$377 Find Deals on Flights from Santa Cruz de la Sierra

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santa Cruz de la Sierra to Worldwide departing on 5/16. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find Cheap Flights from Santa Cruz de la Sierra

Where can I fly from Santa Cruz de la Sierra?Prices from VVI, departing Fri 6/5 and returning Fri 6/12

Book Cheap International Flights from Santa Cruz de la Sierra

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santa Cruz de la Sierra that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip international flight deals from Santa Cruz de la Sierra to anywhere

Mon, Sep 21 - Sun, Sep 27
LATAM Airlines Logo
5:25 am - 2:20 pm
VVI
-
CUN
9h 55m
1 stop
LATAM Airlines Logo
6:45 pm - 4:35 am
CUN
-
VVI
8h 50m
1 stop
$752LATAM Airlines
Sat, Aug 1 - Sat, Aug 8
Copa Airlines Logo
1:12 am - 9:58 pm
VVI
-
CUN
21h 46m
1 stop
Copa Airlines Logo
7:01 am - 10:40 pm
CUN
-
VVI
14h 39m
1 stop
$759Copa Airlines
Thu, Sep 17 - Sun, Sep 27
Copa Airlines Logo
1:12 am - 1:01 pm
VVI
-
CUN
12h 49m
1 stop
Copa Airlines Logo
7:01 am - 10:44 pm
CUN
-
VVI
14h 43m
1 stop
$770Copa Airlines
Tue, Oct 27 - Wed, Nov 4
Iberia Logo
7:30 pm - 12:15 pm
VVI
-
MAD
11h 45mnonstop
Iberia Logo
2:45 pm - 7:45 pm
MAD
-
VVI
10h 00mnonstop
$844Iberia
Thu, Oct 8 - Mon, Oct 12
Air Europa Logo
12:20 pm - 5:10 am
VVI
-
MAD
10h 50mnonstop
Air Europa Logo
11:35 pm - 4:50 am
MAD
-
VVI
11h 15mnonstop
$898Air Europa
Thu, Jul 2 - Sun, Aug 30
Air Europa Logo
12:20 pm - 5:10 am
VVI
-
MAD
10h 50mnonstop
Air Europa Logo
11:35 pm - 4:50 am
MAD
-
VVI
11h 15mnonstop
$903Air Europa
Wed, May 27 - Thu, Jun 11
Avianca Logo
3:35 am - 8:45 am
VVI
-
BCN
23h 10m
1 stop
Avianca Logo
3:40 pm - 2:30 am
BCN
-
VVI
16h 50m
1 stop
$1,385Avianca
Sun, May 17 - Fri, May 22
Avianca Logo
3:35 am - 8:45 am
VVI
-
BCN
23h 10m
1 stop
Avianca Logo
1:50 pm - 2:30 am
BCN
-
VVI
18h 40m
1 stop
$1,419Avianca
Fri, Jul 3 - Fri, Jul 10
Avianca Logo
3:35 am - 1:40 pm
VVI
-
BCN
28h 05m
1 stop
Avianca Logo
1:50 pm - 2:30 am
BCN
-
VVI
18h 40m
1 stop
$1,499Avianca
Wed, May 20 - Sun, Jun 14
Multiple Airlines Logo
3:35 am - 1:10 pm
VVI
-
BVA
27h 35m
2 stops
Multiple Airlines Logo
9:25 am - 2:30 am
BVA
-
VVI
47h 05m
3 stops
$1,595Multiple Airlines

Book Cheap Domestic Flights from Santa Cruz de la Sierra

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santa Cruz de la Sierra that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip domestic flight deals from Santa Cruz de la Sierra

Tue, Jun 9 - Thu, Jun 11
BoA Logo
10:45 pm - 11:30 pm
VVI
-
CBB
0h 45mnonstop
BoA Logo
10:30 pm - 11:20 pm
CBB
-
VVI
0h 50mnonstop
$79BoA
Thu, Jun 18 - Sat, Jun 20
BoA Logo
12:45 pm - 1:30 pm
VVI
-
CBB
0h 45mnonstop
BoA Logo
10:30 pm - 11:20 pm
CBB
-
VVI
0h 50mnonstop
$88BoA
Tue, Jun 9 - Thu, Jun 11
BoA Logo
4:50 pm - 9:40 pm
VVI
-
CBB
4h 50m
1 stop
BoA Logo
11:20 am - 12:10 pm
CBB
-
VVI
0h 50mnonstop
$106BoA
Thu, Jun 4 - Mon, Jun 8
BoA Logo
9:10 pm - 11:25 pm
VVI
-
LPB
2h 15m
1 stop
BoA Logo
11:35 pm - 6:35 am
LPB
-
VVI
7h 00m
1 stop
$117BoA
Thu, Jun 4 - Mon, Jun 8
BoA Logo
5:35 am - 6:40 am
VVI
-
LPB
1h 05mnonstop
BoA Logo
11:35 pm - 6:35 am
LPB
-
VVI
7h 00m
1 stop
$128BoA
Wed, Jun 3 - Wed, Jun 10
BoA Logo
5:35 am - 2:15 pm
VVI
-
LPB
8h 40m
1 stop
BoA Logo
12:05 pm - 7:00 pm
LPB
-
VVI
6h 55m
1 stop
$134BoA
Booking Insights

