$41 Find Cheap Flights from Louisville to South Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Louisville to South Carolina departing on 6/1. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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KAYAK searches hundreds of travel sites at once for deals on flights to South Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Louisville to South Carolina.
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Louisville to South Carolina.
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Flights Deals

Best South Carolina Flight Deals from Louisville

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours

Charleston
Charlestonnonstop$89
Myrtle Beach
Myrtle Beachnonstop$70
Greenville
Greenville1 stop$271
Columbia
Columbia1 stop$229
Florence
Florence1 stop$835
Charleston
Charlestonnonstop$89
Myrtle Beach
Myrtle Beachnonstop$70
Greenville
Greenville1 stop$271
Columbia
Columbia1 stop$229
Florence
Florence1 stop$835

Cheap Flights from Louisville to South Carolina

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Louisville to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.

Recent round-trip flight deals from Louisville to South Carolina

Recommended round-trip deals departing in the coming months from the most popular airlines that fly from Louisville to South Carolina.
Discover the best prices for you by selecting your travel dates on KAYAK.
 Logo
4:45 pm - 6:23 pmSDF-MYR
1h 38mnonstop
 Logo
2:17 pm - 3:52 pmMYR-SDF
1h 35mnonstop
Sat, May 24 - Sat, May 31
Allegiant Air Logo
8:19 pm - 9:50 pmSDF-SAV
1h 31mnonstop
Allegiant Air Logo
12:02 pm - 1:39 pmSAV-SDF
1h 37mnonstop
$80Allegiant Air
Find Deal
Mon, Jun 9 - Mon, Jun 16
Spirit Airlines Logo
4:45 pm - 6:23 pmSDF-MYR
1h 38mnonstop
Spirit Airlines Logo
4:00 pm - 5:31 pmMYR-SDF
1h 31mnonstop
$81Spirit Airlines
Find Deal
Sat, May 17 - Sun, May 18
Breeze Airways Logo
8:52 pm - 10:28 pmSDF-CHS
1h 36mnonstop
Breeze Airways Logo
7:05 am - 8:58 amCHS-SDF
1h 53mnonstop
$89Breeze Airways
Find Deal
Fri, Sep 5 - Mon, Sep 8
Spirit Airlines Logo
6:26 pm - 7:50 pmSDF-MYR
1h 24mnonstop
Spirit Airlines Logo
4:00 pm - 5:31 pmMYR-SDF
1h 31mnonstop
$92Spirit Airlines
Find Deal
Sun, Jun 1 - Sun, Jun 8
Breeze Airways Logo
8:35 pm - 10:11 pmSDF-CHS
1h 36mnonstop
Breeze Airways Logo
7:05 am - 8:52 amCHS-SDF
1h 47mnonstop
$104Breeze Airways
Find Deal
Fri, Aug 8 - Mon, Aug 11
American Airlines Logo
6:00 am - 11:26 amSDF-HHH
5h 26m1 stop
American Airlines Logo
6:10 pm - 12:30 amHHH-SDF
6h 20m1 stop
$229American Airlines
Find Deal
Sat, Jul 26 - Sat, Aug 2
Delta Logo
6:00 am - 10:18 amSDF-CAE
4h 18m1 stop
Delta Logo
5:40 am - 8:45 amCAE-SDF
3h 05m1 stop
$229Delta
Find Deal
Thu, Jun 12 - Sun, Jun 15
Delta Logo
6:00 am - 11:39 amSDF-MYR
5h 39m1 stop
Delta Logo
12:30 pm - 8:51 pmMYR-SDF
8h 21m1 stop
$229Delta
Find Deal
Wed, Jun 4 - Wed, Jun 11
American Airlines Logo
6:00 am - 12:16 pmSDF-MYR
6h 16m2 stops
American Airlines Logo
4:10 pm - 11:44 pmMYR-SDF
7h 34m2 stops
$239American Airlines
Find Deal
Wed, May 28 - Wed, Jun 4
Useful Info

KAYAK's insights & trends for Louisville to South Carolina flights

Get data-powered insights and trends into flights from Louisville to South Carolina to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest Louisville to South Carolina flight route?

The cheapest price for flight routes found by users searching on KAYAK in the last 2 weeks for round-trip flights from Louisville to South Carolina.

The cheapest ticket to South Carolina from Louisville found in the last 72 hours was to Myrtle Beach, at $60 round-trip. The most popular route is from Louisville (SDF) to Myrtle Beach (MYR), and the cheapest round-trip airline ticket found on this route in the last 72 hours was $60.

What is the cheapest month to fly from Louisville to South Carolina?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Louisville to South Carolina, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Louisville to South Carolina is August, when tickets cost $118 (return) on average. On the other hand, the most expensive months are December and February, when the average cost of round-trip tickets is $378 and $354 respectively.

What’s the cheapest day of the week to fly from Louisville to South Carolina?

The average price of all round-trip flights from Louisville to South Carolina clicked on KAYAK for each day over the last 12 months.

