$295 Find Cheap Flights from Lexington to Panama

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Lexington to Panama departing on 9/5. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

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Cheap Flights from Lexington to Panama

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Panama City
Panama City2 stops$546
Panama City
Panama City2 stops$546

Book Cheap Lexington to Panama Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Lexington to Panama that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Lexington to Panama

Fri, Jan 23 - Tue, Jan 27
United Airlines Logo
7:30 am - 8:02 pmLEX-PTY
12h 32m2 stops
United Airlines Logo
11:35 am - 11:41 pmPTY-LEX
12h 06m2 stops
$546United Airlines
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Wed, Oct 1 - Sun, Oct 5
American Airlines Logo
6:34 pm - 2:31 pmLEX-PTY
20h 57m2 stops
American Airlines Logo
3:31 pm - 11:41 amPTY-LEX
19h 10m2 stops
$571American Airlines
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Fri, Jan 23 - Tue, Jan 27
Delta Logo
5:55 am - 2:02 pmLEX-PTY
8h 07m1 stop
Delta Logo
3:27 pm - 11:55 pmPTY-LEX
8h 28m1 stop
$581Delta
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Wed, Oct 1 - Wed, Oct 8
United Airlines Logo
7:33 pm - 2:14 pmLEX-PTY
19h 41m2 stops
United Airlines Logo
3:30 pm - 3:48 pmPTY-LEX
23h 18m2 stops
$586United Airlines
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Tue, Sep 23 - Sun, Sep 28
American Airlines Logo
12:39 pm - 12:55 pmLEX-PTY
25h 16m2 stops
American Airlines Logo
3:31 pm - 6:44 pmPTY-LEX
26h 13m2 stops
$591American Airlines
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Tue, Sep 23 - Sun, Sep 28
Delta Logo
6:00 am - 12:55 pmLEX-PTY
7h 55m1 stop
Delta Logo
2:10 pm - 11:47 pmPTY-LEX
8h 37m1 stop
$757Delta
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Tue, Sep 23 - Sun, Sep 28
 Logo
4:38 pm - 10:34 amLEX-PTY
18h 56m1 stop
 Logo
9:34 am - 7:44 pmPTY-LEX
33h 10m2 stops
$1,131
Find Deal
Sun, Dec 21 - Sat, Dec 27
United Airlines Logo
5:48 pm - 2:45 pmLEX-PTY
20h 57m2 stops
United Airlines Logo
4:41 pm - 1:16 pmPTY-LEX
20h 35m2 stops
$1,166United Airlines
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Wed, Oct 1 - Wed, Oct 8
 Logo
3:42 pm - 10:53 amLEX-PTY
20h 11m2 stops
 Logo
12:03 pm - 6:45 pmPTY-LEX
29h 42m1 stop
$1,189
Find Deal
Tue, Sep 23 - Sat, Sep 27
Avianca Logo
7:00 am - 4:30 pmLEX-PTY
34h 30m2 stops
Avianca Logo
3:20 am - 9:01 pmPTY-LEX
16h 41m2 stops
$1,338Avianca
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Booking Insights

KAYAK's insights & trends for Lexington to Panama flights

Get data-powered insights and trends into flights from Lexington to Panama to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Lexington to Panama?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Lexington to Panama were found on United Airlines ($546) and American Airlines ($571).

Good to know

Cheapest flight$295
Most popular time to fly and prices are also 11% lower on average.
Flight from Lexington to Panama City

FAQs - booking Panama flights

  • How does KAYAK find such low prices on flights from Lexington to Panama?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Lexington to Panama.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Lexington to Panama?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Lexington to Panama is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Lexington to Panama?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Lexington to Panama with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Lexington to Panama?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Lexington to Panama up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to Panama?

    The cheapest time of day to fly to Panama is generally at night, when round-trip flights cost $332 on average. Morning departures are around 22% cheaper than evening flights, on average. The most expensive time of day to fly to Panama is generally in the evening, which is peak travel time and where the average cost of a ticket is $573.

Reviews of the top airline flying from Lexington to Panama

 
Need help choosing which airline to fly with from Lexington to Panama? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 7981 reviews
7.3Food
8.2Boarding
7.9Comfort
8.5Crew
7.9Entertainment
Airline reviews

Three seats in first class were broken and while they were able to still acommodate us it was looking very touch and go and they had others they could not acommodate

6.0 GoodKristopher, Aug 2025HPN - ATL
Read more Delta reviews

Three seats in first class were broken and while they were able to still acommodate us it was looking very touch and go and they had others they could not acommodate

Mechanic delay in addition to a 2 hour change in takeoff time was frustrating.

Delayed due to thunderstorms and no in-flight service due to rough weather — both of which are out of Delta’s control. Flight was good overall.

The flight attendants in SLC were rude. I arrived 40 minutes early to gate. Ticket said I needed check in for seat assignments and tried check in and attendants said they weren’t doing it. And proceeded to never call me to give me a ticket so when time to board I received the very last seat. Please relay to employees to do their job better..,

On this flight I felt the food offering was not as complete as on previous flights. The tomato salad was a bit off and there was nothing additional such a bread or butter. The breakfast was only one option, so you either ate what they had or ate nothing. The crew was efficient, but most seemed frustrated throughout the flight. The flight arrived early and was obstacle-free, so I’m overall quite happy, but the shine in the rest of the experience just wasn’t there.

The seats got pretty uncomfortable pretty fast. The armrests are bigger than on other planes, so I had less room in the actual seat. My butt hurt by the end of the flight. :/ comfort was the primary issue. The crew were fantastic!

I believe that a four-hour trip should have a meal. Delta had none.

Great flight with Delta! Boarding was quick and easy, the amenities were solid, and the plane was in great shape. The flight attendants had a fun, lively energy while staying professional. All in all, a smooth trip — even managed to catch up on some rest. Thanks, Delta!

I was uncomfortably cold on the plane. Other than that it was uneventful and therefore as enjoyable as a plane ride can be.

There was supposed to be a meal served, but there wasn’t and the major toilet was out of order

Everything you need to know for your flight from Lexington to Panama

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