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MYR - DSM

$292 Find cheap flights from Myrtle Beach to Des Moines

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to Des Moines departing on 7/30. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
0 bags
Sat 6/1
Sat 6/8

Search hundreds of travel sites at once for deals on flights to Des Moines

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to Des Moines, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to Des Moines, as well as popular online travel agencies
In the last 7 days travelers have searched 43,740,974 times on KAYAK, and here is why:

Save 22% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Bundle and saveSave money when you bundle your flight + hotel.

Cheap flight deals from Myrtle Beach to Des Moines (MYR-DSM)

Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to Des Moines that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices and deals for you by selecting your travel dates.
Choose your dates
8:09 pm - 11:37 pmMYR-DSM
4h 28m1 stop
4:02 pm - 10:23 pmDSM-MYR
5h 21m1 stop
$292American Airlines
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Tue, Jul 30 - Fri, Aug 2
7:46 pm - 10:56 pmMYR-DSM
4h 10m1 stop
3:07 pm - 10:02 pmDSM-MYR
5h 55m1 stop
$307American Airlines
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Thu, Aug 8 - Sun, Aug 11
12:40 pm - 7:45 pmMYR-DSM
8h 05m2 stops
4:02 pm - 10:23 pmDSM-MYR
5h 21m1 stop
$394American Airlines
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Tue, Jul 30 - Fri, Aug 2
7:46 pm - 12:05 amMYR-DSM
5h 19m1 stop
4:02 pm - 11:49 pmDSM-MYR
6h 47m1 stop
$413American Airlines
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Fri, Jun 14 - Sun, Jun 16
9:10 am - 2:33 pmMYR-DSM
6h 23m2 stops
3:07 pm - 10:02 pmDSM-MYR
5h 55m1 stop
$475American Airlines
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Thu, Aug 8 - Sun, Aug 11
5:03 am - 11:37 amMYR-DSM
7h 34m2 stops
6:49 am - 6:01 pmDSM-MYR
10h 12m2 stops
$573American Airlines
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Tue, Jul 30 - Fri, Aug 2
6:43 am - 2:33 pmMYR-DSM
8h 50m2 stops
6:00 am - 2:16 pmDSM-MYR
7h 16m2 stops
$575American Airlines
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Thu, Aug 8 - Sun, Aug 11
7:46 pm - 12:05 amMYR-DSM
5h 19m1 stop
6:52 am - 6:58 pmDSM-MYR
11h 06m2 stops
$628American Airlines
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Fri, Jun 14 - Sun, Jun 16
9:07 am - 8:02 pmMYR-DSM
11h 55m2 stops
6:52 am - 6:58 pmDSM-MYR
11h 06m2 stops
$693American Airlines
Find Deal
Fri, Jun 14 - Sun, Jun 16

Flights from Myrtle Beach to Des Moines - Travel Insights & Trends

Get data-powered insights and trends into flights from Myrtle Beach to Des Moines to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Myrtle Beach to Des Moines?

The average price of all flights from Myrtle Beach to Des Moines clicked on KAYAK for each day over the last 12 months.
If you are looking for a flight deal from Myrtle Beach to Des Moines, look for departures on Mondays and avoid leaving on a Friday, as it's usually the priciest day. When flying back from Des Moines, Tuesday is the cheapest day to fly and Monday is the most expensive.

Good to know

Low season

September

High season

December

Cheapest flight

$292
Best time to beat the crowds with an average 31% drop in price.
Most popular time to fly with an average 34% increase in price.
Flight from Myrtle Beach to Des Moines

When to book flights from Myrtle Beach to Des Moines

Are your dates flexible? Find out the best times to travel from Myrtle Beach to Des Moines based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Myrtle Beach to Des Moines

  • What is the cheapest flight from Myrtle Beach to Des Moines?

    In the last 3 days, the lowest price for a flight from Myrtle Beach to Des Moines was $292 for a round-trip ticket.

  • Do I need a passport to fly between Myrtle Beach and Des Moines?

    A passport is not required to fly from Myrtle Beach to Des Moines.

  • Which airports will I be using when flying from Myrtle Beach to Des Moines?

    When flying out of Myrtle Beach you will be using Myrtle Beach Intl. You will be landing at Des Moines, also known as Des Moines.

  • Which aircraft models fly most regularly from Myrtle Beach to Des Moines?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Myrtle Beach to Des Moines?

    oneworld is the only airline alliance operating flights between Myrtle Beach and Des Moines.

