$41 Find Cheap Flights from Louisville to South Carolina - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Louisville to South Carolina departing on 8/8. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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Cheap Flights from Louisville to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Charleston
Charlestonnonstop$97
Myrtle Beach
Myrtle Beachnonstop$195
Greenville
Greenville1 stop$226
Columbia
Columbia1 stop$281
Florence
Florence1 stop$558
Charlotte
Charlotte1 stop$289
Charleston
Charlestonnonstop$97
Myrtle Beach
Myrtle Beachnonstop$195
Greenville
Greenville1 stop$226
Columbia
Columbia1 stop$281
Florence
Florence1 stop$558
Charlotte
Charlotte1 stop$289

Book Cheap Louisville to South Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Louisville to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Louisville to South Carolina

Fri, Sep 18 - Mon, Sep 21
Breeze Airways Logo
7:59 pm - 9:34 pm
SDF
-
CHS
1h 35mnonstop
Breeze Airways Logo
6:10 am - 8:02 am
CHS
-
SDF
1h 52mnonstop
$97Breeze Airways
Fri, Aug 28 - Mon, Aug 31
Breeze Airways Logo
8:28 pm - 10:06 pm
SDF
-
CHS
1h 38mnonstop
Breeze Airways Logo
7:00 am - 8:46 am
CHS
-
SDF
1h 46mnonstop
$98Breeze Airways
Thu, Aug 13 - Sun, Aug 16
Allegiant Air Logo
8:45 pm - 10:19 pm
SDF
-
SAV
1h 34mnonstop
Allegiant Air Logo
6:16 pm - 7:55 pm
SAV
-
SDF
1h 39mnonstop
$104Allegiant Air
Thu, Aug 13 - Sun, Aug 16
Allegiant Air Logo
8:45 pm - 10:19 pm
SDF
-
SAV
1h 34mnonstop
Allegiant Air Logo
6:16 pm - 7:55 pm
SAV
-
SDF
1h 39mnonstop
$114Allegiant Air
Sun, Aug 16 - Thu, Aug 20
Multiple Airlines Logo
8:45 pm - 10:19 pm
SDF
-
SAV
1h 34mnonstop
Multiple Airlines Logo
10:05 am - 9:49 am
SAV
-
SDF
23h 44m
1 stop
$154Multiple Airlines
Fri, Aug 28 - Sun, Aug 30
Multiple Airlines Logo
8:28 pm - 10:06 pm
SDF
-
CHS
1h 38mnonstop
Multiple Airlines Logo
7:47 pm - 10:29 am
CHS
-
SDF
14h 42m
1 stop
$184Multiple Airlines
Fri, Aug 14 - Mon, Aug 17
American Airlines Logo
6:28 am - 11:33 am
SDF
-
CHS
5h 05m
1 stop
American Airlines Logo
6:15 am - 10:18 am
CHS
-
SDF
4h 03m
1 stop
$237American Airlines
Fri, Aug 28 - Mon, Aug 31
American Airlines Logo
11:10 am - 3:37 pm
SDF
-
CHS
4h 27m
1 stop
American Airlines Logo
2:06 pm - 5:59 pm
CHS
-
SDF
3h 53m
1 stop
$237American Airlines
Fri, Nov 6 - Mon, Nov 9
Southwest Logo
12:05 pm - 7:15 pm
SDF
-
CHS
7h 10m
1 stop
Southwest Logo
7:55 pm - 12:20 am
CHS
-
SDF
4h 25m
1 stop
$237Southwest
Mon, Oct 19 - Fri, Oct 23
Southwest Logo
6:15 pm - 9:30 pm
SDF
-
CHS
3h 15m
1 stop
Southwest Logo
6:35 am - 12:15 pm
CHS
-
SDF
5h 40m
1 stop
$237Southwest
Booking Insights

KAYAK's insights & trends for Louisville to South Carolina flights

Get data-powered insights and trends into flights from Louisville to South Carolina to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Louisville to South Carolina?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Louisville to South Carolina departing in September.

Flight prices are below average for this route right now.

Flights to South Carolina from Louisville usually cost between $118 and $394 in September.
The lowest price found in the past 5 days was $97 on Breeze Airways (Sep 18-Sep 21).