If you are looking for a flight deal from Louisville to South Carolina, look for departures on Fridays and avoid leaving on a Saturday, as it's usually the priciest day. When flying back from South Carolina, Friday is the cheapest day to fly and Sunday is the most expensive.

How far in advance should I book a flight from Louisville to South Carolina?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Louisville to South Carolina, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Louisville to South Carolina, you should book around 2 weeks before departure. For the absolute cheapest price, our data suggests you should book 17 weeks before departure.


Good to know

Low seasonJanuary
High seasonMay
Cheapest flight$41
Best time to beat the crowds but there is an average 7% increase in price.
Most popular time to fly and prices are also 14% lower on average.
Flight from Louisville to Myrtle Beach

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Louisville to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Louisville to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Louisville to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Louisville to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Louisville to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Louisville to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Louisville to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Louisville to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to South Carolina?

    The cheapest time of day to fly to South Carolina is generally at night, when round-trip flights cost $107 on average. Morning departures are around 7% cheaper than evening flights, on average. The most expensive time of day to fly to South Carolina is generally in the evening, which is peak travel time and where the average cost of a ticket is $322.

Top tips for finding cheap flights to South Carolina

  • Looking for a cheap flight? 25% of our users found tickets from Louisville to the following destinations at these prices or less: Charlotte $170 one-way - $321 round-trip

Top 5 airlines serving from Louisville to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Louisville to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Louisville to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.1
Breeze AirwaysOverall score based on 160 reviews
6.6Entertainment
8.8Crew
8.3Boarding
6.7Food
8.2Comfort
Airline reviews

Plane did no snacks and had no wifi or entertainment although the flight was 4 hours long.

8.0 ExcellentAnonymous, Apr 2025PVU - IAD
Read more Breeze Airways reviews

Plane did no snacks and had no wifi or entertainment although the flight was 4 hours long.

My original booking was a nonstop flight. It got changed to a flight with a 6vhour layover that became a 7+ hour lay over. I'll never fly this airline again after this roundtrip is over.

I was surprised at how wonderful it was. The aircraft was clean. The crew was warm and welcoming and as a result the passengers were friendly. One warning the only free thing was water. I kind of liked picking wet hat I was willing to pay for and what I was willing to skip.

The flight wasn’t big on frills, which is fine with me. I flew into Islip MacArthur Airport, which saved me from having to go through LaGuardia to visit friends on Long Island. It was inexpensive and super convenient!

Great experience! This was my first time flying with them and I could not have been happier.

Airplane was newer and very clean, lots of space. Crew was great. There was no food and entertainment but that was expected so not an issue.

I like that the price is right! The airplane is clean and the staff is friendly. We landed safely, so that is always a gold star in my book! Great job!

Purposely delayed the flight by 2 hours and 58 minutes so that they would not have to give me the FAA mandated refund for a delay of 3 hours. Offered flight credit instead. All that is offered on board is water and coffee, everything else costs money. They charge you for carry on and checked bags. Would not fly again.

nice flight. no frills but a 3 hour flight I caught up on my sleep. Stan O

First time flying Breeze, was very impressed. I will use Breeze again.

Delta is my preferred airline. I've traveled with them for years. On time in most cases, good communication, easy to use app. Most planes are pretty nice. I was on a CRJ 700/900 however, which was pretty badly aged inside and needed a refresh. No infotainment, unreliable wifi, best to download before boarding or bring a book. Food choices are really just snacks on this flight, nice variety but about what you'd expect. Great staff and prompt in departure and early arrival too. Overall quite satisfied.

Crew was friendly Love the entertainment in the seat head rest.

Delta flight was on time, seats were comfortable, and crew was nice.

This had nothing to do with Delta… The flights were on time and flawless. The service was excellent. We purchased seats in (aisle/middle) comfort plus since this was a cross country flight. Unfortunately, the woman seated at the window was 300+ pounds and, as might be expected, covered up about a third of the middle seat also. there was absolutely nothing that Delta could have done about that… I just don’t know what the answer should be. If you purchase a seat, you should should be able to use the entire seat and not just the portion that someone else is not sitting/oozing in. Disappointing…there should be something that could be done….I'm just not sure what solution could be.

Delayed take-off. Very small plane so very scary with lots of bumps during the flight. Would never fly Delta on short flights in small 80 seaters plane again! Felt relieved when landed.

The worst part was I was NOT allowed in the lounge even though I was holding a first class ticket and have a premium American Express card. I have flown Business or First Class with many airlines. Delta is the ONLY one who does not extend this courtesy to anyone except people who hold the very expensive American Express card. As a result, I won’t fly Delta if I have any other choice.

A little bumpy ride . No food was being provided due the the turbulence. That was ok it was a short flight to my standards.

Simply outstanding. Their new lounge for Delta One customers is a cut above the rest.

The Dekta Rep that checked us in was great. She's very personable, pleasant, and can tell she enjoys her job.

The plane was old with small storage areas that had problems closing/latching and not enough storage for everyone, and worn, damaged seats. Service was great but feel a little unsafe on such well used planes.

