$353 Find Cheap Flights from Santiago to North Carolina - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santiago to North Carolina departing on 9/2. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Santiago to North Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Raleigh
Raleigh1 stop$727
Charlotte
Charlotte2 stops$802
Norfolk
Norfolk2 stops$974
Raleigh
Raleigh1 stop$727
Charlotte
Charlotte2 stops$802
Norfolk
Norfolk2 stops$974

Book Cheap Santiago to North Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santiago to North Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santiago to North Carolina

Fri, Oct 9 - Mon, Oct 19
Multiple Airlines Logo
11:55 pm - 12:17 pm
SCL
-
RDU
13h 22m
1 stop
Multiple Airlines Logo
7:05 am - 3:56 am
RDU
-
SCL
19h 51m
2 stops
$727Multiple Airlines
Sun, Aug 23 - Mon, Aug 31
Multiple Airlines Logo
11:00 pm - 5:52 pm
SCL
-
RDU
18h 52m
1 stop
Multiple Airlines Logo
9:59 pm - 2:56 am
RDU
-
SCL
28h 57m
2 stops
$729Multiple Airlines
Fri, Oct 9 - Sun, Oct 18
Multiple Airlines Logo
11:55 pm - 12:17 pm
SCL
-
RDU
13h 22m
1 stop
Multiple Airlines Logo
9:59 pm - 3:56 am
RDU
-
SCL
28h 57m
2 stops
$730Multiple Airlines
Fri, Oct 9 - Sun, Oct 18
Multiple Airlines Logo
11:55 pm - 12:17 pm
SCL
-
RDU
13h 22m
1 stop
Multiple Airlines Logo
9:59 pm - 3:56 am
RDU
-
SCL
28h 57m
2 stops
$731Multiple Airlines
Fri, Oct 9 - Mon, Oct 19
Multiple Airlines Logo
11:55 pm - 12:17 pm
SCL
-
RDU
13h 22m
1 stop
Multiple Airlines Logo
7:05 am - 3:56 am
RDU
-
SCL
19h 51m
2 stops
$732Multiple Airlines
Thu, Aug 20 - Mon, Aug 31
Delta Logo
6:45 pm - 11:11 am
SCL
-
TYS
16h 26m
2 stops
Delta Logo
4:38 pm - 6:55 am
TYS
-
SCL
14h 17m
2 stops
$916Delta
Thu, Aug 6 - Thu, Dec 10
Delta Logo
7:50 am - 11:52 pm
SCL
-
TYS
16h 02m
2 stops
Delta Logo
7:20 pm - 2:05 pm
TYS
-
SCL
16h 45m
2 stops
$925Delta
Thu, Jul 30 - Fri, Apr 30
American Airlines Logo
9:00 pm - 11:59 pm
SCL
-
TYS
26h 59m
1 stop
American Airlines Logo
8:00 am - 7:05 am
TYS
-
SCL
23h 05m
2 stops
$929American Airlines
Thu, Aug 27 - Mon, Aug 31
LATAM Airlines Logo
8:40 pm - 6:52 pm
SCL
-
TYS
22h 12m
1 stop
LATAM Airlines Logo
4:38 pm - 7:15 am
TYS
-
SCL
14h 37m
1 stop
$935LATAM Airlines
Wed, Sep 2 - Wed, Sep 9
LATAM Airlines Logo
7:50 am - 11:52 pm
SCL
-
TYS
16h 02m
2 stops
LATAM Airlines Logo
1:31 pm - 2:25 pm
TYS
-
SCL
23h 54m
3 stops
$940LATAM Airlines
Booking Insights

KAYAK's insights & trends for Santiago to North Carolina flights

Get data-powered insights and trends into flights from Santiago to North Carolina to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Santiago to North Carolina?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Santiago to North Carolina departing in August.

What is the cheapest month to fly from Santiago to North Carolina?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Santiago to North Carolina, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Santiago to North Carolina is November, when tickets cost $752 (return) on average. On the other hand, the most expensive months are February and September, when the average cost of round-trip tickets is $1,185 and $1,173 respectively.

How far in advance should I book a flight from Santiago to North Carolina?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Santiago to North Carolina, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Santiago to North Carolina, you should book around 5 weeks before departure, which saves you about 33% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 11 weeks before departure.

Good to know

Low season

September

Cheapest flight

$353
Best time to beat the crowds but there is an average 23% increase in price.
Most popular time to fly and prices are also 14% lower on average.
Flight from Santiago to Raleigh

FAQs - booking North Carolina flights

  • How does KAYAK find such low prices on flights from Santiago to North Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Santiago to North Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Santiago to North Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Santiago to North Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Santiago to North Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Santiago to North Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Santiago to North Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Santiago to North Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 4 airlines serving from Santiago to North Carolina

 
See real verified KAYAK customer reviews for airlines flying from Santiago to North Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santiago to North Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
DeltaOverall score based on 8479 reviews
8.1Boarding
7.8Entertainment
7.8Comfort
8.5Crew
7.2Food
Airline reviews

I thought the service was very nice and pleasant. There were no hiccups and no issues so overall a good experience.

8.0 ExcellentAnonymous, Jun 2026
BOS - RDU
Read more Delta reviews

I thought the service was very nice and pleasant. There were no hiccups and no issues so overall a good experience.

Average seat comfort, a drink and chips were provided, early boarding because we checked a carryon at the gate was nice. Ticket pricing shenanigans, including fees to pick a seat, check a bag, and get food onboard - evidence the industry is reinvigorating last century’s strategies- destroys the experience before one ever arrives at the airport. It’s difficult to recognize any value or sustain loyalty in the end-to-end process making air travel more drudgery than pleasure.

WiFi didn’t work. Flight delayed 3 hours Crew members were illiterate Seat lean back did not work.

The plan was delayed and left DC 90 minutes late. However, it showed a 20 minute delay on the delta app, then a 12 min delay. It turned out to be an hour delay. I found out where the plane was with flightaware. Stop keeping customers in the dark about what is going on.

Could not get my connecting flight boarding pass until four hrs before departure! Ver annoying especially since the staff could not explain why!

Smooth boarding, pleasant and professional lady checking us in. Crew service was excellent, again pleasant, but professional. Nice touch-down on landing! Thank you Delta. 💗

I've flown several other airlines, and Delta is really on top on things.

The crew was very nice and very attentive. However, I was surprised to find that they did not carry small throw-up bags. I got sick from the turbulence and they had to bring me a trash bag.😳 You can imagine how embarrassing is to lift a large trash bag with vomit over somebody else's head. Just bring this small discreet little bags back to the regular supply for the seats. Otherwise, I love Delta airlines.

Worst food I've ever seen on a plane. One flight attendant must have been going through a bad breakup, although the one who kept covering for her was excellent.

The crew in Chile was late to open the counter to check in. It was the longest check in ever. But they were pleasant and thorough. Food was great going to Chile, coming back to USA was pretty bad. All the airplane crew were great.

stood in line to check in luggage for nearly an hour. very poor service and not excusable

Same as the previous flight as far as comfort and food. Entertainment didn’t have a watchable screen so everything would need to be watched on your own device in which they didn’t have a charging port that accommodated my iPhone. Seats were very uncomfortable. Staff was very friendly.

They didn’t have any headphones for the entertainment screen and their USB port didn’t accommodate a USB-C for more modern phones. The food was just ok. The staff was friendly but the seats were very uncomfortable for a full flight.

Do not book it’s a scam! They stole $1200 from me

Flight got delayed; had to go through security three times.

A lot things happened in this trip.The fly should be less stress.

Some of the Air hostesses are not that friendly. Need improvement

We had a great flight just wished they had a tv so we can see a movie that would of made my trip excellent.

Copa delayed the fight three times. We ended up flying about 24 hours after the original time.

