$578 Find Cheap Flights from Knoxville to Istanbul

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to Istanbul departing on 3/11. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Istanbul

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Istanbul, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Istanbul, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$578
British Airways
Wed 3/11Wed 3/18
TYS - IST • 2 stops
Top airlines
British Airways
Cheapest • from $578 (round-trip)
Delta
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
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Booking Insights
Flight Deals

Cheap Flights from Knoxville to Istanbul (TYS-IST)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Knoxville to Istanbul that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to Istanbul

Wed, Mar 11 - Wed, Mar 18
British Airways Logo
4:02 pm - 5:25 pm
TYS
-
IST
18h 23m
2 stops
British Airways Logo
7:35 am - 9:05 pm
IST
-
TYS
20h 30m
2 stops
$578British Airways
Tue, Mar 3 - Tue, Mar 10
KLM Logo
1:00 pm - 5:25 pm
TYS
-
SAW
20h 25m
2 stops
KLM Logo
9:00 am - 9:16 am
SAW
-
TYS
31h 16m
2 stops
$736KLM
Tue, Mar 3 - Tue, Mar 10
Multiple Airlines Logo
1:00 pm - 4:55 pm
TYS
-
IST
19h 55m
2 stops
Multiple Airlines Logo
4:50 am - 11:57 pm
IST
-
TYS
26h 07m
2 stops
$740Multiple Airlines
Wed, Feb 25 - Sun, Mar 1
United Airlines Logo
9:40 am - 6:05 pm
TYS
-
IST
24h 25m
2 stops
United Airlines Logo
6:30 am - 10:12 am
IST
-
TYS
35h 42m
2 stops
$778United Airlines
Wed, Feb 25 - Sun, Mar 1
United Airlines Logo
11:41 am - 6:05 pm
TYS
-
IST
22h 24m
2 stops
United Airlines Logo
6:30 am - 10:12 am
IST
-
TYS
35h 42m
2 stops
$779United Airlines
Mon, Mar 30 - Sun, Sep 20
Lufthansa Logo
7:20 pm - 9:25 pm
TYS
-
IST
19h 05m
2 stops
Lufthansa Logo
5:55 pm - 11:59 pm
IST
-
TYS
37h 04m
2 stops
$924Lufthansa
Thu, Mar 12 - Thu, Mar 19
United Airlines Logo
9:40 am - 6:05 pm
TYS
-
IST
25h 25m
2 stops
United Airlines Logo
6:30 am - 10:49 am
IST
-
TYS
35h 19m
2 stops
$938United Airlines
Sun, Mar 1 - Thu, Mar 5
Lufthansa Logo
7:05 am - 10:45 pm
TYS
-
IST
31h 40m
2 stops
Lufthansa Logo
6:30 am - 8:47 pm
IST
-
TYS
22h 17m
2 stops
$1,015Lufthansa
Fri, Mar 27 - Fri, Apr 3
Delta Logo
6:38 pm - 3:25 am
TYS
-
IST
25h 47m
2 stops
Delta Logo
4:25 am - 11:57 pm
IST
-
TYS
26h 32m
2 stops
$1,053Delta
Sun, Mar 1 - Thu, Mar 5
Multiple Airlines Logo
1:00 pm - 5:25 pm
TYS
-
SAW
20h 25m
2 stops
Multiple Airlines Logo
9:00 am - 8:55 pm
SAW
-
TYS
19h 55m
2 stops
$1,258Multiple Airlines
Booking Insights

KAYAK's insights & trends for Knoxville to Istanbul flights

Get data-powered insights and trends into flights from Knoxville to Istanbul to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Knoxville to Istanbul?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Knoxville to Istanbul were found on British Airways ($578) and KLM ($736).

Good to know

Cheapest flight$578
Flight from Knoxville to Istanbul Airport

When to book flights from Knoxville to Istanbul

Are your dates flexible? Find out the best times to travel from Knoxville to Istanbul based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Knoxville to Istanbul

  • What is the cheapest flight from Knoxville to Istanbul?

