$120 Find Cheap Flights from Mexico to Panama

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1 adult, Economy, 0 bags

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Booking Insights

KAYAK's insights & trends for flights to Panama

Get data-powered insights and trends for flights to Panama to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest flight to Panama?

These are the best round-trip prices found by users searching on KAYAK in the last 72 hours.

The cheapest ticket to Panama from Mexico found in the last 72 hours was to Panama City, at $164 round-trip. The most popular route is Cancún (CUN) to Panama City (PTY) and the cheapest round-trip airline ticket found on this route in the last 72 hours was $164.

How much is a flight to Panama?

The average and cheapest price for all round-trip flights to Panama from each origin found by users searching on KAYAK in the last month.

A flight to Panama costs $387 on average. The cheapest price found on KAYAK in the last 2 weeks was $164 for the route Mexico City (MEX) to Panama City (PTY). The most popular routes on KAYAK are Mexico City to Panama City which costs $472 on average, and Cancún to Panama City, which costs $348 on average.

See prices from:

What is the cheapest month to fly from Mexico to Panama?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for flights from Mexico to Panama, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Mexico to Panama is July, when tickets cost $307 (return) on average. On the other hand, the most expensive months are February and January, when the average cost of round-trip tickets is $376 and $351 respectively.

How far in advance should I book a flight from Mexico to Panama?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights to Panama, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Mexico to Panama, you should book around 4 weeks before departure, which saves you about 20% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 14 weeks before departure.

Which is the cheapest airport to fly into in Panama?

Prices will differ depending on the departure airport, but generally, the cheapest airport to fly to in Panama is Panama City Tocumen Intl Airport (PTY), with an average flight price of $324.

Good to know

Low seasonJune
Cheapest flight$120
Best time to beat the crowds with an average 5% drop in price.
Most popular time to fly and prices are also 3% lower on average.
Flight from Cancun to Panama City

FAQs for booking flights from Mexico to Panama

  • How does KAYAK find such low prices on flights from Mexico to Panama?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Mexico to Panama.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Mexico to Panama?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Mexico to Panama is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Mexico to Panama?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Mexico to Panama with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Mexico to Panama?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Mexico to Panama up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest day to fly to Panama?

    Based on KAYAK data, the cheapest day to fly to Panama is Wednesday where round-trip tickets can be as cheap as $436. On the other hand, the most expensive day to fly is Thursday, where round-trip prices are $503 on average.

  • What is the cheapest time of day to fly to Panama?

    The cheapest time of day to fly to Panama is generally at night, when round-trip flights cost $434 on average. Morning departures are around 2% more expensive than evening flights, on average. The most expensive time of day to fly to Panama is generally in the afternoon, which is peak travel time and where the average cost of a ticket is $571.

Reviews of the top 3 airlines serving from Mexico to Panama

 
Need help choosing which airline to fly with from Mexico to Panama? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.6
Copa AirlinesOverall score based on 1558 reviews
6.8Food
7.4Comfort
8.1Crew
6.8Entertainment
7.8Boarding
Airline reviews

Seats were awful. Media should have been included for such a long flight.

4.0 OkayPaul, Jan 2026
LIM - PTY
Read more Copa Airlines reviews

Seats were awful. Media should have been included for such a long flight.

There should be a warning regarding the quality of the aircraft on the website as we reserve the tickets. There was no TV or any type of screen onboard. The wifi they offer is good for nothing. Traveling 9 hours straight with kids and no type of entetainment was horrible. I wish I had been informed prior so I could buy a ticket with another airline. The food was a joke too. A very tiny portion per passenger. They also charged $100 per checked bag. With United I used to pay $60. So, fair to say that I wont be flying Copa anymore. Their aircraft was super old, outdated, no entertainment, with nearly no onboard food.

I always enjoy flying Copa. There are very few airlines where I can enjoy a comfortable sleep in-flight. The snacks weren't the best, but they sufficed. The in-flight entertainment was fantastic, and I crossed another movie off my watch list.

