$228 Find Cheap Flights from Denver to Panama

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Denver to Panama departing on 9/28. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Denver to Panama

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Panama City
Panama Citynonstop$510
David
David1 stop$500
Panama City
Panama Citynonstop$510
David
David1 stop$500

Book Cheap Denver to Panama Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Denver to Panama that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Denver to Panama

Thu, Sep 3 - Mon, Sep 7
Copa Airlines Logo
10:43 pm - 5:33 am
DEN
-
PTY
5h 50mnonstop
Copa Airlines Logo
12:56 pm - 6:11 pm
PTY
-
DEN
6h 15mnonstop
$510Copa Airlines
Fri, Oct 16 - Thu, Oct 22
United Airlines Logo
5:00 am - 2:14 pm
DEN
-
PTY
8h 14m
1 stop
United Airlines Logo
10:00 am - 8:08 pm
PTY
-
DEN
11h 08m
1 stop
$525United Airlines
Thu, Sep 3 - Sat, Sep 12
Copa Airlines Logo
10:43 pm - 5:33 am
DEN
-
PTY
5h 50mnonstop
Copa Airlines Logo
12:56 pm - 6:11 pm
PTY
-
DEN
6h 15mnonstop
$528Copa Airlines
Fri, Oct 16 - Tue, Oct 20
American Airlines Logo
4:21 pm - 2:00 pm
DEN
-
PTY
20h 39m
2 stops
American Airlines Logo
3:35 pm - 8:24 am
PTY
-
DEN
17h 49m
2 stops
$529American Airlines
Fri, Oct 16 - Mon, Oct 19
Copa Airlines Logo
5:00 am - 6:37 pm
DEN
-
PTY
12h 37m
1 stop
Copa Airlines Logo
3:30 pm - 6:47 am
PTY
-
DEN
16h 17m
1 stop
$535Copa Airlines
Tue, Sep 15 - Tue, Sep 29
American Airlines Logo
1:17 pm - 12:24 pm
DEN
-
PTY
22h 07m
2 stops
American Airlines Logo
1:16 pm - 9:55 am
PTY
-
DEN
21h 39m
2 stops
$538American Airlines
Tue, Oct 13 - Mon, Oct 19
Delta Logo
12:59 am - 12:56 pm
DEN
-
PTY
10h 57m
1 stop
Delta Logo
2:21 pm - 11:49 pm
PTY
-
DEN
10h 28m
1 stop
$545Delta
Sat, Oct 17 - Sat, Nov 7
Copa Airlines Logo
10:43 pm - 5:33 am
DEN
-
PTY
5h 50mnonstop
Copa Airlines Logo
12:56 pm - 5:02 pm
PTY
-
DEN
6h 06mnonstop
$546Copa Airlines
Sat, Oct 17 - Sat, Nov 7
American Airlines Logo
3:12 pm - 2:00 pm
DEN
-
PTY
21h 48m
2 stops
American Airlines Logo
2:43 pm - 11:01 pm
PTY
-
DEN
10h 18m
1 stop
$549American Airlines
Fri, Sep 18 - Sun, Sep 20
American Airlines Logo
1:21 pm - 12:16 pm
DEN
-
PTY
21h 55m
2 stops
American Airlines Logo
1:16 pm - 10:00 am
PTY
-
DEN
21h 44m
2 stops
$554American Airlines
Booking Insights

KAYAK's insights & trends for Denver to Panama flights

Get data-powered insights and trends into flights from Denver to Panama to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest Denver to Panama flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to Panama from Denver found in the last 5 days was to Panama City, at $400 round-trip. The most popular route is from Denver (DEN) to Panama City (PTY), and the cheapest round-trip airline ticket found on this route in the last 5 days was $400.

What is the cheapest time of day to fly to Panama?

The average price for all round-trip flights from Denver to Panama depending on the time of departure, clicked by users on KAYAK in the last 2 weeks.

The cheapest time of day to fly to Panama is generally at night, when round-trip flights cost $596 on average. The most expensive time of day to fly to Panama is generally at night, which is peak travel time and where the average cost of a ticket is $596.

Can I save money by flying with a layover from Denver to Panama?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $697, prices are generally cheapest when you fly direct.

What is the cheapest month to fly from Denver to Panama?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Denver to Panama, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Denver to Panama is March, when tickets cost $234 (return) on average. On the other hand, the most expensive months are July and November, when the average cost of round-trip tickets is $518 and $512 respectively.

What’s the cheapest day of the week to fly from Denver to Panama?

The average price of all round-trip flights from Denver to Panama clicked on KAYAK for each day over the last 12 months.

If you are looking for a flight deal from Denver to Panama, look for departures on Tuesdays and avoid leaving on a Sunday, as it's usually the priciest day. When flying back from Panama, Monday is the cheapest day to fly and Friday is the most expensive.

How far in advance should I book a flight from Denver to Panama?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Denver to Panama, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Denver to Panama, you should book around 4 weeks before departure, which saves you about 21% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 22 weeks before departure.

Good to know

Low seasonSeptember
Cheapest flight$228
Best time to beat the crowds with an average 14% drop in price.
Most popular time to fly with an average 14% increase in price.
Flight from Denver to Panama City

FAQs - booking Panama flights

  • How does KAYAK find such low prices on flights from Denver to Panama?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Denver to Panama.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Denver to Panama?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Denver to Panama is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Denver to Panama?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Denver to Panama with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Denver to Panama?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Denver to Panama up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Denver to Panama

 
Need help choosing which airline to fly with from Denver to Panama? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
Copa AirlinesOverall score based on 1566 reviews
6.8Entertainment
7.7Boarding
7.4Comfort
8.1Crew
6.9Food
Airline reviews

They didn’t have any headphones for the entertainment screen and their USB port didn’t accommodate a USB-C for more modern phones. The food was just ok. The staff was friendly but the seats were very uncomfortable for a full flight.

6.0 GoodAnonymous, May 2026
SCL - PTY
Read more Copa Airlines reviews

They didn’t have any headphones for the entertainment screen and their USB port didn’t accommodate a USB-C for more modern phones. The food was just ok. The staff was friendly but the seats were very uncomfortable for a full flight.

I had to run from the end of terminal one to the end of terminal two to make the connecting flight....probably a kilometer. No electric carts were available. I'm 76 and literally had to run to make the connection at the last minute. The connecting time was absolutely unrealistic. When Last Call was announced, I tried to get other Copa gate staff to call Gate 221 to let them know I was on my way, but they said no. I came within 1 minute of missing the flight.

I was flying business class, and the French fellow passengers were super noisy. It was not a comfortable flight. And the crew was not helpful.

Boarding was a mess, they call all priority members without distinction so gold, platinum, silver were all mixed together in a long line which defeats the purpose

Entire experience from check in to landing was amazing the flight crew was excellent and friendly. Seats were comfortable.

Boarding was confusing from staff telling going to preboard and than to group 1 Airplane was not cooling at the beginning

Avoid at all costs. My wife had to stay back on a connecting flight as her parents flight was delayed. 10 days later on the way back they cancelled all our flights. We had to rebook all four of us on the next days flight.

Friendly crew, good food options, food not the best and seats not as comfy but that’s typical.

The food is terrible I ask for water never got transport my mother we’re late and my sister from Lima was the worst waiting to long for wheelchair

Seats were awful. Media should have been included for such a long flight.

New plane was lovely. Crew customer service is always lax but expected. Kraft on time and arrived safely.

It was a short flight so I was expecting too much

Had a one hour delay due to mechanical issue. I didn’t think I’d be able to make my connecting flight, but they waited for me and greeted me when I arrived to help things run smooth.

O’hsre taxi and deboarding took 40 minutes. Needed 20 minutes extra time between connecting flights to avoid running through terminal.

Was great in general, try to respect time and excuses when slight changes have been made, appreciated!

Really hard landing... as in slammed into the runway then hit the brakes really hard ...

Putting people that close to the bathroom, where you have to look into the bathroom as people are exiting and entering was not great and the smell was also not great. I know the airlines are desperate for more chairs, but that seat is a crime.

Every staff member was professional, friendly and courteous. The pizza twist was ok. It was warm but too much dough.

one staffer was frustrated (it happen); the flight was late and the pilot mentioned they'll make amend but the snacks were the same, other than that the aircraft was clean and everything went smooth, no complaints

Wonderful in-seat entertainment with seatback screens and huge selection of quality movies. The ability to bluetooth connect headphones was amazing.

Everything you need to know for your flight from Denver to Panama

Information on your arrival and departure airports