PTY - CUZ

$343 Find Cheap Flights from Panama City to Cusco - Compare and Save

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1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$465
Typical prices: $401-$593
Avianca
Sun 2/4Fri 2/9
PTY - CUZ • 1 stop
Cheapest one-way
$343
Typical prices: $226-$339
Multiple Airlines
Thu 11/8
PTY - CUZ • 1 stop
Nonstop flights
Not available
There are currently no direct flights between Panama City and Cusco. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to book
22 weeks
in advance
Our data shows that travelers who book at least 22 weeks in advance save around 38% compared to booking last minute.
Insights
Insights
When to travel
February
Cheapest • 15% price drop
October
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Bogotá El Dorado (BOG)
Cheapest • Avg $480 (round-trip)
Lima J Chavez Intl (LIM)
Shortest trip • 7h 35m (one-way)
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Insights
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We hope you love your trip to Cusco!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Panama City to Cusco (PTY-CUZ)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to Cusco

Fri, Feb 5 - Tue, Feb 9
Avianca Logo
6:10 pm - 11:25 amPTY  Panama City Tocumen Intl-CUZ Cusco Velazco Astete
17h 15m1 stop Bogotá El Dorado
Avianca Logo
5:10 pm - 9:10 amCUZ  Cusco Velazco Astete-PTY Panama City Tocumen Intl
16h 00m1 stop Bogotá El Dorado
$465Avianca
Thu, Feb 4 - Tue, Feb 9
Avianca Logo
2:30 am - 11:25 amPTY  Panama City Tocumen Intl-CUZ Cusco Velazco Astete
8h 55m1 stop Bogotá El Dorado
Avianca Logo
5:10 pm - 9:10 amCUZ  Cusco Velazco Astete-PTY Panama City Tocumen Intl
16h 00m1 stop Bogotá El Dorado
$465Avianca
Thu, Feb 11 - Wed, Feb 17
Avianca Logo
2:30 am - 11:25 amPTY  Panama City Tocumen Intl-CUZ Cusco Velazco Astete
8h 55m1 stop Bogotá El Dorado
Avianca Logo
5:10 pm - 9:10 amCUZ  Cusco Velazco Astete-PTY Panama City Tocumen Intl
16h 00m1 stop Bogotá El Dorado
$465Avianca
Fri, Feb 5 - Wed, Feb 10
Avianca Logo
2:30 am - 11:25 amPTY  Panama City Tocumen Intl-CUZ Cusco Velazco Astete
8h 55m1 stop Bogotá El Dorado
Avianca Logo
5:10 pm - 1:20 amCUZ  Cusco Velazco Astete-PTY Panama City Tocumen Intl
8h 10m1 stop Bogotá El Dorado
$465Avianca
Sat, Oct 31 - Wed, Nov 4
Avianca Logo
2:30 am - 11:25 amPTY  Panama City Tocumen Intl-CUZ Cusco Velazco Astete
8h 55m1 stop Bogotá El Dorado
Avianca Logo
5:10 pm - 1:20 amCUZ  Cusco Velazco Astete-PTY Panama City Tocumen Intl
8h 10m1 stop Bogotá El Dorado
$559Avianca
Sat, Oct 31 - Wed, Nov 4
Avianca Logo
2:30 am - 11:25 amPTY  Panama City Tocumen Intl-CUZ Cusco Velazco Astete
8h 55m1 stop Bogotá El Dorado
Avianca Logo
5:10 pm - 1:20 amCUZ  Cusco Velazco Astete-PTY Panama City Tocumen Intl
8h 10m1 stop Bogotá El Dorado
$641Avianca
Fri, Feb 5 - Tue, Feb 9
Multiple Airlines Logo
8:43 am - 4:05 pmPTY  Panama City Tocumen Intl-CUZ Cusco Velazco Astete
7h 22m1 stop Lima J Chavez Intl
Multiple Airlines Logo
3:35 pm - 5:26 amCUZ  Cusco Velazco Astete-PTY Panama City Tocumen Intl
13h 51m2 stops Lima J Chavez Intl Chiclayo Cornel Ruiz
$742Multiple Airlines
Fri, Feb 5 - Tue, Feb 9
Multiple Airlines Logo
7:34 pm - 6:35 amPTY  Panama City Tocumen Intl-CUZ Cusco Velazco Astete
11h 01m1 stop Lima J Chavez Intl
Multiple Airlines Logo
4:25 pm - 5:26 amCUZ  Cusco Velazco Astete-PTY Panama City Tocumen Intl
13h 01m2 stops Lima J Chavez Intl Chiclayo Cornel Ruiz
$765Multiple Airlines
Sat, Feb 6 - Wed, Feb 10
Multiple Airlines Logo
1:21 pm - 6:35 amPTY  Panama City Tocumen Intl-CUZ Cusco Velazco Astete
17h 14m2 stops Medellín Jose Maria Cordova Intl Lima J Chavez Intl
Multiple Airlines Logo
5:10 pm - 1:20 amCUZ  Cusco Velazco Astete-PTY Panama City Tocumen Intl
8h 10m1 stop Bogotá El Dorado
$808Multiple Airlines
Thu, Oct 8 - Sun, Oct 11
Multiple Airlines Logo
9:45 pm - 6:15 amPTY  Panama City Tocumen Intl-CUZ Cusco Velazco Astete
8h 30m1 stop Lima J Chavez Intl
Multiple Airlines Logo
6:55 am - 2:45 pmCUZ  Cusco Velazco Astete-PTY Panama City Tocumen Intl
7h 50m1 stop Lima J Chavez Intl
$920Multiple Airlines
Booking Insights

Price, demand and travel trends for Panama City to Cusco flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from Panama City to Cusco?

