$174 Find Cheap Flights from Denver to Panama

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Denver to Panama departing on 4/19. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Denver to Panama

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Panama City
Panama City1 stop$395
David
David1 stop$520
Panama City
Panama City1 stop$395
David
David1 stop$520

Book Cheap Denver to Panama Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Denver to Panama that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Denver to Panama

Selasa, Mac 3 - Rabu, Mac 11
Delta Logo
12:59 am - 1:50 pm
DEN
-
PTY
10h 51m
1 stop
Delta Logo
2:28 pm - 12:09 am
PTY
-
DEN
10h 41m
1 stop
$395Delta
Rabu, Mac 4 - Rabu, Mac 18
Delta Logo
12:59 am - 1:50 pm
DEN
-
PTY
10h 51m
1 stop
Delta Logo
2:28 pm - 9:26 am
PTY
-
DEN
19h 58m
1 stop
$404Delta
Ahad, Apr 26 - Rabu, Mei 6
Multiple Airlines Logo
11:05 pm - 7:20 pm
DEN
-
PTY
19h 15m
1 stop
Multiple Airlines Logo
3:10 pm - 8:27 am
PTY
-
DEN
18h 17m
2 stops
$427Multiple Airlines
Sabtu, Mei 2 - Isnin, Mei 4
Multiple Airlines Logo
11:05 pm - 2:15 pm
DEN
-
PTY
14h 10m
2 stops
Multiple Airlines Logo
9:33 pm - 10:30 am
PTY
-
DEN
13h 57m
1 stop
$438Multiple Airlines
Rabu, Apr 29 - Isnin, Mei 4
Multiple Airlines Logo
11:05 pm - 7:20 pm
DEN
-
PTY
19h 15m
1 stop
Multiple Airlines Logo
3:10 pm - 10:30 am
PTY
-
DEN
20h 20m
2 stops
$443Multiple Airlines
Selasa, Apr 28 - Rabu, Mei 6
Multiple Airlines Logo
11:05 pm - 7:20 pm
DEN
-
PTY
19h 15m
1 stop
Multiple Airlines Logo
3:10 pm - 8:27 am
PTY
-
DEN
18h 17m
2 stops
$444Multiple Airlines
Isnin, Apr 27 - Rabu, Mei 6
Multiple Airlines Logo
11:05 pm - 3:54 pm
DEN
-
PTY
15h 49m
1 stop
Multiple Airlines Logo
3:10 pm - 8:27 am
PTY
-
DEN
18h 17m
2 stops
$447Multiple Airlines
Selasa, Apr 28 - Jumaat, Mei 8
Multiple Airlines Logo
11:05 pm - 7:20 pm
DEN
-
PTY
19h 15m
1 stop
Multiple Airlines Logo
3:10 pm - 9:09 am
PTY
-
DEN
18h 59m
2 stops
$448Multiple Airlines
Selasa, Apr 21 - Selasa, Apr 28
Multiple Airlines Logo
11:05 pm - 3:54 pm
DEN
-
PTY
15h 49m
1 stop
Multiple Airlines Logo
9:33 pm - 9:40 am
PTY
-
DEN
13h 07m
1 stop
$449Multiple Airlines
Ahad, Apr 19 - Selasa, Apr 28
Multiple Airlines Logo
11:05 pm - 7:20 pm
DEN
-
PTY
19h 15m
1 stop
Multiple Airlines Logo
10:25 am - 9:40 am
PTY
-
DEN
24h 15m
1 stop
$453Multiple Airlines
Booking Insights

KAYAK's insights & trends for Denver to Panama flights

Get data-powered insights and trends into flights from Denver to Panama to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest Denver to Panama flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to Panama from Denver found in the last 72 hours was to Panama City, at $321 round-trip. The most popular route is from Denver (DEN) to Panama City (PTY), and the cheapest round-trip airline ticket found on this route in the last 72 hours was $321.

Can I save money by flying with a layover from Denver to Panama?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 1 stop layover the cheapest option at $589 on average.

What is the cheapest month to fly from Denver to Panama?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Denver to Panama, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Denver to Panama is August, when tickets cost $537 (return) on average. On the other hand, the most expensive months are December and November, when the average cost of round-trip tickets is $739 and $688 respectively.

What’s the cheapest day of the week to fly from Denver to Panama?

The average price of all round-trip flights from Denver to Panama clicked on KAYAK for each day over the last 12 months.

If you are looking for a flight deal from Denver to Panama, look for departures on Tuesdays and avoid leaving on a Sunday, as it's usually the priciest day. When flying back from Panama, Tuesday is the cheapest day to fly and Friday is the most expensive.

How far in advance should I book a flight from Denver to Panama?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Denver to Panama, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Denver to Panama, you should book around 4 weeks before departure, which saves you about 25% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 26 weeks before departure.

Good to know

Low seasonSeptember
Cheapest flight$174
Best time to beat the crowds with an average 12% drop in price.
Most popular time to fly with an average 12% increase in price.
Flight from Denver to Panama City

FAQs - booking Panama flights

  • How does KAYAK find such low prices on flights from Denver to Panama?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Denver to Panama.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Denver to Panama?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Denver to Panama is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Denver to Panama?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Denver to Panama with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Denver to Panama?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Denver to Panama up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to Panama?

    The cheapest time of day to fly to Panama is generally at night, when round-trip flights cost $584 on average. The most expensive time of day to fly to Panama is generally at night, which is peak travel time and where the average cost of a ticket is $584.

Reviews of the top 3 airlines serving from Denver to Panama

 
Need help choosing which airline to fly with from Denver to Panama? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
Copa AirlinesOverall score based on 1557 reviews
6.8Food
8.1Crew
7.4Comfort
7.8Boarding
6.8Entertainment
Airline reviews

Seats were awful. Media should have been included for such a long flight.

4.0 OkayPaul, Jan 2026
LIM - PTY
Read more Copa Airlines reviews

Seats were awful. Media should have been included for such a long flight.

There should be a warning regarding the quality of the aircraft on the website as we reserve the tickets. There was no TV or any type of screen onboard. The wifi they offer is good for nothing. Traveling 9 hours straight with kids and no type of entetainment was horrible. I wish I had been informed prior so I could buy a ticket with another airline. The food was a joke too. A very tiny portion per passenger. They also charged $100 per checked bag. With United I used to pay $60. So, fair to say that I wont be flying Copa anymore. Their aircraft was super old, outdated, no entertainment, with nearly no onboard food.

I always enjoy flying Copa. There are very few airlines where I can enjoy a comfortable sleep in-flight. The snacks weren't the best, but they sufficed. The in-flight entertainment was fantastic, and I crossed another movie off my watch list.

Very strict carry on rules meant most of the plane had to gate check their luggage. As is often the case had things that were broken because of this, but I appreciated not being charged to gate check. Otherwise good flight and great crew once on the plane

Simply as follows:- First, there was no vegetarian option for the meal Second, only 2 washrooms for the entire economy class.

I liked the meatloaf the chicken was awful but the plane was on time and got there and the staff was nice.

They were super friendly bumped me up to exit row free of charge, All flight legs were on time

Boarding was quick & efficient; they gave boarding groups due priority; staff & air crew were very cordial and helpful, pleasant flight.

Cops Airlines is fantastic! The level of care and professionalism provided by the entire crew was top rate.

the food served was an embarrassment. No connection for charging the cellphone... What a crappy airline.

Flight left on time and we arrived 25 minutes early! There was a gate available when we arrived so early on a busy Sunday afternoon! Flight attendants came around twice with the drinks cart.

Sitting on the runway after we land for almost two hours! Not sure if we should blame United or Just Dumpy Vance.

Flight was late - I was downgraded from first class to coach

United overall experience is great these days. Airport experience was very organized. Staff on flight were great. App and information as good as it gets.

Great smooth flight. Had a seating change, but that was an improvement. Thanks United Airways Crew.

Flight was good but there are way to many announcements for credit cards etc.

Crew seemed a bit cranky. No seatback screens. But boarding was efficient and on time and we arrived early.

See previous note about the passenger in Denver who threw my husband's bag out of the overhead bin in order to maker room for his own. And the flight attendant back up the new passenger.

Terrible. They wouldn't allow me on my flight on the 14th..

Impressed with the service despite turbulence because of the weather. Both flights arrived before their scheduled times.

It was an older plane. First Class was not especially roomy or comfortable. It was a short flight so there were no meal but they did offer mixed nuts which used to be normal but now is rare. Crew member was very polite and professional.

The chicken wrap was tiny ($13 for what looked like a 1/3 of a normal wrap?) and disgusting.

It was a train wreck but on an airplane. First off, flight was delayed then we board only to hear two announcements, First weather delays in Orlando and second backup battery warning on emergency lights. After sitting on the plane for almost 2 hours they have us deplane due to the maintenance issue. We were told they were getting another plane. In the mean time, I notice another American- Orlando flight and ask the gate agent if I can switch. He says he cant help me and I'd have to walk to A13 from A37. Really!? I get down there and get a seat only to get an announcement my original flight was RE-boarding. The Then inflight there's no communication and I notice on flightaware were circling over the Gulf of America. I call the flight attendant and of course she has no clue and apparently 5m later the pilot finally tells us about another delay. Why does American always have these service and delay issues? They are my LAST choice in flights now!

Mediocre would be best description. Food bland. Seat biz class uncomfortable to sleep. Crew never dimmed lights completely in an overnight flight to Europe. Would avoid AA if possible.

For my arriving destination, we were delayed multiple times to the point that we arrived 6 hours after we were originally scheduled. On my flight home, they overbooked and involuntarily removed passengers (including me) from the plane. It was not a good experience.

It was good experience this time. The flight was on time.

I very rarely fly American and my experience today reenforces that is the correct decision. While the staff were all very courteous, our flight was first thing in the morning so there was no reason to be delayed, yet appropriate maintenance checks weren’t completed prior to our flight so we were delayed multiple times. Not a great showing, American Airlines.

It's very confusing because Kayak has it as American Airlines, but it was Hawaiian Airlines, but operated by Alaska Airlines. I had to go to the airport for my boarding pass because American said I didn't have any trips.

Smooth flight. From the early boarding and all were on board before departure time and arrived early in ONT. Great crew. Thank you!!!!

Small plane, poor meal choices for first class, bad terminal and boarding experience at LAX

Everything you need to know for your flight from Denver to Panama

Information on your arrival and departure airports