$234 Find Deals on Flights from Santa Cruz de la Sierra

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santa Cruz de la Sierra to Worldwide departing on 2/21. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for cheap international flights from Santa Cruz de la Sierra

Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 23% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Free to useThere are no hidden charges or fees.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Flight Deals
Booking Insights
Flight Deals

Find Cheap Flights from Santa Cruz de la Sierra

Where can I fly from Santa Cruz de la Sierra?Prices from VVI, departing Fri 3/6 and returning Fri 3/13

Book Cheap International Flights from Santa Cruz de la Sierra

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santa Cruz de la Sierra that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip international flight deals from Santa Cruz de la Sierra to anywhere

Sat, Apr 4 - Fri, Apr 10
Copa Airlines Logo
11:48 am - 10:00 pm
VVI
-
CUN
11h 12m
1 stop
Copa Airlines Logo
11:37 am - 10:42 pm
CUN
-
VVI
10h 05m
1 stop
$580Copa Airlines
Thu, Mar 5 - Wed, Mar 18
Avianca Logo
3:40 am - 11:35 am
VVI
-
CUN
8h 55m
1 stop
Avianca Logo
4:50 pm - 2:35 am
CUN
-
VVI
8h 45m
1 stop
$631Avianca
Tue, Feb 24 - Wed, Mar 4
Avianca Logo
3:40 am - 3:50 pm
VVI
-
CUN
13h 10m
1 stop
Avianca Logo
12:35 pm - 2:35 am
CUN
-
VVI
13h 00m
1 stop
$675Avianca
Mon, Jun 22 - Wed, Aug 19
Iberia Logo
9:15 pm - 1:55 pm
VVI
-
MAD
10h 40mnonstop
Iberia Logo
2:40 pm - 7:40 pm
MAD
-
VVI
11h 00mnonstop
$845Iberia
Thu, May 7 - Fri, May 29
Air Europa Logo
12:20 pm - 5:10 am
VVI
-
MAD
10h 50mnonstop
Air Europa Logo
2:50 am - 8:05 am
MAD
-
VVI
11h 15mnonstop
$910Air Europa
Tue, May 5 - Wed, May 13
Air Europa Logo
12:20 pm - 5:10 am
VVI
-
MAD
10h 50mnonstop
Air Europa Logo
11:35 pm - 4:50 am
MAD
-
VVI
11h 15mnonstop
$950Air Europa
Tue, May 12 - Sun, May 31
Iberia Logo
6:50 pm - 10:50 pm
VVI
-
BCN
22h 00m
1 stop
Iberia Logo
2:50 pm - 2:30 am
BCN
-
VVI
17h 40m
1 stop
$1,117Iberia
Wed, Jun 10 - Wed, Sep 2
Multiple Airlines Logo
9:05 am - 9:40 am
VVI
-
BCN
18h 35m
1 stop
Multiple Airlines Logo
1:10 pm - 3:50 pm
BCN
-
VVI
32h 40m
1 stop
$1,143Multiple Airlines
Fri, Apr 24 - Sun, May 31
Avianca Logo
3:35 am - 8:45 am
VVI
-
BCN
23h 10m
1 stop
Avianca Logo
1:50 pm - 2:30 am
BCN
-
VVI
18h 40m
1 stop
$1,168Avianca
Sun, May 24 - Thu, Jun 11
Multiple Airlines Logo
12:00 pm - 5:55 pm
VVI
-
LCY
24h 55m
2 stops
Multiple Airlines Logo
6:30 pm - 11:10 am
LCY
-
VVI
21h 40m
2 stops
$1,809Multiple Airlines

Book Cheap Domestic Flights from Santa Cruz de la Sierra

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santa Cruz de la Sierra that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip domestic flight deals from Santa Cruz de la Sierra

Mon, Mar 2 - Mon, Mar 9
BoA Logo
5:25 pm - 6:10 pm
VVI
-
CBB
0h 45mnonstop
BoA Logo
9:10 am - 10:00 am
CBB
-
VVI
0h 50mnonstop
$113BoA
Sat, Feb 21 - Mon, Feb 23
BoA Logo
5:25 pm - 6:10 pm
VVI
-
CBB
0h 45mnonstop
BoA Logo
10:00 pm - 10:50 pm
CBB
-
VVI
0h 50mnonstop
$114BoA
Sun, Feb 15 - Fri, Feb 27
BoA Logo
5:25 pm - 6:10 pm
VVI
-
CBB
0h 45mnonstop
BoA Logo
12:05 pm - 12:55 pm
CBB
-
VVI
0h 50mnonstop
$126BoA
Tue, Mar 3 - Tue, Mar 10
BoA Logo
5:20 am - 6:25 am
VVI
-
LPB
1h 05mnonstop
BoA Logo
9:15 am - 10:20 am
LPB
-
VVI
1h 05mnonstop
$171BoA
Wed, Mar 4 - Thu, Mar 5
BoA Logo
5:35 am - 7:55 am
VVI
-
LPB
2h 20m
1 stop
BoA Logo
5:45 am - 7:50 am
LPB
-
VVI
2h 05m
1 stop
$175BoA
Thu, Mar 19 - Thu, Mar 26
BoA Logo
11:25 pm - 6:45 am
VVI
-
LPB
7h 20m
1 stop
BoA Logo
5:45 am - 10:00 am
LPB
-
VVI
4h 15m
1 stop
$176BoA
Booking Insights

