$436 Find Deals on Flights from Santa Cruz de la Sierra - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santa Cruz de la Sierra to Worldwide departing on 8/21. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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Find Cheap Flights from Santa Cruz de la Sierra

Where can I fly from Santa Cruz de la Sierra?Prices from VVI, departing Sat 8/1 and returning Sat 8/8

Book Cheap International Flights from Santa Cruz de la Sierra

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santa Cruz de la Sierra that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip international flight deals from Santa Cruz de la Sierra to anywhere

Fri, Oct 9 - Thu, Oct 15
Multiple Airlines Logo
5:25 am - 5:40 pm
VVI
-
CUN
13h 15m
1 stop
Multiple Airlines Logo
6:20 pm - 2:30 am
CUN
-
VVI
31h 10m
1 stop
$723Multiple Airlines
Mon, Sep 14 - Tue, Sep 22
Avianca Logo
3:35 am - 11:35 am
VVI
-
CUN
9h 00m
1 stop
Avianca Logo
4:50 pm - 2:30 am
CUN
-
VVI
8h 40m
1 stop
$724Avianca
Sat, Aug 1 - Thu, Aug 6
Copa Airlines Logo
11:47 am - 9:58 pm
VVI
-
CUN
11h 11m
1 stop
Copa Airlines Logo
7:01 am - 10:40 pm
CUN
-
VVI
14h 39m
1 stop
$726Copa Airlines
Sat, Oct 31 - Mon, Nov 9
Multiple Airlines Logo
7:30 pm - 12:15 pm
VVI
-
MAD
11h 45mnonstop
Multiple Airlines Logo
6:35 am - 2:35 am
MAD
-
VVI
25h 00m
1 stop
$993Multiple Airlines
Tue, Jul 21 - Wed, Aug 26
Air Europa Logo
12:20 pm - 5:10 am
VVI
-
MAD
10h 50mnonstop
Air Europa Logo
11:35 pm - 4:50 am
MAD
-
VVI
11h 15mnonstop
$994Air Europa
Mon, Jul 20 - Wed, Aug 26
Avianca Logo
3:35 am - 6:05 pm
VVI
-
MAD
32h 30m
2 stops
Avianca Logo
8:10 am - 2:30 am
MAD
-
VVI
24h 20m
1 stop
$999Avianca
Sun, Nov 1 - Wed, Nov 11
Multiple Airlines Logo
12:00 pm - 5:40 pm
VVI
-
LCY
25h 40m
2 stops
Multiple Airlines Logo
9:50 am - 2:35 am
LCY
-
VVI
20h 45m
2 stops
$1,373Multiple Airlines
Wed, Jul 29 - Thu, Aug 20
Multiple Airlines Logo
12:05 pm - 5:55 pm
VVI
-
LCY
24h 50m
2 stops
Multiple Airlines Logo
9:15 am - 2:30 am
LCY
-
VVI
22h 15m
2 stops
$1,427Multiple Airlines
Tue, Sep 1 - Wed, Sep 30
Multiple Airlines Logo
12:20 pm - 8:05 pm
VVI
-
BVA
25h 45m
1 stop
Multiple Airlines Logo
10:55 am - 4:50 am
BVA
-
VVI
23h 55m
2 stops
$1,870Multiple Airlines
Mon, Nov 2 - Tue, Nov 17
Multiple Airlines Logo
12:00 pm - 10:30 pm
VVI
-
HND
45h 30m
2 stops
Multiple Airlines Logo
12:05 am - 11:10 am
HND
-
VVI
48h 05m
2 stops
$2,157Multiple Airlines

Book Cheap Domestic Flights from Santa Cruz de la Sierra

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santa Cruz de la Sierra that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip domestic flight deals from Santa Cruz de la Sierra

Wed, Dec 2 - Mon, Dec 21
BoA Logo
7:35 am - 8:20 am
VVI
-
CBB
0h 45mnonstop
BoA Logo
5:20 am - 6:10 am
CBB
-
VVI
0h 50mnonstop
$123BoA
Sat, Dec 12 - Mon, Dec 21
BoA Logo
11:45 pm - 12:30 am
VVI
-
CBB
0h 45mnonstop
BoA Logo
10:25 pm - 11:15 pm
CBB
-
VVI
0h 50mnonstop
$129BoA
Sat, Aug 29 - Thu, Sep 3
BoA Logo
11:45 pm - 12:30 am
VVI
-
CBB
0h 45mnonstop
BoA Logo
10:25 pm - 11:15 pm
CBB
-
VVI
0h 50mnonstop
$133BoA
Tue, Jul 28 - Tue, Aug 4
BoA Logo
5:35 am - 6:40 am
VVI
-
LPB
1h 05mnonstop
BoA Logo
10:25 am - 11:30 am
LPB
-
VVI
1h 05mnonstop
$149BoA
Tue, Jul 28 - Tue, Aug 4
BoA Logo
5:35 am - 6:40 am
VVI
-
LPB
1h 05mnonstop
BoA Logo
10:25 am - 11:30 am
LPB
-
VVI
1h 05mnonstop
$173BoA
Fri, Sep 18 - Sun, Sep 20
BoA Logo
5:20 am - 6:25 am
VVI
-
LPB
1h 05mnonstop
BoA Logo
7:10 pm - 8:15 pm
LPB
-
VVI
1h 05mnonstop
$174BoA
Booking Insights

