Martinsburg Hotel's Location Is Secluded and Convenient The Holiday Inn® Martinsburg hotel's location provides guests with a quiet yet convenient destination that is ideal for every type of traveler. While the area may seem rural and removed, there is plenty of excitement in Martinsburg, WV for the hotel's visitors. Martinsburg, West Virginia gives business travelers an array of opportunities. The hotel is positioned right off of I-81, which allows patrons quick commutes to their professional destinations, including the IRS National Computer Center, VA Medical Center, Essroc, United States Coast Guard OSC Procter & Gamble and University Healthcare - Berkeley Medical Center. Travelers can find night-life downtown Martinsburg, West Virginia, just two miles away, providing excellent shopping and dining options. Between Antietam National Battlefield and Harpers Ferry, there is a tremendous number of historically significant sites in the area. Our location enables patrons to enjoy outdoor activities, as well, such as whitewater rafting, golfing and more. In addition to a majestic setting, the Holiday Inn® Martinsburg hotel provides excellent amenities. The indoor pool gives guests the opportunity to relax, while the Business Center and Fitness Center help maintain work and fitness schedules. On-site Heatherfields Restaurant offers delicious dining options, too. Your next visit to West Virginia should include a stay with us.