A world of comfort in the heart of South Orange County. Just a short drive from John Wayne Airport and Irvine Spectrum, Ayres Suites Mission Viejo invites you to experience our personalized service and inviting accommodations. Join Ayres Rewards Today!: Earn free nights fast with Ayres Rewards. You can also choose from gift cards to over 100+ different retailers. With Ayres Hotels, your travel will be truly elevated!