$109 Find Cheap Flights from Buffalo to South Carolina - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Buffalo to South Carolina departing on 8/4. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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Cheap Flights from Buffalo to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Charleston
Charleston1 stop$239
Myrtle Beach
Myrtle Beach2 stops$284
Greenville
Greenville2 stops$280
Columbia
Columbia1 stop$261
Florence
Florence1 stop$501
Charlotte
Charlotte1 stop$210
Charleston
Charleston1 stop$239
Myrtle Beach
Myrtle Beach2 stops$284
Greenville
Greenville2 stops$280
Columbia
Columbia1 stop$261
Florence
Florence1 stop$501
Charlotte
Charlotte1 stop$210

Book Cheap Buffalo to South Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Buffalo to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Buffalo to South Carolina

Wed, Aug 5 - Wed, Aug 12
Frontier Logo
7:57 pm - 7:51 am
BUF
-
CLT
11h 54m
1 stop
Frontier Logo
12:24 pm - 7:06 pm
CLT
-
BUF
6h 42m
1 stop
$210Frontier
Wed, Aug 12 - Wed, Aug 19
Frontier Logo
7:57 pm - 7:51 am
BUF
-
CLT
11h 54m
1 stop
Frontier Logo
9:52 pm - 9:23 am
CLT
-
BUF
11h 31m
1 stop
$211Frontier
Tue, Aug 18 - Tue, Aug 18
United Airlines Logo
6:55 am - 1:58 pm
BUF
-
CHS
7h 03m
1 stop
United Airlines Logo
7:51 pm - 11:44 pm
CHS
-
BUF
3h 53m
1 stop
$239United Airlines
Tue, Aug 18 - Tue, Aug 25
Southwest Logo
6:00 am - 12:35 pm
BUF
-
CHS
6h 35m
1 stop
Southwest Logo
7:35 am - 2:20 pm
CHS
-
BUF
6h 45m
2 stops
$244Southwest
Tue, Aug 11 - Tue, Aug 18
Delta Logo
7:19 pm - 11:59 pm
BUF
-
CHS
4h 40m
1 stop
Delta Logo
2:17 pm - 6:55 pm
CHS
-
BUF
4h 38m
1 stop
$251Delta
Tue, Aug 18 - Wed, Aug 19
United Airlines Logo
6:55 am - 1:58 pm
BUF
-
CHS
7h 03m
1 stop
United Airlines Logo
7:51 pm - 11:44 pm
CHS
-
BUF
3h 53m
1 stop
$253United Airlines
Tue, Aug 18 - Tue, Aug 25
Southwest Logo
6:00 am - 12:35 pm
BUF
-
CHS
6h 35m
1 stop
Southwest Logo
7:35 am - 2:20 pm
CHS
-
BUF
6h 45m
2 stops
$256Southwest
Sat, Aug 15 - Sat, Aug 22
American Airlines Logo
5:32 am - 9:45 am
BUF
-
CAE
4h 13m
1 stop
American Airlines Logo
5:51 pm - 9:55 pm
CAE
-
BUF
4h 04m
1 stop
$261American Airlines
Tue, Aug 11 - Sat, Aug 15
American Airlines Logo
6:00 am - 12:06 pm
BUF
-
CAE
6h 06m
1 stop
American Airlines Logo
6:36 pm - 11:56 pm
CAE
-
BUF
5h 20m
1 stop
$285American Airlines
Wed, Nov 11 - Wed, Nov 18
Delta Logo
4:59 pm - 11:59 pm
BUF
-
SAV
7h 00m
1 stop
Delta Logo
11:00 am - 3:11 pm
SAV
-
BUF
4h 11m
1 stop
$291Delta
Booking Insights

KAYAK's insights & trends for Buffalo to South Carolina flights

Get data-powered insights and trends into flights from Buffalo to South Carolina to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Buffalo to South Carolina?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Buffalo to South Carolina departing in August.

What is the cheapest month to fly from Buffalo to South Carolina?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Buffalo to South Carolina, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Buffalo to South Carolina is September, when tickets cost $277 (return) on average. On the other hand, the most expensive months are March and April, when the average cost of round-trip tickets is $433 and $408 respectively.