Round-trip flights from Panama City to Cusco typically range from $401 to $593. The lowest price found in the past 5 days was $465, on Avianca.

What's the cheapest day of the week to fly from Panama City to Cusco?

Based on deals KAYAK users found in the last 12 months, Tuesday is the cheapest day of the week to fly from Panama City to Cusco. It’s 15% cheaper than the average day, while Friday is the most expensive, with prices 24% higher.

What’s the cheapest month to fly from Panama City to Cusco?

•February is the cheapest month to fly from Panama City to Cusco at $401 round-trip.
•August ($648) and July ($586) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 61% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

When are flights from Panama City to Cusco the cheapest?

Flights from Panama City to Cusco are cheapest 22 weeks before departure. Booking in this window typically costs about 38% less than the average last-minute fare (within 2 weeks of the flight), based on KAYAK data.

Find deals

Key details for Panama City to Cusco flights

Low season

January

Cheapest flight

$343
Beat the crowds with an average 16% drop in travelers.
The most popular month to fly with an average 56% increase in travelers.
One-way flight from Panama City to Cusco

When to book flights from Panama City to Cusco

Are your dates flexible? Find out the best times to travel from Panama City to Cusco based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Panama City to Cusco flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from Panama City to Cusco?

    Only Economy Class is available on flights from Panama City to Cusco.

  • How long is a flight from Panama City to Cusco?

    A nonstop flight from Panama City to Cusco takes 00m, covering 1,642 miles.

  • Do I need a passport to fly from Panama City to Cusco?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • How much should I expect to pay for a Panama City to Cusco flight?

    Round-trip flights from Panama City to Cusco range from $401 to $593, with an average of $471 over the past 12 months. Anything below $401 counts as a good deal.

  • How expensive are last-minute Panama City to Cusco flights?

    Last-minute fares on this route (booked within two weeks of departure) run 38% above the $471 route average. Book 22 weeks before departure for the lowest fares.

  • Have flight prices from Panama City to Cusco changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $465 to $1,892. That means the highest observed fare was about 4x higher than the lowest one.

  • How are flight prices from Panama City to Cusco looking right now?

    One-way fares from Panama City to Cusco are currently higher than usual. Average one-way flight prices are about $374, which is 39% above the typical average for this route.

  • What car rental options are available at Cusco Velazco Astete Airport (CUZ)?

    Cusco Velazco Astete Airport (CUZ) hosts 5 major car rental companies, with daily rates starting from around $3 for economy cars. Top options include:

    • Sixt
    • Hertz
    • Thrifty
    • Europcar
    • Dollar

  • Which airports can I use when flying from Panama City to Cusco?

    Flights from Panama City to Cusco usually depart from Panama City Tocumen Intl (PTY) and arrive at Cusco Velazco Astete (CUZ).

  • Which airports do connecting flights from Panama City to Cusco pass through?

    Connecting flights from Panama City to Cusco most commonly pass through:

    • Bogotá El Dorado (BOG) - 85% of one-stop connections
    • Lima J Chavez Intl (LIM) - 15% of one-stop connections

  • Can I save money by using flexible dates for flights from Panama City to Cusco?

    Yes. Flexible dates can save you up to 32% on flights from Panama City to Cusco. Tuesday is the cheapest departure day at $401 round-trip on average, while Friday is the most expensive at $586, a difference of $185.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • How much time can I save by choosing a different layover airport from Panama City to Cusco?

    Flying via Lima J Chavez Intl (LIM) gives the shortest average 1-stop total travel time at 7h 35m, compared with 8h 59m via Bogotá El Dorado (BOG).

  • What popular places can I visit in Cusco?

    Some of the most popular sights in Cusco are Plaza de Armas, UNSAAC-Yale International Center for the Study of Machu Picchu and Inca Culture and Cusco San Pedro Market. These are among the most viewed places in Cusco on KAYAK.

Your guide to booking Panama City to Cusco flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Tuesday departure and avoid flying on Friday. On this route, Tuesday flights average $401, about $185 less than Friday fares (32% savings) based on the last 12 months.
  • For the best chance at a low fare, aim to book around 22 weeks before you fly. On this route, that window historically saves about 38% versus last-minute pricing (KAYAK booking data, last 12 months).
  • If you can choose when to travel, plan your Panama City to Cusco trip for February. Fares historically average $401 round-trip in that month - typically $247 less than the most expensive month, which is August (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Cusco Velazco Astete Airport.

    • Polo Corporativo San Sebastian
    • Ureta Hotel
    • San Francisco Cusco Hotel

More options for your flight from Panama City to Cusco

Complete your trip to Cusco with a hotel stay or car rental

Car rentals in Cusco
Hotels in Cusco
Vacations in Cusco