Welcome to the Hampton Inn & Suites Madisonville hotel, located in Madisonville, Kentucky! This hotel is located at Exit 42 off Pennyrile Expressway. Madisonville is the county seat of Hopkins County with a small town atmosphere and the amenities of a much larger city. The town of Madisonville is served directly by the Pennyrile Parkway, US Highway 41, 41A and Kentucky highways 70 and 85. It is a half hour from Interstate 24. The Hampton Inn & Suites Madisonville hotel features a meeting room, indoor swimming pool, state-of-the-art exercise equipment and Suite Shop. This Madisonville Hampton Inn & Suites hotel in Kentucky also features a business center which includes high-speed internet access, fax and copy machine. We love having you here in Kentucky at the Hampton Inn & Suites Madisonville hotel!