$133 Find Cheap Flights from Buffalo to Missouri

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Buffalo to Missouri departing on 4/6. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Missouri

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Buffalo to Missouri, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Buffalo to Missouri, as well as popular online travel agencies
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Cheap Flights from Buffalo to Missouri

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
St. Louis
St. Louis1 stop$257
Kansas City
Kansas City1 stop$320
Springfield
Springfield1 stop$310
Columbia
Columbia1 stop$318
St. Louis
St. Louis1 stop$257
Kansas City
Kansas City1 stop$320
Springfield
Springfield1 stop$310
Columbia
Columbia1 stop$318

Book Cheap Buffalo to Missouri Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Buffalo to Missouri that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Buffalo to Missouri

Mon, Apr 20 - Wed, Apr 22
Frontier Logo
11:19 am - 11:19 pm
BUF
-
STL
13h 00m
1 stop
Frontier Logo
4:59 pm - 7:26 pm
STL
-
BUF
25h 27m
1 stop
$257Frontier
Tue, Apr 14 - Sun, Apr 19
Frontier Logo
1:56 pm - 6:50 am
BUF
-
STL
17h 54m
1 stop
Frontier Logo
4:59 pm - 12:42 pm
STL
-
BUF
42h 43m
2 stops
$271Frontier
Mon, Apr 20 - Wed, Apr 22
Southwest Logo
4:00 pm - 10:45 pm
BUF
-
STL
7h 45m
2 stops
Southwest Logo
5:35 am - 10:20 am
STL
-
BUF
3h 45m
1 stop
$304Southwest
Tue, Jun 2 - Thu, Jun 4
Southwest Logo
11:00 am - 7:15 pm
BUF
-
STL
9h 15m
2 stops
Southwest Logo
4:35 pm - 12:10 am
STL
-
BUF
6h 35m
2 stops
$309Southwest
Tue, May 5 - Sat, May 9
American Airlines Logo
6:00 am - 9:51 am
BUF
-
SGF
4h 51m
1 stop
American Airlines Logo
3:36 pm - 11:50 pm
SGF
-
BUF
7h 14m
1 stop
$310American Airlines
Fri, May 1 - Mon, May 4
American Airlines Logo
6:00 pm - 9:30 pm
BUF
-
COU
4h 30m
1 stop
American Airlines Logo
6:00 am - 2:21 pm
COU
-
BUF
7h 21m
1 stop
$318American Airlines
Mon, Jun 1 - Tue, Jun 9
Delta Logo
7:39 pm - 11:16 am
BUF
-
MCI
16h 37m
1 stop
Delta Logo
5:40 pm - 11:03 pm
MCI
-
BUF
4h 23m
1 stop
$320Delta
Mon, Jun 1 - Sat, Jun 6
Delta Logo
7:39 pm - 11:16 am
BUF
-
MCI
16h 37m
1 stop
Delta Logo
11:50 am - 8:48 pm
MCI
-
BUF
7h 58m
1 stop
$355Delta
Thu, Apr 23 - Sat, Apr 25
United Airlines Logo
7:00 am - 10:27 am
BUF
-
MCI
4h 27m
1 stop
United Airlines Logo
3:15 pm - 8:49 pm
MCI
-
BUF
4h 34m
1 stop
$361United Airlines
Wed, Apr 1 - Sun, Apr 5
United Airlines Logo
6:00 am - 2:35 pm
BUF
-
SGF
9h 35m
2 stops
United Airlines Logo
1:33 pm - 11:10 pm
SGF
-
BUF
8h 37m
1 stop
$374United Airlines
Booking Insights

KAYAK's insights & trends for Buffalo to Missouri flights

Get data-powered insights and trends into flights from Buffalo to Missouri to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Buffalo to Missouri?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Buffalo to Missouri, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Buffalo to Missouri is September, when tickets cost $316 (return) on average. On the other hand, the most expensive months are March and February, when the average cost of round-trip tickets is $575 and $489 respectively.

Good to know

Low seasonJanuary
Cheapest flight$133
Most popular time to fly with an average 12% increase in price.
Flight from Buffalo to St. Louis

FAQs - booking Missouri flights

  • How does KAYAK find such low prices on flights from Buffalo to Missouri?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Buffalo to Missouri.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Buffalo to Missouri?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Buffalo to Missouri is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Buffalo to Missouri?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Buffalo to Missouri with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Buffalo to Missouri?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Buffalo to Missouri up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 4 airlines serving from Buffalo to Missouri

 
See real verified KAYAK customer reviews for airlines flying from Buffalo to Missouri. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Buffalo to Missouri? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4324 reviews
7.5Entertainment
8.6Crew
7.0Food
8.1Boarding
8.0Comfort
Airline reviews

Southwest was greaat! The most expensive but the least upsetting for those we were flying to see.

10.0 ExcellentMartie, Mar 2026
LGB - BNA
Read more Southwest reviews

Southwest was greaat! The most expensive but the least upsetting for those we were flying to see.

I flew twice this week on Southwest, was delayed over 2 hours both ways. From Pittsburgh to Chicago it was due to weather but the gate agents, pilot etc were great at updating everyone. Today from Midway to Pittsburgh the plane had come from an international location, kept getting delayed, no information was given until we were delayed for the third time. It was ridiculous, whoever scheduled that plane to fly to Pittsburgh after didn’t consider a lot of things.