Very strict carry on rules meant most of the plane had to gate check their luggage. As is often the case had things that were broken because of this, but I appreciated not being charged to gate check. Otherwise good flight and great crew once on the plane

Simply as follows:- First, there was no vegetarian option for the meal Second, only 2 washrooms for the entire economy class.

I liked the meatloaf the chicken was awful but the plane was on time and got there and the staff was nice.

They were super friendly bumped me up to exit row free of charge, All flight legs were on time

Boarding was quick & efficient; they gave boarding groups due priority; staff & air crew were very cordial and helpful, pleasant flight.

Cops Airlines is fantastic! The level of care and professionalism provided by the entire crew was top rate.

the food served was an embarrassment. No connection for charging the cellphone... What a crappy airline.

It was OK. The flight is pretty long for the airlines to only offer a simple sandwich on business class. The entertainment is similar to that on other Skyteam members. Ultimately the airline lost my bag and didn’t deliver it to me until the next day after a lengthy lost baggage report.

Good, the flight from Miami to Mexico City was better than Mexico City to Miami

Aeroméxico cancelled my ticket without advice AND It make a last minute mess in my intinerary, no solving my situation, bad advice and bad customer service

Flight was on time, good service, but there was no free WiFi, even for first class passengers

It was good in general. The Crew during the flight were very nice at all times.

The ground staff were not as friendly and nice to the passengers as the air crew. Flight attendants, cockpit crew were great and very nice to everyone on board.

My flight was delayed, then I got transferred to a new flight that was also delayed- which wasn’t Aeromexico’s fault, it was because of weather conditions. Most of the crew was very nice and patient, except for one or two flight attendants who were rude. The entertainment wasn’t on, so all the screens were off.

My wife's entertainment system did not work. Payed for flight upgrade but did not receive advertised "free WiFi".

Annoying that we had to go to departures and get boarding passes. Should allow us to be booked all the way through, this is the only airline i have this problem with in MEX. Late boarding and take off

the guy in front of me put his seat back immediately...and then left it back including thru landing and taxiing to the runway. attendants did not check/ask him to put it up for landing.

It was delayed and I lost my connection flight to Cali and I missed my Mom's funeral and avianca lost my check in luggage

I upgraded to businesses class. Because of that the flight was comfortable.

I actually upgraded to the medium level of seats from basic and even doing that it may have been physically the most uncomfortable flight I have ever had. They packed everyone like is a train to death camp. It was a red eye so I hoped to get some sleep but it was physically impossible to find a comfortable way to rest. I met other folks on the same flight and they said the same thing. It was an utterly miserable flight and if I have any other options I will never fly with them again

Avianca has transitioned from full service legacy airline to "low cost" but has now became a strange hybrid (minimum leg space, started offering business class in domestic flights again, charges passenger for printing boarding pass, etc.). National and international coverage and destinations are really wide but service is not at its best

Provide free food and drinks on an international flight. Add updated head rests

The flight attendant smashed her beverage cart into my knee, causing significant amount of pain. The seats were extremely uncomfortable. No food or drink is offered unless you want to pay the ridiculous prices for it. The schedule of flying in the overnight hours is also very uncomfortable.

Here we have another airline flying to Guatemala but doesn't have a plus or a less, just in the middle. Why? Well, first we don't have even free water Movie selection is poor Seats don't recline in some places Food selection is carb based Forgot to mention, customer service on the web is the worst. Good things; Very reliable on schedule Kind crew

Last seat of Bussines Class it does recline but passenger seating behind kept pushing since they did not have space once my seat was reclined

I like the crew members they're very friendly. Clean plane. The flight was on time. I dont like the comfort my car seat its better that the plane seats. They charge for everything. This airline was very good. Now it's a low cost airline

6 hour flight and have to pay for everything 100 dollars to add a carry-on bag is insane

Everything you need to know for your flight to Panama

Cabin class types available on flights to Panama

Cabin classes available on flights to Panama. Prices are the lowest found on KAYAK over the last 7 days. Price and availability is not guaranteed.