Introduction
When to visit
How to get there
Where to stay
Renting a car

Seneca travel guide

Seneca Tourism | Seneca Guide

You're Going to Love Seneca

With a population of 8,102, Seneca is a must-see destination in South Carolina, United States. It is among the most popular tourist destinations in the country. We recommend you stay at least 3 days in order to fully appreciate everything Seneca has to offer.

When to visit Seneca

Seneca in January
Estimated hotel price
$97
1 night at 3-star hotel
Seneca in January
Estimated hotel price
$97
1 night at 3-star hotel

How to Get to Seneca

Plane

Although Seneca doesn’t have its own airport, you can fly to Greenville (GSP), which is located 44 miles from Seneca. Greenville is the most popular, with regular flights from American Airlines, Delta, WestJet and other airlines departing from the United States. The shortest domestic flight to Seneca departs from Sarasota and takes around 1h 39m.

Train

Amtrak is the only carrier operating train routes to Seneca. The train journey from Seneca to Charlotte takes 2h 29m and costs around $34 for a one-way ticket. When coming by train from Atlanta, expect to pay about $40 for a 2h 49m trip.

Car

Another option to get to Seneca is to pick up a car rental from Atlanta, which is about 104 miles from Seneca. You’ll find branches of Routes Car & Truck Rentals and Turo, among others, in Atlanta.

Bus

You can travel by bus to Seneca using FlixBus or Greyhound. From Atlanta, the bus ride to Seneca takes 155 miles and will cost you around $71. From Nashville, the ticket costs about $58 for a journey of 520 miles.

Plane

Although Seneca doesn’t have its own airport, you can fly to Greenville (GSP), which is located 44 miles from Seneca. Greenville is the most popular, with regular flights from American Airlines, Delta, WestJet and other airlines departing from the United States. The shortest domestic flight to Seneca departs from Sarasota and takes around 1h 39m.

Train

Amtrak is the only carrier operating train routes to Seneca. The train journey from Seneca to Charlotte takes 2h 29m and costs around $34 for a one-way ticket. When coming by train from Atlanta, expect to pay about $40 for a 2h 49m trip.

Car

Another option to get to Seneca is to pick up a car rental from Atlanta, which is about 104 miles from Seneca. You’ll find branches of Routes Car & Truck Rentals and Turo, among others, in Atlanta.

Bus

You can travel by bus to Seneca using FlixBus or Greyhound. From Atlanta, the bus ride to Seneca takes 155 miles and will cost you around $71. From Nashville, the ticket costs about $58 for a journey of 520 miles.

Airports near Seneca

GSPGreenville
AVLAsheville Regional
TYSKnoxville McGhee Tyson

Airlines serving Seneca

Lufthansa
Good (7,046 reviews)
KLM
Good (1,334 reviews)
British Airways
Good (6,842 reviews)
Delta
Excellent (7,934 reviews)
Air France
Good (1,446 reviews)
Austrian Airlines
Good (780 reviews)
United Airlines
Good (8,697 reviews)
Emirates
Excellent (3,215 reviews)
Qatar Airways
Good (3,563 reviews)
Air Canada
Good (9,248 reviews)
Scandinavian Airlines
Good (1,349 reviews)
Brussels Airlines
Good (346 reviews)
Finnair
Good (1,275 reviews)
Alaska Airlines
Excellent (9,969 reviews)
Ethiopian Air
Good (769 reviews)
JetBlue
Good (2,922 reviews)
Aer Lingus
Good (1,076 reviews)
Frontier
Okay (3,287 reviews)
Avianca
Good (2,317 reviews)
ANA
Excellent (852 reviews)
Show more
Find flights to Seneca

Where to stay in Seneca

If you’re on a budget, well-reviewed accommodations include Tru by Hilton Seneca Clemson and Fairfield Inn & Suites Seneca Clemson Univ Area.

Where to stay in popular areas of Seneca

Most booked hotels in Seneca

See all
Tru by Hilton Seneca Clemson
2 stars
Excellent (8.8, 185 reviews)
$124+
View
Hampton Inn & Suites Seneca-Clemson Area
2 stars
Excellent (8.5, 225 reviews)
$139+
View
Quality Inn Seneca Us-123
2 stars
Good (7.8, 457 reviews)
$96+
View
Best Western Seneca-Clemson
2 stars
Good (7.7, 199 reviews)
$103+
View
Days Inn by Wyndham Seneca / Clemson Area
2 stars
Good (6, 342 reviews)
$71+
View

Renting a car in Seneca

Renting a car in Seneca costs $61 per day, on average, or $183 if you want to rent if for 3 days.

It’s generally cheaper to rent your vehicle outside the airport: locations in the city are around 21% cheaper than airport locations in Seneca.

Expect to pay $3.41 per gallon in Seneca (average price from the past 30 days). Depending on the size of your rental car, filling up the tank will cost between $40.88 and $54.51. The most frequently booked car type in Seneca is Mini (Chrysler Pacifica or similar). If you’re looking to save money, though, keep in mind that Compact rental cars (Nissan Versa or similar) are, on average, 22% cheaper than other rental car types in the city.

Renting a car in Seneca costs $61 per day, on average, or $183 if you want to rent if for 3 days.

It’s generally cheaper to rent your vehicle outside the airport: locations in the city are around 21% cheaper than airport locations in Seneca.

Expect to pay $3.41 per gallon in Seneca (average price from the past 30 days). Depending on the size of your rental car, filling up the tank will cost between $40.88 and $54.51. The most frequently booked car type in Seneca is Mini (Chrysler Pacifica or similar). If you’re looking to save money, though, keep in mind that Compact rental cars (Nissan Versa or similar) are, on average, 22% cheaper than other rental car types in the city.

Best car rental deals in Seneca

Economy

2 Adults, 2 Bags

$51/day

Economy

Compact

4 Adults, 2 Bags

$52/day

Compact
Find car rentals in Seneca

Seneca Travel Guide - View the KAYAK Seneca city guide for the best Seneca travel tips. To help you organize your Seneca trip ideas, this Seneca visitors guide provides travel information and trip tips about how to get there, where to stay, what to do, where to eat and more.