How far in advance should I book a flight from Buffalo to South Carolina?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Buffalo to South Carolina, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Buffalo to South Carolina, you should book around 3 weeks before departure, which saves you about 42% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 24 weeks before departure.

Good to know

Low season

January

Cheapest flight

$109
Best time to beat the crowds with an average 18% drop in price.
Most popular time to fly with an average 17% increase in price.
Flight from Buffalo to Charlotte

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Buffalo to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Buffalo to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Buffalo to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Buffalo to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Buffalo to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Buffalo to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Buffalo to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Buffalo to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Top tips for finding cheap flights to South Carolina

  • Looking for a cheap flight? 25% of our users found tickets from Buffalo to the following destinations at these prices or less: Charlotte $196 one-way - $341 round-trip

Reviews of the top 5 airlines serving from Buffalo to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Buffalo to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Buffalo to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4241 reviews
7.5Entertainment
8.6Crew
8.0Comfort
8.1Boarding
7.0Food
Airline reviews

Flight coming out of Buffalo was delayed, so we had to be rescheduled on another flight from Baltimore to Phoenix which means we had a long layover and got home 3.5 hours late. Shuttle to parking stopped at 10pm, so we had to pay for an Uber to the parking lot and got charged an extra day of parking since it was after midnight. Not the best experience. Long day!

2.0 MediocreDawn, Jun 2026
BUF - BWI
Read more Southwest reviews

Flight coming out of Buffalo was delayed, so we had to be rescheduled on another flight from Baltimore to Phoenix which means we had a long layover and got home 3.5 hours late. Shuttle to parking stopped at 10pm, so we had to pay for an Uber to the parking lot and got charged an extra day of parking since it was after midnight. Not the best experience. Long day!

I'm glad it wasn't only 75% full because I could get a good seat

We had a 5 hour delay on the tarmac in Baltimore

Check-in, Boarding and flight were smooth. All the employees and crew was very nice and funny. They gave the kids crayons and workbooks to keep them occupied which was a big win. I’ve flown Southwest many times and that’s the first time I’ve seen that and it is a great addition.

Airline travel is always too cramped to really be pleasant, but the cabin crew on this flight did a pretty good job of making up for it by putting on some music during boarding and sprinkling a few funny remarks into the safety briefing and announcements, and just generally being friendly and helpful. It definitely reminded me of why I prefer the in-flight experience on Southwest!

Flight was delayed due to plane not passing inspection And one of the crew had to time out and we had to wait for another one A 3 hour delay

It went well. Plane wasn't full. Will be great when assigned seating is in place

As always it was a pleasure to fly on southwest.

Excellent! There was a delay due to the weather and they did all they could do to keep us comfortable & updated. Thank you!

Couldn't connect to the internet and movies. Needed help.

Flight delayed due to ground hold. Republic airways did a great job.

Flight was delayed before take off and at landing. Baggage took 20 minutes. Flight crew would not serve full soft drink and had to ask multiple times before receiving water.

For some reason, TSA Atlanta didn’t have my bag on the flight on time and they don’t have to provide Delta a reason for that.

I am still at the Airport! Delayed Delayed and Delyaed

The landing was the worst I’ve experienced with a flight.

It was last minute due to weather - considering - it was amazing! Good smiles, friendly staff and they were making sure we knew what was going on when and where.

All good on Delta's part. Passengers could be a little more courteous to each other.

The pilots were good. Disappointing when planes don't have electrical ports

No complaints - left 20 minutes later than planned but still arrived on time.

Crew handling the boarding at the gates are quite aggressive with the passengers and must be given training/ refreshing courses to improve customer experience.

The seats on this flight weren’t as comfortable as we had expected. Even leaned back these seats left us feeling crappy in our backs. Also we had to use our own tablets for movies, but nothing in the seats in front of us to hold the tablets up.

Awful. No counter attendants. No dinner offered due to delays.

3 hour delay…. Nearly 2 hours sitting on tarmac. Do better, United. Or at least have the sense to not say “we hope you enjoyed your flight with us” upon disembarking.

Everything except the food and entertainment. It was a great experience though

Unfortunately weather delayed our flight waiting for our plane to arrive and due to a little snow time was needed to deice the plane so departure was very delayed and I missed the connecting flight

The flight attendants were unhelpful. It was a packed flight, and usually a flight attendant would help find a spot in the bin for your carry on or shift things around. Neither made any effort to do so. Also, I had to then check my bag. I was told it would be on the carousel in YYZ, but it came up on the jetway. So lucky I saw others standing around for their bags. I would have walked straight past this and on to the carousel. They could have at least told me that they had given me wrong information. Very unsatisfactory.

The staff was very friendly. The seats seemed quite small. Overall the flight was pleasant.

Delays!!! Serious delays. I was told by a member of staff in LGA that I would miss my DEN to LAX flight connection, so I was put on a later flight. Due to delays I would have been able to have made my original flight, where I was sat in business class - seat 1A: I was put on my original flight but bumped from business - 1A to economy 33C. I want a refund for paying business class but only flying economy

The plane was delayed coming in and on the tarmac. I was coming from another flight so it made for a very long day. The stewardess kept trying to slam the overhead bins closed and I was worried that she had damaged my new luggage. They ran out of snacks and lccdsddd me a hummus box which was nice. It took them a very long time to pick up the garbage so I could not go to the washroom and had little time. To prepare for disbarment. The TV system was hard to control from the armrest and picture wasn’t clear. The crew did apologize several times for the lateness. It took the Denver airport an unusually long time to de-ice the plane.

Their app did not recognize my Aeroplan frequent flyer number and would not allow me access to my boarding card. Ground staff was readily available at the airport to print it out to me.

Crew and agents misguiding on tight connections, and lack of connecting crew looking for inbound planes. A very avoidable missed connection as a result.

I don’t like the music section but I believe it was a cost decision. I changed my flight last minute due to work issues and had to sit way in the back. The seats were way closer together than I would have preferred.

The flight attendant was very polite and attentive. The food was good.

Very turbulent flight, no drinks, very little service, unorganized boarding, gate changed multiple times

Poor seat in rear of aircraft Food at Admiral’s Club Terminal D at DFW inedible

The flight from Buffalo to Chicago was on an older and smaller plane. Seating was tight. Looking closely at the interior of the aircraft there were definitely signs of aging and wear.

Multiple gate changes and significant delay leaving DFW. Made for a late arrival

For the price of the ticket you get nothing. The plane had 1 bathroom in the back and when the flight attendant did service no one could use it. No announcement just was told to go back to my seat. Ridiculous and rude.

In-flight Wi-Fi didn’t work and the flight was 25 minutes late. The Embraer plane I was on was pretty old and the tray table was broken.

American Airlines no longer has Bischoff biscuits. This is intolerable.

The flight was delayed. I upgraded to more room. I can't imagine how small the regular seats are I haven't upgraded for my return flight yet.

Flight was cancelled, no support at JFK even though it is their main hub.. wait times on the phone was very long

When I agreed to give up my two seats because of overbooking by the airline, I should have been offered some sort of reward or credit towards a future flight. I was not. It was not until the next day when I mentioned it to a Jet Blue employee that I was advised to call 1-800-JetBlue. So here I am, having done Jet Blue a favor and I had to do the work to find out if I was going to get a credit. Such service

Domestic flights are good. Just stay away from international travel

Since we started at syr the service, crews, and flights were just excellent

Boarding process was terrible. No assigned seat until the gate, then a long line to get seat assignment.

JetBlue was good. Kayak offered us a deal if we bundled the rental car. This was a complete scam. Kayak said the total was $222... but when we went to pick up the car the agent at Rent a wreck said that we had to pay "fees and taxes" for a grand total of $750. I would recommend not using kayak or rent a wreck. They are both complicit in this scam. JetBlue worked out well.

TV was broken and could not shut it off. The flicking was bother me and gave me a headache. The WiFi wouldn’t work correctly, I was able to text but not search the web or surf social media. The plane itself had a lot of wear and tear it is due for an update.

Excellent price. Everything on time. two bad parts. Kayak said I couldn't sign in for the flight online, but I got an email at the same time from Jet Blue and they let me sign in online. Second bad part was that, although I had provided my known traveler number, neither of my boarding passes, for this flight and the previous one, had TSA pre-check showing.

In-flight staff was very helpful and excellent. However, the flight was delayed by 90 minutes. Also the boarding process should be expedited in case of delayed flights. This will help the passengers trying to make international connections.

Everything you need to know for your flight from Buffalo to South Carolina

Information on your arrival and departure airports