    In the last 3 days, the lowest price for a flight from Knoxville to Istanbul was $578 for a round-trip ticket.

  • Do I need a passport to fly between Knoxville and Istanbul?

    Yes

  • Which airports will I be using when flying from Knoxville to Istanbul?

    When flying out of Knoxville you will be using Knoxville McGhee Tyson. You will be landing at one of these airports: Istanbul or Istanbul Sabiha Gokcen.

  • Which aircraft models fly most regularly from Knoxville to Istanbul?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Knoxville to Istanbul?

    SkyTeam, Star Alliance, and oneworld are the airline alliances operating flights between Knoxville and Istanbul, with SkyTeam being the most commonly used for this route.

  • How does KAYAK find such low prices on flights from Knoxville to Istanbul?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to Istanbul.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to Istanbul?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Istanbul from Knoxville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to Istanbul?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Istanbul with an airline and back to Knoxville with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to Istanbul?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Istanbul from Knoxville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 4 airlines serving from Knoxville to Istanbul

 
See real verified KAYAK customer reviews for airlines flying from Knoxville to Istanbul. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Knoxville to Istanbul? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8197 reviews
8.1Boarding
7.8Entertainment
7.2Food
8.5Crew
7.9Comfort
Airline reviews

This was my first time flying Delta ever and I had a great experience!

10.0 ExcellentAnna, Feb 2026
TPA - DTW
Read more Delta reviews

This was my first time flying Delta ever and I had a great experience!

Smallest leg room I've ever had on a plane.

They took all carry-on luggage from Groups 6 -9 - I was group 5 and waiting in line to board - they made me check my luggage too. That then went to baggage claim and delayed departure from the airport. There was overhead room in my seating area - Delta over reacted. Also, had a gentleman next to me that took up 1/2 my seat.

Excellent!!! Aeromexico is a great airline. What was not that good is the service provided by Kayak. It is never clear and not easy to manage.

Flight delay was frustrating, also you cannot checkin online without delta app, web browser check-in throw errors

The gate agent was most helpful in getting me on to fly standby. I greatly appreciate it.

bulkhead seat had very little legroom - even in bsiness class.

The plane was an older model, so it wasn’t as comfortable as others. The flight attendants were not helpful during onboarding. It was a full flight so there was chaos finding space for baggage.

Sorry I didn't realize I was writing a review for each leg. Please see my previous review - it applies to the entire flight, not just a single leg.

This is the first time I've been disappointed with Delta. I was called by Delta to see if I would volunteer to change flights since my original flight home was overbooked. I accepted. The modified booking only provided me a 35 minute layover - when you subtract the fact that boarding closes for a flight 15 minutes early, that gave me 20 minutes to run for one end of the airport to the other. I barely made it. On the 2.5 hour flight to Tampa, the crew repeatedly let us know over the intercom that they cannot serve drinks or snacks due to safety/turbulence. I would have accepted this reason if they did not CONTINUALLY SERVE DRINKS AND COOKED FOOD to First class. If safety is the excuse then the entire plane should be strapped in for safety. On top of this the air conditioning vents were not working correctly and the plane was uncomfortably warm. I love Delta and am a loyal Delta traveler, and I have never had an experience like this. I don't know if there's a disconnect between availability among third-party sites like KAYAK and the airlines or what, but when overbooking causes issues like this for travelers it should be reviewed and changes to the booking process should be made. I blame BOTH KAYAK and Delta for this terrible experience.

Very disappointing given gate agent behavior. Filed a formal complaint with United.

Do not like the size of the overhead bin. I think staff should monitor the size of suitcases that are being carried on by passengers to ensure they meet the size requirement.

Crew was great (professional, attentive, prompt). Snacks for 4 hrs flight is deplorable.

Flight delayed. WiFi connectivity very poor if not existant. Last minute arrival forced me to run to catch my connection.

Both of my flights arrived early and check in process was smooth

Terrible. No customer service, no food, no drinks on a 6 hour premier economy booking.

