$353 Find Cheap Flights from Lexington to Panama - Compare and Save

1 adult
1 adult, Economy, 0 bags

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Price, demand and travel trends for Lexington to Panama flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

What are the cheapest fares from Lexington to Panama right now?

The cheapest fare from Lexington to Panama in the last week was $632 round-trip, to Panama City Tocumen Intl (PTY).

Which airport in Panama is the cheapest to fly to from Lexington?

All flights from Lexington to Panama arrive at Panama City Tocumen Intl (PTY). On average, round-trip fares are around $892.

What’s the cheapest day to fly from Lexington to Panama?

Sunday tends to be the cheapest day to fly from Lexington to Panama, while Saturday is the most expensive. Fares run about 55% higher that day, based on the past 12 months of KAYAK data.

Key details for Lexington to Panama flights

Low season

October

Cheapest flight

$353
One-way flight from Lexington to Panama City

Your Lexington to Panama flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • Is now a good time to book a flight from Lexington to Panama?

    Yes. Fares from Lexington to Panama are low right now. As a rule of thumb, a round-trip under $765 (cheaper than most fares this year) is a good deal, so if you spot one at or below that, it's a good time to book.

  • How much should I budget for a flight from Lexington to Panama?

    Over the past 12 months, round-trip fares from Lexington to Panama have ranged from $765 to $1,183.

  • What are the main airports serving Panama?

    Flights to Panama all arrive at Panama City Tocumen Intl (PTY).

  • What airlines fly nonstop from Lexington to Panama?

    Based on the flight schedule for the next 3 months, no airline regularly operates nonstop flights from Lexington to Panama. However, Delta offers a one-stop option.

  • Which cabin classes are available on flights from Lexington to Panama?

    On flights from Lexington to Panama you can only book Economy Class.

  • What are some popular landmarks in Panama?

    KAYAK travelers' favorite landmarks in Panama include:

    • ATLAPA Conventions Center
    • Panama Old Cathedral
    • Veneto Casino
    • Ancon Hill

Your guide to booking Lexington to Panama flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your travel dates are flexible, book your trip for August when flights are typically cheapest and avoid April when prices are at their highest.
  • Flying on Sunday is usually the cheapest. Flights on Saturday cost about 55% more on average, so being flexible with your travel dates could help you save.
  • Start your trip in Panama City, which is the most popular destination in Panama. From there, it's easy to continue on to other popular destinations such as Bocas del Toro, Río Hato and Boquete.

Reviews of the top airline flying from Lexington to Panama

 
Need help choosing which airline to fly with from Lexington to Panama? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
DeltaOverall score based on 8653 reviews
7.8Entertainment
7.8Comfort
8.1Boarding
8.5Crew
7.2Food
Airline reviews

Had to deplane 2 x due to problems with plane. Delayed over 6 hours ans was given a $12 food credit which barely oaud for anything and limited to wear incoukd redeem.

2.0 Mediocrenichole, Oct 2026
Read more Delta reviews

Had to deplane 2 x due to problems with plane. Delayed over 6 hours ans was given a $12 food credit which barely oaud for anything and limited to wear incoukd redeem.

After boarding the plane had to wait an hour at the for the copilot to show up before we could depart

No beverage/snack service without any explanation or reason. Late boarding and delayed flight.

more room in seats, larger snacks, more comms with delays

There was overbooking that delayed boarding. Then an airport emergency lockdown that caused further delays in boarding. However the time was made up during flight and there was a minimal delay in landing. Everything else was excellent.

No snacks not been water was offered I fly weekly and have to select Economy or extra comfort per business rules but will choose American at least they offer mid seat class passengers water. on short flights. The WIFI was awful on the plane as well. The thing I can not figure out is why you treat business class people this way we spend more money that your one trip first class passengers cumulative than others maybe look at the company name of the people flying and treat us better as there are thousands of us flying weekly and choose what airline we want to select.

The boarding agent guy in Lexington on 7/23 that boarded the flights to Atlanta is very rude for working in customer service. I know there were delays but he was dismissive rude and arrogant. Most native Kentucky residents are nice and very cordial he needs to eat a big ole piece of humble pie. I watched him be rude to several people and as much as he could of filled up a delayed flight to save you money and he was so rude to people it was ridiculous. Next no water or snacks on short flights is awful 1st you delay a flight then do not even offer water on the flight.. No thanks I like delta better but I travel ever week and to be treated like this might as well fly American at least they offer water and have better rewards.

The staff was fine. The plane was extremely tight, and I paid for the wifi and it did not work at all. I was actually going to ask for a refund.

Left on time and arrived early this extending our 31 minute transfer. Bags made it also!

The crew was very polite as I have a few handicaps and everything was made pleasant. Check-in was easy as I was brought on board by the wheelchair assistant. One flight attendant did make sure my personal item was carefully stored under the seat in front of me. I was made to feel welcome as a customer as I made my first trip with a few disabilities. Entertainment and wifi worked quite well. The only food service were snacks and drinks. Those were okay. Overall it was a very smooth flight and encouraged me to use Delta again.

More options for your flight from Lexington to Panama

Complete your trip to Panama with a hotel stay or car rental