$216 Find Cheap Flights from Knoxville to the Cayman Islands

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to the Cayman Islands departing on 5/2. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Book Cheap Knoxville to the Cayman Islands Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Knoxville to the Cayman Islands that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to the Cayman Islands

Wed, Jul 15 - Wed, Jul 29
Delta Logo
7:33 am - 11:31 am
TYS
-
GCM
4h 58m
1 stop
Delta Logo
12:56 pm - 8:12 pm
GCM
-
TYS
6h 16m
1 stop
$591Delta
Mon, Jun 1 - Wed, Jun 10
Multiple Airlines Logo
8:00 am - 5:20 pm
TYS
-
GCM
10h 20m
1 stop
Multiple Airlines Logo
11:30 am - 8:30 pm
GCM
-
TYS
32h 00m
2 stops
$603Multiple Airlines
Tue, Jun 16 - Tue, Jun 23
American Airlines Logo
6:00 am - 4:11 pm
TYS
-
GCM
11h 11m
1 stop
American Airlines Logo
5:12 pm - 11:59 pm
GCM
-
TYS
5h 47m
1 stop
$609American Airlines
Sat, Jun 20 - Fri, Jun 26
American Airlines Logo
7:59 pm - 11:30 am
TYS
-
GCM
16h 31m
1 stop
American Airlines Logo
12:01 pm - 8:34 am
GCM
-
TYS
19h 33m
2 stops
$614American Airlines
Thu, Jul 16 - Wed, Jul 29
Delta Logo
5:40 am - 11:31 am
TYS
-
GCM
6h 51m
1 stop
Delta Logo
12:56 pm - 11:52 pm
GCM
-
TYS
9h 56m
1 stop
$616Delta
Sat, Sep 19 - Sat, Sep 26
American Airlines Logo
5:09 pm - 10:50 am
TYS
-
GCM
18h 41m
2 stops
American Airlines Logo
12:35 pm - 7:04 pm
GCM
-
TYS
5h 29m
1 stop
$621American Airlines
Mon, Jun 1 - Wed, Jun 10
American Airlines Logo
7:59 pm - 11:30 am
TYS
-
GCM
16h 31m
1 stop
American Airlines Logo
12:01 pm - 11:59 pm
GCM
-
TYS
10h 58m
1 stop
$626American Airlines
Mon, Jun 1 - Tue, Jun 9
American Airlines Logo
7:32 am - 4:11 pm
TYS
-
GCM
9h 39m
2 stops
American Airlines Logo
5:12 pm - 11:59 pm
GCM
-
TYS
5h 47m
1 stop
$631American Airlines
Mon, Jun 15 - Mon, Jun 22
American Airlines Logo
6:00 am - 4:11 pm
TYS
-
GCM
11h 11m
1 stop
American Airlines Logo
5:12 pm - 11:59 pm
GCM
-
TYS
5h 47m
1 stop
$634American Airlines
Sun, Jun 14 - Sun, Jun 21
American Airlines Logo
6:00 am - 11:01 am
TYS
-
GCM
6h 01m
1 stop
American Airlines Logo
5:12 pm - 11:59 pm
GCM
-
TYS
5h 47m
1 stop
$639American Airlines
Booking Insights

KAYAK's insights & trends for Knoxville to the Cayman Islands flights

Get data-powered insights and trends into flights from Knoxville to the Cayman Islands to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Knoxville to the Cayman Islands?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Knoxville to the Cayman Islands were found on Delta ($591) and American Airlines ($609).

Find deals

Good to know

Low seasonFebruary
Cheapest flight$216
Best time to beat the crowds with an average 21% drop in price.
Most popular time to fly and prices are also 9% lower on average.
Flight from Knoxville to George Town

FAQs - booking Cayman Islands flights

  • How does KAYAK find such low prices on flights from Knoxville to the Cayman Islands?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to the Cayman Islands.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to the Cayman Islands?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Knoxville to the Cayman Islands is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to the Cayman Islands?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Knoxville to the Cayman Islands with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to the Cayman Islands?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Knoxville to the Cayman Islands up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Knoxville to the Cayman Islands

 
Need help choosing which airline to fly with from Knoxville to the Cayman Islands? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.1
American AirlinesOverall score based on 11520 reviews
7.2Comfort
7.9Crew
6.9Entertainment
7.5Boarding
6.4Food
Airline reviews

The flight changed gates multiple times and flight had to be delayed multiple times

4.0 OkayFaraz, Mar 2026
DFW - BWI
Read more American Airlines reviews

The flight changed gates multiple times and flight had to be delayed multiple times

We called Kayak for a change due to the TSA situation in Atlanta. What we got was a canceled return flight (in error) and we had to find the mistake. Not happy with Kayak who blamed it on AA.

Tv screens and movie selection v good. Friendly staff. They were really worried about max capacity and room for carryons. That is never fun but i had no problem finding space when I boarded.

I was in last row so that is never great bc the person in front of me leaned his seat all the way back into me.

Delayed for mechanical and no updates on what was happening and how long the delay might be.

My flight from LGA was cancelled and my rebooked flight from JFK was delayed numerous times. I will now be getting home after 2am.

Flight was delayed half hour before boarding, but when I checked flight aware the plane that would Pick us up had a delay of more than an hour. AA should let us know in advance to avoid waiting several hours in the airport

On the return flight, arriving in Denver we sat on the tarmac in Denver for over 20 minutes.

Typical AA - late by 90+ mn. Gate changed twice... Changed the departure time 6 times No explanation, no communication on reasons for delay I travel with AA twice a year... and it is consistently very poor.. I will continue to use AA only when i have to.

The flight attendant in business class was excellent! Professional, friendly and attentive.

Everything you need to know for your flight from Knoxville to the Cayman Islands

Information on your arrival and departure airports

Knoxville (TYS)