Short flight, but no drink/snack service. The flights both going and coming were delayed.

Much better than Spirit. I was please by the easy fast check in and boarding

Check-in and in-flight staff were better than average. The seat was a fair size but too hard and not enough padding. The cushion/pillow provided is poor (thin and seems to be disposable ,it provides no effective cushioning or support). Food was OK-ish but no choice of inflight snacks and no easy place to get drinks other than water (I could ask for juice by intruding into the staff area at the back of the plane) Entertainment was very good actually. Overall better than I expected from a US-based airline (sorry!) but compared to ANA or Singapore it was so-so. (I live in Japan so they are my comparative airlines)

Everything was on time Will use united again for sure

Didn't get a seat assignment until the last minute even though i picked a seat.

American has been able to implement an algorithm that makes it possible for nearly every one of my evening flights to be late. Congratulations!

I was on a small regional flight from Detroit to Philadelphia. When we landed the outside cruise needed to turn something off with the engine, which took quite a long time. Then, when they allowed us to get off the plane it was outside. They took their time, unloading all the luggage and waited till they unloaded all the luggage before they brought it over to us. It was 9 o’clock at night freezing cold out, and there was no proactive hustle to try to get people their luggage. It was really one of the worst experiences I think I’ve ever had with American until a manager came over. I don’t think they were going to even consider pulling the luggage over to the people that had been waiting outside for at least 10 minutes in the freezing cold.

The flight was fine, once we got underway. It was more than hour delayed

Beverage service was not good. Also just one service in 5 hr 30 min flight. No ask fir water ir anything beside one time beverage service.

Waited for oxygen tanks for 30 minutes after boarding was complete.

The seats are too uncomfortable for anyone over 5ft 8in. I'm 5'10" with a back and hip issue and I was in pai for the full duration of the flight.

The flight was on time/early, attentive crew, and everything overall went smoothly. Disappointed that WIFI was not working for the flight.

One day, I do so hope for a gluten free snack! Seems like with the rest of the world FINALLY figuring out what gluten free is, American Airlines would too. Fingers crossed!!

The flight was significantly delayed for 6.5 hours because of snow. There was no communication once the plane returned to the gate regarding when the flight would resume. Other flights were departing while our flight was being unloaded for reasons unknown. Our flight also seemed out of the queue regarding further deicing, refueling, and waiting to Taxi to the runway.

They had us seating down for one hour just waiting on the plane

Flying with BA is always a good experience—even in economy class. It is better if in business and first class. Timely, breeze through security and timely connections

We waited at BOS at the gate for an hour and couldn’t get a drink or anything. Once in the air the service, food and ride was excellent.

My enetertainmnet screen was broken. Lost my bags. Almost missed my flight do to connection issues with (despite a request) ZERO help from crew. Food was edible. Potatoes pretty good even

Our Jackson, Mississippi to Dallas Fort Worth flight was delayed on 1/19/26.. This was changed to Jackson to Charlotte in the last minute because of this delay. This started some kind of disconnect between American Airlines and British Airways bookings. We could not go past the passport control in London Heathrow. I had to go to the counter and waited for more than 30 minutes to get a new boarding pass. Problems did not end there. Somehow our entire return flight was canceled by someone. I had to make several phone calls over several days to fix the problem – this was not easy from India. Looks like there was some kind of disconnect between two airlines or some agent did not do it right. I’m anxious to know what went wrong.

The issue was not with BA it was with the link yoiu sent fopr booking the flight

Loved the boarding option from Business class lounge, experience on flight was excellent, plenty of good food choices

Getting the boarding passes between the BA and AA apps was very clunky.

The airline was not clear about a new departure time so we got to the airport early anyway. The flight left early which was great because of weather. The check in process was very easy and staff were friendly and helpful. The crew was great and our flight was very good.

Awful it always is unfortunately is the only way to fly direct to london

Everything you need to know for your flight from Knoxville to Istanbul

Information on your arrival and departure airports