$560 Find Cheap Flights from Knoxville to the Cayman Islands

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to the Cayman Islands departing on 7/17. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Book Cheap Knoxville to the Cayman Islands Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Knoxville to the Cayman Islands that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to the Cayman Islands

Fri, Jul 17 - Sat, Jul 25
American Airlines Logo
6:30 pm - 11:00 am
TYS
-
GCM
17h 30m
1 stop
American Airlines Logo
12:50 pm - 1:18 pm
GCM
-
TYS
23h 28m
1 stop
$560American Airlines
Sat, Mar 28 - Sat, Apr 4
American Airlines Logo
2:54 pm - 10:40 am
TYS
-
GCM
20h 46m
1 stop
American Airlines Logo
7:45 am - 11:59 pm
GCM
-
TYS
15h 14m
1 stop
$588American Airlines
Sat, Mar 28 - Sat, Apr 4
American Airlines Logo
2:54 pm - 10:40 am
TYS
-
GCM
20h 46m
1 stop
American Airlines Logo
7:45 am - 11:59 pm
GCM
-
TYS
15h 14m
1 stop
$603American Airlines
Fri, Jul 17 - Sat, Jul 25
American Airlines Logo
6:30 pm - 11:00 am
TYS
-
GCM
17h 30m
1 stop
American Airlines Logo
2:10 pm - 8:35 am
GCM
-
TYS
17h 25m
2 stops
$619American Airlines
Sat, Jun 13 - Sat, Jun 20
American Airlines Logo
8:09 pm - 1:32 pm
TYS
-
GCM
18h 23m
1 stop
American Airlines Logo
2:10 pm - 8:35 am
GCM
-
TYS
17h 25m
2 stops
$668American Airlines
Mon, Feb 16 - Sun, Feb 22
American Airlines Logo
5:45 am - 8:15 pm
TYS
-
GCM
14h 30m
1 stop
American Airlines Logo
4:25 pm - 11:31 am
GCM
-
TYS
19h 06m
1 stop
$673American Airlines
Mon, Feb 16 - Sun, Feb 22
American Airlines Logo
6:05 am - 8:15 pm
TYS
-
GCM
14h 10m
2 stops
American Airlines Logo
4:25 pm - 3:37 pm
GCM
-
TYS
23h 12m
1 stop
$678American Airlines
Sun, Feb 22 - Thu, Feb 26
United Airlines Logo
6:45 am - 1:45 pm
TYS
-
GCM
7h 00m
1 stop
United Airlines Logo
2:50 pm - 10:12 am
GCM
-
TYS
19h 22m
1 stop
$691United Airlines
Sat, Jun 13 - Sat, Jun 20
American Airlines Logo
8:09 pm - 1:32 pm
TYS
-
GCM
18h 23m
1 stop
American Airlines Logo
2:10 pm - 11:59 pm
GCM
-
TYS
8h 49m
1 stop
$706American Airlines
Fri, Feb 13 - Tue, Feb 17
American Airlines Logo
5:45 am - 8:15 pm
TYS
-
GCM
14h 30m
1 stop
American Airlines Logo
8:45 am - 11:59 pm
GCM
-
TYS
15h 14m
1 stop
$716American Airlines
Booking Insights

KAYAK's insights & trends for Knoxville to the Cayman Islands flights

Get data-powered insights and trends into flights from Knoxville to the Cayman Islands to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Knoxville to the Cayman Islands?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Knoxville to the Cayman Islands were found on American Airlines ($588) and United Airlines ($691).

Find deals

Good to know

Low seasonFebruary
Cheapest flight$560
Best time to beat the crowds with an average 20% drop in price.
Most popular time to fly with an average 18% increase in price.
Flight from Knoxville to George Town

FAQs - booking Cayman Islands flights

  • How does KAYAK find such low prices on flights from Knoxville to the Cayman Islands?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to the Cayman Islands.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to the Cayman Islands?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Knoxville to the Cayman Islands is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to the Cayman Islands?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Knoxville to the Cayman Islands with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to the Cayman Islands?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Knoxville to the Cayman Islands up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Knoxville to the Cayman Islands

 
Need help choosing which airline to fly with from Knoxville to the Cayman Islands? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 11207 reviews
7.5Boarding
8.0Crew
7.2Comfort
6.4Food
6.9Entertainment
Airline reviews

It would be nice to have some low carb options in the snacks.

10.0 ExcellentLori, Jan 2026
SMF - PHX
Read more American Airlines reviews

It would be nice to have some low carb options in the snacks.

I was trying to take 2 one and a half hour one way trips and I experienced almost 20 delays over the course of those two trips. Only a few of them were due to weather the rest was disorganization

No gates avail at DFW so our incoming had to wait 30 mins for a plane to push back because they Had mechanical. We boarded 90 mins delayed and then we had a mechanical. Come on American…do better. Also at my seat the tray table had not been cleaned. Floor had not been cleaned. But captain and flight Att were very picture and apologetic.

Crew was helpful and cheerful especially when they had no refreshments to work with. The plane was never serviced and had nothing but limited water and coffee onboard. For the price point, a concern of services.

Flight was smooth, quick and felt safe. The 2 delays not happening would have been better but I guess that happens in the airline industry

Flight was canceled. I asked to be rerouted to OKC and then took an Uber.

AA did not allow to board a flight because my connecting flight from DFW had been canceled. I got on another flight to another city. No service on the plane and I did not use their entertainment system.

On time on a day with lots of weather cancellations on other flights. Thank you for getting me home during a winter storm!

Don't change gate multiple times make people run across the airport. Announce delays in a timely manner. Have maintenance crew ready. Don't delay and keep passengers on the plane for 3 hrs. on tarmac.

The plane was experiencing problems with the HVAC system, it was very cold in the front of the plane and very hot in the back.

Everything you need to know for your flight from Knoxville to the Cayman Islands

Information on your arrival and departure airports

Knoxville (TYS)