$530 Find Cheap Flights from Knoxville to the Cayman Islands

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to the Cayman Islands departing on 3/28. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Book Cheap Knoxville to the Cayman Islands Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Knoxville to the Cayman Islands that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to the Cayman Islands

Sat, Mar 28 - Sat, Apr 4
Delta Logo
5:30 am - 9:45 am
TYS
-
GCM
5h 15m1 stop
Delta Logo
2:30 pm - 11:51 pm
GCM
-
TYS
8h 21m1 stop
$530Delta
Sat, Mar 28 - Sat, Apr 4
American Airlines Logo
7:39 pm - 1:25 pm
TYS
-
GCM
18h 46m1 stop
American Airlines Logo
7:45 am - 11:59 pm
GCM
-
TYS
15h 14m1 stop
$587American Airlines
Fri, Jan 23 - Mon, Jan 26
Delta Logo
5:40 am - 12:40 pm
TYS
-
GCM
7h 00m1 stop
Delta Logo
2:05 pm - 11:45 pm
GCM
-
TYS
9h 40m1 stop
$600Delta
Fri, Jan 23 - Mon, Jan 26
American Airlines Logo
10:11 am - 8:20 pm
TYS
-
GCM
10h 09m2 stops
American Airlines Logo
12:50 pm - 10:54 pm
GCM
-
TYS
10h 04m2 stops
$605American Airlines
Thu, Feb 12 - Mon, Feb 16
American Airlines Logo
6:02 am - 8:15 pm
TYS
-
GCM
14h 13m1 stop
American Airlines Logo
4:25 pm - 11:50 pm
GCM
-
TYS
7h 25m1 stop
$615American Airlines
Thu, Feb 12 - Mon, Feb 16
American Airlines Logo
8:13 am - 8:15 pm
TYS
-
GCM
12h 02m2 stops
American Airlines Logo
12:55 pm - 6:32 pm
GCM
-
TYS
5h 37m1 stop
$620American Airlines
Sun, Jan 4 - Wed, Jan 7
American Airlines Logo
5:00 am - 11:57 am
TYS
-
GCM
6h 57m1 stop
American Airlines Logo
1:05 pm - 9:44 pm
GCM
-
TYS
8h 39m2 stops
$625American Airlines
Sun, Feb 1 - Thu, Feb 5
United Airlines Logo
6:45 am - 1:45 pm
TYS
-
GCM
7h 00m1 stop
United Airlines Logo
2:50 pm - 10:32 am
GCM
-
TYS
19h 42m1 stop
$669United Airlines
Sun, Jan 4 - Wed, Jan 7
American Airlines Logo
5:42 am - 2:21 pm
TYS
-
GCM
8h 39m2 stops
American Airlines Logo
8:50 am - 9:21 pm
GCM
-
TYS
12h 31m2 stops
$670American Airlines
Thu, Feb 12 - Mon, Feb 16
American Airlines Logo
8:13 am - 8:15 pm
TYS
-
GCM
12h 02m2 stops
American Airlines Logo
12:55 pm - 11:54 pm
GCM
-
TYS
10h 59m2 stops
$673American Airlines
Booking Insights

KAYAK's insights & trends for Knoxville to the Cayman Islands flights

Get data-powered insights and trends into flights from Knoxville to the Cayman Islands to help you find the cheapest flights, the best time to fly and much more.

Which airlines fly non-stop between Knoxville and Cayman Islands?

Airline and price data is aggregated from results in KAYAK’s search results from the last 2 weeks for round-trip flights from Knoxville to the Cayman Islands.

There is just one airline that flies from Knoxville to the Cayman Islands direct and that is American Airlines. The best round-trip deal found from American Airlines for the route is to George Town (GCM) and costs $503.

Which airlines provide the cheapest flights from Knoxville to the Cayman Islands?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Knoxville to the Cayman Islands were found on American Airlines ($533) and Delta ($600).

Find deals

Good to know

Low seasonFebruary
Cheapest flight$530
Best time to beat the crowds with an average 20% drop in price.
Most popular time to fly with an average 18% increase in price.
Flight from Knoxville to George Town

FAQs - booking Cayman Islands flights

  • How does KAYAK find such low prices on flights from Knoxville to the Cayman Islands?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to the Cayman Islands.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to the Cayman Islands?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Knoxville to the Cayman Islands is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to the Cayman Islands?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Knoxville to the Cayman Islands with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to the Cayman Islands?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Knoxville to the Cayman Islands up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to the Cayman Islands?

    The cheapest time of day to fly to the Cayman Islands is generally in the morning, when round-trip flights cost $611 on average. The most expensive time of day to fly to the Cayman Islands is generally in the morning, which is peak travel time and where the average cost of a ticket is $611.

Reviews of the top airline flying from Knoxville to the Cayman Islands

 
Need help choosing which airline to fly with from Knoxville to the Cayman Islands? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 11054 reviews
6.9Entertainment
6.4Food
8.0Crew
7.5Boarding
7.2Comfort
Airline reviews

The boarding by groups is pointless. The first two groups worked fine, but almost Noone boarded in goups three thru five leaving the vast majority boarding when group six was called. It defeated the purpose of spreading out the crowd.

6.0 GoodDan, Dec 2025
ORD - ALO
Read more American Airlines reviews

The boarding by groups is pointless. The first two groups worked fine, but almost Noone boarded in goups three thru five leaving the vast majority boarding when group six was called. It defeated the purpose of spreading out the crowd.

I don’t know who decides what food to serve on these flights but I would be so embarrassed if I served this to anyone and call it food…

For whatever reason, the flight was not catered -we were told it would be a 45 minute delay waiting for catering - so no food. There were opened candy and peanuts in the seatback pocket. Flight landed early in DFW but due to the assigned gate not being available, we sat on the ground for 30 minutes waiting for the gate to open - making the flight actually arrive at the gate late.

Not great. Booked Extra seats and got nothing extra at all. It’s basically a big budget airline.

The pilot greased the landing and the crew was fantastic.

I bought wifi and most of the flight could not even use it my apps would just spin. I couldn't even listen to music. super frustrating.

delayed due to weather. Could not communicate with family since the wifi was broken

Experience was good, however I had a delay due to weather happening and had to re purchase a seat on a new plane for a higher price (could be my own issue and misunderstanding) but other than that situation. First time flyer (by myself) was terrific!! The last from ORD to ALO didn't have wifi, but it was only 45 minutes so I'm sure that was part of the reason. Overall my experience was great! Next time I will remember to buy tickets with longer layovers. The delays really saved my overall anxiety. :)

Flight was delayed 17 hours due to aircraft issues. American did provide hotel, transportation and meals, 3 hours past boarding time, but it took us another hour to get the vouchers.

Flight was on time is the only good thing. Person loading the plane called 1-6 to board at the same time, made it chaotic. Plane was too small for even putting backpacks in overhead. Seat for normal sized people were too small. The WIFI didn't work. When we landed had to wait because not enough ground crew.

Everything you need to know for your flight from Knoxville to the Cayman Islands

Information on your arrival and departure airports

Knoxville (TYS)