$405 Find Cheap Flights from Panama City to Italy

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to Italy departing on 8/29. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Flight Deals

Book Cheap Panama City to Italy Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama City to Italy that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to Italy

Mon, Apr 13 - Mon, Apr 20
United Airlines Logo
4:57 pm - 10:20 am
ECP
-
FCO
58h 23m
2 stops
United Airlines Logo
12:25 pm - 9:59 pm
FCO
-
ECP
40h 34m
2 stops
$776United Airlines
Mon, May 11 - Thu, May 21
American Airlines Logo
1:34 pm - 10:20 am
ECP
-
FCO
13h 46m
2 stops
American Airlines Logo
11:05 am - 11:40 pm
FCO
-
ECP
19h 35m
2 stops
$892American Airlines
Mon, Apr 13 - Mon, Apr 20
KLM Logo
11:01 am - 10:50 am
ECP
-
FCO
16h 49m
1 stop
KLM Logo
9:45 am - 7:36 pm
FCO
-
ECP
16h 51m
1 stop
$907KLM
Mon, Apr 13 - Mon, Apr 20
Delta Logo
11:01 am - 10:50 am
ECP
-
FCO
16h 49m
1 stop
Delta Logo
12:45 pm - 11:12 pm
FCO
-
ECP
17h 27m
2 stops
$908Delta
Fri, Apr 17 - Fri, Apr 24
United Airlines Logo
2:19 pm - 10:00 pm
ECP
-
FCO
24h 41m
2 stops
United Airlines Logo
12:25 pm - 9:59 pm
FCO
-
ECP
40h 34m
2 stops
$915United Airlines
Tue, Jun 9 - Wed, Jun 24
Delta Logo
1:30 pm - 8:15 pm
ECP
-
VCE
23h 45m
2 stops
Delta Logo
3:25 pm - 10:46 pm
VCE
-
ECP
14h 21m
1 stop
$925Delta
Tue, Jun 9 - Thu, Jun 25
Delta Logo
1:30 pm - 8:15 pm
ECP
-
VCE
23h 45m
2 stops
Delta Logo
1:20 pm - 8:17 am
VCE
-
ECP
25h 57m
2 stops
$929Delta
Fri, Apr 17 - Fri, Apr 24
United Airlines Logo
2:19 pm - 3:05 pm
ECP
-
FCO
17h 46m
2 stops
United Airlines Logo
9:45 am - 1:23 pm
FCO
-
ECP
34h 38m
1 stop
$938United Airlines
Fri, May 8 - Fri, May 15
United Airlines Logo
10:30 am - 10:00 pm
ECP
-
FCO
28h 30m
2 stops
United Airlines Logo
12:25 pm - 1:18 pm
FCO
-
ECP
31h 53m
2 stops
$940United Airlines
Fri, Jul 17 - Sat, Aug 1
Air Europa Logo
7:05 pm - 8:55 am
ECP
-
VCE
30h 50m
1 stop
Air Europa Logo
9:25 am - 10:46 pm
VCE
-
ECP
44h 21m
2 stops
$1,072Air Europa
Booking Insights

KAYAK's insights & trends for Panama City to Italy flights

Get data-powered insights and trends into flights from Panama City to Italy to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Panama City to Italy?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Panama City to Italy were found on Delta ($908) and United Airlines ($938).

Good to know

Cheapest flight$405
Most popular time to fly and prices are also 17% lower on average.
Flight from Panama City to Venice

FAQs - booking Italy flights

  • How does KAYAK find such low prices on flights from Panama City to Italy?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to Italy.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to Italy?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Panama City to Italy is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to Italy?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Panama City to Italy with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to Italy?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Panama City to Italy up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Panama City to Italy

 
Need help choosing which airline to fly with from Panama City to Italy? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8242 reviews
7.9Comfort
8.5Crew
7.2Food
8.1Boarding
7.8Entertainment
Airline reviews

An awesome flight crew. FC seat cushion just doesn’t cut it for a 3+ hour flight.

10.0 ExcellentBob, Feb 2026
FLL - MSP
Read more Delta reviews

An awesome flight crew. FC seat cushion just doesn’t cut it for a 3+ hour flight.

Delta continues to set the benchmark for traveler-friendly service with minimal disruption and clear communication within the mainland US (coast to coast). I am consistently pleased to be a Delta customer, and this experience once again met my expectations. There was a brief delay departing from MIA due to a technical issue that required the aircraft to return to the gate. However, the situation was handled professionally and transparently. Fortunately, my planned layover allowed ample buffer time, so the adjustment caused no stress. Overall, another smooth and reassuring experience.

