TYS - LSE

$480 Find Cheap Flights from Knoxville to La Crosse

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to La Crosse departing on 1/7. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to La Crosse

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to La Crosse, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to La Crosse, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$480
American Airlines
Wed 1/7Sat 1/10
TYS - LSE • 1 stop
Cheapest one-way
Multiple Airlines
Sat 11/22
TYS - LSE • multi-stop
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to La Crosse!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Knoxville to La Crosse (TYS-LSE)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Knoxville to La Crosse that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to La Crosse

Wed, Jan 7 - Sat, Jan 10
American Airlines Logo
5:15 pm - 10:16 pmTYS-LSE
6h 01m1 stop
American Airlines Logo
5:08 pm - 10:09 pmLSE-TYS
4h 01m1 stop
$480American Airlines
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Wed, Jan 7 - Sat, Jan 10
American Airlines Logo
12:17 pm - 10:16 pmTYS-LSE
10h 59m2 stops
American Airlines Logo
5:08 pm - 10:09 pmLSE-TYS
4h 01m1 stop
$486American Airlines
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Wed, Jan 7 - Sat, Jan 10
American Airlines Logo
7:41 am - 4:16 pmTYS-LSE
9h 35m2 stops
American Airlines Logo
6:00 am - 3:20 pmLSE-TYS
8h 20m2 stops
$491American Airlines
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Booking Insights

KAYAK's insights & trends for Knoxville to La Crosse flights

Get data-powered insights and trends into flights from Knoxville to La Crosse to help you find the cheapest flights, the best time to fly and much more.

Which airlines fly non-stop between Knoxville and La Crosse?

Airline and price data is aggregated from results in KAYAK’s search results from the last 2 weeks for round-trip flights from Knoxville to La Crosse.

There is just one airline that flies from Knoxville to La Crosse direct and that is American Airlines. The best round-trip deal found from American Airlines for the route is $400.

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Good to know

Cheapest flight$480
Flight from Knoxville to La Crosse

When to book flights from Knoxville to La Crosse

Are your dates flexible? Find out the best times to travel from Knoxville to La Crosse based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Knoxville to La Crosse

  • What is the cheapest flight from Knoxville to La Crosse?

    In the last 3 days, the lowest price for a flight from Knoxville to La Crosse was $480 for a round-trip ticket.

  • Do I need a passport to fly between Knoxville and La Crosse?

    No

  • Which aircraft models fly most regularly from Knoxville to La Crosse?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Knoxville to La Crosse?

    oneworld is the only airline alliance operating flights between Knoxville and La Crosse.

  • How does KAYAK find such low prices on flights from Knoxville to La Crosse?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to La Crosse.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to La Crosse?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to La Crosse from Knoxville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to La Crosse?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to La Crosse with an airline and back to Knoxville with another airline. Booking your flights between Knoxville and LSE can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to La Crosse?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to La Crosse from Knoxville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Knoxville to La Crosse

 
See real verified KAYAK customer reviews for airlines flying from Knoxville to La Crosse. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Knoxville to La Crosse? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 11048 reviews
6.4Food
7.5Boarding
7.2Comfort
8.0Crew
6.9Entertainment
Airline reviews

We were told the flight was delayed 5 times, then it was moved to the next day.

2.0 MediocreAnonymous, Nov 2025DCA - LAX
Read more American Airlines reviews

We were told the flight was delayed 5 times, then it was moved to the next day.

More choices on snacks. Built-in video screen to enjoy entertainment choices.

we landed at cmh ten minutes early but had to sit on tarmac for twenty minutes because a plane was at our gate despite the fact that 3 other gates were open.

The experience with American Airlines was good, although the Philippines Airlines flight was much better (better seats, better food, better entertainment options, overall better). Again, the MIA to LAX flight was fine, but nothing in comparison to the comfort and accommodations of the Philippines Airlines flight from LAX to MNL.

I have a gluten allergy so did have any food

I have a gluten allergy so didn't have any food

Loved the crew . Absolutely no complaints. Except for luggage lost

Everything was good The connects, with no blame to crew. Or pilots. I understand they are short staffed. Everything went well for me. I'll be using you guys again in May if not sooner.

this plane was really old, had exit row seats and tray was in arm of seat so super uncomfortable to use. another seat they could t even use the tray it was broke. seat i. front of me had duct tape on it cause seat was ripped open... this plane should either be updated or retired.

Baggage handling poor. Second time this has happened. My bag went to San Francisco instead of Fiji. No apology. Luckily Nadi airport staff are fantastic. My bag arrived in Fiji the next day.

Everything you need to know for your flight from Knoxville to La Crosse

Information on your arrival and departure airports

Knoxville (TYS)
La Crosse (LSE)