$399 Find Cheap Flights from La Crosse to Missouri

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from La Crosse to Missouri departing on 6/20. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult

KAYAK searches hundreds of travel sites at once for deals on flights to Missouri

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from La Crosse to Missouri, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from La Crosse to Missouri, as well as popular online travel agencies
Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 22% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Flights Deals
Useful Info
Flights Deals

Best Missouri Flight Deals from La Crosse

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours

Kansas City
Kansas City1 stop$468
Columbia
Columbia1 stop$856
Kansas City
Kansas City1 stop$468
Columbia
Columbia1 stop$856

Cheap Flights from La Crosse to Missouri

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from La Crosse to Missouri that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.

Recent round-trip flight deals from La Crosse to Missouri

Recommended round-trip deals departing in the coming months from the most popular airlines that fly from La Crosse to Missouri.
Discover the best prices for you by selecting your travel dates on KAYAK.
American Airlines Logo
4:35 pm - 8:34 pmLSE-MCI
3h 59m1 stop
American Airlines Logo
5:07 pm - 11:30 pmMCI-LSE
6h 23m1 stop
$468American Airlines
Find Deal
Thu, Jun 26 - Mon, Jun 30
American Airlines Logo
11:13 am - 7:03 pmLSE-MCI
7h 50m2 stops
American Airlines Logo
7:40 pm - 11:30 pmMCI-LSE
3h 50m1 stop
$474American Airlines
Find Deal
Thu, Jun 26 - Mon, Jun 30
American Airlines Logo
11:13 am - 11:13 pmLSE-MCI
12h 00m2 stops
American Airlines Logo
5:25 am - 4:05 pmMCI-LSE
10h 40m2 stops
$505American Airlines
Find Deal
Thu, Jun 26 - Mon, Jun 30
American Airlines Logo
4:36 pm - 8:34 pmLSE-COU
3h 58m1 stop
American Airlines Logo
4:26 pm - 8:13 pmCOU-LSE
27h 47m1 stop
$856American Airlines
Find Deal
Mon, May 19 - Fri, May 23
American Airlines Logo
4:36 pm - 8:34 pmLSE-COU
3h 58m1 stop
American Airlines Logo
5:58 pm - 11:19 amCOU-LSE
17h 21m2 stops
$1,013American Airlines
Find Deal
Mon, May 19 - Fri, May 23
American Airlines Logo
4:36 pm - 11:41 amLSE-COU
19h 05m2 stops
American Airlines Logo
5:58 pm - 11:19 amCOU-LSE
17h 21m2 stops
$1,284American Airlines
Find Deal
Mon, May 19 - Fri, May 23
Useful Info

KAYAK's insights & trends for La Crosse to Missouri flights

Get data-powered insights and trends into flights from La Crosse to Missouri to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from La Crosse to Missouri?

The average price of all round-trip flights from La Crosse to Missouri clicked on KAYAK for each day over the last 12 months.

When flying from La Crosse to Missouri, you should consider leaving on a Wednesday and avoid Fridays if you are looking for the best rates. For your return to La Crosse, you’ll find the best rates on Fridays and the most expensive ones on Tuesdays.


Good to know

Cheapest flight$399
Flight from La Crosse to Kansas City

FAQs - booking Missouri flights

  • How does KAYAK find such low prices on flights from La Crosse to Missouri?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from La Crosse to Missouri.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from La Crosse to Missouri?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from La Crosse to Missouri is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from La Crosse to Missouri?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from La Crosse to Missouri with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from La Crosse to Missouri?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from La Crosse to Missouri up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to Missouri?

    The cheapest time of day to fly to Missouri is generally in the evening, when round-trip flights cost $392 on average. Morning departures are around 5% more expensive than evening flights, on average. The most expensive time of day to fly to Missouri is generally in the morning, which is peak travel time and where the average cost of a ticket is $410.

Top airline flying from La Crosse to Missouri

 
See real verified KAYAK customer reviews for airlines flying from La Crosse to Missouri. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from La Crosse to Missouri? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 10000 reviews
7.5Boarding
6.9Entertainment
6.5Food
8.0Crew
7.2Comfort
Airline reviews

The boarding was pretty easy. However, the first class seats are not lay flat as other airlines (like JetBlue) has and therefore sleeping was a challenge.

6.0 GoodBob, May 2025LAS - MIA
Read more American Airlines reviews

The boarding was pretty easy. However, the first class seats are not lay flat as other airlines (like JetBlue) has and therefore sleeping was a challenge.

It was nobody’s fault - but the plane came 4-hrs late and we were updated randomly in 20-30 mins increments which left us hostage to sit and wait expectantly. It was very long and got very late. Our plane didn’t land until nearly 1 am! Also the toilet wasn’t working. The hosts were nice enough but were clearly “about to pass out” as one told me. Lastly, there was no snack or even time for it. Just a bad experience overall.

In flight connectivity (via T-Mobile) was often not working.

Pitch was very small. Knees were on the seat back in front of me.

Several delays. Next flight was worse. Did not arrive home until 2am PT

Very helpful ground crew after an earlier flight delay and being rebooked on a different flight.

Everything about the flight was lovely…We left early, arrived early, cabin crew were efficient and helpful. Flight was easy and most pleasant.

First world problems, but still… We were seated in first class and asked for a cocktail on a very short, 50 minute flight. After our drink order was taken, a half hour went by, and we noticed that every other person in the small plane had been served except for us. We got up to ask about it, the drinks finally came, then were taken away three minutes later since the flight was so short. Really strange situation, on the other hand, we were in Utah.

We missed our flight. The boarding pass had the wrong gate and by the time we received the text from Kayak, our flight was already gone. I’ll never use Kayak again and will go direct to the airlines in the future.

Boarding took forever, the plane was cramped and cold, and the seatbelt song came on constantly throughout the red eye flight with a loud pre-recorded message playing each time

Everything you need to know for your flight from La Crosse to Missouri

Information on your arrival and departure airports

Not what you’re looking for? Find thousands of other hotels, flights, car rentals and package deals with KAYAK.