$687 Find Cheap Flights from Santa Fe to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santa Fe to South America departing on 12/18. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Santa Fe to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima2 stops$757
Santiago
Santiago2 stops$769
Lima
Lima2 stops$757
Santiago
Santiago2 stops$769

Book Cheap Santa Fe to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santa Fe to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santa Fe to South America

Sun, Mar 8 - Thu, Mar 19
American Airlines Logo
6:15 am - 4:10 am
SAF
-
LIM
20h 55m2 stops
American Airlines Logo
9:55 pm - 2:00 pm
LIM
-
SAF
17h 05m2 stops
$757American Airlines
Thu, Jan 22 - Mon, Jan 26
United Airlines Logo
7:00 am - 8:50 am
SAF
-
SCL
21h 50m2 stops
United Airlines Logo
10:45 pm - 8:47 pm
SCL
-
SAF
26h 02m2 stops
$769United Airlines
Sat, Jan 31 - Sat, Feb 14
American Airlines Logo
12:59 pm - 8:15 am
SAF
-
SCL
15h 16m1 stop
American Airlines Logo
11:15 pm - 9:39 am
SCL
-
SAF
14h 24m1 stop
$840American Airlines
Sat, Jan 31 - Sat, Feb 14
American Airlines Logo
12:59 pm - 9:00 am
SAF
-
SCL
16h 01m2 stops
American Airlines Logo
11:15 pm - 9:39 am
SCL
-
SAF
14h 24m1 stop
$844American Airlines
Sat, Jan 31 - Sat, Feb 14
American Airlines Logo
6:25 am - 9:00 am
SAF
-
SCL
22h 35m2 stops
American Airlines Logo
11:15 pm - 6:01 pm
SCL
-
SAF
22h 46m2 stops
$849American Airlines
Sat, Jan 31 - Sat, Feb 14
American Airlines Logo
6:25 am - 9:00 am
SAF
-
SCL
22h 35m2 stops
American Airlines Logo
11:55 pm - 3:02 pm
SCL
-
SAF
19h 07m2 stops
$867American Airlines
Sat, Jan 31 - Sat, Feb 14
American Airlines Logo
6:25 am - 8:15 am
SAF
-
SCL
21h 50m1 stop
American Airlines Logo
11:15 pm - 9:39 am
SCL
-
SAF
14h 24m1 stop
$890American Airlines
Tue, Feb 3 - Fri, Mar 6
United Airlines Logo
10:45 am - 8:50 am
SAF
-
SCL
18h 05m2 stops
United Airlines Logo
10:45 pm - 8:33 am
SCL
-
SAF
37h 48m2 stops
$4,570United Airlines
Tue, Feb 3 - Fri, Mar 6
American Airlines Logo
6:25 am - 8:15 am
SAF
-
SCL
21h 50m1 stop
American Airlines Logo
11:15 pm - 9:46 am
SCL
-
SAF
14h 31m1 stop
$5,910American Airlines
Tue, Feb 3 - Fri, Mar 6
American Airlines Logo
12:59 pm - 8:15 am
SAF
-
SCL
15h 16m1 stop
American Airlines Logo
10:25 pm - 8:49 pm
SCL
-
SAF
26h 24m2 stops
$5,914American Airlines
Booking Insights

KAYAK's insights & trends for Santa Fe to South America flights

Get data-powered insights and trends into flights from Santa Fe to South America to help you find the cheapest flights, the best time to fly and much more.

Which airlines fly non-stop between Santa Fe and South America?

Airline and price data is aggregated from results in KAYAK’s search results from the last 2 weeks for round-trip flights from Santa Fe to South America.

There is just one airline that flies from Santa Fe to South America direct and that is American Airlines. The best round-trip deal found from American Airlines for the route is to Lima (LIM) and costs $647.

Which airlines provide the cheapest flights from Santa Fe to South America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Santa Fe to South America were found on American Airlines ($757) and United Airlines ($769).

Good to know

Cheapest flight$687
Flight from Santa Fe to Santiago

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Santa Fe to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Santa Fe to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Santa Fe to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Santa Fe to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Santa Fe to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Santa Fe to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Santa Fe to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Santa Fe to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to South America?

    The cheapest time of day to fly to South America is generally in the morning, when round-trip flights cost $1,092 on average. The most expensive time of day to fly to South America is generally in the morning, which is peak travel time and where the average cost of a ticket is $1,092.

Reviews of the top airline flying from Santa Fe to South America

 
Need help choosing which airline to fly with from Santa Fe to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 11046 reviews
7.5Boarding
6.9Entertainment
6.5Food
8.0Crew
7.2Comfort
Airline reviews

Waaay too small plane. They also need to up the size of the overhead bins. I would love to keep me 3k with of camera equipment in my hard case baggahe instead of it being thrown into the belly of the plane

2.0 MediocreJeremy, Dec 2025
CLT - GNV
Read more American Airlines reviews

Waaay too small plane. They also need to up the size of the overhead bins. I would love to keep me 3k with of camera equipment in my hard case baggahe instead of it being thrown into the belly of the plane

Attendants were pleasant and the flight was smooth and relaxed.

A little late at the start but all worked out well.

It was fine. No drinks nor snacks offered though. I thought that was unusual.

I liked the humor of the captain and crew on the flight from Flagstaff to Dallas. They were humorous.

AA delayed the flight for 3 hours and 50 minutes, but delayed the last 2 hours, 30 minutes at a time, so if we knew before, could have stayed at home and worked instead of being at the airport wasting time... The plane's crew was excellent, not their fault.

After arriving in Dallas, the aircraft taxied for an unusually long time and was unable to park at the gate, which caused a significant delay and made me miss my connecting flight. I then had to wait in a very long line to be rebooked, and I was told that no hotel or meal accommodations would be provided. What is even more unacceptable is that my luggage was mishandled and has still not been located. My suitcase contains important medications that I urgently need, and I have been unable to access them due to the airline’s mishandling. This situation has caused me considerable stress and inconvenience, and I need this issue to be resolved immediately.

RIC Staff was not enough. Elderly passengers had to wait 30 minutes to deplane, so we could board and still had to walk as no chairs were provided. And, passenger in front of my seat assignment rammed seat against my legs entire flight time. Was mildly bruised and left thigh still sore.

Liked that it was on time. Staff professional and friendly.

Things were delayed a little. But that didn’t affect my plans. It was fine. I was surprised it was so full thanksgiving day. The crew were friendly and professional.

Everything you need to know for your flight to South America

Information on your arrival and departure airports