$232 Find Cheap Flights from Knoxville to the Cayman Islands

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to the Cayman Islands departing on 3/9. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Book Cheap Knoxville to the Cayman Islands Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Knoxville to the Cayman Islands that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to the Cayman Islands

Sat, Mar 28 - Sat, Apr 4
Multiple Airlines Logo
9:36 pm - 12:57 pm
TYS
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GCM
16h 21m
1 stop
Multiple Airlines Logo
1:15 pm - 11:35 pm
GCM
-
TYS
33h 20m
2 stops
$554Multiple Airlines
Sat, Mar 28 - Sat, Apr 4
Multiple Airlines Logo
9:36 pm - 12:57 pm
TYS
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GCM
16h 21m
1 stop
Multiple Airlines Logo
1:15 pm - 11:35 pm
GCM
-
TYS
33h 20m
2 stops
$558Multiple Airlines
Sat, Mar 28 - Sat, Apr 4
Multiple Airlines Logo
9:36 pm - 12:57 pm
TYS
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GCM
16h 21m
1 stop
Multiple Airlines Logo
1:15 pm - 11:35 pm
GCM
-
TYS
33h 20m
2 stops
$570Multiple Airlines
Sat, Mar 28 - Sat, Apr 4
Multiple Airlines Logo
9:36 pm - 12:57 pm
TYS
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GCM
16h 21m
1 stop
Multiple Airlines Logo
1:15 pm - 1:05 pm
GCM
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TYS
22h 50m
2 stops
$576Multiple Airlines
Mon, Apr 13 - Wed, Apr 22
United Airlines Logo
7:00 am - 12:45 pm
TYS
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GCM
6h 45m
1 stop
United Airlines Logo
1:35 pm - 11:41 pm
GCM
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TYS
9h 06m
1 stop
$589United Airlines
Wed, Mar 25 - Wed, Apr 1
United Airlines Logo
9:00 am - 3:30 pm
TYS
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GCM
7h 30m
1 stop
United Airlines Logo
1:50 pm - 11:03 pm
GCM
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TYS
8h 13m
1 stop
$591United Airlines
Thu, Apr 16 - Wed, Apr 22
Multiple Airlines Logo
4:31 pm - 4:05 pm
TYS
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GCM
24h 34m
1 stop
Multiple Airlines Logo
11:30 am - 3:41 pm
GCM
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TYS
27h 11m
2 stops
$600Multiple Airlines
Thu, Apr 16 - Wed, Apr 22
American Airlines Logo
7:00 am - 11:31 am
TYS
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GCM
5h 31m
1 stop
American Airlines Logo
12:35 pm - 11:55 pm
GCM
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TYS
10h 20m
1 stop
$602American Airlines
Thu, Jun 4 - Sun, Jun 14
American Airlines Logo
6:00 am - 11:02 am
TYS
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GCM
6h 02m
1 stop
American Airlines Logo
12:02 pm - 11:59 pm
GCM
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TYS
10h 57m
1 stop
$606American Airlines
Mon, Apr 13 - Wed, Apr 22
American Airlines Logo
8:48 pm - 1:10 pm
TYS
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GCM
17h 22m
2 stops
American Airlines Logo
12:00 pm - 10:24 pm
GCM
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TYS
9h 24m
2 stops
$609American Airlines
Booking Insights

KAYAK's insights & trends for Knoxville to the Cayman Islands flights

Get data-powered insights and trends into flights from Knoxville to the Cayman Islands to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Knoxville to the Cayman Islands?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Knoxville to the Cayman Islands were found on United Airlines ($589) and American Airlines ($606).

Good to know

Low seasonFebruary
Cheapest flight$232
Best time to beat the crowds with an average 23% drop in price.
Most popular time to fly with an average 15% increase in price.
Flight from Knoxville to George Town

FAQs - booking Cayman Islands flights

  • How does KAYAK find such low prices on flights from Knoxville to the Cayman Islands?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to the Cayman Islands.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to the Cayman Islands?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Knoxville to the Cayman Islands is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to the Cayman Islands?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Knoxville to the Cayman Islands with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to the Cayman Islands?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Knoxville to the Cayman Islands up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Knoxville to the Cayman Islands

 
Need help choosing which airline to fly with from Knoxville to the Cayman Islands? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 11352 reviews
6.4Food
8.0Crew
7.2Comfort
7.5Boarding
6.9Entertainment
Airline reviews

Lack of gluten free options in food service. I have Celiac disease and it appears you no longer offer special meals for people with dietary restrictions. I am a frequent flyer traveling into and out of Omaha airport. I have noticed over the course of several months that although our flight typically arrives ahead of schedule (awesome job AA!) - we typically sit on the runway for several minutes waiting for the ground crew to get in place. Not sure if it is a ground crew issue or a gate availability issue (due to construction at this airport). Seems to be more of a ground crew being on time issue.

8.0 ExcellentKathryn, Feb 2026
PHX - OMA
Read more American Airlines reviews

Lack of gluten free options in food service. I have Celiac disease and it appears you no longer offer special meals for people with dietary restrictions. I am a frequent flyer traveling into and out of Omaha airport. I have noticed over the course of several months that although our flight typically arrives ahead of schedule (awesome job AA!) - we typically sit on the runway for several minutes waiting for the ground crew to get in place. Not sure if it is a ground crew issue or a gate availability issue (due to construction at this airport). Seems to be more of a ground crew being on time issue.

Arrived early picked up my bag in a few minutes- great trip - thank you

Flight boarded, departed and landed on time. Excellent service from flight attendant in FIRST

Boarding is always an ordeal. Less dogs on flights. I am highly allergic to dogs and cats. Why are there so many animals these days?

Flight to Tampa was delayed taking off due to plane arriving late but no other issues

There was a delay with the plan which cause the flight to leave later and once arrived in Chicago there was another delay and some passengers missed their connecting flights

Massimo, flight attendant was very authentic, attentive - wonderful. Food/wrap was just okay.

Worst experience ever. Flight could not land in Charlotte for what we were told was a ground stop. Had to be diverted to Raleigh to refuel. Strangely during ground stop, our connecting flight had no issue taking off on time causing us to miss our flight. We were told there were no other flights that day to our final destination and that two days out was the next one. The only flights to get us there were from Chicago the next morning. Completely opposite direction but it was a direct flight. So we get flown to Chicago and have to find a hotel in our own dime. The flight in the morning was also delayed. Thankfully only a short time. The non too of all this, our luggage did not arrive by the time we were there. Communication was terrible, through the entire trip. Complete incompetence. Will never fly American again.

Horrible. Got delayed many hours because their pilot wasn't trained for night landing at the airport and a rain delay made it a night landing. We have to wait hours for a qualified crew. They give us 12 dollar meal vouchers but most everything in the airport was closed and definitely more expensive than the vouchers.

I am an AA flyer for a very long time... AA has yet to disappoint.

Everything you need to know for your flight from Knoxville to the Cayman Islands

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