What is the cheapest Louisville to South Carolina flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to South Carolina from Louisville found in the last 5 days was to Myrtle Beach, at $46 round-trip. The most popular route is from Louisville (SDF) to Myrtle Beach (MYR), and the cheapest round-trip airline ticket found on this route in the last 5 days was $46.

What is the cheapest time of day to fly to South Carolina?

The average price for all round-trip flights from Louisville to South Carolina depending on the time of departure, clicked by users on KAYAK in the last 2 weeks.

The cheapest time of day to fly to South Carolina is generally at night, when round-trip flights cost $151 on average. The most expensive time of day to fly to South Carolina is generally at night, which is peak travel time and where the average cost of a ticket is $151.

Can I save money by flying with a layover from Louisville to South Carolina?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $303, prices are generally cheapest when you fly direct.

What is the cheapest month to fly from Louisville to South Carolina?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Louisville to South Carolina, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Louisville to South Carolina is September, when tickets cost $228 (return) on average. On the other hand, the most expensive months are April and March, when the average cost of round-trip tickets is $406 and $403 respectively.

What’s the cheapest day of the week to fly from Louisville to South Carolina?

The average price of all round-trip flights from Louisville to South Carolina clicked on KAYAK for each day over the last 12 months.

If you are looking for a flight deal from Louisville to South Carolina, look for departures on Mondays and avoid leaving on a Friday, as it's usually the priciest day. When flying back from South Carolina, Wednesday is the cheapest day to fly and Friday is the most expensive.

How far in advance should I book a flight from Louisville to South Carolina?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Louisville to South Carolina, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Louisville to South Carolina, you should book around 1 week before departure. For the absolute cheapest price, our data suggests you should book 24 weeks before departure.

Good to know

Low season

January

Cheapest flight

$41
Best time to beat the crowds with an average 4% drop in price.
Most popular time to fly and prices are also 1% lower on average.
Flight from Louisville to Myrtle Beach

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Louisville to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Louisville to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Louisville to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Louisville to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Louisville to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Louisville to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Louisville to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Louisville to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • How many flights are there between Louisville and South Carolina per day?

    There is a maximum of 1 nonstop flight a day that takes off from Louisville and lands in South Carolina, with an average flight time of 1h 35m. The most common departure time is 8:00 pm and most flights take off in the evening. Each week, there are 3 flights.

Top tips for finding cheap flights to South Carolina

  • Looking for a cheap flight? 25% of our users found tickets from Louisville to the following destinations at these prices or less: Charlotte $208 one-way - $349 round-trip

Reviews of the top 5 airlines serving from Louisville to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Louisville to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Louisville to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.2
Breeze AirwaysOverall score based on 304 reviews
6.7Food
6.7Entertainment
8.7Crew
8.3Boarding
8.2Comfort
Airline reviews

Flying with this airline is a true nightmare. We got delayed than stranded on layovers due to maintenance issues both ways of our flight and there’s no way to communicate with anyone other than AI bots that are absolutely useless. Never again.

2.0 MediocreAnonymous, Jul 2026
HVN - MSY
Read more Breeze Airways reviews

Flying with this airline is a true nightmare. We got delayed than stranded on layovers due to maintenance issues both ways of our flight and there’s no way to communicate with anyone other than AI bots that are absolutely useless. Never again.

Flight was great except for lunatic lady and her mother sitting middle/window who went nuts when the woman on the aisle wouldn’t stand up right away to let them out even though the aisle was full. Police had to be called. Some people just shouldn’t be allowed to fly.

You get what you pay for. It’s like a bus but flying. No frills, no snacks. Leg room was fine, boarding was good.

This was my first experience with Breeze. The plane was cleaner and more comfortable than any other I've experienced. The process of boarding was streamlined. We boarded early and arrived at our destination 45 minutes early. The only hiccup was my ticket was rejected by TSA PreCheck and I got sent to the back of a very long line at Fort Myers. I entered my information when I bought my ticket, but it apparently didn't connect to my permanent profile. I'll correct that for next time. I was expecting an Allegiant experience, but Breeze was much more upscale. I really, really enjoyed it.

Ridiculous to have to pay for carry on and to pick seats

Head rest did not move, very uncomfortable. Staff was great. There was no entertainment, would be nice not to have to pay for snack.