KAYAK's insights & trends for flights from Santa Cruz de la Sierra

Get data-powered insights and trends into flights from Santa Cruz de la Sierra to help you find the cheapest flights, the best time to fly and much more.

Which are the most popular places to fly to from Santa Cruz de la Sierra?

The domestic destinations KAYAK users have most searched for when searching for flights from Santa Cruz de la Sierra.

Based on KAYAK flight searches, the most popular place to fly from Santa Cruz de la Sierra is Cochabamba J Wilsterman (71% of total searches).

What are the most popular international flights out of Santa Cruz de la Sierra?

The international destinations KAYAK users have most searched for when searching for flights from Santa Cruz de la Sierra.

There are many international destinations you can fly to from Santa Cruz de la Sierra. The most popular international destinations among KAYAK users are Miami, Washington, D.C. and New York.

What are the most popular countries to fly to from Santa Cruz de la Sierra?

The most popular countries KAYAK users have searched for from Santa Cruz de la Sierra along with the average round-trip price for the route clicked by KAYAK users in the last 2 weeks.

Based on KAYAK flight searches, the most popular country to fly to from Santa Cruz de la Sierra is Panama (39% of total searches). The next most popular destinations are Colombia (24%) and Peru (8%).

What is the longest direct flight from Santa Cruz de la Sierra?

The longest direct flight you can take from Santa Cruz de la Sierra is to Madrid, with a duration of 10h 45m. The next longest is Miami at 6h 50m, followed by a flight to Panama City at 4h 52m.

Good to know

Low seasonFebruary
Cheapest flight$383
Best time to beat the crowds with an average 4% drop in price.
Most popular time to fly and prices are also 4% lower on average.
Flight from Santa Cruz de la Sierra to Fort Lauderdale

FAQs for booking flights out of Santa Cruz de la Sierra

  • What is Santa Cruz de la Sierra also known as?

    Santa Cruz de la Sierra Viru Viru Intl Airport’s airport code is VVI. It can also be referred to as Viru Viru Intl.

  • How does KAYAK find such low prices on flights from Santa Cruz de la Sierra?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Santa Cruz de la Sierra.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Santa Cruz de la Sierra?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Santa Cruz de la Sierra is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Santa Cruz de la Sierra?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to your destination with an airline and back to Santa Cruz de la Sierra with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Santa Cruz de la Sierra?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Santa Cruz de la Sierra up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Top tips for finding a cheap flight out of Santa Cruz de la Sierra

  • Looking for a cheap flight? 25% of our users found tickets from Santa Cruz de la Sierra to the following destinations at these prices or less: Bogotá $410 one-way - $595 round-trip; La Paz $122 one-way - $307 round-trip; Panama City $504 one-way - $688 round-trip

Reviews of the top 5 airlines serving from Santa Cruz de la Sierra to Worldwide

 
Need help choosing which airline to fly with from Santa Cruz de la Sierra to Worldwide? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.6
Copa AirlinesOverall score based on 1567 reviews
7.4Comfort
6.8Entertainment
6.9Food
7.8Boarding
8.1Crew
Airline reviews

Same as the previous flight as far as comfort and food. Entertainment didn’t have a watchable screen so everything would need to be watched on your own device in which they didn’t have a charging port that accommodated my iPhone. Seats were very uncomfortable. Staff was very friendly.

6.0 GoodAnonymous, May 2026
PTY - LAX
Read more Copa Airlines reviews

Same as the previous flight as far as comfort and food. Entertainment didn’t have a watchable screen so everything would need to be watched on your own device in which they didn’t have a charging port that accommodated my iPhone. Seats were very uncomfortable. Staff was very friendly.

They didn’t have any headphones for the entertainment screen and their USB port didn’t accommodate a USB-C for more modern phones. The food was just ok. The staff was friendly but the seats were very uncomfortable for a full flight.