KAYAK's insights & trends for flights from Santa Cruz de la Sierra

Get data-powered insights and trends into flights from Santa Cruz de la Sierra to help you find the cheapest flights, the best time to fly and much more.

Which are the most popular places to fly to from Santa Cruz de la Sierra?

The domestic destinations KAYAK users have most searched for when searching for flights from Santa Cruz de la Sierra.

Based on KAYAK flight searches, the most popular place to fly from Santa Cruz de la Sierra is Cochabamba J Wilsterman (71% of total searches).

What are the most popular international flights out of Santa Cruz de la Sierra?

The international destinations KAYAK users have most searched for when searching for flights from Santa Cruz de la Sierra.

There are many international destinations you can fly to from Santa Cruz de la Sierra. The most popular international destinations among KAYAK users are Madrid, Dallas and Fort Lauderdale.

What are the most popular countries to fly to from Santa Cruz de la Sierra?

The most popular countries KAYAK users have searched for from Santa Cruz de la Sierra along with the average round-trip price for the route clicked by KAYAK users in the last 2 weeks.

Based on KAYAK flight searches, the most popular country to fly to from Santa Cruz de la Sierra is Panama (36% of total searches). The next most popular destinations are Colombia (26%) and United States (16%).

Good to know

Low seasonFebruary
Cheapest flight$377
Best time to beat the crowds but there is an average 4% increase in price.
Most popular time to fly with an average 3% increase in price.
Flight from Santa Cruz de la Sierra to Mexico City

FAQs for booking flights out of Santa Cruz de la Sierra

  • What is Santa Cruz de la Sierra also known as?

    Santa Cruz de la Sierra Viru Viru Intl Airport’s airport code is VVI. It can also be referred to as Viru Viru Intl.

  • How does KAYAK find such low prices on flights from Santa Cruz de la Sierra?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Santa Cruz de la Sierra.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Santa Cruz de la Sierra?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Santa Cruz de la Sierra is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Santa Cruz de la Sierra?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to your destination with an airline and back to Santa Cruz de la Sierra with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Santa Cruz de la Sierra?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Santa Cruz de la Sierra up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Top tips for finding a cheap flight out of Santa Cruz de la Sierra

  • Looking for a cheap flight? 25% of our users found tickets from Santa Cruz de la Sierra to the following destinations at these prices or less: Bogotá $399 one-way - $671 round-trip; Miami $397 one-way - $648 round-trip; Panama City $401 one-way - $860 round-trip

Reviews of the top 5 airlines serving from Santa Cruz de la Sierra to Worldwide

 
Need help choosing which airline to fly with from Santa Cruz de la Sierra to Worldwide? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
Copa AirlinesOverall score based on 1580 reviews
7.8Boarding
7.4Comfort
6.8Food
6.8Entertainment
8.1Crew
Airline reviews

I had to run from the end of terminal one to the end of terminal two to make the connecting flight....probably a kilometer. No electric carts were available. I'm 76 and literally had to run to make the connection at the last minute. The connecting time was absolutely unrealistic. When Last Call was announced, I tried to get other Copa gate staff to call Gate 221 to let them know I was on my way, but they said no. I came within 1 minute of missing the flight.

2.0 MediocreFred, May 2026
UIO - PTY
Read more Copa Airlines reviews

I had to run from the end of terminal one to the end of terminal two to make the connecting flight....probably a kilometer. No electric carts were available. I'm 76 and literally had to run to make the connection at the last minute. The connecting time was absolutely unrealistic. When Last Call was announced, I tried to get other Copa gate staff to call Gate 221 to let them know I was on my way, but they said no. I came within 1 minute of missing the flight.

Boarding was a mess, they call all priority members without distinction so gold, platinum, silver were all mixed together in a long line which defeats the purpose

Avoid at all costs. My wife had to stay back on a connecting flight as her parents flight was delayed. 10 days later on the way back they cancelled all our flights. We had to rebook all four of us on the next days flight.

The food is terrible I ask for water never got transport my mother we’re late and my sister from Lima was the worst waiting to long for wheelchair

A lot things happened in this trip.The fly should be less stress.

