The Best of Upstate Hotels Is in Historic Newberry SC Welcome to the Holiday Inn Express® Hotel & Suites Newberry. As the premier choice among hotels in the Newberry SC area we are conveniently located at exit 76 off of I-26 about 30 minutes north of Columbia and less than an hour south of Greenville SC. Business guests to Newberry SC appreciate our hotel's close proximity to companies including Caterpillar Komatsu Kiswire International Paper Co. Georgia Pacific and Louis Rich. We're just six miles from the Newberry County Memorial Hospital as well. We're also pleased to provide a 24-hour Business Center and two spacious meeting rooms which are suitable for up to 85 people. From the famous Newberry Opera House and the Newberry County Historical Museum to historic downtown and the Country Club of Newberry SC our hotel's guests have much to see and do. Newberry College is just minutes away as well making us the preferred choice for those on college visits in Newberry SC. Our hotel's fantastic amenities including an indoor pool whirlpool and Fitness Center make it easy for travelers to unwind. Be sure to stop by our complimentary Express Start Breakfast Bar each morning for delights like our signature cinnamon rolls and Smart Roast coffee. Few hotels in Newberry SC can provide travelers with these perks backed by the reputable name they trust.