Boarding was a mess, they call all priority members without distinction so gold, platinum, silver were all mixed together in a long line which defeats the purpose

Cops Airlines is fantastic! The level of care and professionalism provided by the entire crew was top rate.

Had to go through security at the gate again. Had to take off shoes and go through the whole thing again even though we have global entry. They asked us to check in items bought at duty free during our layover and since we checked our luggage at the original departure airport, they forced us to check in a small backpack. None of this ever happened with other airlines. In addition, no vegetarian food option and no snacks during a 7 hr flight. Luggage limits are unusually small. This is unacceptable. Will NEVER fly Copa again and will tell friends and family to avoid this airline.

Tell people to remain in their seats during the meal/beverage distribution. Enforce boarding by group numbers. No one was checking. Tell people to turn their electronics speakers off. Bigger cups for drinks.

Just a minor inconvinient with weather delay! but not Copa's fault

Copa is one of the airlines with the best prices and super good service.

Captain and Crew were excellent. The Boeing 737-800 was showing its age. In flight entertainment system was sluggish and my Business Class seat on the outbound flight had some mechanical issues. Only real problem was the location of the Gate in Panama PTY. It was a 40 minute hike from Security to the Gate. There should have been some sort of warning about the distance.

la atencion en el avion fue excelente, la facilidad del checkin es muy buena.

LATAM’s crews are fine, but God help you if you need any customer service. Their app and website never work, with error after error. Trying to solve anything over the phone is painful, and lastly, the boarding pass LATAM gave me to board the flight with Delta was invalid and I had to purchase an emergency one-way ticket at the last minute to get home.

Check in -- in business took over 30 mins as there was only one attendant. Boarding was also a mess. The seat was too narrow and was not working properly. Food was very bad and the entertainment very poor. Crew was very polite and helpful, in fairness.

My biggest complaint is the comfort. I am not tall and there was no legroom. It was very uncomfortable. During my transfer in Sao Paola, the flight was slightly delayed so boarding was confusing because there were no instructions in English.

We didn’t have any entertainment. I tried to go online without success. The airplane was extremely cold and they didn’t have blankets.

The Flight was delayed in 2,5 hours. 1 hour inside the airplane then we passangers were not allowed to receive food as the local regulariam determines (for delays bigger than 2 hours)

For bus boarding, group 1 should have been sent on a separate bus ahead of the general boarding. It would have been nice.

TAM is a real disappointment. We had to jump on a crowded bus for a 6am flight - although there were at least 15 available fingers that could have been used by our plane. Then, we were placed on row 30 - the last row of the plane, despite having purchased the tickets a long time ago and being TAM gold plus members. Note: worse seats on the plane. Great way of rewarding your frequent flyers TAM ! I now remember why I stoped flying internationally with TAM and moved to American, United, Swiss, Lufthansa and BA. TAM has no respect for its customers.

Not very good, they nickel & dime you for better seats & pay extra for the checking in bag, bad service all the way around

Hostile flight attendants. Second flight with Jose so much better. Arrived 1/2 hour early. Thanks.

As usual, LATAM tried to rip me off as a Gringo. They ignored the fact that having paid for my assigned seats, I was entitled to one free luggage per person, up to 10kg, and tried to charge me USD40 per item. While they ripped me off by $160 on my outbound flight (4 luggage pieces, which should have been free), I vehemently protested this time around. Note that they only request this from gringos, not from Spanish speakers. LATAM behaves like a racist extortion organization.

Was given all 3 boarding passes. Was refused boarding to Brasilia in Miami even though I had up to date Brazilian Visa and US passport. Had to return to Phoenix as trip was cancelled. Waiting for refund of the fare. Missed my son's birthday and visit with him and his wife.

The check in and on the ground experience is very poor. Their online check and trip management is the worst I have ever seen and they have long lines to check in at the airport, technology is glitchy/unusable and have exorbitant baggage fees. The flight itself is fine, although the food is about what you would expect and their was no functioning entertainment for an international flight.

Overall it was good. The food was not great quality and seats were very uncomfortable. But overall the staff was very friendly and helpful.

I did not like the way that baggage fees were charged. When I signed up for the flight, I knew that there were bag fees. However, the bag fees were so confusing that it felt like I was paying for overweight bags rather than just for having brought a bag with me. Also, the bag fees were based on the pair of tickets rather than per person. It seems to me that it should be first bag fee for passenger 1 and then first bag fee for passenger 2. I eventually got away with only paying $100 for two bags, but it was a struggle to understand the process. As for the flight, the seats were the standard uncomfortable seats that are on most Boeing aircraft. The airline aims to accommodate the standard height people, so us tall people are stuck. There was never an option to upgrade for leg room. It did not appear that there were any seats on the whole plane that had a little more leg room to even try to get. Other than that, I completely ignored the food for this red eye flight. I am not one to eat "dinner" at 2 am. They did not offer any drinks in the morning before landing. I recommend that you bring a bottle of water on board.