KAYAK's insights & trends for flights from Santa Cruz de la Sierra

Get data-powered insights and trends into flights from Santa Cruz de la Sierra to help you find the cheapest flights, the best time to fly and much more.

Which are the most popular places to fly to from Santa Cruz de la Sierra?

The domestic destinations KAYAK users have most searched for when searching for flights from Santa Cruz de la Sierra.

Based on KAYAK flight searches, the most popular place to fly from Santa Cruz de la Sierra is Cochabamba J Wilsterman (71% of total searches).

What are the most popular international flights out of Santa Cruz de la Sierra?

The international destinations KAYAK users have most searched for when searching for flights from Santa Cruz de la Sierra.

There are many international destinations you can fly to from Santa Cruz de la Sierra. The most popular international destinations among KAYAK users are Houston, Buenos Aires and Fort Lauderdale.

What are the most popular countries to fly to from Santa Cruz de la Sierra?

The most popular countries KAYAK users have searched for from Santa Cruz de la Sierra along with the average round-trip price for the route clicked by KAYAK users in the last 2 weeks.

Based on KAYAK flight searches, the most popular country to fly to from Santa Cruz de la Sierra is Panama (34% of total searches). The next most popular destinations are Colombia (24%) and Brazil (15%).

What is the longest direct flight from Santa Cruz de la Sierra?

The longest direct flight you can take from Santa Cruz de la Sierra is to Madrid, with a duration of 10h 50m. The next longest is Miami at 6h 50m, followed by a flight to Panama City at 4h 49m.

Good to know

Low seasonOctober
Cheapest flight$234
Best time to beat the crowds with an average 17% drop in price.
Most popular time to fly with an average 2% increase in price.
Flight from Santa Cruz de la Sierra to Buenos Aires Ministro Pistarini

FAQs for booking flights out of Santa Cruz de la Sierra

  • What is Santa Cruz de la Sierra also known as?

    Santa Cruz de la Sierra Viru Viru Intl Airport’s airport code is VVI. It can also be referred to as Viru Viru Intl.

  • How does KAYAK find such low prices on flights from Santa Cruz de la Sierra?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Santa Cruz de la Sierra.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Santa Cruz de la Sierra?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Santa Cruz de la Sierra is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Santa Cruz de la Sierra?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to your destination with an airline and back to Santa Cruz de la Sierra with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Santa Cruz de la Sierra?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Santa Cruz de la Sierra up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Top tips for finding a cheap flight out of Santa Cruz de la Sierra

  • Looking for a cheap flight? 25% of our users found tickets from Santa Cruz de la Sierra to the following destinations at these prices or less: Bogotá $493 one-way - $685 round-trip; Sao Paulo $276 one-way - $449 round-trip; Panama City $408 one-way - $630 round-trip

Reviews of the top 5 airlines serving from Santa Cruz de la Sierra to Worldwide

 
Need help choosing which airline to fly with from Santa Cruz de la Sierra to Worldwide? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
LATAM AirlinesOverall score based on 1918 reviews
7.5Boarding
6.7Food
7.0Entertainment
7.3Comfort
8.0Crew
Airline reviews

Apart of Sky miles delta. And they go everywhere in Brazil

10.0 ExcellentAnonymous, Feb 2026
MCO - GRU
Read more LATAM Airlines reviews

Apart of Sky miles delta. And they go everywhere in Brazil

Latam wouldn’t tell me how much checked luggage would until I was at the airport and they charged me the highest price possible. Besides that, it was okay.

