$65 Find Cheap Flights from Louisville to South Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Louisville to South Carolina departing on 5/8. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to South Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Louisville to South Carolina.
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Louisville to South Carolina.
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Flight Deals

Cheap Flights from Louisville to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Charleston
Charlestonnonstop$135
Myrtle Beach
Myrtle Beachnonstop$109
Greenville
Greenville1 stop$281
Columbia
Columbia1 stop$289
Florence
Florence1 stop$481
Charlotte
Charlotte1 stop$209
Charleston
Charlestonnonstop$135
Myrtle Beach
Myrtle Beachnonstop$109
Greenville
Greenville1 stop$281
Columbia
Columbia1 stop$289
Florence
Florence1 stop$481
Charlotte
Charlotte1 stop$209

Book Cheap Louisville to South Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Louisville to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Louisville to South Carolina

Sun, Jun 21 - Thu, Jun 25
Allegiant Air Logo
5:10 pm - 6:41 pm
SDF
-
SAV
1h 31mnonstop
Allegiant Air Logo
11:20 am - 12:59 pm
SAV
-
SDF
1h 39mnonstop
$105Allegiant Air
Sun, Jun 7 - Sun, Jun 14
Allegiant Air Logo
8:56 pm - 10:27 pm
SDF
-
SAV
1h 31mnonstop
Allegiant Air Logo
8:45 am - 10:24 am
SAV
-
SDF
1h 39mnonstop
$107Allegiant Air
Fri, May 8 - Mon, May 11
Breeze Airways Logo
8:28 pm - 10:06 pm
SDF
-
CHS
1h 38mnonstop
Breeze Airways Logo
7:00 am - 8:46 am
CHS
-
SDF
1h 46mnonstop
$135Breeze Airways
Fri, Jun 12 - Mon, Jun 15
Breeze Airways Logo
8:28 pm - 10:06 pm
SDF
-
CHS
1h 38mnonstop
Breeze Airways Logo
7:00 am - 8:46 am
CHS
-
SDF
1h 46mnonstop
$141Breeze Airways
Tue, Apr 14 - Thu, Apr 16
Spirit Airlines Logo
12:42 pm - 5:33 pm
SDF
-
MYR
4h 51m
1 stop
Spirit Airlines Logo
11:52 am - 5:04 pm
MYR
-
SDF
5h 12m
1 stop
$172Spirit Airlines
Sat, Apr 18 - Sat, Apr 25
Spirit Airlines Logo
6:06 pm - 11:29 pm
SDF
-
MYR
5h 23m
1 stop
Spirit Airlines Logo
11:52 am - 5:04 pm
MYR
-
SDF
5h 12m
1 stop
$219Spirit Airlines
Sat, Apr 11 - Tue, Apr 14
American Airlines Logo
9:54 am - 3:40 pm
SDF
-
HHH
5h 46m
1 stop
American Airlines Logo
5:51 pm - 11:30 pm
HHH
-
SDF
5h 39m
1 stop
$289American Airlines
Sat, Apr 25 - Mon, May 4
Delta Logo
8:10 am - 1:14 pm
SDF
-
CAE
5h 04m
1 stop
Delta Logo
7:12 pm - 10:50 pm
CAE
-
SDF
3h 38m
1 stop
$289Delta
Sat, Apr 11 - Tue, Apr 14
American Airlines Logo
9:54 am - 3:40 pm
SDF
-
HHH
5h 46m
1 stop
American Airlines Logo
2:54 pm - 11:48 pm
HHH
-
SDF
8h 54m
2 stops
$294American Airlines
Wed, Apr 22 - Sun, Apr 26
Delta Logo
7:05 am - 1:14 pm
SDF
-
CAE
6h 09m
1 stop
Delta Logo
5:47 pm - 11:59 pm
CAE
-
SDF
6h 12m
1 stop
$314Delta
Booking Insights

KAYAK's insights & trends for Louisville to South Carolina flights

Get data-powered insights and trends into flights from Louisville to South Carolina to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest Louisville to South Carolina flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to South Carolina from Louisville found in the last 72 hours was to Myrtle Beach, at $69 round-trip. The most popular route is from Louisville (SDF) to Myrtle Beach (MYR), and the cheapest round-trip airline ticket found on this route in the last 72 hours was $69.

What is the cheapest time of day to fly to South Carolina?

The average price for all round-trip flights from Louisville to South Carolina depending on the time of departure, clicked by users on KAYAK in the last 2 weeks.

The cheapest time of day to fly to South Carolina is generally at night, when round-trip flights cost $133 on average. The most expensive time of day to fly to South Carolina is generally in the afternoon, which is peak travel time and where the average cost of a ticket is $204.

Can I save money by flying with a layover from Louisville to South Carolina?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $366, prices are generally cheapest when you fly direct.

What is the cheapest month to fly from Louisville to South Carolina?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Louisville to South Carolina, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Louisville to South Carolina is September, when tickets cost $156 (return) on average. On the other hand, the most expensive months are March and April, when the average cost of round-trip tickets is $365 and $356 respectively.

What’s the cheapest day of the week to fly from Louisville to South Carolina?

The average price of all round-trip flights from Louisville to South Carolina clicked on KAYAK for each day over the last 12 months.

If you are looking for a flight deal from Louisville to South Carolina, look for departures on Fridays and avoid leaving on a Wednesday, as it's usually the priciest day. When flying back from South Carolina, Thursday is the cheapest day to fly and Friday is the most expensive.

How far in advance should I book a flight from Louisville to South Carolina?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Louisville to South Carolina, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Louisville to South Carolina, you should book around 1 week before departure. For the absolute cheapest price, our data suggests you should book 21 weeks before departure.

Good to know

Low seasonJanuary
Cheapest flight$65
Best time to beat the crowds but there is an average 8% increase in price.
Most popular time to fly and prices are also 11% lower on average.
Flight from Louisville to Charleston

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Louisville to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Louisville to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Louisville to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Louisville to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Louisville to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Louisville to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Louisville to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Louisville to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Top tips for finding cheap flights to South Carolina

  • Looking for a cheap flight? 25% of our users found tickets from Louisville to the following destinations at these prices or less: Charlotte $175 one-way - $368 round-trip

Reviews of the top 5 airlines serving from Louisville to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Louisville to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Louisville to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.1
Breeze AirwaysOverall score based on 271 reviews
8.7Crew
6.6Food
8.2Comfort
6.6Entertainment
8.3Boarding
Airline reviews

Our flight was delayed 7 hours. Due to a change in equipment we were downgraded from "Nicest" to "Nicer," even having to pay for a soft drink. Disappointing. To Breeze's credit that issued a $100 flight credit. A refund would have been more appreciated.

6.0 GoodJames, Feb 2026
RDU - RSW
Read more Breeze Airways reviews

Our flight was delayed 7 hours. Due to a change in equipment we were downgraded from "Nicest" to "Nicer," even having to pay for a soft drink. Disappointing. To Breeze's credit that issued a $100 flight credit. A refund would have been more appreciated.

Lost my luggage and terrible experience with customer service trying to track it down

10 hour delay with minimal updates. Couldn’t leave terminal and then ended up on redeye with a dirty broken plane. It is literally impossible to reach customer service via gate agent, app, phone, text or email.

I thought that I had pre-purchased carry-on luggage and was surprised when I tried to check in that I did not have it.

Flight departure was 90 min delayed, and the boarding experience was confused, stressful, and generally poor. Additionally, the wifi on the plane was malfunctioning for all but the final 15 min of the flight into ILM.

Great experience and In love flying in and out of Provo airport

You get what you pay for. It’s like a bus but flying. No frills, no snacks. Leg room was fine, boarding was good.

Overall good. Plenty of legroom and fairly comfortable seats. No issues with capacity and the overhead been even though most people brought several carry-ons on. I don’t think Breeze really enforces the pay for a carry-on rule.

Surprised at how much I enjoyed Breeze. Paid for the Nicer upgrade which made it closer in price to a flag ship carrier but with more comfortable seats and much more leg room. Crew was polite and since we brought our food no loss there. Would make the point that the ‘have to pay for a carry-on is BS’. Most people did not and had several. Still was plenty of room in the overheads.

Comfortable seating, adequate space available, nice to have USB port, polite crew.

First class is comfortable. Enjoyed a movie and was able to relax compared to coach.

Loved flying First Class. Very comfortable. The seat was amazing. Enjoyed a movie and was able to relax so much better than in coach.

We landed and sat on the tarmac for 45 minutes because they only have one gate at the airport and there was another plane running late so we had to wait

The WiFi was not working. That made for a long flight.

Absolutely no communication on why there's a delay and multiple flight time reschedules. I would have canceled the flight and drove back home if I known it was going to be rescheduled 3 or 4 times.

Another late night flight and MORE men belligerently drinking and yelling. I had to move from first to economy because they were so obnoxious and disruptive. Crazy to go from a cozy chair to cardboard when you were supposed to be in first. Delta allows was too much drinking which leads to belligerent behavior.

I was in first class and literally the men behind me were so aggressively loud I moved myself to economy. This has become so common on Delta - people using audio without headphones, and men on 12am / late night flights drinking and yelling to talk to each other which prevents anyone around them from resting. Pretty crazy to have to move from first to economy (poorer service, less comfort...). Wild wild. Looking into other airlines.

Love delta smaller commuter plane so no entertainment and paid wifi on MKE-LGA leg was extremely unreliable and slow

Stop changing gates. Stop cancelling flights Stop moving my seat.

Extremely disappointed with Delta. They canceled flight last minute and then I rebooked the other flights and with which were delayed as well

Superb. Staff great. Great flight. As with other airlines, seating too tight and restrictive.

There is not one likable thing about this airline. It’s starts with the deceptive pricing and continues through the whole flight. The worst staff I’ve ever experienced way over priced bags absolutely no food or drink (unacceptable and you should be embarrassed) the seats are cramped and uncomfortable there is no entertainment there is nothing about this trash airline that constitutes any amount of money. It’s worse than spirit and way more expensive it is disgraceful. Do not travel with Allegiant I repeat do not bother no matter what they say the price is it is never ever going to be the right choice I’m mind blown at how awful the entire experience was I’m embarrassed that I chose so poorly I cannot reiterate enough how beyond horrible this company and its staff are, not one person on this flight or at the airport is qualified to sweep up trash on a city sidewalk they should certainly never be given any job that requires a brain or manners or communication with human beings, what a disgrace to the human race. Your criminal chiselers and should be put out to pasture

Great flight. Friendly staff. Free snacks and drinks would be nice. I would love fewer taxes and fees added on.

My 90 year old father flew with me. He needed wheel chair assistance and is nearly deaf. The staff was amazing with him.

It was fine. Nobody was outstandingly friendly but no one was rude and everything was smooth . The captain thanked us for flying but no one greeted me as I walked on the plane or as I exited which is the least they could do lol

Clean, friendly, roomy. But check-in from the phone link was terrible. Repeated attempts wouldn’t save at the final step. Just kept spinning! It was very frustrating. Finally, I used the app (vs website link) to check-in which worked very smoothly on the first attempt.

Check in on the web portal was cumbersome! After several attempts I finally got the boarding pass.

Excellent flight and even arrived 23 min early. No entertainment , or wi fi on board, but I downloaded a couple of movies beforehand which kept me entertained. Really like flying Allegiant airlines.

WE were delayed about an hour and never any communications from the employees working the gate. We also were moved to a total of three gates.

I love how they show love to their customers and care about them too.

Delay after delay with little communication then AA lost my luggage and at airport would not assist just said scan this QR code to track your luggage and submit a claim. However QR code provided did not work so have to go back to airport

After changing the departure gate 5 times making us mo e from one side of the airport to the other and then back the flight was delayed nearly 2 hours. The male flight attendant had a bad attitude with the guest being condescending, disrespectful with people who were already on edge.

Easy boarding. Rows are smaller but that may be an older and bigger me now :)

It would have been nice if American tried to care.

American Airlines did everything they could with the high Spring Break crowd. I was frustrated to be changed from 1st class to a middle seat at the back of the plane. This has happened before, not sure booking 1st class and paying the extra actually works.

I booked 1st class, my flights were changed and I was sitting in the middle at the back of the plane. A far cry from the 1st class I purchased for my flights. I am grateful I arrived on time.

There was no beverage service and the only time I saw a crew member walk through the cabin is when we were preparing to land.

Our flight was delayed 3 times and this is why I am giving such low reviews. Everything else was okay but being in the airport at 4:30pm for my initial flight at 7pm to not leave until after 9:30pm is insane,

Flights were constantly delayed. CRW took 50 minutes to get bags

Flight has been delayed every time I've ever taken it. Seats uncomfortable. Children behind me yelling the entire flight. Some of this is out of their control but overall just consistently not a great experience.

My flight was ultimately cancelled but the lack of updates and professionalism from the crew leading up to the cancellation announcement was frustrating for all passengers.

Delay due to personnel issues on Spirit’s end. Original departure time 9:30pm. Took off at 2:15am. Lost an entire night’s sleep bc Spirit couldn’t get a crew together. Very poor.

Sadly the flight was delayed by 4 hours due to the weather snd sir traffic control staffing. Otherwise the crew was amazing and the flight was perfect.

If there are delays, it takes less than a minute for a Spirit employee to make an announcement. It’s very simple.

I’m still waiting to get on the flight. No one knows what’s happening. The passengers have gotten no updates. We have been up all night and waiting at the airport. This is no way to operate and we should be refunded for this lack of respect for their passengers.

The plane was clean and crew was nice. Can’t speak on food as I did not have any

Flight was delayed, then undelayed, then delayed again. Gate was changed to the other side of the airport. Horrible seats with no screens. Spirit os truly awful, even for a budget option.

flight delayed because of poor staffing and organization - confusion from gate agents and flight attendant supervisors scheduling a missing flight attendant. flight delay 1 hr 30 min

I liked the quickness of the boarding process. Things were run smoothly and the staff was very professional. The overall experience was great.

Flight was delayed more than 3 hours, and the metro had stopped running by the time we got to the terminal well past midnight, so I was stranded, alone, with no way to get home until the metro started up the next morning.

Everything you need to know for your flight from Louisville to South Carolina

Information on your arrival and departure airports