Gol has an interesting choice of words. When they say “priority access”, this means you’re boarding on the seventh or eighth group.

Well organized boarding, de- boarding from both ends of plane, friendly and helpful staff. Unfortunately the departure was 90 minutes late.

Obviously it would be better if we had screens available.

A Gol precisa aprender comfazer desembarque. Está anos luz atrás em organização. Os comissários são muito atrapalhados.

Too much delay in the first two flights, so I lost the connection to the final destination.

Cabin was extremely hot - such a sauna, and all complaints were in vain. Boarding was messy and disorganized. Very poor experience and certainly a statement of how passengers are going to suffer in Brazil with the lack of competition in the local market.

Unfortunately had horrible experience Originally booked business class from La Paz to Miami Flight was delayed for 2 hours with no clear explanation

Our flight was canceled and we were put on a different flight, but we were never notified of the change until we checked in. BOA provides no beverage service during the flight and there is no in-flight entertainment. Airline staff tried to tell us that we were not allowed one personal item and one carry-on bag per person, but instead that we were only allowed one item aboard per person, which contradicts their written luggage policy. Airline staff also claimed that a car seat counted against our carry-on allowance, even though our child had his own ticket and is required to use a car seat on board per airline policy.

The crew was great, professional and polite. Good meal too. The flight was full and we departed on time out of Miami. I did feel cramped in my seat for the long overnight flight, which made it hard to sleep

This airline and their crew is so professional and kind, the trip was short and easy.

6 horas de retraso en el vuelo sin ninguna explicación por parte de la aerolínea.

Always late, the service is a sandwich, no comfort at all…

They had a problem with their air conditioning system and we almost had heat strokes because they blasted HEATED AIR for almost 40 minutes and there was literally no air. This is the worst airline in Bolivia. Can't believe we have no other options sometimes.

BOA is truly the worst airline in Bolivia. It's a shame we sometimes need to use it cause we have no more options.

This airline is always THE WORST. They seem to have flights moving to other times (late) 90% of the time. The airplanes are old, and the landing (i really don't know why) is 90% of the time shaky. I actually never buy tickets from BOA, I prefer other airlines by far.

This is one of the oldest airplanes I've ever been in. No tv, no entertainment at all, seats are SO UNCOMFORTABLE and the whole flight was so cold. It's the worst flight ever. Avoid it.

The airline did not allow enough time for the Columbia checkpoint

I actually upgraded to the medium level of seats from basic and even doing that it may have been physically the most uncomfortable flight I have ever had. They packed everyone like is a train to death camp. It was a red eye so I hoped to get some sleep but it was physically impossible to find a comfortable way to rest. I met other folks on the same flight and they said the same thing. It was an utterly miserable flight and if I have any other options I will never fly with them again

only a bag of chips and a bottle of water in business class was served

Very uncomfortable planes , poor service on the plane , take your own water so you don’t dehydrate , in a 6 hs flight they sold one time food and beverage . 1 plane was delayed 6 hs , I lost a connecting flight . Then in the way back they announce a delay of 2 hs so I had to take a different flight to arrive on time for my connecting flight . Avoid this airline .

Purchased a business class ticket and got a economy seat with center seat blocked they call it business. 3100usd ticket on a flight where economy costs 500usd The biggest scam insult have had on a regular airline. Avianca should be in the low cost category and kicked out of Star Alliance. I want the difference to be credited. Ets see what Avianca does. No reply so far. Avianca = low cost airline. Beware

I paid over $200 for seat selection for these flights and I was still stuck on long international flights in seats that do not recline and do not have the head support cushion. At this point basically all airlines have those for all seats, and this really took me by surprise and made me not ever want to travel on Avianca. The Kayak agent who called me for the seat selection (Donovan) was courteous, but it seems the system for this doesn't work. I was offered seat selection, for the $200+, but without being able to see what I was selecting, with no guarantee where I'd be...and then I still ended up in terrible seats. On my way to, and especially after, a very intense business trip, the seat situation really soured my experience.

The good thing is the flight was on time and the crew was really nice. They can work better the arriving with staff

Avianca flights to Galapagos and back and well organized and on time.

Boarding was very expedite. The chairs are fixed you can't rest comfortable during the flight.

The temperature was cold and the food that we had to pay for was awful. The crew didn’t even offer a free glass of water. It was a long, expensive and uncomfortable flight.

Everything you need to know for your flight from Santa Cruz de la Sierra

Information on your arrival and departure airports