There was a mechanical issue with the plane that they had to work on before we could take off. That's fine, by all means, PLEASE make sure the mechanics are functioning properly. What was a problem was the fact that we sat on the tarmac for 4.5 hours without moving, without letting us off the plane, and without climate control and air running through the plane. There was no explanation as to what was going on; they just kept promising that it would be "15 minutes, then we are on our way." At one point, they even switched the entire crew out and told everyone we just needed to wait for new employees to show up. Then, as the 4 hours were not moving, an hour before the full refund, they made a big show about "the flight starting and the doors are locked, so you have to sit down." We didn't move for another 40 minutes; they were just trying to skirt around legalities that entitled us to restitution. When the flight finally was underway, the plane was gigantic but cramped in design, my entertainment screen kept freezing and glitching, and subtitles didn't work, and the crew was passive-aggressive. Terrible flight.

Comfort in exit seat was excellent. FLight crew and flight were excellent. However exit seat tray table was broken so could not use it. Entertainment monitor did not work at all despite attempts to reset it.

LATAM’s crews are fine, but God help you if you need any customer service. Their app and website never work, with error after error. Trying to solve anything over the phone is painful, and lastly, the boarding pass LATAM gave me to board the flight with Delta was invalid and I had to purchase an emergency one-way ticket at the last minute to get home.

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

Wish the seats were a little more comfortable.. it was a 6 hrs nonstop trip. But the crew was courteous and w a smile

Check in -- in business took over 30 mins as there was only one attendant. Boarding was also a mess. The seat was too narrow and was not working properly. Food was very bad and the entertainment very poor. Crew was very polite and helpful, in fairness.

we were missing our luggage, trying to find someone to have any empathy was pretty much not happening....

Seats were awful. Media should have been included for such a long flight.

A lot things happened in this trip.The fly should be less stress.

Horrible. No TV or any type of entertainment on board. Passwnger listening to/watching stuff on their own phone with no headphones making it noise and uncomfortable for everyone else, little/tiny food portions, old seats, useless wifi (cant access anything). Horrible exlerience especially it was a lomg distance flight with kids.

There should be a warning regarding the quality of the aircraft on the website as we reserve the tickets. There was no TV or any type of screen onboard. The wifi they offer is good for nothing. Traveling 9 hours straight with kids and no type of entetainment was horrible. I wish I had been informed prior so I could buy a ticket with another airline. The food was a joke too. A very tiny portion per passenger. They also charged $100 per checked bag. With United I used to pay $60. So, fair to say that I wont be flying Copa anymore. Their aircraft was super old, outdated, no entertainment, with nearly no onboard food.

The flight was good overall. Everything went smoothly, although the landing was a bit rough. Still, it was a pleasant experience

I always enjoy flying Copa. There are very few airlines where I can enjoy a comfortable sleep in-flight. The snacks weren't the best, but they sufficed. The in-flight entertainment was fantastic, and I crossed another movie off my watch list.

Very strict carry on rules meant most of the plane had to gate check their luggage. As is often the case had things that were broken because of this, but I appreciated not being charged to gate check. Otherwise good flight and great crew once on the plane

Simply as follows:- First, there was no vegetarian option for the meal Second, only 2 washrooms for the entire economy class.

I liked the meatloaf the chicken was awful but the plane was on time and got there and the staff was nice.

They were super friendly bumped me up to exit row free of charge, All flight legs were on time

The pilots landing and taking off was very bad on the first flight, the second one taking off was great but landing was also rough

The check in and on the ground experience is very poor. Their online check and trip management is the worst I have ever seen and they have long lines to check in at the airport, technology is glitchy/unusable and have exorbitant baggage fees. The flight itself is fine, although the food is about what you would expect and their was no functioning entertainment for an international flight.

My experience with this flight was extremely negative and resulted in serious financial and personal consequences. The flight departed with a significant delay, which caused me to miss my international connecting flight. As a direct result of this delay — which was entirely beyond my control — I was unable to reach my final destination on time, causing me to lose a previously scheduled hair transplant surgery that had been arranged months in advance. This was not a minor inconvenience. The surgery involved: • A reserved operating room • Medical and technical staff scheduled specifically for that date • Surgical instruments prepared in advance • Strict scheduling that does not allow for easy rescheduling Due to the airline’s delay and poor handling of the situation: • I lost already paid international flight tickets • I was forced to purchase new tickets, incurring duplicate expenses • I spent over six additional hours in airports, under stressful conditions • I incurred unexpected costs for meals and transportation • I lost a medical opportunity that cannot be easily recovered, along with the emotional distress associated with it Although the airline covered one night of hotel accommodation, this did not address the real impact of the delay, nor the significant damages caused by missing a critical medical procedure. The lack of punctuality, planning, and effective solutions reflects a serious lack of responsibility toward passengers, especially when international connections and time-sensitive medical commitments are involved. I do not recommend this airline for travelers with important schedules, medical appointments, or critical connections. In my case, the delay did not merely cause inconvenience — it resulted in the loss of a surgery and substantial financial damage.