Easiest flights I’ve ever taken. Plane was comfortable without overly crowded seating.

Terrible. Still have not received the refund from them. They sent it to some account that I don't even know. Spoke with costumer service and they are unable to help.

I didn’t like it at all. I miss my second flight because of the delay on Allegiant Air now I m stuck in MCO.

Good, but a bit late on take off after loading. Don't like charging for carry ons!

First time flying with them and will definitely fly again in the future. Crew was so nice and friendly, fought was seamless. They are simple planes, no entertainment, but it’s fine for a short flight or if you have personal devices Rates are competitive, and they did so well with keeping the flight on time after a tropical storm, where other airlines had delays and cancellations.

They boarded passengers that sat in the back of the plane first, making boarding very efficient.

I didn't even take this flight. My plans changed and I couldn't get ahold of customer service and the website kept breaking down during the attempt to change the flight. I wound up taking another airline entirely and eating the cost.

The worst flying experience ever 3 delays. No accommodations. Had to deboard the plane after being delayed.

Posted a 20minute delay but didn’t delay at all. Caused boarding issues and confusion. Also, didn’t release baggage. Took over an hour and 20 minutes to get luggage.

Flight was good, boarding was a breeze, flight attendants were friendly and professional. There was a medical issue with another passenger and the crew handled it in a calm and professional way.

Several delays. Next flight was worse. Did not arrive home until 2am PT

Very helpful ground crew after an earlier flight delay and being rebooked on a different flight.

Everything about the flight was lovely…We left early, arrived early, cabin crew were efficient and helpful. Flight was easy and most pleasant.

First world problems, but still… We were seated in first class and asked for a cocktail on a very short, 50 minute flight. After our drink order was taken, a half hour went by, and we noticed that every other person in the small plane had been served except for us. We got up to ask about it, the drinks finally came, then were taken away three minutes later since the flight was so short. Really strange situation, on the other hand, we were in Utah.

We missed our flight. The boarding pass had the wrong gate and by the time we received the text from Kayak, our flight was already gone. I’ll never use Kayak again and will go direct to the airlines in the future.

Boarding took forever, the plane was cramped and cold, and the seatbelt song came on constantly throughout the red eye flight with a loud pre-recorded message playing each time

Cabin felt crammed Snacks are lame But crew was super efficient getting us out on time despite delay

Took off on time and successfully avoided weather that looked to be a problem along the way

There were five broken seats on the plane. The crew was very rude in telling people they had to get off the plane and get a flight the next day. No call for volunteers, but telling people they had to get off. One woman was flying with her elderly mother and daughter and was told she had to leave or all three had to leave. Fortunately, a volunteer offered to stay. The situation was handled poorly.

The flight to Tokyo AA61 took off about two hours late, but then had to turn back. By that time the crew had to be replaced. Then they kept promising to take off in an hour, then in 3, then switch to the next day.

I mean, it’s Spirit. But it was frustrating to have our flight canceled, get bumped to a later flight, and then Spirit was unwilling to check our bag until 4 hours before our flight… tell us we could not sit in the waiting area’s chairs… and really negative experience getting checked in and dropping the bag.

Not having it be changed after we bought the flight tickets from a direct flight getting in at a reasonable time to a connecting flight red eye of 9 hours, so that we would lose our 35 dollars in nonrefundable insurance would've been great! Our country really does need low-cost carrier options, but this type of "service" ain't it. Fortunately, had a little better success with them flying to and from San Juan PR last month at least.

All was good expecting the seats need a bit of cushion. Besides that I can’t complain.

You get what you pay for, and the flights went smoothly. There’s no reclining chairs, no screens, And there isn’t always wifi, but the plane was clean and staff was friendly and the takeoff/landing were smooth.

The only positive is that the flight made it both ways. Getting charged for every little thing after the cost of the ticket itself is comical, considering how the plane and services are as bottom-tier as possible. The self check-in kiosks are useless. It’s nice to think that you can print your boarding pass, tag your checked bag, and then just drop it off. But no, they still make you go through the line once you finish- what’s the point of the self check-in then? Any questions for the staff seem like the biggest inconvenience and were met with condescending responses. This was my first and now last time ever flying with Spirit. After all the extra costs, subpar plane and staff, I see no value. I’d rather drive the 13 hours than give Spirit another dime.

The flight was fine however what started as a reasonable priced ticket could have become an overpriced ticket with additional charge for carry on as well as checked bag $79 per bag per person each way. Additional charge for choosing one’s seat, additional charge for beverage and snack, we were on what was described as a new plane yet there were no audio/visual on the jet. A bare bones service but not at a bare bones price. Will think twice before flying Spirit again. 😕

Flight was delayed a bit, but that was expected (and updated), so really not bad at all for the price. Could’ve used one less email asking me to upgrade my seat; otherwise no significant complaints

I love Spirit. New aircraft, great cabin service, the airfares are low cost which helps me visit my hospitalized daughter anytime I can without paying a fortune.

Flight was 2hours late they had no crew or the pilot.

I paid for streaming wifi and the connection was poor.

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