There should be a warning regarding the quality of the aircraft on the website as we reserve the tickets. There was no TV or any type of screen onboard. The wifi they offer is good for nothing. Traveling 9 hours straight with kids and no type of entetainment was horrible. I wish I had been informed prior so I could buy a ticket with another airline. The food was a joke too. A very tiny portion per passenger. They also charged $100 per checked bag. With United I used to pay $60. So, fair to say that I wont be flying Copa anymore. Their aircraft was super old, outdated, no entertainment, with nearly no onboard food.

I always enjoy flying Copa. There are very few airlines where I can enjoy a comfortable sleep in-flight. The snacks weren't the best, but they sufficed. The in-flight entertainment was fantastic, and I crossed another movie off my watch list.

Some of the Air hostesses are not that friendly. Need improvement

Simply as follows:- First, there was no vegetarian option for the meal Second, only 2 washrooms for the entire economy class.

Boarding was quick & efficient; they gave boarding groups due priority; staff & air crew were very cordial and helpful, pleasant flight.

We liked the way we were treated by the sraff at lima airport counter and the the flight attendants. We did not like the fact that the kiosks at airport rebooted after we entered our information and then told us that there was an issueand we needed to go to the counter. Such a waste of time for a group of 6. Once we got our boarding passes there was no assigned gate so we did not know where to go.

Nothing I like, I missed this connection b/c of an earlier flight delay. I had to stay one more night and I paid out my own pocket. LATAM failed to send me to a safe and decent hotel.

LATAM is a great airline who takes care of there guests. They consistently walk around and see if you need water in addition to taking care of all the passengers. The chicken in process is really easy and I’m always offered a chance for an upgrade which I appreciate.

Good check in process Poor information on payments at Lima airport

There was a mechanical issue with the plane that they had to work on before we could take off. That's fine, by all means, PLEASE make sure the mechanics are functioning properly. What was a problem was the fact that we sat on the tarmac for 4.5 hours without moving, without letting us off the plane, and without climate control and air running through the plane. There was no explanation as to what was going on; they just kept promising that it would be "15 minutes, then we are on our way." At one point, they even switched the entire crew out and told everyone we just needed to wait for new employees to show up. Then, as the 4 hours were not moving, an hour before the full refund, they made a big show about "the flight starting and the doors are locked, so you have to sit down." We didn't move for another 40 minutes; they were just trying to skirt around legalities that entitled us to restitution. When the flight finally was underway, the plane was gigantic but cramped in design, my entertainment screen kept freezing and glitching, and subtitles didn't work, and the crew was passive-aggressive. Terrible flight.

LATAM’s crews are fine, but God help you if you need any customer service. Their app and website never work, with error after error. Trying to solve anything over the phone is painful, and lastly, the boarding pass LATAM gave me to board the flight with Delta was invalid and I had to purchase an emergency one-way ticket at the last minute to get home.

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

Wish the seats were a little more comfortable.. it was a 6 hrs nonstop trip. But the crew was courteous and w a smile

The assistance we received and the flight itself was wonderful. We will fly with LATAM airlines again, in the future.

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

Was given all 3 boarding passes. Was refused boarding to Brasilia in Miami even though I had up to date Brazilian Visa and US passport. Had to return to Phoenix as trip was cancelled. Waiting for refund of the fare. Missed my son's birthday and visit with him and his wife.

The pilots landing and taking off was very bad on the first flight, the second one taking off was great but landing was also rough

The check in and on the ground experience is very poor. Their online check and trip management is the worst I have ever seen and they have long lines to check in at the airport, technology is glitchy/unusable and have exorbitant baggage fees. The flight itself is fine, although the food is about what you would expect and their was no functioning entertainment for an international flight.

My experience with this flight was extremely negative and resulted in serious financial and personal consequences. The flight departed with a significant delay, which caused me to miss my international connecting flight. As a direct result of this delay — which was entirely beyond my control — I was unable to reach my final destination on time, causing me to lose a previously scheduled hair transplant surgery that had been arranged months in advance. This was not a minor inconvenience. The surgery involved: • A reserved operating room • Medical and technical staff scheduled specifically for that date • Surgical instruments prepared in advance • Strict scheduling that does not allow for easy rescheduling Due to the airline’s delay and poor handling of the situation: • I lost already paid international flight tickets • I was forced to purchase new tickets, incurring duplicate expenses • I spent over six additional hours in airports, under stressful conditions • I incurred unexpected costs for meals and transportation • I lost a medical opportunity that cannot be easily recovered, along with the emotional distress associated with it Although the airline covered one night of hotel accommodation, this did not address the real impact of the delay, nor the significant damages caused by missing a critical medical procedure. The lack of punctuality, planning, and effective solutions reflects a serious lack of responsibility toward passengers, especially when international connections and time-sensitive medical commitments are involved. I do not recommend this airline for travelers with important schedules, medical appointments, or critical connections. In my case, the delay did not merely cause inconvenience — it resulted in the loss of a surgery and substantial financial damage.