I was not able to get on the flight due to delays out of Philadelphia. I arrived in MIA at 10:30pm and there was no one at the GOL Desk. Is there any flight credit available for this flight?

I have a hand injury and the flight attendant denied to help me with luggage, she said "she couldn't help me because I should manage my own way to put the luggage on the plane" SO RUDE

I had two around 6 hours flight and they did not even offer water to us.

Overall it was good. The food was not great quality and seats were very uncomfortable. But overall the staff was very friendly and helpful.

We flew with Avianca, some how they are not n sync, making the process a bit uncomfortable.

Unfortunately it was very disappointed experience. Our first flight our was delayed 2 hours, as a consequence we missed our connecting international flight. Customer server at Miami American Airlines was very disrespectful, gave us the worst replace itenarary for the next day that we had to spend 2 hours calling Gol to get a better itinerary otherwise we wouldn't make it on time to fulfill our trip purpose. We would have missed the reason to travel all the way to Brazil if we didn't change for a better itinerary. The worst thing is that our baggage was missing for 4 days. We had no cloths for all this time, plus the aggravation to locate our baggage. Nobody knew where our baggage was. We ended up picking it up at the airport when they said that they will bring them home. Unfortunately our experience was very dissatisfied.

Flight on time, check in and flight attendants courteous and helpful. Smaller plane for international flights, tight space, no comfortable.

Unfortunately had horrible experience Originally booked business class from La Paz to Miami Flight was delayed for 2 hours with no clear explanation

Our flight was canceled and we were put on a different flight, but we were never notified of the change until we checked in. BOA provides no beverage service during the flight and there is no in-flight entertainment. Airline staff tried to tell us that we were not allowed one personal item and one carry-on bag per person, but instead that we were only allowed one item aboard per person, which contradicts their written luggage policy. Airline staff also claimed that a car seat counted against our carry-on allowance, even though our child had his own ticket and is required to use a car seat on board per airline policy.

The crew was great, professional and polite. Good meal too. The flight was full and we departed on time out of Miami. I did feel cramped in my seat for the long overnight flight, which made it hard to sleep

This airline and their crew is so professional and kind, the trip was short and easy.

It was a very smooth process. Everything about the Airline like a well oiled machine.

Muy horrible experiencia, cambiaron dos veces la hora del vuelo resultando en una espera exagerada. No dan información oportuna. Abordadnos el avión retrasado el vuelo y esperamos dentro del avión por 35’ más mientras subían como 6 carros de cajas al avión. Muy mala logística y servicio.

6 horas de retraso en el vuelo sin ninguna explicación por parte de la aerolínea.

Always late, the service is a sandwich, no comfort at all…

They had a problem with their air conditioning system and we almost had heat strokes because they blasted HEATED AIR for almost 40 minutes and there was literally no air. This is the worst airline in Bolivia. Can't believe we have no other options sometimes.

BOA is truly the worst airline in Bolivia. It's a shame we sometimes need to use it cause we have no more options.

It was delayed and I lost my connection flight to Cali and I missed my Mom's funeral and avianca lost my check in luggage

only a bag of chips and a bottle of water in business class was served

Provide free food and drinks on an international flight. Add updated head rests

Boarding was late due to the company’s that cleaned the aircraft (very poorly done) and the catering company. The entertainment system was not working for this six hour flight, uncomfortable seats in business (barely any cushion or recline). The airline staff is very good but the planes are horrible and not well maintained.

Staff are the rudest in the industry … awful customer service … will never fly Avianca again

The flight attendant smashed her beverage cart into my knee, causing significant amount of pain. The seats were extremely uncomfortable. No food or drink is offered unless you want to pay the ridiculous prices for it. The schedule of flying in the overnight hours is also very uncomfortable.

Here we have another airline flying to Guatemala but doesn't have a plus or a less, just in the middle. Why? Well, first we don't have even free water Movie selection is poor Seats don't recline in some places Food selection is carb based Forgot to mention, customer service on the web is the worst. Good things; Very reliable on schedule Kind crew

No free snacks nor drinks on very short 30min flight. Entertainment system is over wifi to your own phone or tablet, which is good but often a show or movie just stops and refuses to continue

I had to go to the boarding counter for them to enter my return flight as it’s not with Avianca. There was a long queue as there were lots of people being called to the counter.

Usb plugs for charging your phone does not work in every flight. uncomfortable chairs even in higher categories.

Everything you need to know for your flight from Santa Cruz de la Sierra

Information on your arrival and departure airports