!! Not the case here! It was a rather large plane and had plenty of room for bags! So because I don’t want to be one of “those people” who ignores the request to check a carry on I did so asking if I would be able to pick it up at the bottom of the ramp on arrival in Knoxville to which she responded “yes”! Then I watched as every other passenger held onto their 2 items and boarded!! Then when we arrived in Knoxville our 2 carry ons had been put with all the other luggage and we had to go to baggage pick up and wait for all the big checked bags to come off the carousel! So she lied!! Frustrating. Next time I won’t be so nice!

It was a good experience except when boarding a female flight attendant did not go out of her way to assist my teenage daughters in finding space for their carry-ons after their compartments were full.

On time departure, smooth trip, flight attendant told through passengers the gate we would arrive at and the gate our outbound flight was departing from. Early arrival

Tray table was filthy when I sat down. I needed to have someone come clean it because there was food and stains on it WiFi didn’t work after paying for in-flight WiFi. Food was terrible and was not filling at all Chicken was rubbery Flight attendant had an attitude, interrupted me and wasn’t able to answer basic questions about the food selection such as “does the chicken have red sauce in it”. If your flight attendants are not going to know what is in the meals so we can make an educated decision based on dietary restrictions, they shouldn’t be on the plane. My 1.5 year old niece was sleeping and dropped her binkie. I went on the ground under the chairs looking for it. It was at that time that she came up to me as I’m CLEARLY on all 4s with a flashlight and said “I need to get by”. I said one moment please I’m getting something from under the seat (while my head was literally under the seat). Her reply was “no you need to move now” and proceeded to almost push me out of the way. I looked up and all I saw was her toes under my eyes. When I looked in front of me, her private parts were inches away from my face. I then made a comment “you couldn’t waited 2 seconds?” and her response was, “no I need to use the bathroom”. I understand that and would never want to be the reason someone couldn’t get to the bathroom but I was under the seat. She could’ve gone around the other way instead of harassing me, basically placing her private parts on my head and borderline pushing me out of the way. You don’t pay that much for this deplorable experience. This was by far the worst experience I have ever had on American. I will be absolutely thinking twice and thrice about flying American Airlines again. I would rather pay more to fly delta because at least I know their WiFi will work and their flight attendants won’t have a shitty attitude for no reason, nor will they act the way this woman did. Unacceptable.

Liked - nothing. Disliked - delayed 35+ min sitting on the plane. Caused me to miss my connection in Charlotte. American Airlines is the worst US Air Carrier company with atrocious customer service.

Worst situation ever! I booked my tickets for this trip on Alaska Airlines. I guess AA is a partner and we flew nonstop from Eugene to PHX on an AA jet. I had to pay for luggage from PHX to EUG. And this was an Alaska Airlines reservation paid for with Alaska airlines credit card! Got to the PHX airport and was not able to check bags because of some weird issue with the AA software. My reservation had to be the-entered by the agent. I will never pick another American Airlines flight on the Alaska Airlines website. While on vacation, I tried to upgrade our seats for the trip home. The request just buffered and never went through. I tried four times and was charged four times on my credit card. The card was charged but the seats were never changed. What a wreck!

Left from gate 30 minutes before flight. Never been late to a flight ever. It says 15 minutes before explicitly on the ticket.

I like the boarding process, it was fast. The seat doesn’t have a TV for a long flight and food wasn’t served, just snacks.

Use planes with TVs on flights over 4 hours. The free entertainment was a cheap in between solution for a very long flight that you don't even bother providing meals or decent snacks.

Even though we left CMI late, we mostly made up the time.

Delayed almost 4 hours for a 45 minute flight with no explanation.

Again, multiple delays and I eventually just canceled and drove!

Great crew. We were delayed so that late passengers could get on the flight. Love the bedding in business class. Good food. Great experience.

Book cheap flights from Myrtle Beach to Des Moines

Recent one-way flight deals

 
Only flying one-way? Below are some of the best one-way flight deals from Myrtle Beach to Des Moines found on KAYAK in the last 72 hours.
6/12Wed
1 stopDelta
7h 38mMYR-DSM
$135
6/12Wed
3 stops
25h 21mMYR-DSM
$141
6/26Wed
1 stopAmerican Airlines
5h 19mMYR-DSM
$142
6/12Wed
2 stopsAmerican Airlines
8h 45mMYR-DSM
$173
6/26Wed
3 stops
27h 47mMYR-DSM
$182
6/26Wed
2 stops
20h 39mMYR-DSM
$195

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Myrtle Beach - Des Moines Flights

Departure:

Myrtle Beach (undefined)United States

Destination:

Des Moines (DSM)United States

Return flight deals:

Des Moines - Myrtle Beach

Cabin classes: