$546 Find Cheap Flights from Knoxville to the Cayman Islands

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to the Cayman Islands departing on 2/15. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

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Flight Deals

Book Cheap Knoxville to the Cayman Islands Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Knoxville to the Cayman Islands that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to the Cayman Islands

Sun, Feb 15 - Sun, Feb 22
American Airlines Logo
5:51 am - 2:04 pmTYS-GCM
8h 13m1 stop
American Airlines Logo
4:35 pm - 11:13 amGCM-TYS
18h 38m1 stop
$546American Airlines
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Tue, Mar 10 - Wed, Mar 11
Delta Logo
5:30 am - 11:35 amTYS-GCM
7h 05m1 stop
Delta Logo
1:00 pm - 9:43 pmGCM-TYS
7h 43m1 stop
$550Delta
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Sun, Feb 15 - Sun, Feb 22
American Airlines Logo
7:58 am - 7:51 pmTYS-GCM
11h 53m2 stops
American Airlines Logo
4:35 pm - 11:13 amGCM-TYS
18h 38m1 stop
$568American Airlines
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Sat, Mar 28 - Sat, Apr 4
American Airlines Logo
8:31 pm - 11:15 amTYS-GCM
15h 44m1 stop
American Airlines Logo
3:15 pm - 10:10 pmGCM-TYS
5h 55m1 stop
$575American Airlines
Find Deal
Tue, Mar 10 - Wed, Mar 11
American Airlines Logo
6:58 am - 2:20 pmTYS-GCM
8h 22m2 stops
American Airlines Logo
2:55 pm - 2:05 pmGCM-TYS
22h 10m2 stops
$665American Airlines
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Mon, Mar 9 - Fri, Mar 13
American Airlines Logo
8:31 pm - 11:15 amTYS-GCM
15h 44m1 stop
American Airlines Logo
2:55 pm - 9:29 pmGCM-TYS
5h 34m1 stop
$680American Airlines
Find Deal
Mon, Mar 9 - Fri, Mar 13
American Airlines Logo
8:31 pm - 11:15 amTYS-GCM
15h 44m1 stop
American Airlines Logo
8:30 am - 7:02 pmGCM-TYS
9h 32m2 stops
$685American Airlines
Find Deal
Sun, Feb 15 - Sun, Feb 22
Multiple Airlines Logo
6:10 am - 1:40 pmTYS-GCM
7h 30m1 stop
Multiple Airlines Logo
2:35 pm - 6:32 pmGCM-TYS
27h 57m3 stops
$692Multiple Airlines
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Mon, Apr 6 - Wed, Apr 8
American Airlines Logo
5:49 am - 1:19 pmTYS-GCM
8h 30m1 stop
American Airlines Logo
3:15 pm - 11:14 pmGCM-TYS
6h 59m1 stop
$695American Airlines
Find Deal
Mon, Mar 9 - Fri, Mar 13
American Airlines Logo
8:02 am - 6:51 pmTYS-GCM
11h 49m2 stops
American Airlines Logo
8:30 am - 7:02 pmGCM-TYS
9h 32m2 stops
$703American Airlines
Find Deal
Booking Insights

KAYAK's insights & trends for Knoxville to the Cayman Islands flights

Get data-powered insights and trends into flights from Knoxville to the Cayman Islands to help you find the cheapest flights, the best time to fly and much more.

Which airlines fly non-stop between Knoxville and Cayman Islands?

Airline and price data is aggregated from results in KAYAK’s search results from the last 2 weeks for round-trip flights from Knoxville to the Cayman Islands.

There are 2 airlines that fly nonstop from Knoxville to the Cayman Islands. They are American Airlines and Delta. The cheapest airline for this route is Delta, with the best round-trip deal found costing $469 and arriving in George Town (GCM). On average, Delta offers the best prices for nonstop flights between Knoxville and Cayman Islands.

Which airlines provide the cheapest flights from Knoxville to the Cayman Islands?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Knoxville to the Cayman Islands were found on American Airlines ($546) and Delta ($550).

Good to know

Cheapest flight$546
Most popular time to fly with an average 14% increase in price.
Flight from Knoxville to George Town

FAQs - booking Cayman Islands flights

  • How does KAYAK find such low prices on flights from Knoxville to the Cayman Islands?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to the Cayman Islands.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to the Cayman Islands?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Knoxville to the Cayman Islands is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to the Cayman Islands?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Knoxville to the Cayman Islands with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to the Cayman Islands?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Knoxville to the Cayman Islands up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to the Cayman Islands?

    The cheapest time of day to fly to the Cayman Islands is generally in the morning, when round-trip flights cost $611 on average. The most expensive time of day to fly to the Cayman Islands is generally in the morning, which is peak travel time and where the average cost of a ticket is $611.

Reviews of the top airlines flying from Knoxville to the Cayman Islands

 
Need help choosing which airline to fly with from Knoxville to the Cayman Islands? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 7981 reviews
7.3Food
8.5Crew
7.9Entertainment
7.9Comfort
8.2Boarding
Airline reviews

The aircraft interior is old and tired on this aircraft. The entertainment system never worked despite the crews attempt to reset the system.

6.0 GoodDavid, Oct 2025JFK - KEF
Read more Delta reviews

The aircraft interior is old and tired on this aircraft. The entertainment system never worked despite the crews attempt to reset the system.

The flight used a B767 with a very old interior from before 2014. The entertainment system did not work at all during the flight despite attempts to reset the system. It was like they flew this route just to be competitive.

Old plane and old configuration/seats but still comfortable for a morning flight

They changed planes and the new plane couldn’t carry enough fuel to fly across the country so we had to stop in Kansas City to refuel. Flight was delayed .

Flight was too crowded and seats are too small, especially since passengrs are getting larger. Having a middle seat is ALWAYS tough! Woman on my left was large & kept creeping in to my space. Flight personnel were great! Have more savory rather than sweet snacks please.

Flight was crowded and the woman sitting on my left was large & kept crouching in to my space. You need bigger seats or smaller passengers to fit into the seats you DO have! Snack were OK. Would appreciate if airlines had more savory rather than sweet snacks, thank you!

Delayed flight (1hour) plus a long layover after an overnight flight with no backup plane available.

We were delayed, which I think had to do with air traffic control. Otherwise, everything was great.

The boarding process needs to be refined. Sometimes the gate crew calls out the zones and then flip to showing the.zones boarding on the gate monitor display. So, unless you are huddled around the gate lanes watching the monitor, you could miss your boarding zone. Suggest the zones be announced each time a new zone is allowed to board.

The boarding process needs to be refined. Sometimes the gate crew call out the boarding zone, and then flip to the monitor to show which zones are boarding. So unless everyone is gathered around to see the monitor there is usually confusion as wi which zones are boarding.

Disliked having to wait a little longer to disembark from the plan when we landed in London

Typically flights with AA are good. The staff are pleasant, welcoming, and efficient.

A couple ladies from the crew were so rude and nasty. Thought they were mad at having to be there especially if you asked a question. This will make me think twice next time if I book a flight with you.

Delays to take off and to leave the plane after landing added a lot of time to this flight.

Poor seat in rear of aircraft Food at Admiral’s Club Terminal D at DFW inedible

Always seated jammed in rear of aircraft Admirals Club food at DFW terminal D was absolute worst food experience and I pay $600/year to eat this dried out junk

Flight was delayed because of a bird strike. They had another plane available within 45 minutes.

Mostly good. Flight was crowded but Airline personnel were very friendly & accommodating. It would be good to have savory snacks rather than just sweet Biscoff cookies.

It was a typical flight. We had a delay which seems to be the normality now. And we had no in flight service due to conditions.

Flight attendants on this flight were very attentive and friendly

Everything you need to know for your flight from Knoxville to the Cayman Islands

Information on your arrival and departure airports

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