Find flights
When to book
FAQs & Tips
Direct Flights
Deals

PTY

Find cheap flights from South Carolina to Panama City from $109

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to Panama City departing on 5/20. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
0 bags
Fri 6/7
Fri 6/14

Search hundreds of travel sites at once for deals on flights to Panama City

In the last 7 days travelers have searched 43,968,530 times on KAYAK, and here is why:

Save 21% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Bundle and saveSave money when you bundle your flight + hotel.

Good to know

Low season

September

High season

December

Cheapest flight

$109
Best time to beat the crowds with an average 15% drop in price.
Most popular time to fly with an average 47% increase in price.
Flight from Greenville to Panama City

FAQs for booking flights from South Carolina to Panama City

  • How does KAYAK find such low prices on flights from South Carolina to Panama City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from South Carolina to Panama City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from South Carolina to Panama City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Panama City from South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from South Carolina to Panama City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Panama City with an airline and back to South Carolina with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from South Carolina to Panama City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Panama City from South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Prefer to fly non-stop from South Carolina to Panama City?

Find which airlines fly direct from South Carolina to Tocumen Intl, which days they fly and book direct flights.

Nonstop departures

South Carolina to Panama City Tocumen Intl

Monday

Air Europa, Air France, American Airlines, +19 more

Air Europa, Air France, +20 more

Tuesday

Air Europa, Air France, American Airlines, +16 more

Air Europa, Air France, +17 more

Wednesday

Air Europa, Air France, American Airlines, +16 more

Air Europa, Air France, +17 more

Thursday

Air Europa, Air France, American Airlines, +15 more

Air Europa, Air France, +16 more

Friday

Air Europa, Air France, American Airlines, +14 more

Air Europa, Air France, +15 more

Saturday

Air Europa, Air France, American Airlines, +16 more

Air Europa, Air France, +17 more

Sunday

Air Europa, Air France, American Airlines, +19 more

Air Europa, Air France, +20 more

See more direct flights

Nonstop returns

Panama City Tocumen Intl to South Carolina

Monday

Air Europa, Air France, American Airlines, +19 more

Air Europa, Air France, +20 more

Tuesday

Air Europa, Air France, American Airlines, +16 more

Air Europa, Air France, +17 more

Wednesday

Air Europa, Air France, American Airlines, +16 more

Air Europa, Air France, +17 more

Thursday

Air Europa, Air France, American Airlines, +15 more

Air Europa, Air France, +16 more

Friday

Air Europa, Air France, American Airlines, +14 more

Air Europa, Air France, +15 more

Saturday

Air Europa, Air France, American Airlines, +16 more

Air Europa, Air France, +17 more

Sunday

Air Europa, Air France, American Airlines, +19 more

Air Europa, Air France, +20 more

See more direct flights
See more direct flights

Book cheap flights from South Carolina to Panama City

Recent round-trip flight deals

9/18Wed
1 stopUnited Airlines
12h 37mGSP-PTY
9/24Tue
1 stopUnited Airlines
10h 24mPTY-GSP
$282
9/18Wed
2 stopsAmerican Airlines
18h 05mGSP-PTY
9/25Wed
2 stopsAmerican Airlines
19h 16mPTY-GSP
$286
9/18Wed
1 stopUnited Airlines
8h 19mGSP-PTY
9/24Tue
1 stopUnited Airlines
28h 44mPTY-GSP
$289
9/19Thu
1 stopUnited Airlines
12h 37mGSP-PTY
9/22Sun
1 stopUnited Airlines
28h 44mPTY-GSP
$294
8/1Thu
1 stopDelta
7h 55mGSP-PTY
8/4Sun
1 stopDelta
8h 33mPTY-GSP
$302
8/15Thu
1 stopDelta
7h 10mCHS-PTY
8/21Wed
1 stopDelta
8h 20mPTY-CHS
$302
5/18Sat
1 stopUnited Airlines
9h 16mGSP-PTY
5/29Wed
1 stopUnited Airlines
23h 02mPTY-GSP
$309
9/7Sat
1 stopDelta
7h 10mCHS-PTY
9/11Wed
1 stopDelta
6h 42mPTY-CHS
$322
5/29Wed
2 stops
34h 12mCLT-PTY
6/3Mon
2 stops
32h 50mPTY-CLT
$470
5/23Thu
2 stops
11h 25mCLT-PTY
5/29Wed
3 stops
14h 40mPTY-CLT
$471

Search by stops

Search by airline

Search by price

Recent one-way flight deals

5/20Mon
1 stopDelta
7h 58mGSP-PTY
$109
5/19Sun
1 stopDelta
17h 49mGSP-PTY
$120
5/17Fri
1 stopDelta
13h 53mGSP-PTY
$129
5/26Sun
1 stopUnited Airlines
23h 57mCHS-PTY
$131
7/5Fri
1 stopDelta
12h 06mCHS-PTY
$139
5/16Thu
1 stopDelta
27h 38mGSP-PTY
$140
7/5Fri
2 stopsAmerican Airlines
19h 27mCHS-PTY
$144
5/16Thu
2 stopsAmerican Airlines
23h 28mGSP-PTY
$145
5/26Sun
3 stops
32h 53mCHS-PTY
$225
5/31Fri
2 stops
28h 52mCLT-PTY
$225

Search by stops

Search by airline

Search by price

Last minute flights from South Carolina to Panama City

Last minute flight, train and bus deals

5/13Mon
multi-stop
25h 22mCLT-PTY
7/30Tue
multi-stop
19h 56mPTY-CLT
$452
5/13Mon
multi-stop
21h 22mCLT-PTY
7/30Tue
multi-stop
19h 56mPTY-CLT
$532
5/13Mon
multi-stopUnited Airlines
7h 55mCLT-PTY
7/30Tue
multi-stopUnited Airlines
9h 13mPTY-CLT
$551
5/13Mon
multi-stop
25h 22mCLT-PTY
7/30Tue
multi-stop
18h 42mPTY-CLT
$572
5/11Sat
multi-stop
30h 12mCLT-PTY
5/19Sun
multi-stop
35h 53mPTY-CLT
$620
5/11Sat
multi-stopDelta
7h 48mCLT-PTY
5/19Sun
multi-stopDelta
8h 32mPTY-CLT
$632
5/11Sat
multi-stop
15h 45mCLT-PTY
5/19Sun
multi-stop
16h 40mPTY-CLT
$740
5/11Sat
multi-stop
15h 45mCLT-PTY
5/19Sun
multi-stop
24h 31mPTY-CLT
$818

Search by stops

Search by airline

Search by price

Flights to Panama City

Destination:

Panama City (PTY)Panama

Return flight deals:

Panama City - South Carolina

Cabin classes: