$543 Find Cheap Flights from Santa Fe to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santa Fe to South America departing on 10/2. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

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Cheap Flights from Santa Fe to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima2 stops$860
Santiago
Santiago2 stops$844
Lima
Lima2 stops$860
Santiago
Santiago2 stops$844

Book Cheap Santa Fe to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santa Fe to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santa Fe to South America

Sat, Dec 6 - Wed, Dec 10
United Airlines Logo
1:20 pm - 8:50 amSAF-SCL
15h 30m2 stops
United Airlines Logo
10:45 pm - 9:59 pmSCL-SAF
51h 14m2 stops
$844United Airlines
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Sat, Oct 4 - Mon, Oct 6
United Airlines Logo
5:59 pm - 11:00 pmSAF-LIM
28h 01m2 stops
United Airlines Logo
12:40 am - 10:03 pmLIM-SAF
22h 23m2 stops
$860United Airlines
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Sat, Jan 31 - Sat, Feb 14
American Airlines Logo
10:43 am - 7:50 amSAF-SCL
17h 07m1 stop
American Airlines Logo
11:15 pm - 3:43 pmSCL-SAF
20h 28m1 stop
$879American Airlines
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Sat, Jan 31 - Sat, Feb 14
United Airlines Logo
6:05 pm - 8:50 amSAF-SCL
58h 45m2 stops
United Airlines Logo
10:45 pm - 9:32 amSCL-SAF
38h 47m2 stops
$880United Airlines
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Sat, Jan 31 - Sat, Feb 14
American Airlines Logo
8:11 am - 9:05 amSAF-SCL
20h 54m2 stops
American Airlines Logo
11:15 pm - 11:04 amSCL-SAF
15h 49m1 stop
$884American Airlines
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Fri, Oct 3 - Thu, Oct 16
United Airlines Logo
5:59 pm - 11:00 pmSAF-LIM
28h 01m2 stops
United Airlines Logo
12:40 am - 9:24 amLIM-SAF
33h 44m2 stops
$931United Airlines
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Sat, Dec 6 - Wed, Dec 10
American Airlines Logo
10:40 am - 7:50 amSAF-SCL
17h 10m1 stop
American Airlines Logo
11:15 pm - 11:07 amSCL-SAF
15h 52m1 stop
$979American Airlines
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Sat, Dec 6 - Wed, Dec 10
American Airlines Logo
6:15 am - 9:05 amSAF-SCL
22h 50m2 stops
American Airlines Logo
11:15 pm - 12:46 pmSCL-SAF
17h 31m1 stop
$984American Airlines
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Sat, Oct 4 - Tue, Oct 7
American Airlines Logo
10:03 am - 4:10 amSAF-LIM
17h 07m2 stops
American Airlines Logo
10:00 pm - 2:56 pmLIM-SAF
17h 56m2 stops
$1,020American Airlines
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Booking Insights

KAYAK's insights & trends for Santa Fe to South America flights

Get data-powered insights and trends into flights from Santa Fe to South America to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Santa Fe to South America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Santa Fe to South America were found on United Airlines ($844) and American Airlines ($879).

Good to know

Cheapest flight$543
Flight from Santa Fe to Santiago

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Santa Fe to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Santa Fe to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Santa Fe to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Santa Fe to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Santa Fe to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Santa Fe to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Santa Fe to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Santa Fe to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to South America?

    The cheapest time of day to fly to South America is generally in the morning, when round-trip flights cost $1,092 on average. The most expensive time of day to fly to South America is generally in the morning, which is peak travel time and where the average cost of a ticket is $1,092.

Reviews of the top airline flying from Santa Fe to South America

 
Need help choosing which airline to fly with from Santa Fe to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 10000 reviews
6.5Food
7.2Comfort
7.5Boarding
6.9Entertainment
8.0Crew
Airline reviews

The flight was canceled 3 hours after original take off time

2.0 MediocreAnonymous, Aug 2025PHL - LHR
Read more American Airlines reviews

The flight was canceled 3 hours after original take off time

My flight was delayed for several hours. Sitting at gate 16 for several hours, I got a text from Kayak the gate changed to 9 before it was announced. Very bad communication at each gate from American Airlines employees. I received 10 notifications of delay from Kayak. My vacation started off horrible! I will write to American Airlines corporate office also.

The AA staff person who checked our bags was curt and almost rude. The FA also seemed unhappy doing her job. Overall it was like riding the school bus back in grade school.

Internet was a bit expensive and did not work ask that week otherwise a good flight

Ring in first class for an overnight flight, there was no blankets nor pillows for first class customers.

My Internet did not work for Outlook email or basically anything. I paid for one hour of in-flight usage and it was terrible. I spent a lot of time on different sites and browsers with no luck and a lot of frustration. Other than that, the flight was on time, crew was nice, service was fine. Seat was OK even though I paid for the extra 6 inches. I cannot imagine how tight the seats in the back must be.

Delayed flight that lead to a missed connection and a 5-hour trip became a 12-hour flight 🙄

Any flight to ORD after about 2pm this summer has been challenging. Flight was delayed getting in (coming from ORD) and that led to it not leaving before a ground stop due to lightening before they could fuel the plane, and so forth. They made up some time but we were still late in arriving at ORD, and that led to missed connections.

Food was ok, but not as good as I have had before on AA.

No issues. They did change our gate FOUR times in about 30 minutes which was mildly annoying but the flight was fine.

Everything you need to know for your flight to South America

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