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Find cheap flights from South Carolina to Panama City from $124

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to Panama City departing on 6/4. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
0 bags
Sat 6/1
Sat 6/8

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In the last 7 days travelers have searched 43,740,974 times on KAYAK, and here is why:

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Good to know

Low season

September

High season

December

Cheapest flight

$124
Best time to beat the crowds with an average 19% drop in price.
Most popular time to fly with an average 50% increase in price.
Flight from Charleston to Panama City

FAQs for booking flights from South Carolina to Panama City

  • How does KAYAK find such low prices on flights from South Carolina to Panama City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from South Carolina to Panama City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from South Carolina to Panama City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Panama City from South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from South Carolina to Panama City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Panama City with an airline and back to South Carolina with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from South Carolina to Panama City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Panama City from South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Prefer to fly non-stop from South Carolina to Panama City?

Find which airlines fly direct from South Carolina to Tocumen Intl, which days they fly and book direct flights.

Nonstop departures

South Carolina to Panama City Tocumen Intl

Monday

Air Europa, Air France, American Airlines, +19 more

Air Europa, Air France, +20 more

Tuesday

Air Europa, Air France, American Airlines, +16 more

Air Europa, Air France, +17 more

Wednesday

Air Europa, Air France, American Airlines, +16 more

Air Europa, Air France, +17 more

Thursday

Air Europa, Air France, American Airlines, +15 more

Air Europa, Air France, +16 more

Friday

Air Europa, Air France, American Airlines, +14 more

Air Europa, Air France, +15 more

Saturday

Air Europa, Air France, American Airlines, +16 more

Air Europa, Air France, +17 more

Sunday

Air Europa, Air France, American Airlines, +19 more

Air Europa, Air France, +20 more

See more direct flights

Nonstop returns

Panama City Tocumen Intl to South Carolina

Monday

Air Europa, Air France, American Airlines, +19 more

Air Europa, Air France, +20 more

Tuesday

Air Europa, Air France, American Airlines, +16 more

Air Europa, Air France, +17 more

Wednesday

Air Europa, Air France, American Airlines, +16 more

Air Europa, Air France, +17 more

Thursday

Air Europa, Air France, American Airlines, +15 more

Air Europa, Air France, +16 more

Friday

Air Europa, Air France, American Airlines, +14 more

Air Europa, Air France, +15 more

Saturday

Air Europa, Air France, American Airlines, +16 more

Air Europa, Air France, +17 more

Sunday

Air Europa, Air France, American Airlines, +19 more

Air Europa, Air France, +20 more

See more direct flights
See more direct flights

Book cheap flights from South Carolina to Panama City

Recent round-trip flight deals

10/10Thu
1 stopUnited Airlines
8h 19mGSP-PTY
10/14Mon
1 stopUnited Airlines
29h 35mPTY-GSP
$299
9/19Thu
1 stopUnited Airlines
12h 37mGSP-PTY
9/22Sun
1 stopUnited Airlines
28h 44mPTY-GSP
$304
5/28Tue
2 stops
34h 12mCLT-PTY
6/3Mon
2 stops
32h 50mPTY-CLT
$310
6/5Wed
2 stopsAmerican Airlines
19h 05mCHS-PTY
6/11Tue
2 stopsAmerican Airlines
20h 39mPTY-CHS
$315
6/4Tue
2 stopsAmerican Airlines
21h 03mCHS-PTY
6/11Tue
2 stopsAmerican Airlines
20h 39mPTY-CHS
$316
6/4Tue
2 stops
11h 25mCLT-PTY
6/11Tue
2 stops
18h 51mPTY-CLT
$322
9/7Sat
1 stopDelta
7h 10mCHS-PTY
9/11Wed
1 stopDelta
8h 18mPTY-CHS
$332
9/7Sat
1 stopDelta
7h 55mCAE-PTY
9/11Wed
1 stopDelta
8h 39mPTY-CAE
$408
5/31Fri
1 stopCopa Airlines
11h 45mCHS-PTY
6/7Fri
1 stopCopa Airlines
10h 29mPTY-CHS
$1,012
8/12Mon
1 stopCopa Airlines
11h 34mCAE-PTY
8/16Fri
1 stopCopa Airlines
9h 17mPTY-CAE
$1,048

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Recent one-way flight deals

6/4Tue
2 stopsAmerican Airlines
23h 10mCHS-PTY
$124
6/4Tue
1 stopAmerican Airlines
21h 09mCHS-PTY
$125
6/12Wed
2 stops
32h 50mCHS-PTY
$127
6/12Wed
1 stopUnited Airlines
26h 28mCHS-PTY
$136
6/6Thu
2 stopsAmerican Airlines
19h 27mCHS-PTY
$144
7/22Mon
1 stopKLM
19h 40mCHS-PTY
$152
6/4Tue
3 stops
32h 53mCHS-PTY
$165
8/2Fri
1 stopDelta
9h 07mCLT-PTY
$218
5/10Fri
1 stopDelta
11h 18mCLT-PTY
$278
5/10Fri
3 stopsUnited Airlines
14h 30mCLT-PTY
$1,823

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Last minute flights from South Carolina to Panama City

Last minute flight, train and bus deals

5/6Mon
multi-stopAmerican Airlines
18h 03mGSP-PTY
6/8Sat
multi-stopAmerican Airlines
18h 28mPTY-GSP
$323
5/6Mon
multi-stopDelta
7h 56mGSP-PTY
5/11Sat
multi-stopDelta
8h 21mPTY-GSP
$352
5/6Mon
multi-stopDelta
7h 56mGSP-PTY
6/8Sat
multi-stopDelta
8h 42mPTY-GSP
$407
5/6Mon
multi-stopUnited Airlines
9h 16mGSP-PTY
5/11Sat
multi-stopUnited Airlines
10h 26mPTY-GSP
$428
5/6Mon
multi-stopAmerican Airlines
19h 25mGSP-PTY
6/8Sat
multi-stopAmerican Airlines
18h 28mPTY-GSP
$435
5/6Mon
multi-stopAmerican Airlines
18h 03mGSP-PTY
5/11Sat
multi-stopAmerican Airlines
19h 44mPTY-GSP
$450
5/6Mon
multi-stopAmerican Airlines
33h 00mGSP-PTY
5/11Sat
multi-stopAmerican Airlines
28h 27mPTY-GSP
$456
5/6Mon
multi-stopAmerican Airlines
33h 00mGSP-PTY
5/11Sat
multi-stopAmerican Airlines
28h 27mPTY-GSP
$465
5/6Mon
multi-stopAmerican Airlines
18h 03mGSP-PTY
5/11Sat
multi-stopAmerican Airlines
19h 44mPTY-GSP
$495

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Flights to Panama City

Destination:

Panama City (PTY)Panama

Return flight deals:

Panama City - South Carolina

Cabin classes: