$216 Find Cheap Flights from Denver to Panama

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Denver to Panama departing on 4/13. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Denver to Panama

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Panama City
Panama City1 stop$465
David
David2 stops$952
Panama City
Panama City1 stop$465
David
David2 stops$952

Book Cheap Denver to Panama Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Denver to Panama that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Denver to Panama

Sat, Apr 25 - Mon, May 4
Multiple Airlines Logo
11:05 pm - 3:54 pm
DEN
-
PTY
15h 49m
1 stop
Multiple Airlines Logo
6:15 pm - 10:30 am
PTY
-
DEN
17h 15m
1 stop
$465Multiple Airlines
Sat, Apr 25 - Tue, May 5
Multiple Airlines Logo
11:05 pm - 10:34 am
DEN
-
PTY
10h 29m
1 stop
Multiple Airlines Logo
9:33 pm - 10:30 am
PTY
-
DEN
13h 57m
1 stop
$476Multiple Airlines
Sun, Feb 22 - Mon, Mar 2
Multiple Airlines Logo
11:25 pm - 10:40 am
DEN
-
PTY
9h 15m
1 stop
Multiple Airlines Logo
9:33 pm - 9:11 am
PTY
-
DEN
13h 38m
1 stop
$478Multiple Airlines
Tue, Apr 28 - Mon, May 4
Multiple Airlines Logo
11:05 pm - 3:54 pm
DEN
-
PTY
15h 49m
1 stop
Multiple Airlines Logo
9:33 pm - 10:30 am
PTY
-
DEN
13h 57m
1 stop
$484Multiple Airlines
Tue, Feb 24 - Tue, Mar 17
Multiple Airlines Logo
11:59 pm - 4:06 pm
DEN
-
PTY
14h 07m
1 stop
Multiple Airlines Logo
9:33 pm - 8:26 am
PTY
-
DEN
11h 53m
1 stop
$489Multiple Airlines
Mon, Mar 2 - Tue, Mar 17
Multiple Airlines Logo
12:59 am - 7:20 pm
DEN
-
PTY
16h 21m
2 stops
Multiple Airlines Logo
9:33 pm - 8:26 am
PTY
-
DEN
11h 53m
1 stop
$491Multiple Airlines
Sat, Apr 11 - Sat, Apr 18
Copa Airlines Logo
10:51 pm - 5:33 am
DEN
-
PTY
5h 42mnonstop
Copa Airlines Logo
12:56 pm - 6:25 pm
PTY
-
DEN
6h 29mnonstop
$497Copa Airlines
Sun, Feb 22 - Tue, Mar 17
Multiple Airlines Logo
11:25 pm - 10:40 am
DEN
-
PTY
9h 15m
1 stop
Multiple Airlines Logo
9:33 pm - 8:26 am
PTY
-
DEN
11h 53m
1 stop
$501Multiple Airlines
Tue, May 5 - Fri, May 8
United Airlines Logo
7:45 am - 4:12 pm
DEN
-
PTY
7h 27m
1 stop
United Airlines Logo
10:00 am - 8:16 pm
PTY
-
DEN
11h 16m
1 stop
$502United Airlines
Sun, Apr 26 - Sat, May 2
American Airlines Logo
11:30 pm - 12:46 pm
DEN
-
PTY
12h 16m
1 stop
American Airlines Logo
1:49 pm - 9:38 am
PTY
-
DEN
20h 49m
2 stops
$511American Airlines
Booking Insights

KAYAK's insights & trends for Denver to Panama flights

Get data-powered insights and trends into flights from Denver to Panama to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest Denver to Panama flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to Panama from Denver found in the last 72 hours was to Panama City, at $324 round-trip. The most popular route is from Denver (DEN) to Panama City (PTY), and the cheapest round-trip airline ticket found on this route in the last 72 hours was $324.

Can I save money by flying with a layover from Denver to Panama?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $590, prices are generally cheapest when you fly direct.

What is the cheapest month to fly from Denver to Panama?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Denver to Panama, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Denver to Panama is August, when tickets cost $550 (return) on average. On the other hand, the most expensive months are December and November, when the average cost of round-trip tickets is $742 and $688 respectively.

What’s the cheapest day of the week to fly from Denver to Panama?

The average price of all round-trip flights from Denver to Panama clicked on KAYAK for each day over the last 12 months.

If you are looking for a flight deal from Denver to Panama, look for departures on Tuesdays and avoid leaving on a Saturday, as it's usually the priciest day. When flying back from Panama, Tuesday is the cheapest day to fly and Wednesday is the most expensive.

How far in advance should I book a flight from Denver to Panama?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Denver to Panama, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Denver to Panama, you should book around 7 weeks before departure, which saves you about 37% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 21 weeks before departure.

Good to know

Low seasonSeptember
Cheapest flight$192
Best time to beat the crowds with an average 18% drop in price.
Most popular time to fly with an average 19% increase in price.
Flight from Denver to Panama City

FAQs - booking Panama flights

  • How does KAYAK find such low prices on flights from Denver to Panama?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Denver to Panama.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Denver to Panama?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Denver to Panama is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Denver to Panama?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Denver to Panama with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Denver to Panama?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Denver to Panama up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to Panama?

    The cheapest time of day to fly to Panama is generally at night, when round-trip flights cost $590 on average. The most expensive time of day to fly to Panama is generally at night, which is peak travel time and where the average cost of a ticket is $590.

Reviews of the top 3 airlines serving from Denver to Panama

 
Need help choosing which airline to fly with from Denver to Panama? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.6
Copa AirlinesOverall score based on 1558 reviews
7.4Comfort
6.8Entertainment
8.1Crew
6.8Food
7.8Boarding
Airline reviews

Seats were awful. Media should have been included for such a long flight.

4.0 OkayPaul, Jan 2026
LIM - PTY
Read more Copa Airlines reviews

Seats were awful. Media should have been included for such a long flight.

There should be a warning regarding the quality of the aircraft on the website as we reserve the tickets. There was no TV or any type of screen onboard. The wifi they offer is good for nothing. Traveling 9 hours straight with kids and no type of entetainment was horrible. I wish I had been informed prior so I could buy a ticket with another airline. The food was a joke too. A very tiny portion per passenger. They also charged $100 per checked bag. With United I used to pay $60. So, fair to say that I wont be flying Copa anymore. Their aircraft was super old, outdated, no entertainment, with nearly no onboard food.

I always enjoy flying Copa. There are very few airlines where I can enjoy a comfortable sleep in-flight. The snacks weren't the best, but they sufficed. The in-flight entertainment was fantastic, and I crossed another movie off my watch list.

Very strict carry on rules meant most of the plane had to gate check their luggage. As is often the case had things that were broken because of this, but I appreciated not being charged to gate check. Otherwise good flight and great crew once on the plane

Simply as follows:- First, there was no vegetarian option for the meal Second, only 2 washrooms for the entire economy class.

I liked the meatloaf the chicken was awful but the plane was on time and got there and the staff was nice.

They were super friendly bumped me up to exit row free of charge, All flight legs were on time

Boarding was quick & efficient; they gave boarding groups due priority; staff & air crew were very cordial and helpful, pleasant flight.

Cops Airlines is fantastic! The level of care and professionalism provided by the entire crew was top rate.

the food served was an embarrassment. No connection for charging the cellphone... What a crappy airline.

Sitting on the runway after we land for almost two hours! Not sure if we should blame United or Just Dumpy Vance.

Flight was late - I was downgraded from first class to coach

United overall experience is great these days. Airport experience was very organized. Staff on flight were great. App and information as good as it gets.

Great smooth flight. Had a seating change, but that was an improvement. Thanks United Airways Crew.

Flight was good but there are way to many announcements for credit cards etc.

Crew seemed a bit cranky. No seatback screens. But boarding was efficient and on time and we arrived early.

See previous note about the passenger in Denver who threw my husband's bag out of the overhead bin in order to maker room for his own. And the flight attendant back up the new passenger.

Terrible. They wouldn't allow me on my flight on the 14th..

Impressed with the service despite turbulence because of the weather. Both flights arrived before their scheduled times.

Great experience…left a bit behind schedule but made up fir that in the air and landed 10 minutes early 😁

The screens were inoperable for movies and such, but everything else was just fine

For a 5 1/2 hour flite i considered the "business class" to be subpar. The seats were just ok, no amenities, really nothing more than a long domestic flight. Frankly disappointed.

Delayed an hour due to operational issues. Minimal apologies or care for the significant inconvenience caused. Landed at nearly 1am and they still couldn’t find ground staff to get us off the plane promptly.

This was one of the most frustrating travel experiences I've had to date. I had changed my flight day of to this one as it was slated to depart on time. It ended up being so delayed that my original flight took off before this one did. The boarding process began but eventually stopped and everyone had to get off the plane as a problem was identified. The person at the front desk just tried to laugh it off as if this wasn't already a huge inconvenience. From there, we eventually got to board only to sit at the gate for an additional hour because of some additional issue. This was extremely frustrating and caused a lot of stress.

Update to handle the delay was very bad, crews no smiles or welcome or thanks. Don’t care attitude

It would be nice to have some low carb options in the snacks.

I was trying to take 2 one and a half hour one way trips and I experienced almost 20 delays over the course of those two trips. Only a few of them were due to weather the rest was disorganization

No gates avail at DFW so our incoming had to wait 30 mins for a plane to push back because they Had mechanical. We boarded 90 mins delayed and then we had a mechanical. Come on American…do better. Also at my seat the tray table had not been cleaned. Floor had not been cleaned. But captain and flight Att were very picture and apologetic.

Crew was helpful and cheerful especially when they had no refreshments to work with. The plane was never serviced and had nothing but limited water and coffee onboard. For the price point, a concern of services.

Flight was smooth, quick and felt safe. The 2 delays not happening would have been better but I guess that happens in the airline industry

Everything you need to know for your flight from Denver to Panama

Information on your arrival and departure airports