$223 Find Cheap Flights from Knoxville to the Cayman Islands

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to the Cayman Islands departing on 7/31. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Book Cheap Knoxville to the Cayman Islands Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Knoxville to the Cayman Islands that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to the Cayman Islands

Mon, Jul 27 - Sat, Aug 1
Multiple Airlines Logo
12:53 pm - 4:05 pm
TYS
-
GCM
28h 12m
2 stops
Multiple Airlines Logo
11:25 am - 10:57 pm
GCM
-
TYS
10h 32m
1 stop
$561Multiple Airlines
Mon, Jul 27 - Fri, Jul 31
Multiple Airlines Logo
8:30 am - 5:20 pm
TYS
-
GCM
9h 50m
1 stop
Multiple Airlines Logo
11:25 am - 11:19 pm
GCM
-
TYS
10h 54m
1 stop
$575Multiple Airlines
Mon, Jul 27 - Fri, Jul 31
Multiple Airlines Logo
12:53 pm - 4:05 pm
TYS
-
GCM
28h 12m
2 stops
Multiple Airlines Logo
11:25 am - 11:19 pm
GCM
-
TYS
10h 54m
1 stop
$587Multiple Airlines
Sat, Jun 20 - Fri, Jun 26
American Airlines Logo
7:59 pm - 11:30 am
TYS
-
GCM
16h 31m
1 stop
American Airlines Logo
5:12 pm - 11:59 pm
GCM
-
TYS
5h 47m
1 stop
$631American Airlines
Sat, Jun 6 - Fri, Jun 12
American Airlines Logo
8:11 pm - 1:35 pm
TYS
-
GCM
18h 24m
1 stop
American Airlines Logo
5:11 pm - 11:59 pm
GCM
-
TYS
5h 48m
1 stop
$633American Airlines
Sat, Jun 20 - Fri, Jun 26
American Airlines Logo
7:59 pm - 11:30 am
TYS
-
GCM
16h 31m
1 stop
American Airlines Logo
12:01 pm - 8:34 am
GCM
-
TYS
19h 33m
2 stops
$636American Airlines
Sat, Jun 6 - Fri, Jun 12
American Airlines Logo
7:49 pm - 4:11 pm
TYS
-
GCM
21h 22m
1 stop
American Airlines Logo
5:11 pm - 12:26 pm
GCM
-
TYS
18h 15m
2 stops
$637American Airlines
Mon, Jul 27 - Fri, Jul 31
American Airlines Logo
5:00 am - 11:25 am
TYS
-
GCM
7h 25m
1 stop
American Airlines Logo
5:10 pm - 11:59 pm
GCM
-
TYS
5h 49m
1 stop
$646American Airlines
Sat, Jul 11 - Thu, Jul 16
American Airlines Logo
7:48 pm - 11:00 am
TYS
-
GCM
16h 12m
1 stop
American Airlines Logo
2:41 pm - 11:52 pm
GCM
-
TYS
8h 11m
1 stop
$647American Airlines
Mon, Jul 27 - Fri, Jul 31
American Airlines Logo
6:00 am - 4:10 pm
TYS
-
GCM
11h 10m
1 stop
American Airlines Logo
5:10 pm - 10:38 am
GCM
-
TYS
16h 28m
2 stops
$651American Airlines
Booking Insights

KAYAK's insights & trends for Knoxville to the Cayman Islands flights

Get data-powered insights and trends into flights from Knoxville to the Cayman Islands to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Knoxville to the Cayman Islands?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Knoxville to the Cayman Islands, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Knoxville to the Cayman Islands is July, when tickets cost $0 (return) on average. On the other hand, the most expensive months are November and May, when the average cost of round-trip tickets is $684 and $659 respectively.

Find deals

Good to know

Low seasonFebruary
Cheapest flight$223
Best time to beat the crowds with an average 22% drop in price.
Most popular time to fly and prices are also 10% lower on average.
Flight from Knoxville to George Town

FAQs - booking Cayman Islands flights

  • How does KAYAK find such low prices on flights from Knoxville to the Cayman Islands?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to the Cayman Islands.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to the Cayman Islands?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Knoxville to the Cayman Islands is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to the Cayman Islands?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Knoxville to the Cayman Islands with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to the Cayman Islands?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Knoxville to the Cayman Islands up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Knoxville to the Cayman Islands

 
Need help choosing which airline to fly with from Knoxville to the Cayman Islands? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.1
American AirlinesOverall score based on 11667 reviews
7.2Comfort
7.9Crew
6.9Entertainment
7.5Boarding
6.4Food
Airline reviews

The passenger in front of of me reclined their seat back all the way the entire flight. Their headrest was in my face the entire flight! I barely had room for the little plastic cup of water to fit on my tray table; can you make the seats and space between the rows any smaller??? You can’t even get up to use the restroom! Worst flight I’ve had in a very long time!

6.0 GoodAnonymous, May 2026
DTW - DFW
Read more American Airlines reviews

The passenger in front of of me reclined their seat back all the way the entire flight. Their headrest was in my face the entire flight! I barely had room for the little plastic cup of water to fit on my tray table; can you make the seats and space between the rows any smaller??? You can’t even get up to use the restroom! Worst flight I’ve had in a very long time!

We had several flights and they were all on-time and flawless

My Frequent Flyer nber wasn't put on as I was told it was..... This resulted in a last group boarding and no priority tags on My bags.

Premium Economy Good crew, good service, excellent food. Seat back screen just not bright enough.

Terrible steward... Plane was quite empty... I asked to move "back" in the plane and the steward said no... Unnecessary power trip of mediocre people.

Flight was delayed an no one cares, or try to help passengers to get the conexión.

Our flight was cancelled while we are on our way to the airport. So, no notice. We were rescheduled to another airline with a 2 hour later takeoff and so arrived at our destination on time. We pre-paid American Airlines $190 to upgrade our seats. No refund. So no use for AA or Kayak.

The small flights with Valet Luggage has a poor service

Terrible, horrible, disappointing- without telling us they changed planes and moved and separated our seats to opposite sides - said they changed seats putting us together - got to airport to find no, they did not - we sat opposing sides of plane - food overly salty to inedible, never saw stewardess but once - it was terrible

not sure why you ask about food, I n3ver get food on flights except maybe cookies or pretzels. wifi was slow and in and out most of the flight not good.

Everything you need to know for your flight from Knoxville to the Cayman Islands

Information on your arrival and departure airports

Knoxville (TYS)