$248 Find Cheap Flights from Lexington to Panama

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Lexington to Panama departing on 4/29. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Flight Deals

Book Cheap Lexington to Panama Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Lexington to Panama that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Lexington to Panama

Fri, Jan 9 - Fri, Jan 16
American Airlines Logo
4:35 pm - 1:27 pmLEX-PTY
20h 52m2 stops
American Airlines Logo
4:50 pm - 3:37 pmPTY-LEX
22h 47m2 stops
$566American Airlines
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Mon, Feb 23 - Thu, Feb 26
United Airlines Logo
5:34 pm - 2:45 pmLEX-PTY
21h 11m2 stops
United Airlines Logo
4:41 pm - 4:50 pmPTY-LEX
24h 09m2 stops
$617United Airlines
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Sun, Dec 14 - Sun, Dec 21
United Airlines Logo
5:47 pm - 2:45 pmLEX-PTY
20h 58m2 stops
United Airlines Logo
11:35 am - 1:16 pmPTY-LEX
25h 41m2 stops
$626United Airlines
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Sat, Apr 4 - Sun, Apr 12
American Airlines Logo
5:50 pm - 12:40 pmLEX-PTY
19h 50m2 stops
American Airlines Logo
1:55 pm - 10:32 amPTY-LEX
19h 37m2 stops
$721American Airlines
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Mon, Feb 23 - Thu, Feb 26
Delta Logo
6:00 am - 1:55 pmLEX-PTY
7h 55m1 stop
Delta Logo
3:20 pm - 6:51 pmPTY-LEX
27h 31m1 stop
$756Delta
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Mon, Feb 23 - Thu, Feb 26
Delta Logo
6:00 am - 1:55 pmLEX-PTY
7h 55m1 stop
Delta Logo
3:20 pm - 6:51 pmPTY-LEX
27h 31m1 stop
$809Delta
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Wed, Dec 24 - Fri, Jan 9
American Airlines Logo
2:52 pm - 1:53 pmLEX-PTY
23h 01m2 stops
American Airlines Logo
4:50 pm - 2:11 pmPTY-LEX
21h 21m2 stops
$942American Airlines
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Thu, Dec 25 - Fri, Jan 9
American Airlines Logo
2:05 pm - 3:54 pmLEX-PTY
25h 49m2 stops
American Airlines Logo
4:50 pm - 2:11 pmPTY-LEX
21h 21m2 stops
$948American Airlines
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Sat, Apr 4 - Sun, Apr 12
American Airlines Logo
6:00 am - 12:40 pmLEX-PTY
7h 40m1 stop
American Airlines Logo
1:55 pm - 10:32 amPTY-LEX
19h 37m2 stops
$973American Airlines
Find Deal
Fri, Jan 9 - Fri, Jan 16
Delta Logo
6:00 am - 1:55 pmLEX-PTY
7h 55m1 stop
Delta Logo
3:20 pm - 11:51 pmPTY-LEX
8h 31m1 stop
$1,166Delta
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Booking Insights

KAYAK's insights & trends for Lexington to Panama flights

Get data-powered insights and trends into flights from Lexington to Panama to help you find the cheapest flights, the best time to fly and much more.

Which airlines fly non-stop between Lexington and Panama?

Airline and price data is aggregated from results in KAYAK’s search results from the last 2 weeks for round-trip flights from Lexington to Panama.

There is just one airline that flies from Lexington to Panama direct and that is Delta. The best round-trip deal found from Delta for the route is to Panama City (PTY) and costs $665.

Which airlines provide the cheapest flights from Lexington to Panama?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Lexington to Panama were found on American Airlines ($566) and United Airlines ($566).

Good to know

Low seasonFebruary
Cheapest flight$248
Best time to beat the crowds with an average 44% drop in price.
Most popular time to fly and prices are also 19% lower on average.
Flight from Lexington to Panama City

FAQs - booking Panama flights

  • How does KAYAK find such low prices on flights from Lexington to Panama?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Lexington to Panama.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Lexington to Panama?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Lexington to Panama is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Lexington to Panama?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Lexington to Panama with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Lexington to Panama?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Lexington to Panama up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to Panama?

    The cheapest time of day to fly to Panama is generally at night, when round-trip flights cost $332 on average. Morning departures are around 22% cheaper than evening flights, on average. The most expensive time of day to fly to Panama is generally in the evening, which is peak travel time and where the average cost of a ticket is $573.

Reviews of the top airline flying from Lexington to Panama

 
Need help choosing which airline to fly with from Lexington to Panama? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8003 reviews
8.5Crew
8.1Boarding
7.3Food
7.9Entertainment
7.9Comfort
Airline reviews

No lunch on a x-country flight scheduled for 10:50 am departure, arrived 5+ hrs later. That requires a black box label before you pay for the tickets. Worst, when I checked in online, it's specifically said that lunch was served on his flight for economy Plus passengers.

8.0 ExcellentDeborah, Nov 2025LAX - RDU
Read more Delta reviews

No lunch on a x-country flight scheduled for 10:50 am departure, arrived 5+ hrs later. That requires a black box label before you pay for the tickets. Worst, when I checked in online, it's specifically said that lunch was served on his flight for economy Plus passengers.

We had a lot of really rough weather but that was not Delta's fault. Pilot was amazing.

First, Delta needs more flights to/from Miami. Second, a 1000pm leaving at 1230pm is unacceptable from their biggest airport world hub. Another aircraft could have been used such as the aircraft scheduled to be used in the morning for that exact same route. Yes, I did get me there but the lack of sleep the next day didn't help me enjoy my entire trip since I was busy with activities during the weekend. This can be and is expected from Spirit (going bankrupt) and Frontier (despite they're nickel and dimers). But from Delta's World Hub? That's totally unacceptable!

This flight was straightforward and without difficulty. Service was OK, but I continue to be underwhelmed by level of attention given to Sky Priority passengers.

It would’ve been nice for all that money to have a more substantial snack for free. I remember once upon a time getting a very nice turkey sandwich with Swiss cheese on whole wheat bread for no charge along with a drink. I guess those days are gone. it’s a little insulting being given a cookie or a bag of baked chips Going forward I’ll just bring my own.

Great. Seamless. Check in agent at kiosk international was amazing and extremely helpful.

Our flight from SFO to MSP was right on time on 11/15/2025. No delays. As we approached MSP at about 8 pm, we circled in the air until 8:40 pm so I don't call that efficient for MSP. I think the captain should announce the delay and why. (as if we all don't know that we are just circling around the area, slowing down, speeding up, slowing down.) Thank you. Marilyn Fischer

Service in business class was not impressive. I ordered coffee with dinner and then watched other people get 2 refills before I got my 1 cup of coffee, and only after I pressed the attendant button overhead. Furthermore, the seats in the forward cabin need maintenance on this 737-800: the upholstery is detaching from the seat frame, at least on the backs of seats 1C, 1D.

Plenty of leg room, temperature was great and staff was excellent. Would do it more often.

The ticket agents in West Palm Beach on Friday afternoon Nov. 7th were incredible in getting us on an earlier plane to Atlanta during the government shutdown. Had the taken our original flight we would have missed our connection. She did this on her own, We didn't even have to ask, and she did it all with a smile and showing genuine concern that we would be taken care of. We are very grateful and thankful. We fly often, and now we will be sure to fly Delta.

Everything you need to know for your flight from Lexington to Panama

Information on your arrival and departure airports