I was not able to get on the flight due to delays out of Philadelphia. I arrived in MIA at 10:30pm and there was no one at the GOL Desk. Is there any flight credit available for this flight?

I have a hand injury and the flight attendant denied to help me with luggage, she said "she couldn't help me because I should manage my own way to put the luggage on the plane" SO RUDE

I had two around 6 hours flight and they did not even offer water to us.

Overall it was good. The food was not great quality and seats were very uncomfortable. But overall the staff was very friendly and helpful.

We flew with Avianca, some how they are not n sync, making the process a bit uncomfortable.

Unfortunately it was very disappointed experience. Our first flight our was delayed 2 hours, as a consequence we missed our connecting international flight. Customer server at Miami American Airlines was very disrespectful, gave us the worst replace itenarary for the next day that we had to spend 2 hours calling Gol to get a better itinerary otherwise we wouldn't make it on time to fulfill our trip purpose. We would have missed the reason to travel all the way to Brazil if we didn't change for a better itinerary. The worst thing is that our baggage was missing for 4 days. We had no cloths for all this time, plus the aggravation to locate our baggage. Nobody knew where our baggage was. We ended up picking it up at the airport when they said that they will bring them home. Unfortunately our experience was very dissatisfied.

Unfortunately had horrible experience Originally booked business class from La Paz to Miami Flight was delayed for 2 hours with no clear explanation

Our flight was canceled and we were put on a different flight, but we were never notified of the change until we checked in. BOA provides no beverage service during the flight and there is no in-flight entertainment. Airline staff tried to tell us that we were not allowed one personal item and one carry-on bag per person, but instead that we were only allowed one item aboard per person, which contradicts their written luggage policy. Airline staff also claimed that a car seat counted against our carry-on allowance, even though our child had his own ticket and is required to use a car seat on board per airline policy.

The crew was great, professional and polite. Good meal too. The flight was full and we departed on time out of Miami. I did feel cramped in my seat for the long overnight flight, which made it hard to sleep

This airline and their crew is so professional and kind, the trip was short and easy.

It was a very smooth process. Everything about the Airline like a well oiled machine.

Muy horrible experiencia, cambiaron dos veces la hora del vuelo resultando en una espera exagerada. No dan información oportuna. Abordadnos el avión retrasado el vuelo y esperamos dentro del avión por 35’ más mientras subían como 6 carros de cajas al avión. Muy mala logística y servicio.

6 horas de retraso en el vuelo sin ninguna explicación por parte de la aerolínea.

Always late, the service is a sandwich, no comfort at all…

They had a problem with their air conditioning system and we almost had heat strokes because they blasted HEATED AIR for almost 40 minutes and there was literally no air. This is the worst airline in Bolivia. Can't believe we have no other options sometimes.

BOA is truly the worst airline in Bolivia. It's a shame we sometimes need to use it cause we have no more options.

The crew was great! They waited for me as Air Canada flight was delayed by 1:15 hours from Ottawa to Toronto. I am a bit disappointed that we could only use wifi for entertainment but I survived! The only thing I would of liked is a more comfortable seat. The seat cushions are not thick enough for flights longer than 3 hours. Aside from that, everything was great.

After boarding, there was a small issue with the aircraft which caused a delay of about 45 minutes. During boarding and while passengers were being seated, the plane was being refueled. There were also a lot of unusual noises during the flight, which was not very reassuring. In addition, there was no WiFi or entertainment available.

I upgraded to businesses class. Because of that the flight was comfortable.

only a bag of chips and a bottle of water in business class was served

Avianca has transitioned from full service legacy airline to "low cost" but has now became a strange hybrid (minimum leg space, started offering business class in domestic flights again, charges passenger for printing boarding pass, etc.). National and international coverage and destinations are really wide but service is not at its best

We found the chairs to be really uncomfortable. It’s also really unacceptable that no form of food or drink is included in a 6+ hour flight

Not good, tried to purchase a first class upgrade and they couldn’t get it done. Was super uncomfortable the whole time.

Here we have another airline flying to Guatemala but doesn't have a plus or a less, just in the middle. Why? Well, first we don't have even free water Movie selection is poor Seats don't recline in some places Food selection is carb based Forgot to mention, customer service on the web is the worst. Good things; Very reliable on schedule Kind crew

I had to go to the boarding counter for them to enter my return flight as it’s not with Avianca. There was a long queue as there were lots of people being called to the counter.

Usb plugs for charging your phone does not work in every flight. uncomfortable chairs even in higher categories.

Everything you need to know for your flight from Santa Cruz de la Sierra

Information on your arrival and departure airports