This is one of the worst trips that I have ever had. Ending up with an overnight delay. I’m not happy with the fact that they did not provide and set up the arrangement needed for lodging that we had to do it on our own. I also feel there should’ve been Compensation for food.

I like that the price is right! The airplane is clean and the staff is friendly. We landed safely, so that is always a gold star in my book! Great job!

Communication with airline electronically was difficult. No number seemed available to talk to customer service.

The price is amazing. I was worried about how the flight would be as I never flew then. Seats were very comfortable. We had lots of legroom. The Akron airport was really nice. Overall it didn't have the stress we usually experience with flying. Highly recommend

Boarding process of asking for volunteers to check bags goes against the system you had before with 2 bags checked free. This process is more of a guilt trip than a caring attitude toward the customer. In addition bag-size scrutiny has increased which also slows down the process of boarding. My wife said she will not fly on your airline again unless there is no other option.

Eveeyrime I fly they are begging for bags due to cabin overhead space. What they should so ia take the bags that are clearly too big to fit wheels first on their side. And those of us who give up the bag should really get their bags first. When boarding, nobody wants stupid jokes about how hot it is on board. Give us some cool air. Im usually sick from the heat by the time we take off.

No wifi, seems to be very common with Southwest currently. Everything else was normal.

Poor customer service, no accommodation for passengers when the flight was delayed over 5 hours.

Friendly crew kept coming by to make sure all was ok, provide additional refreshments, etc.

It was good. Last flight was delayed but I always say that is in God's plan

Red eye from San Diego. Temperature of the cabin was way too warm and the air duct flowed very little air.

Overall good, just screaming kids in the area the whole flight.

I'm glad it wasn't only 75% full because I could get a good seat

Check-in, Boarding and flight were smooth. All the employees and crew was very nice and funny. They gave the kids crayons and workbooks to keep them occupied which was a big win. I’ve flown Southwest many times and that’s the first time I’ve seen that and it is a great addition.

Flight was delayed before take off and at landing. Baggage took 20 minutes. Flight crew would not serve full soft drink and had to ask multiple times before receiving water.

For some reason, TSA Atlanta didn’t have my bag on the flight on time and they don’t have to provide Delta a reason for that.

I am still at the Airport! Delayed Delayed and Delyaed

The staff was fine. The plane was extremely tight, and I paid for the wifi and it did not work at all. I was actually going to ask for a refund.

The landing was the worst I’ve experienced with a flight.

It was last minute due to weather - considering - it was amazing! Good smiles, friendly staff and they were making sure we knew what was going on when and where.

Left on time and arrived early this extending our 31 minute transfer. Bags made it also!

The crew was very polite as I have a few handicaps and everything was made pleasant. Check-in was easy as I was brought on board by the wheelchair assistant. One flight attendant did make sure my personal item was carefully stored under the seat in front of me. I was made to feel welcome as a customer as I made my first trip with a few disabilities. Entertainment and wifi worked quite well. The only food service were snacks and drinks. Those were okay. Overall it was a very smooth flight and encouraged me to use Delta again.

All good on Delta's part. Passengers could be a little more courteous to each other.

The pilots were good. Disappointing when planes don't have electrical ports

It was poor a four hour delay and no explanation for the delay. What’s a 35 dollars going to do. It also made me miss my car rental,

It was on time. Flight was comfortable. Staff was nice. It was the way a flight should always be.

The price was the only good thing about this flight. It was scary during takeoff when the plane tilted side to side. It made me feel very nervous as I have never had a take-off that unsmooth. There was no on-flight movie or music options and the only complimentary option was water. Other airlines offer trail mix or a caramel cookie and pop options as complimentary. This flight was a 2.5 hour flight. I understand for shorter flights not having options, but a flight 2 hours or longer should offer more complimentary options and in flight entertainment. Also the seats did not recline and for a longer flight reclining seats are a must for comfort.

A very pleasant flight but it would be greatly improved with wifi to help entertain kids

This is a no frills, get it done, efficient airline. The seat is a lawn chair. You better bring your own entertainment. If you want something other than water you need to pay for it. But they will get you to your destination quickly, on time, and then they will turn the flight around and go right back where they came from. Reliably. Couple times a week tops. If it fits into your schedule, you can’t get there cheaper or faster.

A three hour delay to board and then another hour on the tarmac because they couldn't get a tractor? Ugh.

Allegiant canceled the flight. The flight the next day was full. Allegiant did not provide any compensation besides a refund. Last time on Allegiant.

Seats were very uncomfortable and being charged for snacks and water.........

It was canceled. The flight wasn’t rescheduled, everyone had to figure out their own new arrangements. They said we would get refunded our original fare and receive an additional $150. We received links for $100 only and they expired before we could activate them.

No frills, value airline. This trip was exactly what I expected. The flight was on time departing and arrived ahead of schedule. The crew was very efficient at getting people on and off the plane. I think the carry-on bag charges discouraged most people from bringing one, which led to quicker de-planing. I was careful to only bring a carefully packed personal item that was under the size limit. If you keep in mind that everything costs extra with this airline (including snacks, drinks, and printing boarding passes), and go into this with the right expectations, then all will be well. For the price difference, I would fly this airline again. My flight was only 1 hr. 20 minutes though. Much longer than that and comfort might drive me to another airline. The seats are very basic and don't recline at all.

Very turbulent flight, no drinks, very little service, unorganized boarding, gate changed multiple times

Flight had mechanical issues and it was delayed 30 mins - some of us boarded and then had to deplane.

Poor seat in rear of aircraft Food at Admiral’s Club Terminal D at DFW inedible

The AA app really sucks ... Every flight & connecting flights were delayed over 30 mins. One connecting flight on American Eagle said it was delayed in its arrival ... when it was actually parked across from the gate for over 1 hr before they pulled it to the gate. Seats in the economy/ main cabin are packed together like sardines ... no leg room.

To start, I’d like to say that every American Airline personnel I interacted with on the ground, especially flight crew, was very friendly and did their best to help me out. Despite this, however, my experience with the airline was an entire mess. The 7:19 PM flight was heavily delayed due to weather, and pushed to 10:30 AM the next morning. Because of this, I had to spend the night inside of the airport. At some point later in the night, I got an email saying that the flight had been canceled. I called the support number, and the representative on the other line told me that the flight was still on and that I didn’t need to rebook. The next morning, no one came to the gate to open the door for the crew until almost 11 AM. By this time the flight crew had been waiting for over an hour, and they had called management to get someone to open the door for them multiple times. Around 11:30, the gate screen had changed to a different flight. I ended up buying a last minute ticket with Southwest airline just to get to Chicago, because the next flight with American wasn’t until 7:19 pm that day. Now, earlier that morning my suitcase had been sent ahead of me to ORD. I went to baggage claim to ask them if I could have my suitcase forwarded to where I was staying. The representative at SDF baggage claim said they could and put the claim in for me. As I was going back through TSA, I got an email that the airline had found my suitcase, but the next step was to send it BACK to SDF. I called the airline support number again, and I made it clear that my suitcase needed to stay in Chicago and to not come back to SDF. The representative told me that they would hold my suitcase at ORD and that it wasn’t going to be forwarded anywhere. Once I got there, I found that they had loaded my suitcase onto a plane to send it back to SDF. Thankfully, I had gotten to the baggage claim counter in time for them to put in a request to bring my suitcase back up. My refund with the airline is processing already, but because of this entire experience and miscommunication at every turn of the way, I will not book with American Airlines in the future.

Cabin was roomy enough to easily slide my carry on under the seat in front of me!

Multiple gate changes and significant delay leaving DFW. Made for a late arrival

They needed to de-ice the plane. Apparently airlines have a problem keeping their de-icing vehicles in good repair. After we backed away from the gate we sat and didn't move for nearly an hour. Nearly an HOUR with minimal communication from the flight crew. Eventually the sun took care of what American Airlines could not and melted the minimal ice. We finally took of a hour late which, in turn, jacked up our connection in Chicago.

For the price of the ticket you get nothing. The plane had 1 bathroom in the back and when the flight attendant did service no one could use it. No announcement just was told to go back to my seat. Ridiculous and rude.

In-flight Wi-Fi didn’t work and the flight was 25 minutes late. The Embraer plane I was on was pretty old and the tray table was broken.

Everything you need to know for your flight from Louisville to South Carolina

Information on your arrival and departure airports