CLO - SDQ

$333 Find Cheap Flights from Cali to Santo Domingo - Compare and Save

1 adult
1 adult, Economy, 0 bags

Save 25% or more on flights. Compare deals from all over the web.

Never overpay with our price tracking tools.

Filter searches by price, airline and more to find your best flights.

Everything you should know

Cheapest round-trip
$423
Typical prices: $387-$471
Copa Airlines
Tue 11/20Sun 11/25
CLO - SDQ • 1 stop
Cheapest one-way
$333
Typical prices: $242-$331
Copa Airlines
Wed 11/21
CLO - SDQ • 1 stop
Nonstop flights
Not available
There are currently no direct flights between Cali and Santo Domingo. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to book
17 weeks
in advance
Our data shows that travelers who book at least 17 weeks in advance save around 17% compared to booking last minute.
Insights
Insights
When to travel
February
Cheapest • 14% price drop
December
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Medellín Jose Maria Cordova Intl (MDE)
Cheapest • Avg $414 (round-trip)
Panama City Tocumen Intl (PTY)
Shortest trip • 6h 19m (one-way)
Insights
Insights
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Santo Domingo!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Cali to Santo Domingo (CLO-SDQ)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Cali to Santo Domingo

Tue, Jan 19 - Tue, Feb 23
Copa Airlines Logo
12:03 pm - 10:54 pmCLO  Cali Alfonso B. Aragon Intl-SDQ Santo Domingo Las Americas
9h 51m1 stop Panama City Tocumen Intl
Copa Airlines Logo
12:05 pm - 5:33 pmSDQ  Santo Domingo Las Americas-CLO Cali Alfonso B. Aragon Intl
6h 28m1 stop Panama City Tocumen Intl
$423Copa Airlines
Mon, Feb 8 - Tue, Feb 23
Copa Airlines Logo
8:39 am - 4:08 pmCLO  Cali Alfonso B. Aragon Intl-SDQ Santo Domingo Las Americas
6h 29m1 stop Panama City Tocumen Intl
Copa Airlines Logo
12:05 pm - 5:33 pmSDQ  Santo Domingo Las Americas-CLO Cali Alfonso B. Aragon Intl
6h 28m1 stop Panama City Tocumen Intl
$423Copa Airlines
Fri, Feb 5 - Wed, Feb 10
Copa Airlines Logo
11:58 am - 1:06 pmCLO  Cali Alfonso B. Aragon Intl-SDQ Santo Domingo Las Americas
24h 08m1 stop Panama City Tocumen Intl
Copa Airlines Logo
12:42 pm - 11:35 pmSDQ  Santo Domingo Las Americas-CLO Cali Alfonso B. Aragon Intl
11h 53m1 stop Panama City Tocumen Intl
$423Copa Airlines
Sat, Feb 13 - Wed, Feb 24
Copa Airlines Logo
4:36 am - 11:42 amCLO  Cali Alfonso B. Aragon Intl-SDQ Santo Domingo Las Americas
6h 06m1 stop Panama City Tocumen Intl
Copa Airlines Logo
12:05 pm - 5:33 pmSDQ  Santo Domingo Las Americas-CLO Cali Alfonso B. Aragon Intl
6h 28m1 stop Panama City Tocumen Intl
$423Copa Airlines
Mon, Feb 8 - Tue, Feb 23
Avianca Logo
8:50 am - 5:50 pmCLO  Cali Alfonso B. Aragon Intl-SDQ Santo Domingo Las Americas
8h 00m1 stop Bogotá El Dorado
Avianca Logo
12:45 pm - 6:30 pmSDQ  Santo Domingo Las Americas-CLO Cali Alfonso B. Aragon Intl
6h 45m1 stop Bogotá El Dorado
$429Avianca
Mon, Feb 8 - Tue, Feb 23
Avianca Logo
8:50 am - 5:50 pmCLO  Cali Alfonso B. Aragon Intl-SDQ Santo Domingo Las Americas
8h 00m1 stop Bogotá El Dorado
Avianca Logo
12:45 pm - 6:30 pmSDQ  Santo Domingo Las Americas-CLO Cali Alfonso B. Aragon Intl
6h 45m1 stop Bogotá El Dorado
$429Avianca
Mon, Feb 8 - Tue, Feb 16
Avianca Logo
9:20 am - 5:50 pmCLO  Cali Alfonso B. Aragon Intl-SDQ Santo Domingo Las Americas
7h 30m1 stop Bogotá El Dorado
Avianca Logo
12:45 pm - 9:45 pmSDQ  Santo Domingo Las Americas-CLO Cali Alfonso B. Aragon Intl
10h 00m1 stop Bogotá El Dorado
$429Avianca
Thu, Dec 24 - Thu, Jan 7
Multiple Airlines Logo
12:16 pm - 6:42 pmCLO  Cali Alfonso B. Aragon Intl-SDQ Santo Domingo Las Americas
5h 26m1 stop Medellín Jose Maria Cordova Intl
Multiple Airlines Logo
7:32 pm - 7:38 amSDQ  Santo Domingo Las Americas-CLO Cali Alfonso B. Aragon Intl
13h 06m2 stops Medellín Jose Maria Cordova Intl Bogotá El Dorado
$453Multiple Airlines
Sat, Jan 16 - Sun, Jan 24
Multiple Airlines Logo
6:42 am - 1:37 pmCLO  Cali Alfonso B. Aragon Intl-SDQ Santo Domingo Las Americas
5h 55m1 stop Medellín Jose Maria Cordova Intl
Multiple Airlines Logo
3:58 pm - 6:19 amSDQ  Santo Domingo Las Americas-CLO Cali Alfonso B. Aragon Intl
15h 21m2 stops Medellín Jose Maria Cordova Intl Bogotá El Dorado
$459Multiple Airlines
Thu, Jan 14 - Thu, Jan 21
Multiple Airlines Logo
10:24 pm - 1:32 pmCLO  Cali Alfonso B. Aragon Intl-SDQ Santo Domingo Las Americas
14h 08m1 stop Medellín Jose Maria Cordova Intl
Multiple Airlines Logo
7:35 am - 9:09 pmSDQ  Santo Domingo Las Americas-CLO Cali Alfonso B. Aragon Intl
14h 34m1 stop Bogotá El Dorado
$463Multiple Airlines
Booking Insights

