CLO - GYE

$272 Find Cheap Flights from Cali to Guayaquil - Compare and Save

1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$340
Typical prices: $320-$415
Avianca
Wed 10/17Fri 10/19
CLO - GYE • 2 stops
Cheapest one-way
$272
Typical prices: $175-$236
Copa Airlines
Fri 10/19
CLO - GYE • 1 stop
Nonstop flights
Not available
There are currently no direct flights between Cali and Guayaquil. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to book
13 weeks
in advance
Our data shows that travelers who book at least 13 weeks in advance save around 16% compared to booking last minute.
Insights
Insights
When to travel
February
Cheapest • 22% price drop
December
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Bogotá El Dorado (BOG)
Cheapest • Avg $374 (round-trip)
Panama City Tocumen Intl (PTY)
Shortest trip • 5h 32m (one-way)
Insights
Insights
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We hope you love your trip to Guayaquil!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Cali to Guayaquil (CLO-GYE)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Cali to Guayaquil

Sat, Oct 17 - Mon, Oct 19
Avianca Logo
10:10 am - 10:15 amCLO  Cali Alfonso B. Aragon Intl-GYE Guayaquil Jose Joaquin de Olmedo
24h 05m2 stops Medellín Jose Maria Cordova Intl Quito Mariscal Sucr
Avianca Logo
10:05 am - 9:05 pmGYE  Guayaquil Jose Joaquin de Olmedo-CLO Cali Alfonso B. Aragon Intl
11h 00m1 stop Bogotá El Dorado
$340Avianca
Sat, Oct 17 - Mon, Oct 19
LATAM Airlines Logo
9:50 pm - 4:28 pmCLO  Cali Alfonso B. Aragon Intl-GYE Guayaquil Jose Joaquin de Olmedo
18h 38m2 stops Bogotá El Dorado Quito Mariscal Sucr
LATAM Airlines Logo
7:23 pm - 12:55 pmGYE  Guayaquil Jose Joaquin de Olmedo-CLO Cali Alfonso B. Aragon Intl
17h 32m2 stops Quito Mariscal Sucr Bogotá El Dorado
$377LATAM Airlines
Fri, Oct 9 - Tue, Oct 13
LATAM Airlines Logo
5:25 am - 7:37 pmCLO  Cali Alfonso B. Aragon Intl-GYE Guayaquil Jose Joaquin de Olmedo
14h 12m2 stops Bogotá El Dorado Quito Mariscal Sucr
LATAM Airlines Logo
8:25 am - 12:45 amGYE  Guayaquil Jose Joaquin de Olmedo-CLO Cali Alfonso B. Aragon Intl
16h 20m2 stops Quito Mariscal Sucr Bogotá El Dorado
$389LATAM Airlines
Tue, Oct 13 - Fri, Oct 23
Copa Airlines Logo
3:10 pm - 1:33 pmCLO  Cali Alfonso B. Aragon Intl-GYE Guayaquil Jose Joaquin de Olmedo
22h 23m1 stop Panama City Tocumen Intl
Copa Airlines Logo
8:24 am - 2:10 pmGYE  Guayaquil Jose Joaquin de Olmedo-CLO Cali Alfonso B. Aragon Intl
5h 46m1 stop Panama City Tocumen Intl
$410Copa Airlines
Sun, Oct 11 - Sat, Oct 17
Copa Airlines Logo
6:25 pm - 1:33 pmCLO  Cali Alfonso B. Aragon Intl-GYE Guayaquil Jose Joaquin de Olmedo
19h 08m1 stop Panama City Tocumen Intl
Copa Airlines Logo
6:30 pm - 5:21 pmGYE  Guayaquil Jose Joaquin de Olmedo-CLO Cali Alfonso B. Aragon Intl
22h 51m1 stop Panama City Tocumen Intl
$410Copa Airlines
Mon, Oct 19 - Sun, Oct 25
Copa Airlines Logo
6:25 pm - 1:33 pmCLO  Cali Alfonso B. Aragon Intl-GYE Guayaquil Jose Joaquin de Olmedo
19h 08m1 stop Panama City Tocumen Intl
Copa Airlines Logo
6:40 pm - 11:02 amGYE  Guayaquil Jose Joaquin de Olmedo-CLO Cali Alfonso B. Aragon Intl
16h 22m1 stop Panama City Tocumen Intl
$410Copa Airlines
Mon, Nov 30 - Sun, Jan 24
Copa Airlines Logo
6:14 pm - 11:22 amCLO  Cali Alfonso B. Aragon Intl-GYE Guayaquil Jose Joaquin de Olmedo
17h 08m1 stop Panama City Tocumen Intl
Copa Airlines Logo
2:44 pm - 11:00 amGYE  Guayaquil Jose Joaquin de Olmedo-CLO Cali Alfonso B. Aragon Intl
20h 16m1 stop Panama City Tocumen Intl
$410Copa Airlines
Fri, Oct 16 - Tue, Nov 3
Copa Airlines Logo
12:06 pm - 5:30 pmCLO  Cali Alfonso B. Aragon Intl-GYE Guayaquil Jose Joaquin de Olmedo
5h 24m1 stop Panama City Tocumen Intl
Copa Airlines Logo
6:38 pm - 10:57 amGYE  Guayaquil Jose Joaquin de Olmedo-CLO Cali Alfonso B. Aragon Intl
16h 19m1 stop Panama City Tocumen Intl
$410Copa Airlines
Wed, Oct 7 - Thu, Oct 22
Copa Airlines Logo
6:25 pm - 12:01 amCLO  Cali Alfonso B. Aragon Intl-GYE Guayaquil Jose Joaquin de Olmedo
5h 36m1 stop Panama City Tocumen Intl
Copa Airlines Logo
6:30 pm - 5:52 pmGYE  Guayaquil Jose Joaquin de Olmedo-CLO Cali Alfonso B. Aragon Intl
23h 22m1 stop Panama City Tocumen Intl
$410Copa Airlines
Mon, Oct 5 - Thu, Oct 8
Avianca Logo
2:45 pm - 6:50 pmCLO  Cali Alfonso B. Aragon Intl-GYE Guayaquil Jose Joaquin de Olmedo
4h 05m1 stop Medellín Jose Maria Cordova Intl
Avianca Logo
3:30 am - 12:00 pmGYE  Guayaquil Jose Joaquin de Olmedo-CLO Cali Alfonso B. Aragon Intl
8h 30m1 stop Bogotá El Dorado
$414Avianca
Booking Insights

Price, demand and travel trends for Cali to Guayaquil flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights from Cali to Guayaquil with more confidence.

How much is a round-trip flight from Cali to Guayaquil?

Round-trip flights from Cali to Guayaquil start at $340. Prices are typical for this route right now, with typical round-trip fares ranging from $320 to $415. The lowest price found in the past 5 days was $340 on Avianca.

What's the cheapest day of the week to fly from Cali to Guayaquil?

Thursday is the cheapest day of the week to fly from Cali to Guayaquil, it is 5% cheaper than the average day. Monday is the most expensive day with flight prices 1% higher than average. Based on deals found by KAYAK users in the last 12 months.

What is the cheapest month to fly from Cali to Guayaquil?

•February is the cheapest month to fly from Cali to Guayaquil at $298 round-trip.
•April ($414) and August ($386) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 38% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

When are prices from Cali to Guayaquil the cheapest?

Flights from Cali to Guayaquil are cheapest 13 weeks before departure. Booking in this window typically costs about 16% less than the average last-minute fare (within 2 weeks of the flight), based on KAYAK data.

Find deals

Key details for Cali to Guayaquil flights

Low season

September

Cheapest flight

$272
Best time to beat the crowds with an average 4% drop in price.
Flight from Cali to Guayaquil

When to book flights from Cali to Guayaquil

Are your dates flexible? Find out the best times to travel from Cali to Guayaquil based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Cali to Guayaquil flight questions, answered

Find helpful route details based on KAYAK data, including flight times, airports, airlines and booking questions.

  • What cabin classes can I book on flights from Cali to Guayaquil?

    Only Economy Class is available on flights from Cali to Guayaquil.

  • How long is a flight from Cali to Guayaquil?

    A nonstop flight from Cali to Guayaquil takes 0h 00m, covering 462 miles.

  • Do I need a passport to fly from Cali to Guayaquil?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • How much should I expect to pay for a Cali to Guayaquil flight?

    Round-trip flights from Cali to Guayaquil range from $320 to $415, with an average of $381 over the past 12 months. Anything below $320 counts as a good deal.

  • How expensive are last-minute Cali to Guayaquil flights?

    Last-minute fares on this route - booked within 2 weeks of departure - run 3% below the route average of $381. Booking late can sometimes save money on this route, but inventory is limited.

  • Have flight prices from Cali to Guayaquil changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route varied from about $340 to $635. That means the highest observed fare was about 86% higher than the lowest one.

  • How are flight prices from Cali to Guayaquil looking right now?

    One-way fares from Cali to Guayaquil are currently higher than usual. Average one-way flight prices are about $272, which is 37% above the typical average for this route.

  • What car rental options are available at Guayaquil Jose Joaquin de Olmedo Airport (GYE)?

    Guayaquil Jose Joaquin de Olmedo Airport (GYE) hosts 5 major car rental companies, with daily rates starting from around $13 for economy cars. Top options include:
    • Europcar
    • Fox
    • Sixt
    • Alamo
    • keddy by Europcar

  • Which airports can I use when flying from Cali to Guayaquil?

    Flights from Cali to Guayaquil usually depart from Cali Alfonso B. Aragon Intl (CLO) and arrive at Guayaquil Jose Joaquin de Olmedo (GYE).

  • Which airports do connecting flights from Cali to Guayaquil pass through?

    Connecting flights from Cali to Guayaquil most commonly pass through:

    • Bogotá El Dorado (BOG) - 73% of one-stop connections
    • Panama City Tocumen Intl (PTY) - 27% of one-stop connections
    Together, these airports account for 100% of one-stop bookings on this route.

  • Can I save money by using flexible dates for flights from Cali to Guayaquil?

    Yes. Being flexible with your travel dates can save you up to 7% on the Cali to Guayaquil route. Thursday is the cheapest departure day at $362 round-trip on average, while Monday is the most expensive at $386, a difference of $24. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • How much time can I save by choosing a different layover airport from Cali to Guayaquil?

    Flying via Bogotá El Dorado (BOG) gives the shortest average 1-stop total travel time at 4h 49m, compared with 5h 32m via Panama City Tocumen Intl (PTY).

Your guide to booking Cali to Guayaquil flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates can be flexible, aim for a Thursday departure instead of Monday. On this route, Thursday flights average $362 - about $24 less than Monday (6% savings) based on the last 12 months.
  • For the best chance at a low fare, aim to book around 13 weeks before you fly. On this route, that window historically saves about 16% versus last-minute pricing (KAYAK booking data, last 12 months).
  • If you can choose when to travel, plan your Cali to Guayaquil trip for February. Fares historically average $298 round-trip in that month - typically $116 less than the most expensive month, which is April (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Guayaquil Jose Joaquin de Olmedo Airport.
    - Sheraton Guayaquil Hotel
    - Radisson Hotel Guayaquil
    - Wyndham Guayaquil Puerto Santa Ana

More options for your flight from Cali to Guayaquil

Complete your trip to Guayaquil with a hotel stay or car rental

Car rentals in Guayaquil
Hotels in Guayaquil