$309 Find Cheap Flights from Myrtle Beach to Italy - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to Italy departing on 10/15. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Myrtle Beach to Italy

Cheapest round-trip prices found by our users on KAYAK in the last 5 days
Florence
Florence2 stops$781
Naples
Naples2 stops$925
Palermo
Palermo1 stop$980
Catania
Catania2 stops$1,273
Florence
Florence2 stops$781
Naples
Naples2 stops$925
Palermo
Palermo1 stop$980
Catania
Catania2 stops$1,273
Booking Insights

KAYAK's insights & trends for Myrtle Beach to Italy flights

Get data-powered insights and trends into flights from Myrtle Beach to Italy to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Myrtle Beach to Italy?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Myrtle Beach to Italy, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Myrtle Beach to Italy is February, when tickets cost $507 (return) on average. On the other hand, the most expensive months are June and May, when the average cost of round-trip tickets is $1,775 and $1,519 respectively.

Good to know

Cheapest flight

$309
Most popular time to fly with an average 31% increase in price.
Flight from Myrtle Beach to Rome

FAQs - booking Italy flights

  • How does KAYAK find such low prices on flights from Myrtle Beach to Italy?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to Italy.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to Italy?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Myrtle Beach to Italy is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to Italy?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Myrtle Beach to Italy with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to Italy?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Myrtle Beach to Italy up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Myrtle Beach to Italy

 
Need help choosing which airline to fly with from Myrtle Beach to Italy? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
DeltaOverall score based on 8504 reviews
7.8Comfort
7.2Food
8.1Boarding
7.8Entertainment
8.5Crew
Airline reviews

Delta staff was exceptionally helpful and considerate. However, the first two of three flight legs were delayed making connections tentative and stressful.

6.0 GoodAnonymous, Jul 2026
Read more Delta reviews

Delta staff was exceptionally helpful and considerate. However, the first two of three flight legs were delayed making connections tentative and stressful.

This wasn't my experience with Delta. It was just the Pegasus flight. Seats were very hard. Staff was kinda rough. Not very nice. Charged me for snacks. For a 4 hour flight I would've expected more.

Excellent service, I love the soft blush pink mood lighting on the 767-400ER during meal service. The overhead gasper vents on the 767-400ER were also very strong with a lot of airflow to keep me comfortable on my flight.

I had a flight cancel and had it rerouted. When the rerouted they put me at a window seat instead of an isle. It was hard sitting by the window because the couple with masks on were making out. I get motion sickness which is why I need to have the isle seat.

They ended up paying for the bag twice, but the counter wouldn't take my baggage receipt. Left it to me to resolve. Not sure how to resolve the issue.

Our bag was lost so that made unnecessary chaos On our trip

The plane was old with small storage areas that had problems closing/latching and not enough storage for everyone, and worn, damaged seats. Service was great but feel a little unsafe on such well used planes.

I just can’t understand why are you sell to many tickets ???? We had to wait 2 hours before 13 people from our flight take money and go to next day flight!

The only real hiccups in the flight were things beyond Delta’s control - turbulence which delayed food service and a departure delay caused by some VIP plane which stopped all departures and landings for 30 minutes - and was never explained to us by the crew. Otherwise good flight. I would fly Delta again.

The plane was frigid, and leaked water from the ceiling all over me and my seat.

The first flight was delayed by an hour and a half, so we missed the second flight. They rebooked us on the later flight and I have to sit in the middle for more than 5 hours. Terrible experience. No more American Airlines.

Very good I can’t complain one bit. Thank you American Airlines for making my flight enjoyable and safe!

Flight was fine, but not having WiFi was a major negative

Everything was excellent and I enjoyed myself. Thank for everything

One of our group members was struggling to walk. In Charlotte we asked for a wheelchair and she was accompanied by Desmond. I was impressed by his patience and attention. In Boston she received the same service. I didn’t get the name of the helper but she went above and beyond in assisting us. A great AA service

I was trying to take 2 one and a half hour one way trips and I experienced almost 20 delays over the course of those two trips. Only a few of them were due to weather the rest was disorganization

Would have thought that they would gas up plane before everyone got on board

The flights were terribly delayed and then cancelled which forced us booking another night at the hotel. Very poor management from American Airlines

When my flight was delayed due to weather, I was rebooked to another flight since it showed that I would miss my connection. It was a lot of work to get back onto my originally connecting flight which was also delayed. That part caused a lot of stress and frustration. The ticketing agent at the desk was not very helpful.

Flight was delayed 5 hours causing me to miss my connecting flights

Good flight, no turbulence. I felt safe and comfortable which is really important when I am just a passenger.

Someone switched seats in business class so they could sit together and we were left apart (3). Very disappointing. Staff did nothing

Worst airline in the world. They downgraded me from business class to economy with no compensation.

I paid for a very expensive Business Class seat to and from Cairo Egypt from Charleston SC. There was partnership from states to London using American Airlines. That leg was amazing. The British Airlines leg was a joke. They used the standard no leg room 3 by 3 seats. A tray was put on the middle seat. The trip was 5 hours, from London to Cairo, thus my BC purchase. There was no screen proving tv/movie options, only a small device plug. The fold down tray and the bag of peanuts were typical of normal short run flying. The one toilet was located in the galley. We all got to know each other well. This was my first and last trip with British Airlines. I now understand why they would NEVER give me a seat chart so that I could make a selection.prior to departure. It honestly would not have made a difference, there were less than 50% of occupied seats. Apparently everyone got the memo but me. I have never felt so cheated as with that trip, got to so another going back to London, yeah. I will be sending a letter to customer service and asking for a refund. I will be photos comparing the two BC legs. OH, one more thing. The FC ticket holders got bulkhead and exit row seats. I know they had to be thrilled

The airline was efficient and accommodating to work with though there was a delay. Appreciate the service and smooth experience!

Flight attendant kept banging her cart into my aisle seat. Hard. Couldn’t lean seat back. Should be warned of limitations when booking seat

Flight delay of 4 1/2 hours with no reason for over 3 hours. Missed our connection in Rome & had to pay for an additional flight.

Flight was delayed hours which caused us to miss our connection and lose a day of vacation. CHS staff was great.

I mentioned in advance that I am gluten free, however, they did not have any options on the plane for me. That was disappointing. Otherwise, the flight was totally fine.

The flight was delayed for several hours. After many hours of waiting, they said it was delayed until the next day. This is completely understandable, as the staff had to wait on Boeing to approve the plane. However, the staff said hotel and meal vouchers would be issued via email (they never were). An hour after leaving the airport, our flight was cancelled.

Everything you need to know for your flight from Myrtle Beach to Italy

Information on your arrival and departure airports