Behind every great day is a great night at the Comfort Inn hotel in Defiance, OH, near ConAgra Foods, Defiance College and Defiance Regional Medical Center. When traveling for work, you can take advantage of our copy and fax services, and enjoy complimentary amenities like daily hot breakfast, weekday newspapers, an exercise room and indoor heated pool. Laundry facilities are available, as is ample parking for buses and trucks. Our guestrooms have the features you need to get refreshed and ready to take on the day, like refrigerators, microwaves, coffee makers, irons and ironing boards. Also, earn rewards including free nights and gift cards with our Choice Privileges Rewards program. Our hotel is 100% smoke free.