Price, demand and travel trends for Cali to Santo Domingo flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from Cali to Santo Domingo?

Round-trip flights from Cali to Santo Domingo typically range from $387 to $471. The lowest price found in the past 5 days was $423, on Copa Airlines.

What's the cheapest day of the week to fly from Cali to Santo Domingo?

Based on deals KAYAK users found in the last 12 months, Friday is the cheapest day of the week to fly from Cali to Santo Domingo. It’s 2% cheaper than the average day, while Sunday is the most expensive, with prices 15% higher.

What’s the cheapest month to fly from Cali to Santo Domingo?

•February is the cheapest month to fly from Cali to Santo Domingo at $352 round-trip.
•July ($451) and December ($437) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 28% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

When are flights from Cali to Santo Domingo the cheapest?

Flights from Cali to Santo Domingo are cheapest 17 weeks before departure. Booking in this window typically costs about 17% less than the average last-minute fare (within 2 weeks of the flight), based on KAYAK data.

Find deals

Key details for Cali to Santo Domingo flights

Low season

March

Cheapest flight

$333
Beat the crowds with an average 30% drop in travelers.
The most popular month to fly with an average 45% increase in travelers.
One-way flight from Cali to Santo Domingo

When to book flights from Cali to Santo Domingo

Are your dates flexible? Find out the best times to travel from Cali to Santo Domingo based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Cali to Santo Domingo flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from Cali to Santo Domingo?

    Only Economy Class is available on flights from Cali to Santo Domingo.

  • How long is a flight from Cali to Santo Domingo?

    A nonstop flight from Cali to Santo Domingo takes 00m, covering 1,123 miles.

  • Do I need a passport to fly from Cali to Santo Domingo?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • How much should I expect to pay for a Cali to Santo Domingo flight?

    Round-trip flights from Cali to Santo Domingo range from $387 to $471, with an average of $409 over the past 12 months. Anything below $387 counts as a good deal.

  • How expensive are last-minute Cali to Santo Domingo flights?

    Last-minute fares on this route (booked within two weeks of departure) run 14% above the $409 route average. Book 17 weeks before departure for the lowest fares.

  • Have flight prices from Cali to Santo Domingo changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $423 to $1,787. That means the highest observed fare was about 4x higher than the lowest one.

  • How are flight prices from Cali to Santo Domingo looking right now?

    One-way fares from Cali to Santo Domingo are currently higher than usual. Average one-way flight prices are about $503, which is 84% above the typical average for this route.

  • What car rental options are available at Santo Domingo Las Americas Airport (SDQ)?

    Santo Domingo Las Americas Airport (SDQ) hosts 5 major car rental companies, with daily rates averaging $31 for economy cars. Top options include:

    • Zezgo
    • America Car Rental
    • JUMBO CAR
    • Infinity Car Rental
    • Final Rentals

  • Which airports can I use when flying from Cali to Santo Domingo?

    Flights from Cali to Santo Domingo usually depart from Cali Alfonso B. Aragon Intl (CLO) and arrive at Santo Domingo Las Americas (SDQ).

  • Which airports do connecting flights from Cali to Santo Domingo pass through?

    One-stop flights from Cali to Santo Domingo most commonly connect through:

    • Panama City Tocumen Intl (PTY) - 62% of one-stop connections
    • Bogotá El Dorado (BOG) - 35% of one-stop connections
    • Medellín Jose Maria Cordova Intl (MDE) - 3% of one-stop connections

  • Can I save money by using flexible dates for flights from Cali to Santo Domingo?

    Yes. Flexible dates can save you up to 15% on flights from Cali to Santo Domingo. Friday is the cheapest departure day at $401 round-trip on average, while Sunday is the most expensive at $471, a difference of $70.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • How much time can I save by choosing a different layover airport from Cali to Santo Domingo?

    Flying via Panama City Tocumen Intl (PTY) gives the shortest average 1-stop total travel time at 6h 19m, compared with 6h 21m via Bogotá El Dorado (BOG) and 9h 23m via Medellín Jose Maria Cordova Intl (MDE).

  • What is the time difference between Cali and Santo Domingo?

    Santo Domingo is 1 hour ahead of Cali (Atlantic Time vs Colombia Time). Plan for the time shift when scheduling connections or first-day activities.

  • What popular places can I visit in Santo Domingo?

    Some of the most popular sights in Santo Domingo are Catedral Primada de América, Centro Olimpico Juan Pablo Duarte and Palacio de los Deportes Virgilio Travieso Soto. These are among the most viewed places in Santo Domingo on KAYAK.

Your guide to booking Cali to Santo Domingo flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Friday departure and avoid flying on Sunday. On this route, Friday flights average $401, about $70 less than Sunday fares (15% savings) based on the last 12 months.
  • For the best chance at a low fare, aim to book around 17 weeks before you fly. On this route, that window historically saves about 17% versus last-minute pricing (KAYAK booking data, last 12 months).
  • If you can choose when to travel, plan your Cali to Santo Domingo trip for February. Fares historically average $352 round-trip in that month - typically $99 less than the most expensive month, which is July (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Santo Domingo Las Americas Airport.

    • Hampton by Hilton Santo Domingo Airport

More options for your flight from Cali to Santo Domingo

Complete your trip to Santo Domingo with a hotel stay or car rental

Car rentals in Santo Domingo
Hotels in Santo Domingo
Vacations in Santo Domingo