Food was not good, no options for vegetarian or gluten free

In flight from Miami to Anchorage, we were all on board ready to take off. Pilot decided to take on more fuel causing a delay. Once fueled, the pilot came back over the radio stating more delay due to VIP. These delays caused me to miss my connecting flight. I went to the Alaska Air counter for information. They flat out stated that it was ATCs fault that I missed my flight and booked me a flight the next day about 1300 . I believe if we had the fuel prior to getting on board we would not of been delayed and I would have taken off on time. Pilot was taken out of the equation. I think they should’ve taken responsibility for their pilots decision to top off his aircraft instead of waiting til the last moment. Enough said…

We liked the way we were treated by the sraff at lima airport counter and the the flight attendants. We did not like the fact that the kiosks at airport rebooted after we entered our information and then told us that there was an issueand we needed to go to the counter. Such a waste of time for a group of 6. Once we got our boarding passes there was no assigned gate so we did not know where to go.

The plane broke down at the Lima stopover and they offered to put me on a flight the be t day but I had to be back in LA that morning and so I had to buy another ticket from Avianca and United for $2k I asked LATAM for compensation and received none. Very bad experience

Change of gate in Santiago devolved into half plus hour delay and a really tight connection in Lima

They didi not provide wheelchair though we had requested. We had to run around for 40 minutes and arrange it from the airport!

Everything was good except the check in. Could not do it online neither on the machines in the airport. Needed special assistance from the airline desk clerk

Great customer service, very accommodating. (Check in) Smooth flight, thank you Pilots. Only negative was one working bathroom in first class. Atlanta Base flight attendants were wonderful. Thank you for your smiling faces Delta..

The seats are getting smaller and smaller. Very uncomfortable trip. More than in other airlines

I do not speak Spanish or read in Spanish When asking for help, people were hard to find they spoke quickly and pointed a lot directions for where to go and what to do we’re unclear. Which made my traveling uneasy.

Flight was great Customer service was questionable until we found someone at checkin to help us. One young lady took all our passports disappeared for 15 minutes, came back with nothing done, handed to someone else and left for lunch. Very complacent. Baggage was very expensive until we went to the service counter and a separate person helped us. Even with platinum status they wouldn’t allow free bags. We will continue to fly Delta as our preferred carrier but will avoid checking in with Latam. Dr. Armand Radke

As I said I never took the flight back from due to earlier delayed that prevented from taking the second trip back and nobody helped me to rebook from kayak

Upgraded to first class. I would consider the first class on that plane to be only slightly more comfortable than coach. Long delay.

It’s love good long way travel!! I always want more give me price down i want ever month travel I miss travel only North Carolina to Thailand in my love her !!

Efficiency of supporting mechanical teams who changed a wheel on airplane in minutes. So no delay, and pilot made up the lost minutes in flight. Comfortable seat.

Extremely comfortable airplane, everything looked brand new, how lovely! My seat in Premium Economy was ever so comfortable, I did not suffer the usual backache I suffer when doing the transatlantic flight. It felt like seating in a reclining armchair. I loved the foot rest, did not need to use the portable device I usually carry along with me to replace one. I loved the spaciousness in front of me, and that there were only two seats (Instead of 3 in coach) in the window row, wow what a difference in comfort. Coach seats are always just a little narrow for my hips. The support of the cushions was great, firm and offered good support . It was easy to come out of my aisle seat, although I'm 70. The staff was courteous, both meals were delicious, very carefully prepared, and creative (fruit + cheese for the second meal, instead of the usual bread sandwich)

3 hour delay before takeoff & another 30 minutes on the plane before taxi to runway

My entertainment unit kept locking up and had to be restarted multiple times. Also those commercials for Budapest and Ralph Laureen. Come on those were stuff only those who can afford the outrageous fees of first and business class would be interested in.. And the fact you have no military discount is not good either,

I was not clear if food was offered or not.

They did not offer coffee on a 7am flight…awful!!

The person next to me used my leg space up and made it an uncomfortable ride the whole time

Everything you need to know for your flight from Santiago to North Carolina

Information on your arrival and departure airports