$145 Find Cheap Flights from Charleston to Florida Keys - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Charleston to Florida Keys departing on 9/5. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Charleston to Florida Keys

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Miami
Miami1 stop$290
Key West
Key West1 stop$146
Miami
Miami1 stop$290
Key West
Key West1 stop$146

Book Cheap Charleston to Florida Keys Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Charleston to Florida Keys that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Charleston to Florida Keys

Mon, Aug 17 - Thu, Aug 20
Breeze Airways Logo
10:59 am - 12:34 pm
CRW
-
EYW
25h 35m
1 stop
Breeze Airways Logo
7:53 pm - 10:19 am
EYW
-
CRW
14h 26m
1 stop
$146Breeze Airways
Sun, Aug 16 - Thu, Aug 20
Breeze Airways Logo
2:45 pm - 11:27 am
CRW
-
EYW
20h 42m
1 stop
Breeze Airways Logo
7:53 pm - 10:19 am
EYW
-
CRW
14h 26m
1 stop
$162Breeze Airways
Sun, Aug 23 - Thu, Aug 27
Breeze Airways Logo
2:45 pm - 11:27 am
CRW
-
EYW
20h 42m
1 stop
Breeze Airways Logo
7:53 pm - 10:19 am
EYW
-
CRW
14h 26m
1 stop
$182Breeze Airways
Sun, Aug 30 - Thu, Sep 3
Breeze Airways Logo
2:45 pm - 11:27 am
CRW
-
EYW
20h 42m
1 stop
Breeze Airways Logo
7:53 pm - 10:19 am
EYW
-
CRW
14h 26m
1 stop
$221Breeze Airways
Sat, Sep 12 - Wed, Sep 16
Delta Logo
6:00 am - 10:46 am
CRW
-
EYW
4h 46m
1 stop
Delta Logo
7:40 am - 1:53 pm
EYW
-
CRW
6h 13m
1 stop
$260Delta
Sat, Sep 12 - Sat, Sep 19
American Airlines Logo
4:09 pm - 9:51 pm
CRW
-
MIA
5h 42m
1 stop
American Airlines Logo
8:52 am - 3:39 pm
MIA
-
CRW
6h 47m
1 stop
$290American Airlines
Sat, Jan 23 - Sat, Jan 30
American Airlines Logo
12:24 pm - 6:01 pm
CRW
-
EYW
5h 37m
1 stop
American Airlines Logo
7:08 am - 11:54 am
EYW
-
CRW
4h 46m
1 stop
$318American Airlines
Wed, Dec 2 - Sat, Dec 5
American Airlines Logo
8:15 am - 4:13 pm
CRW
-
EYW
7h 58m
1 stop
American Airlines Logo
8:00 am - 12:37 pm
EYW
-
CRW
4h 37m
1 stop
$318American Airlines
Fri, Aug 28 - Fri, Sep 4
Delta Logo
2:52 pm - 7:57 pm
CRW
-
EYW
5h 05m
1 stop
Delta Logo
11:48 am - 6:06 pm
EYW
-
CRW
6h 18m
1 stop
$338Delta
Tue, Aug 25 - Mon, Aug 31
Delta Logo
11:07 am - 5:20 pm
CRW
-
EYW
6h 13m
1 stop
Delta Logo
6:15 pm - 11:31 pm
EYW
-
CRW
5h 16m
1 stop
$338Delta
Booking Insights

KAYAK's insights & trends for Charleston to Florida Keys flights

Get data-powered insights and trends into flights from Charleston to Florida Keys to help you find the cheapest flights, the best time to fly and much more.

Can I save money by flying with a layover from Charleston to Florida Keys?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $345, prices are generally cheapest when you fly direct.

What is the cheapest month to fly from Charleston to Florida Keys?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Charleston to Florida Keys, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Charleston to Florida Keys is October, when tickets cost $323 (return) on average. On the other hand, the most expensive months are June and April, when the average cost of round-trip tickets is $606 and $523 respectively.

Good to know

Low season

July

Cheapest flight

$145
Best time to beat the crowds but there is an average 29% increase in price.
Most popular time to fly with an average 31% increase in price.
Flight from Charleston to Miami

FAQs - booking Florida Keys flights

  • How does KAYAK find such low prices on flights from Charleston to Florida Keys?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Charleston to Florida Keys.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Charleston to Florida Keys?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Charleston to Florida Keys is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Charleston to Florida Keys?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Charleston to Florida Keys with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Charleston to Florida Keys?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Charleston to Florida Keys up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Charleston to Florida Keys

 
See real verified KAYAK customer reviews for airlines flying from Charleston to Florida Keys. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Charleston to Florida Keys? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
DeltaOverall score based on 8497 reviews
7.2Food
7.8Comfort
8.5Crew
7.8Entertainment
8.1Boarding
Airline reviews

We were skipped when the snack cart passed and then the attendant said we weren’t . I am disabled and was in a row toward the back of the plane which was very difficult for me to navigate. Disabled people should not be forced to walk the plank.

6.0 GoodLaura, Jul 2026
JFK - MCO
Read more Delta reviews

We were skipped when the snack cart passed and then the attendant said we weren’t . I am disabled and was in a row toward the back of the plane which was very difficult for me to navigate. Disabled people should not be forced to walk the plank.

Flight was delayed and then "they did not have time to load food". No snack or drink at all for 1.5 how flight. Somebody wasn't prepared.

It is usually very pleasant. Good service for the price, international flights are even better

New high end luggage ruined/zippers broken, items missing. All happened on return flight from msp to mso. Do better! Not store bought luggage but high end personalized ogio custom embroidered luggage. Total slap in the face ontop of an extra luggage fee that took me 3 hrs on chat to resolve.

Third flight in two months where the crew was not there. Comfort seating does not guarantee overhead bin space. Passengers with children are allowed on the plane first - if you are flying to and from Orlando, this means half the plane has boarded before you get on. And somehow all the bin space is taken up. 3 out of 5 flights have had issues with equipment or procedure. Some of these instances caused the flight to be delayed because of a "nuisance" light. One time it was a bag that had been brought on board but did not belong to anyone so we had to return to the gate. Last night we were told the "AC" on the plane doesn't work well and we're 10th for take off- because the crew was late - and that it will get cool when we're in the air. Not sure if this is usual, but I didn't think flight crew could jump seat in first class. Movie and TV selection has not been refreshed for several months- flying one to two round trips each month easily exhausts the list of content.

Definitely a southern flavor. Cordiality was evident even though no drinks or snacks were served.

No service flight that took 5 hrs and a stop at an unscheduled airport. Crew and pilots did their jobs

I continue to be satisfied with Delta’s excellent service out of LGA. The digit id works well and gets me through security in no time. Whenever possible, I choose Delta.

Was revoked with Jet Blue due to delay from Kenya Air

Typically I give delta excellent reviews. Our flight was delayed 2hrs, I was one of the fortunate ones who were able to get to my connecting flight. Also, annoying that on the connecting flight boarding personnel make me put away a small bag into my carryon. It small enough to put in back pocket seat, why hold me and the line up to just push it into my carryon.

Bad experience going to DFW with an IT outage then bad on the way back with a nearly 5 hour delay that’s started as maintenance then caused us to wait further due to weather - which would not have happened if we had left on time.

Quick flight. No time to stress over it. Over before it begins.

Very good, boarded and took off on time and landed early

Delayed boarding because a flight attendant couldn't find the gate...sat on the plane for over an hour at the gate because AA couldn't get one of the planes behind us to move

It was awful. My first flight was delayed and as a consequence I lost my second flight to Greensboro. I did not know what to do so I rebook myself a flight to Charlotte . It was very inconvenient I not to have anybody form corporate assisting me either from PwC or from kayak . It is a very disappointing experience that American did not wait 1 minute or told me to rebook before making the first flight

The departure and arrival was on time. The fact that I could load my boarding tickets on the American airlines app.

Horrible experience, delays after delays. A flight that should arrive 11:50pm just landed past 1 am, and another 30min waiting for the baggage to come out. Very disappointing.

The flight was delayed significantly. Communication during the flight was abrupt and caused some panic as we were navigating turbulence. It was also too loud and every announcement felt startling. The flight attendants did not offer any assurances and I felt unsettled most of the flight. The seats, floor and tray table was very dirty. The seat next to me was broken and the passenger sitting there was very uncomfortable. He had a spring in his back and his seat made terrible squeaking noises through the flight.

My experience with American Airlines was great. Unfortunately my stroller was not located and has not been given to me and or reached out in return for in regard to information.

The Charleston, WV airport was cute. Very good staff and small enough to feel comfortable. The plane had more leg room than bigger planes. Much more comfortable.

Everything you need to know for your flight to Florida Keys

Information on your arrival and departure airports