Stay at One of the Best Biloxi, MS Hotels With 26 miles of white-sand beaches and 12 exciting casinos, Mississippi's Gulf Coast is full of adventure. From its beautiful Art Deco decor to the first-rate amenities, the full-service Holiday Inn® Biloxi hotel is the perfect choice for your family vacation or business trip. A scenic coastline is just one of the many exciting sites to visit in Biloxi, MS. Our hotel is a short drive from all the casinos, including Beau Rivage, which features more than 2,100 slot machines. Let your kids explore the hands-on displays at Lynn Meadows Discovery Center. The sparkling Gulf of Mexico is a must-see on your trip, and we're just across the street from the water. When you stay at our Biloxi, MS hotel, you have all the tools necessary for a productive business trip. Besides an incredible location, we also provide a Business Center and free Wi-Fi access. Looking for hotels in Biloxi, Mississippi to host your next meeting? We have an elegant conference room that can seat up to 20 people. We want to ensure you have a memorable trip to the Gulf Coast, so we offer all the conveniences you've come to expect. Get an invigorating workout in the Fitness Center or relax in our outdoor pool. At Basil Grill, you can choose from an array of American-style entrees without having to leave our hotel's property! Stay in Biloxi, Mississippi at the Holiday Inn® Biloxi hotel for a great Gulf Coast excursion!