$122 Find Cheap Flights from Charleston to Florida Keys - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Charleston to Florida Keys departing on 8/13. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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1 adult, Economy, 0 bags

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Cheap Flights from Charleston to Florida Keys

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Miami
Miami1 stop$280
Key West
Key West1 stop$279
Miami
Miami1 stop$280
Key West
Key West1 stop$279

Book Cheap Charleston to Florida Keys Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Charleston to Florida Keys that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Charleston to Florida Keys

Sat, Nov 14 - Fri, Nov 20
Delta Logo
3:25 pm - 7:43 pm
CRW
-
EYW
4h 18m
1 stop
Delta Logo
11:45 am - 5:53 pm
EYW
-
CRW
6h 08m
1 stop
$279Delta
Wed, Jul 29 - Sat, Sep 19
Delta Logo
2:45 pm - 9:59 pm
CRW
-
MIA
7h 14m
1 stop
Delta Logo
6:00 am - 10:27 am
MIA
-
CRW
4h 27m
1 stop
$280Delta
Sat, Nov 14 - Sat, Nov 21
Delta Logo
3:25 pm - 7:43 pm
CRW
-
EYW
4h 18m
1 stop
Delta Logo
6:00 pm - 10:39 pm
EYW
-
CRW
4h 39m
1 stop
$298Delta
Tue, Oct 27 - Mon, Nov 2
United Airlines Logo
1:50 pm - 10:21 pm
CRW
-
MIA
8h 31m
1 stop
United Airlines Logo
7:00 am - 1:15 pm
MIA
-
CRW
6h 15m
1 stop
$323United Airlines
Wed, Aug 19 - Sat, Aug 22
American Airlines Logo
5:14 pm - 9:59 pm
CRW
-
MIA
4h 45m
1 stop
American Airlines Logo
6:38 pm - 10:59 pm
MIA
-
CRW
4h 21m
1 stop
$330American Airlines
Wed, Dec 2 - Sat, Dec 5
Delta Logo
3:25 pm - 7:43 pm
CRW
-
EYW
4h 18m
1 stop
Delta Logo
6:00 pm - 10:39 pm
EYW
-
CRW
4h 39m
1 stop
$339Delta
Sun, Sep 27 - Sat, Oct 3
Delta Logo
6:53 pm - 12:55 am
CRW
-
MIA
6h 02m
1 stop
Delta Logo
6:00 am - 10:27 am
MIA
-
CRW
4h 27m
1 stop
$342Delta
Wed, Dec 2 - Sat, Dec 5
American Airlines Logo
8:15 am - 4:13 pm
CRW
-
EYW
7h 58m
1 stop
American Airlines Logo
4:53 pm - 10:54 pm
EYW
-
CRW
6h 01m
1 stop
$351American Airlines
Fri, Oct 30 - Sun, Nov 8
United Airlines Logo
1:50 pm - 10:21 pm
CRW
-
MIA
8h 31m
1 stop
United Airlines Logo
7:00 am - 1:15 pm
MIA
-
CRW
6h 15m
1 stop
$379United Airlines
Wed, Jul 15 - Sun, Jul 19
Breeze Airways Logo
2:22 pm - 7:13 pm
CRW
-
EYW
28h 51m
2 stops
Breeze Airways Logo
7:53 pm - 10:19 am
EYW
-
CRW
14h 26m
1 stop
$423Breeze Airways
Booking Insights

KAYAK's insights & trends for Charleston to Florida Keys flights

Get data-powered insights and trends into flights from Charleston to Florida Keys to help you find the cheapest flights, the best time to fly and much more.

Can I save money by flying with a layover from Charleston to Florida Keys?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $418, prices are generally cheapest when you fly direct.

What is the cheapest month to fly from Charleston to Florida Keys?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Charleston to Florida Keys, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Charleston to Florida Keys is November, when tickets cost $90 (return) on average. On the other hand, the most expensive months are June and July, when the average cost of round-trip tickets is $336 and $298 respectively.

Good to know

Low seasonJuly
Cheapest flight$122
Best time to beat the crowds with an average 4% drop in price.
Most popular time to fly with an average 33% increase in price.
Flight from Charleston to Key West

FAQs - booking Florida Keys flights

  • How does KAYAK find such low prices on flights from Charleston to Florida Keys?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Charleston to Florida Keys.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Charleston to Florida Keys?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Charleston to Florida Keys is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Charleston to Florida Keys?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Charleston to Florida Keys with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Charleston to Florida Keys?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Charleston to Florida Keys up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Charleston to Florida Keys

 
See real verified KAYAK customer reviews for airlines flying from Charleston to Florida Keys. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Charleston to Florida Keys? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
DeltaOverall score based on 8454 reviews
7.8Entertainment
7.8Comfort
7.2Food
8.5Crew
8.1Boarding
Airline reviews

New high end luggage ruined/zippers broken, items missing. All happened on return flight from msp to mso. Do better! Not store bought luggage but high end personalized ogio custom embroidered luggage. Total slap in the face ontop of an extra luggage fee that took me 3 hrs on chat to resolve.

2.0 MediocreAnonymous, Jun 2026
MSP - MCO
Read more Delta reviews

New high end luggage ruined/zippers broken, items missing. All happened on return flight from msp to mso. Do better! Not store bought luggage but high end personalized ogio custom embroidered luggage. Total slap in the face ontop of an extra luggage fee that took me 3 hrs on chat to resolve.

Third flight in two months where the crew was not there. Comfort seating does not guarantee overhead bin space. Passengers with children are allowed on the plane first - if you are flying to and from Orlando, this means half the plane has boarded before you get on. And somehow all the bin space is taken up. 3 out of 5 flights have had issues with equipment or procedure. Some of these instances caused the flight to be delayed because of a "nuisance" light. One time it was a bag that had been brought on board but did not belong to anyone so we had to return to the gate. Last night we were told the "AC" on the plane doesn't work well and we're 10th for take off- because the crew was late - and that it will get cool when we're in the air. Not sure if this is usual, but I didn't think flight crew could jump seat in first class. Movie and TV selection has not been refreshed for several months- flying one to two round trips each month easily exhausts the list of content.

Definitely a southern flavor. Cordiality was evident even though no drinks or snacks were served.

No service flight that took 5 hrs and a stop at an unscheduled airport. Crew and pilots did their jobs

I continue to be satisfied with Delta’s excellent service out of LGA. The digit id works well and gets me through security in no time. Whenever possible, I choose Delta.

Was revoked with Jet Blue due to delay from Kenya Air

Overall Good! The weather delayed our takeoff from Atlanta and our arrival in Miami! If Mother Nature can mess up a flight she will do it every time!

N Everything was perfect from boarding to assistance to baggage in Tampa

Snacks and included beverages were appreciated. Boarding went smoothly. Plenty of overhead bin space. Seats get very uncomfortable after a couple of hours. After waiting 10 painful minutes for my walker, a very nice Delta guest agent pushed me in a wheelchair to the gate. It was finally delivered to me after another 15 minutes . Our checked bag was on the carousel long b4 I was able to retrieve it. Fortunately it was still there but somewhere along the way the straps we used to secure it were removed and and were not reattached. Wish I had made note of the agents name.

Typically I give delta excellent reviews. Our flight was delayed 2hrs, I was one of the fortunate ones who were able to get to my connecting flight. Also, annoying that on the connecting flight boarding personnel make me put away a small bag into my carryon. It small enough to put in back pocket seat, why hold me and the line up to just push it into my carryon.

Horrible experience, delays after delays. A flight that should arrive 11:50pm just landed past 1 am, and another 30min waiting for the baggage to come out. Very disappointing.

The flight was delayed significantly. Communication during the flight was abrupt and caused some panic as we were navigating turbulence. It was also too loud and every announcement felt startling. The flight attendants did not offer any assurances and I felt unsettled most of the flight. The seats, floor and tray table was very dirty. The seat next to me was broken and the passenger sitting there was very uncomfortable. He had a spring in his back and his seat made terrible squeaking noises through the flight.

My experience with American Airlines was great. Unfortunately my stroller was not located and has not been given to me and or reached out in return for in regard to information.

It was awful. The communication between corporate and the crew on the ground left more to be desired. The crew even said that Corporate was waiting on answers because they themselves didn't know. Every hour, there was a new excuse. I also understood that passengers were angry, but the crew should have done a better job at crowd control. There was a racial exchange between passengers that could've been avoided has the crew acted sooner.

We sat on plane at gate delayed without communication as to why we were just sitting there

Flight was delayed by 6 hours... the level of incompetence was truly astounding. I won't be flying American Airlines again. I don't care if AA is direct and there is a layover with another airline, I'll take the layover.

The Charleston, WV airport was cute. Very good staff and small enough to feel comfortable. The plane had more leg room than bigger planes. Much more comfortable.

Little time between flight from Dallas to flight to Gainesville. We chose this one, 43 minutes between, because the price for a connection with at least an hour between, was so much higher. Had to ask passengers on the Dallas flight to please allow us to deplane ahead of them. The economy passengers allowed this. We had to walk very fast to the next gate, 35 gates away. Thankfully all in the same terminal. Getting to the small Gainesville plane was a little confusing as you enter an area that is boarding many small planes at the same time. We stood in the wrong line for about 15 seconds before realizing it was not our Gainesville flight. Since I had boarded at this gate in the past, I knew to check the signs carefully so we weren’t lost. The first class seat experience was wonderful. I really enjoyed the upgrade. We were offered an alcohol drink as soon as we sat down. I got something different but it was a great gesture especially since we really had to hurry to make the flight. We had packed expecting we might miss this connection, but made it. Our luggage didn’t miss the flight. American Airlines delivered our bags to our home the next day. That was very convenient!

The plane was large, not full, but one with 3 seats near each window and 4 in a row in the middle of the plane. There were screens on the backs of the seats for entertainment and information. To use the entertainment one needs ear plugs that physically plug into the screen. My husband had some he let me use as I only had blue tooth type. The stewards gave out some headphones to some, but when my neighbor asked for some, the steward said no. So maybe they ran out? Idk. Bring the old kind of headphones or earbuds if you want entertainment in case this is the type of entertainment offered. We had a very tight connection in Miami. 43 minutes. The other economy passengers allowed us to get ahead of them because I asked if we could since we were near boarding time for our next flight and 35 gates away. They were extremely kind. First class wasn’t going to allow us to pass through. We did make the next flight. Our baggage didn’t, but they were delivered to us the next day and we were prepared with essentials in our carry on packs.

Flight left on time. Captain provided relevant announcements. We had to wait 45 minutes to desembark due to the ramp closed because of lightening.

Everything you need to know for your flight to Florida Keys

Information on your arrival and departure airports