Which airports can I use when flying from Knoxville to La Crosse?

Flights from Knoxville to La Crosse usually depart from Knoxville McGhee Tyson (TYS) and arrive at La Crosse (LSE).

What cabin classes can I book on flights from Knoxville to La Crosse?

Only Economy Class is available on flights from Knoxville to La Crosse.

Which airports do connecting flights from Knoxville to La Crosse pass through?

Most connecting flights from Knoxville to La Crosse pass through Chicago O'Hare Intl (ORD), which handles 100% of one-stop traffic on this route. Other layover airports each see under 5%.

Can I save money by using flexible dates for flights from Knoxville to La Crosse?

Yes. Being flexible with your travel dates can save you up to 59% on the Knoxville to La Crosse route. Tuesday is the cheapest departure day at $345 round-trip on average, while Monday is the most expensive at $836, a difference of $491. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

Do I need a passport to fly from Knoxville to La Crosse?

No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID, or another TSA-accepted form of identification.

Have flight prices from Knoxville to La Crosse changed much recently?

Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $350 to $1,027. That means the highest observed fare was about 3x higher than the lowest one.

What is the time difference between Knoxville and La Crosse?

La Crosse is 1 hour behind Knoxville (Central Time vs Eastern Time). Plan for the time shift when scheduling connections or first-day activities.

What is the cheapest airline to fly from Knoxville to La Crosse?

Allegiant Air ($350) and American Airlines ($461) are the cheapest airlines to fly round-trip from Knoxville to La Crosse according to KAYAK data over the last 5 days.

What is the cheapest layover airport when flying from Knoxville to La Crosse?

Flights via Chicago O'Hare Intl (ORD) offer the most affordable fares, with an average round-trip price of $596. Based on KAYAK data over the past 3 months.

When flying from Knoxville to La Crosse which airport offers the shortest layover?

Chicago O'Hare Intl (ORD) had the shortest average connection time for Knoxville to La Crosse layovers at 250 minutes over the past 3 months.

$350 CHEAP FLIGHTS from Knoxville to La Crosse (TYS - LSE)

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Cheapest round-trip

$350

Typical prices: $508-$836

Allegiant Air

Sun 9/30Thu 10/4

TYS - LSE • 1 stop

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Cheap Flights from Knoxville to La Crosse (TYS-LSE)

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Recent round-trip flight deals from Knoxville to La Crosse

Wed, Sep 30 - Sun, Oct 4

1:51 pm - 8:56 amTYS Knoxville McGhee Tyson-LSE La Crosse

20h 05m1 stop Orlando Sanford Intl

11:06 am - 9:03 pmLSE La Crosse-TYS Knoxville McGhee Tyson

8h 57m1 stop Orlando Sanford Intl

$350Allegiant Air

Wed, Sep 30 - Sun, Oct 4

1:51 pm - 8:56 amTYS Knoxville McGhee Tyson-LSE La Crosse

20h 05m1 stop Orlando Sanford Intl

11:06 am - 1:07 pmLSE La Crosse-TYS Knoxville McGhee Tyson

25h 01m2 stops Orlando Sanford Intl Key West

$368Allegiant Air

Wed, Sep 30 - Sun, Oct 4

2:43 pm - 12:20 amTYS Knoxville McGhee Tyson-LSE La Crosse

10h 37m2 stops Dallas/Fort Worth Chicago O'Hare Intl

5:53 am - 5:36 pmLSE La Crosse-TYS Knoxville McGhee Tyson

10h 43m2 stops Chicago O'Hare Intl Washington, D.C. Reagan-National

$461American Airlines

Fri, Oct 9 - Mon, Oct 12

6:55 pm - 11:59 pmTYS Knoxville McGhee Tyson-LSE La Crosse

6h 04m1 stop Chicago O'Hare Intl