  • How does KAYAK find such low prices on flights from Myrtle Beach to Des Moines?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to Des Moines.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to Des Moines?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Des Moines from Myrtle Beach is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to Des Moines?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Des Moines with an airline and back to Myrtle Beach with another airline. Booking your flights between Myrtle Beach and DSM can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to Des Moines?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Des Moines from Myrtle Beach up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Top airlines flying from Myrtle Beach to Des Moines

 
See real verified KAYAK customer reviews for airlines flying from Myrtle Beach to Des Moines. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Myrtle Beach to Des Moines? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 10874 reviews
7.4Food
8.0Entertainment
7.9Comfort
8.2Boarding
8.6Crew
Airline reviews

Delayed due to an ill passenger after loading. Not preventable on Delta's part. Was in first class. The seats are becoming worn and detaching from their velcro attachments. Only got snacks on flight. The attendant was not the friendliest.

6.0 GoodJames, Apr 2024TPA - RDU
Read more about Delta reviews

Delayed due to an ill passenger after loading. Not preventable on Delta's part. Was in first class. The seats are becoming worn and detaching from their velcro attachments. Only got snacks on flight. The attendant was not the friendliest.

I would fly again the whole experience was great. The only feed back I can give that they don't do that American Airlines does is the crew there is more humorous with boarding and thank their passengers. It makes it more fun to fly with them. I would however fly Delta again.

From Atlanta to Cabo I would have hoped on a plane that size I would have been able to breathe and wiggle my feet a little! The leg room in that plane is non existent and I am only 5”4’. And the air vent either wasn’t working very well or just could not blow air from the ceiling to the seat area as I was suffocating through the entire flight! And please don’t say I would have been more comfortable in first class because I cannot afford those rates and have always travelled Main Cabin without issues !

The pilots were good. Disappointing when planes don't have electrical ports

I liked the piloting of the aircraft. Very disappointed about lack of electrical ports. Also, although a short flight. there was enough time to hand out snacks to comfort + seats as was done for first class.

I had a wonderful experience flying with delta. The gentleman taking care of us on our flight was so nice, accommodating, and attentive. He always was smiling and giving pins to the kids which made me smile. The flight was quick too and without turbulence. Thank you for the great flying experience.

Delta is one of the best airlines I have flown

Made the Atlanta to Pittsburgh trip many times, with Delta no issues

I always fly with Delta. My friends tell me their horror stories of flying with other airlines. I just smile and say, “You should fly Delta”

I'm a larger, athletic guy (6'2", 260lbs powerlifter) and I found the seats incredibly uncomfortable with minimal leg room, especially in a window seat. Now, I full understand that being smaller may change my view but even if I was 80lbs less, my legs would be the same size and I was sandwiched between my seat and the seat in front of me.

They gave my seat away although it was a connecting flight with them and the flight was a bit delayed.

Flight was cancelled had to move to another gate late again no internet paid for the month and never can use it waste of money

Not being able to purchase my check in baggage online was a negative.

LATE LATE LATE!!! Plagued by late AA flights on this trip. Such a drag. This one was by far the worst.

WiFi connected but only let you go to the AA website, not even text messaging worked.

Too bad that first class seats do not recline significantly causing discomfort

Flight delayed over an over all day until it cancelled at 1:30am. Would not repeatedly delay that late. Offer hotel rooms and rebook early. Very difficult for families with small children

this is starting to seem like an american airlines standard. delayed flights and fake apologies… getting tired of it

This flight is frequently delayed. The connections seemingly are more frequently delayed. I’ve missed connections as a result twice on the same route to charlotte then Charleston. Final destination arrival has been the next day, twice in a row. No pilots, no crew. Too many excuses. Unfortunately, my days with American are over.

Entertainment was okay not because anything was wrong but it is a short flight so having no wifi is annoying but understandable. Crew was outstanding as usual

Last minute flights from Myrtle Beach to Des Moines

Last minute flight, train and bus deals

 
These last-minute flight deals are the cheapest flights found on KAYAK in the last 72 hours for flights from Myrtle Beach to Des Moines that are departing in the next 10 days.
5/3Fri
multi-stopDelta
23h 37mMYR-DSM
5/6Mon
multi-stopDelta
20h 35mDSM-MYR
$725
5/3Fri
multi-stopDelta
22h 46mMYR-DSM
5/6Mon
multi-stopDelta
20h 35mDSM-MYR
$730
5/3Fri
multi-stopDelta
18h 58mMYR-DSM
5/6Mon
multi-stopDelta
17h 02mDSM-MYR
$735
5/3Fri
multi-stopDelta
23h 37mMYR-DSM
5/6Mon
multi-stopDelta
20h 35mDSM-MYR
$765
5/3Fri
multi-stopDelta
18h 58mMYR-DSM
5/6Mon
multi-stopDelta
20h 35mDSM-MYR
$770
5/3Fri
multi-stopUnited Airlines
10h 52mMYR-DSM
5/6Mon
multi-stopUnited Airlines
7h 52mDSM-MYR
$836

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Myrtle Beach - Des Moines Flights

Departure:

Myrtle Beach (MYR)United States

Destination:

Des Moines (DSM)United States

Return flight deals:

Des Moines - Myrtle Beach

Cabin classes: