$138 Find Cheap Flights from Charleston to Florida Keys

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Charleston to Florida Keys departing on 5/3. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Florida Keys

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Charleston to Florida Keys, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Charleston to Florida Keys, as well as popular online travel agencies
Travelers love KAYAK
41’299’237 searches in the past 7 days on KAYAK

Save 23% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Charleston to Florida Keys

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Miami
Miami1 stop$258
Key West
Key West1 stop$140
Miami
Miami1 stop$258
Key West
Key West1 stop$140

Book Cheap Charleston to Florida Keys Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Charleston to Florida Keys that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Charleston to Florida Keys

Sun, Mar 22 - Thu, Mar 26
Breeze Airways Logo
8:52 pm - 9:09 am
CRW
-
EYW
12h 17m
1 stop
Breeze Airways Logo
11:01 am - 8:12 pm
EYW
-
CRW
9h 11m
1 stop
$140Breeze Airways
Fri, Apr 24 - Sat, May 2
Delta Logo
7:10 pm - 12:54 am
CRW
-
MIA
5h 44m
1 stop
Delta Logo
8:05 am - 3:20 pm
MIA
-
CRW
7h 15m
1 stop
$258Delta
Fri, Apr 24 - Tue, Apr 28
American Airlines Logo
6:11 pm - 10:51 pm
CRW
-
MIA
4h 40m
1 stop
American Airlines Logo
6:37 pm - 11:03 pm
MIA
-
CRW
4h 26m
1 stop
$259American Airlines
Sun, Mar 22 - Thu, Mar 26
Multiple Airlines Logo
8:52 pm - 1:37 pm
CRW
-
EYW
16h 45m
2 stops
Multiple Airlines Logo
11:01 am - 8:12 pm
EYW
-
CRW
9h 11m
1 stop
$277Multiple Airlines
Wed, Apr 1 - Tue, Apr 7
American Airlines Logo
6:08 pm - 11:43 pm
CRW
-
MIA
5h 35m
1 stop
American Airlines Logo
5:30 pm - 11:03 pm
MIA
-
CRW
5h 33m
1 stop
$283American Airlines
Tue, Mar 24 - Sat, Mar 28
Delta Logo
10:59 am - 5:21 pm
CRW
-
MIA
6h 22m
1 stop
Delta Logo
6:00 am - 10:19 am
MIA
-
CRW
4h 19m
1 stop
$288Delta
Sat, Apr 25 - Wed, Apr 29
American Airlines Logo
6:11 pm - 10:36 pm
CRW
-
EYW
4h 25m
1 stop
American Airlines Logo
5:03 pm - 10:00 pm
EYW
-
CRW
4h 57m
1 stop
$289American Airlines
Sat, Apr 25 - Wed, Apr 29
American Airlines Logo
6:11 pm - 10:36 pm
CRW
-
EYW
4h 25m
1 stop
American Airlines Logo
11:24 am - 10:00 pm
EYW
-
CRW
10h 36m
2 stops
$295American Airlines
Fri, Apr 17 - Thu, Apr 23
American Airlines Logo
6:11 pm - 10:51 pm
CRW
-
MIA
4h 40m
1 stop
American Airlines Logo
5:17 pm - 10:00 pm
MIA
-
CRW
4h 43m
1 stop
$303American Airlines
Tue, Mar 24 - Sat, Mar 28
Delta Logo
10:59 am - 5:21 pm
CRW
-
MIA
6h 22m
1 stop
Delta Logo
6:00 am - 10:19 am
MIA
-
CRW
4h 19m
1 stop
$308Delta
Booking Insights

KAYAK's insights & trends for Charleston to Florida Keys flights

Get data-powered insights and trends into flights from Charleston to Florida Keys to help you find the cheapest flights, the best time to fly and much more.

Can I save money by flying with a layover from Charleston to Florida Keys?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $377, prices are generally cheapest when you fly direct.

What is the cheapest month to fly from Charleston to Florida Keys?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Charleston to Florida Keys, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Charleston to Florida Keys is December, when tickets cost $253 (return) on average. On the other hand, the most expensive months are April and March, when the average cost of round-trip tickets is $575 and $480 respectively.

Good to know

Low seasonFebruary
Cheapest flight$138
Best time to beat the crowds but there is an average 2% increase in price.
Most popular time to fly with an average 27% increase in price.
Flight from Charleston to Miami

FAQs - booking Florida Keys flights

  • How does KAYAK find such low prices on flights from Charleston to Florida Keys?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Charleston to Florida Keys.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Charleston to Florida Keys?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Charleston to Florida Keys is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Charleston to Florida Keys?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Charleston to Florida Keys with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Charleston to Florida Keys?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Charleston to Florida Keys up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Charleston to Florida Keys

 
See real verified KAYAK customer reviews for airlines flying from Charleston to Florida Keys. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Charleston to Florida Keys? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8278 reviews
7.8Entertainment
8.5Crew
8.1Boarding
7.2Food
7.9Comfort
Airline reviews

The whole experience was excellent. As it most often is with Delta

10.0 ExcellentRay, Mar 2026
LGA - MCO
Read more Delta reviews

The whole experience was excellent. As it most often is with Delta

We waited an hour on the runway to get a gate in Orlando

Flight was delayed by 3-hours and their fix was… complimentary pretzels.

The staff on board and gate was nice - a welcome change from the usual. We also arrived early, which was a great benefit, given that it takes 30 minutes plus to get bags at SRQ.

They took all carry-on luggage from Groups 6 -9 - I was group 5 and waiting in line to board - they made me check my luggage too. That then went to baggage claim and delayed departure from the airport. There was overhead room in my seating area - Delta over reacted. Also, had a gentleman next to me that took up 1/2 my seat.

Sorry I didn't realize I was writing a review for each leg. Please see my previous review - it applies to the entire flight, not just a single leg.

boarded at 5:30 pm, pushed away from gate at 6pm ... takeoff was not until ~6:45pm; disappointing

Paid for wifi that didn't work. No plug in seat to work. No entertainment.

The flight was delayed and oversold. I volunteered to give up my seat for compensation. Thinking I could get a good night's sleep instead of arriving home at 2 am. It took over an hour to get the new reservation confirmed, three different gate attendants, and two red coats. It took even longer to confirm the overnight hotel, and when I arrived, the line was 45 minutes long, with two people checking in, and at least 15 people slowly, very slowly—no food except frozen convenience food, no coupon for food from airlines. Slept, headed back to the airport, and that flight had an equipment change and a gate change just as they were about to board. It took an additional hour to board as they cleaned the plane from storage.

Comfort Plus seat 11E seemed smaller than prior flights. The movie selection is good. Watched most of the most recent Tron movie. I'll watch the remaining part later as my movie is saved in the Delta Seatback Experience.

Mechanical issue delayed us 2hrs and then once we landed sat on tarmac for 30mins because someone left a vehicle in front of the gaye

Plane from partner PSA was filthy. Plastic needs to be thoroughly cleaned. Really disgusting to look at and wonder about cleanliness of parts less visible.

Flight delay for mechanical. Inbound arrived on time. No one said why mechanical delay.

It was a train wreck but on an airplane. First off, flight was delayed then we board only to hear two announcements, First weather delays in Orlando and second backup battery warning on emergency lights. After sitting on the plane for almost 2 hours they have us deplane due to the maintenance issue. We were told they were getting another plane. In the mean time, I notice another American- Orlando flight and ask the gate agent if I can switch. He says he cant help me and I'd have to walk to A13 from A37. Really!? I get down there and get a seat only to get an announcement my original flight was RE-boarding. The Then inflight there's no communication and I notice on flightaware were circling over the Gulf of America. I call the flight attendant and of course she has no clue and apparently 5m later the pilot finally tells us about another delay. Why does American always have these service and delay issues? They are my LAST choice in flights now!

Flight boarded, departed and landed on time. Excellent service from flight attendant in FIRST

Flight to Tampa was delayed taking off due to plane arriving late but no other issues

We missed our flight and got stranded in Miami where we had to rent a hotel we could not afford. they would not work with us because they said it was weather related even though the gate attendant said it was not. I could go on but trying to get satisfaction has wore me down, which I believe is the intent. My only solution is to never fly AA again.

The flight was really crowded. Flight attendants were just ok.

Didn't get a seat assignment until the last minute even though i picked a seat.

Flight was on time and the meal and service were good.

Everything you need to know for your flight to Florida Keys

Information on your arrival and departure airports