Totally worth the miles to upgrade to Delta Comfort. Plenty of legroom.

This was my first time flying Delta ever and I had a great experience!

The flight was great as well as the airline staff

Comfort seating was on the tight side. Maybe it was a smaller plane(?)

Excellent flight and got us around tough weather. Only issue was seat TV did not work and crew tried to reboot.

Connection through Atlanta was difficult. Mechanical issue on plane caused a two hour delay. New gate was a mile away.

No WiFi. Comfort plus should have alcohol provided, crew only offered water or tea. Who the heck wants tea?

I have diamond medallion status and usually we are in comfort plus . We were in main this time ( which was fine ) and my husband wanted wine . I have at least 10 vouchers for drinks that are good for this year and next! The attendant would not take the picture of the voucher as proof and never came back to check as She asked me to pull it up on delta Wi-Fi. Instead my husband just used his Amex to buy the wine . Disappointing!!!

Crew is not the cheerful type. very slow meal service (this is their style as have flown this many times)

I’m grateful for the KLM Air France shuttle bus service to Ottawa. However due to construction and other issues related to the chaotic Uber pickup system at YUL, it’s a challenge to find the Kelios bus service to Ottawa. The signs are not clear or even available. No staff to guide passengers. It’s a stressful experience.

At the airport, terrible, I do not want to even remember it. It was too humiliating for a business class passenger.

Flight was ok but lack of communication cost me to literally beg to be put on another flight as connecting flight had departed

They forgot to serve food and the crew was very unfriendly. Never experienced such a bad KLM flight. Usually fly from Toronto. New York was different.

Couldn’t get boarding pass in SLC even with help from a redcoat, so had to find a desk in AMS to get boarding pass. Technical problems so not sure why. Very inconvenient. The KLM app is not as user friendly as most apps. Also had to wait almost an hour on the tarmac for a fuel truck, which caused us to miss a connecting bus in LUX.

The immigration hall in Amsterdam was understaffed, so passport checking was slower than it should be for a major airport. They need to get the automatic readers up and running for non EU passport holders. Waiting in line after a long flight feels a bit abusive.

Over 1 Hr delay. No APU so no AC on ground. Plane was hot during boarding and then they closed the doors over 20 minutes before engine start so interior of plane was steamy hot and stuffy. Could have been helped by opening doors until ready to depart.

First of all we couldn’t check in online, then we learn at the airport we were on stand by for KLM’s mistake of overbooking. The seats were not comfy at all. Our luggage got lost.

KLM remains a quality flag carrier airline which maintains its standards whilst all their competitors are lowering theirs.

Overall good. The pilots and flight attendants are excellent! The equipment was the issue on my First flight as they had to wait for a part to be installed. So the take off was at least 30 minutes later.

For my arriving destination, we were delayed multiple times to the point that we arrived 6 hours after we were originally scheduled. On my flight home, they overbooked and involuntarily removed passengers (including me) from the plane. It was not a good experience.

Boarding is always an ordeal. Less dogs on flights. I am highly allergic to dogs and cats. Why are there so many animals these days?

Horrible. Got delayed many hours because their pilot wasn't trained for night landing at the airport and a rain delay made it a night landing. We have to wait hours for a qualified crew. They give us 12 dollar meal vouchers but most everything in the airport was closed and definitely more expensive than the vouchers.

I am an AA flyer for a very long time... AA has yet to disappoint.

Everything was good. Flight was very full so crew was busy. After we boarded and plane pulled away from the gate, we were delayed about 40 minutes- sitting on the runway - due to weather en route or at the destination. While weather is not the fault of the airline- it’s terrible to sit on a plane and not moving.

The smell from the bathroom kept wafting through the cabin. It made people sick.

Waited for oxygen tanks for 30 minutes after boarding was complete.

Awful. Original flight was delayed 5 hours. Had to to take a connecting flight instead of direct. Had a 4 hour layover. I missed all of my morning meetings getting in 5 hours later than I was supposed to and had to change to take a later flight the next day to get them back in which cia time another $150.

On time on a day with lots of weather cancellations on other flights. Thank you for getting me home during a winter storm!

Everything you need to know for your flight from Panama City to Italy

Information on your arrival and departure airports