Boarding was easy. The seats are small and fairly uncomfortable

I was supposed to be on a later flight. When I showed up at the gate, the woman working there was extremely helpful getting moved up to this earlier flight.

We had a 5 hour delay on the tarmac in Baltimore

Long layover between flights to Long Island from BWI - need better coordination between flights

I elected to pay for the upgrades and found very little difference

The new seating arrangement is so over priced for what you get.

The problem with the seat assignments is that there were a lot of rows in the front that were empty but my row at the back was full. Just not so pleasant.

No food or entertainment, just a quick 40 minute flight. A little bumpy due to Santa Ana winds but pilot has no control over that. Good flight and landing!

Love delta smaller commuter plane so no entertainment and paid wifi on MKE-LGA leg was extremely unreliable and slow

Delayed. Hot. Passenger next to me was so large I couldn’t move.

The flight went very well, but the flight attendants didn't serve and food or drinks other than 1st class due to rough air but to be honest it wasn't that bumpy and I felt that they could've at least offered water and coffee perhaps. Also serving 1st class only is a bad look. I've been in 1st class many times and I would've felt that if the turbulence was too rough for the main cabin, it would be too rough for 1st class too.

There was an unruly family behind us that made the short flight miserable!!! The cabin crew did nothing to contain it.

My seatback screen didn’t work so that sucked because that’s what I was going to do on the plane.

The whole experience was excellent. As it most often is with Delta

There’s not much to say about a one hour flight. This is a connection from LA to RNO that I missed the previous night due to a mechanical check delay on my originating flight from JFK to LAX. The short flight itself was fine. Instructions from the pilot and crew were per usual. The coffee was barely lukewarm, which possibly was purposeful so we would down it quickly. Bags were already on carousel upon reaching baggage claim, which was excellent.

Boarding and crew were fantastic, but I paid for a window seat with no window. Seat 11D on a CRJ-900 apparently does not have a window. Lesson learned.

Delta flights recently are always delayed AND at jfk tney get the gates further away (need To walk 20’ to get to them/all the way at the end of the terminal). Not sure whats happening but price doesnt match experience!

boarded at 5:30 pm, pushed away from gate at 6pm ... takeoff was not until ~6:45pm; disappointing

My flight was canceled a few hours before boarding. I was rebooked on Copa airlines and missed an important meeting .

Good quick flight on a small but comfortable plane. I'm 6'3 and had plenty of space.

Experience was great - no complaints. Took off on time, landed early. Got to the gate relatively quickly - took a little bit of extra time to deplane but nothing excessive.

Economy plus was so cramped I could not use my laptop. It was beyond bad.

OK, we were delayed and had to de plane and reboard.

United is one airline which regardless of how many separate United tickets in existence, if one flight breaks down, the airline will take care of all the flights.

Both our flights were delayed. Almost didn’t get in the second flight. Staff was rude to the bone.

Both my flight where delayed Had 25min to make it to my transfer flight

Everything was on time and service on the flight was great!

Wifi Bluetooth features for watching in flight movie was horrible. Screen kept blacking out no connection of sound although it said connected. Other than that smooth trip .

There was no inflight service. Once we landed we were delayed to find a gate for an hour and a half which was 1/2 the total time in the air.

Snow delayed boarding several times, which I understand happens. Issue I had was that after we did board, pilot told us we were going to roll out to be de-iced, then on our way. We were de-iced once, taxied to the tarmac and then stopped. Sat for another 30 minutes or so, the another de-icing. Then we rolled out to a parking spot, only to sit for another hour due to a traffic stop in DCA, which I'm confident they knew would happen before we boarded. Pilot gave no updates other than we had to hold, attendants did speak to the crew, but when asked, said the pilot would be updating us. We on the ground in the plane waiting for over 2 hours. They did communicate that bathrooms would be open, but no other news until we left. Would have been better to be up front about status.

It was good experience this time. The flight was on time.

Small plane, poor meal choices for first class, bad terminal and boarding experience at LAX

The gate agent had a really bad attitude and refused to help me get on the standby list. She just handed me a card and said I needed to call a number. I asked her to help with the AA app on my phone and she just shrugged and said she didnt know. After a few phone calls, I eventually just went to a different gate agent on the other side of the terminal and got the help I needed.

Boarding delayed 20 minutes for no reason, no wifi, in flight entertainment, or snacks / waters?

One day, I do so hope for a gluten free snack! Seems like with the rest of the world FINALLY figuring out what gluten free is, American Airlines would too. Fingers crossed!!

This flight captain and crew were amazing, started ahead of time of departure and reached 30 mins before arrival time. Amazing!

I would like the crew to talk LESS over the PA and specifically about credit card offers. I am trying to work, sleep, watch a movie and the PA was booming about a credit card offer. Could we go back to the days when the customer was more important than selling a credit card?

My seat tv didn’t work the whole trip. And the seat space is too small despite being seated at the front.

Everything you need to know for your flight from Buffalo to Missouri

Information on your arrival and departure airports