TYS - LSE

$521 Find Cheap Flights from Knoxville to La Crosse

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to La Crosse departing on 6/18. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to La Crosse

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to La Crosse, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to La Crosse, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$521
United Airlines
Thu 6/18Sun 6/21
TYS - LSE • 1 stop
Top airlines
United Airlines
Cheapest • from $521 (round-trip)
American Airlines
Best reviews • 7.2 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Knoxville and La Crosse. You'll need at least 1 connection.
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We hope you love your trip to La Crosse!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Knoxville to La Crosse (TYS-LSE)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Knoxville to La Crosse that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to La Crosse

Thu, Jun 18 - Sun, Jun 21
United Airlines Logo
8:20 am - 9:08 am
TYS
-
LSE
25h 48m
1 stop
United Airlines Logo
6:15 am - 5:01 pm
LSE
-
TYS
9h 46m
1 stop
$521United Airlines
Thu, Jun 18 - Sun, Jun 21
American Airlines Logo
7:12 am - 4:59 pm
TYS
-
LSE
10h 47m
2 stops
American Airlines Logo
11:39 am - 6:17 pm
LSE
-
TYS
5h 38m
1 stop
$594American Airlines
Thu, Jun 18 - Sun, Jun 21
American Airlines Logo
7:12 am - 4:59 pm
TYS
-
LSE
10h 47m
2 stops
American Airlines Logo
11:39 am - 11:59 pm
LSE
-
TYS
11h 20m
2 stops
$722American Airlines
Booking Insights

KAYAK's insights & trends for Knoxville to La Crosse flights

Get data-powered insights and trends into flights from Knoxville to La Crosse to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Knoxville to La Crosse?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Knoxville to La Crosse were found on United Airlines ($521) and American Airlines ($594).

Good to know

Cheapest flight$521
Flight from Knoxville to La Crosse

When to book flights from Knoxville to La Crosse

Are your dates flexible? Find out the best times to travel from Knoxville to La Crosse based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Knoxville to La Crosse

  • What is the cheapest flight from Knoxville to La Crosse?

    In the last 3 days, the lowest price for a flight from Knoxville to La Crosse was $521 for a round-trip ticket.

  • Do I need a passport to fly between Knoxville and La Crosse?

    No

  • Which aircraft models fly most regularly from Knoxville to La Crosse?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Knoxville to La Crosse?

    oneworld is the only airline alliance operating flights between Knoxville and La Crosse.

  • How does KAYAK find such low prices on flights from Knoxville to La Crosse?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to La Crosse.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to La Crosse?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to La Crosse from Knoxville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to La Crosse?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to La Crosse with an airline and back to Knoxville with another airline. Booking your flights between Knoxville and LSE can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to La Crosse?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to La Crosse from Knoxville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Knoxville to La Crosse

 
See real verified KAYAK customer reviews for airlines flying from Knoxville to La Crosse. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Knoxville to La Crosse? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 11334 reviews
7.2Comfort
6.4Food
7.5Boarding
8.0Crew
6.9Entertainment
Airline reviews

Experience was great. The best part is the free Wi-Fi connection which helps me to work on the flight

10.0 ExcellentKavindra, Feb 2026
LAX - CMH
Read more American Airlines reviews

Experience was great. The best part is the free Wi-Fi connection which helps me to work on the flight

The gate agent had a really bad attitude and refused to help me get on the standby list. She just handed me a card and said I needed to call a number. I asked her to help with the AA app on my phone and she just shrugged and said she didnt know. After a few phone calls, I eventually just went to a different gate agent on the other side of the terminal and got the help I needed.

The TSA check in took 1.5 hours to get through in Austin and I missed my flights back to DC

As previously stated the delay I experienced flying from Wichita to Chicago caused a host of issues. When I finally was able to be booked on the last remaining American flight from Chicago to Cincinnati, the gate changed four times with the last change occurring very near the scheduled boarding time. While I didn't have a problem moving from gate to gate, I did notice and make note of others that had mobility issues and had to move each time for the gate change.

Overall, my last three trips on American Airlines have all been either delayed or "rescheduled" due to mechanical issues. At least on delay caused me to miss two possible connecting flights each later than the first. My last option for my last connection required the assistance of the onsite service desk (O'Hare Airport). The wait time for the service desk was such that it jeopardized getting booked on the last connecting flight available for the night. Suffice it to say, my latest experiences with American Airlines have caused me extensive loss of productive business and personal time and can therefore be classified as significantly less than satisfactory.

There was free WiFi (definitely a plus), but the flight was delayed 45 minutes waiting on a catering truck that never arrived. The pilot said there would be food vouchers given out at the end of the gangway to make up for the inconvenience, but there was no one offering those. Delay made me late for work!

Waiting for gate in RDU for more than 20mins is crazy.

Flight was on time and there was an empty seat next to me. That makes for a good flight!

Maintenance took a very long time and then we were in a holding pattern. While a one-off maintenance issue is standard, there were delays on both of my flights for this trip based on maintenance issues with the planes, which delayed both flights over 45 minutes. Thankfully, I didn't have any connections but it wasn't an experience that would make me pick AA if I have other options.

I like that the flight attendant was very attentive and helpful. The meal menu could have more of an variety of food choices.

Everything you need to know for your flight from Knoxville to La Crosse

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