$158 Find Cheap Flights from Denver to Panama

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Denver to Panama departing on 4/25. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Panama

Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 23% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Denver to Panama

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Panama City
Panama City1 stop$424
David
David1 stop$540
Panama City
Panama City1 stop$424
David
David1 stop$540

Book Cheap Denver to Panama Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Denver to Panama that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Denver to Panama

Mon, May 4 - Thu, May 14
Multiple Airlines Logo
11:05 pm - 7:20 pm
DEN
-
PTY
19h 15m
1 stop
Multiple Airlines Logo
3:10 pm - 8:27 am
PTY
-
DEN
18h 17m
2 stops
$424Multiple Airlines
Mon, May 4 - Tue, May 12
Multiple Airlines Logo
11:05 pm - 7:20 pm
DEN
-
PTY
19h 15m
1 stop
Multiple Airlines Logo
3:10 pm - 10:30 am
PTY
-
DEN
20h 20m
2 stops
$435Multiple Airlines
Mon, Apr 20 - Tue, Apr 28
Multiple Airlines Logo
6:15 am - 9:15 am
DEN
-
PTY
26h 00m
2 stops
Multiple Airlines Logo
3:41 pm - 9:40 am
PTY
-
DEN
18h 59m
1 stop
$442Multiple Airlines
Sun, May 3 - Mon, May 11
Multiple Airlines Logo
6:10 am - 9:15 am
DEN
-
PTY
26h 05m
2 stops
Multiple Airlines Logo
9:33 pm - 10:30 am
PTY
-
DEN
13h 57m
1 stop
$444Multiple Airlines
Tue, Apr 21 - Tue, Apr 28
Multiple Airlines Logo
11:05 pm - 8:06 am
DEN
-
PTY
32h 01m
1 stop
Multiple Airlines Logo
3:10 pm - 9:40 am
PTY
-
DEN
19h 30m
2 stops
$445Multiple Airlines
Sun, May 3 - Thu, May 14
Multiple Airlines Logo
6:10 am - 9:15 am
DEN
-
PTY
26h 05m
2 stops
Multiple Airlines Logo
9:33 pm - 8:27 am
PTY
-
DEN
11h 54m
1 stop
$447Multiple Airlines
Sat, May 2 - Thu, May 14
Multiple Airlines Logo
11:05 pm - 8:06 am
DEN
-
PTY
32h 01m
1 stop
Multiple Airlines Logo
3:10 pm - 8:27 am
PTY
-
DEN
18h 17m
2 stops
$448Multiple Airlines
Sun, Apr 19 - Tue, Apr 28
Multiple Airlines Logo
6:10 am - 9:15 am
DEN
-
PTY
26h 05m
2 stops
Multiple Airlines Logo
3:41 pm - 9:40 am
PTY
-
DEN
18h 59m
1 stop
$450Multiple Airlines
Mon, May 4 - Thu, May 14
Multiple Airlines Logo
11:05 pm - 7:20 pm
DEN
-
PTY
19h 15m
1 stop
Multiple Airlines Logo
9:33 pm - 8:27 am
PTY
-
DEN
11h 54m
1 stop
$452Multiple Airlines
Sun, Apr 19 - Mon, Apr 27
Multiple Airlines Logo
6:10 am - 9:15 am
DEN
-
PTY
26h 05m
2 stops
Multiple Airlines Logo
9:33 pm - 9:40 am
PTY
-
DEN
13h 07m
1 stop
$455Multiple Airlines
Booking Insights

KAYAK's insights & trends for Denver to Panama flights

Get data-powered insights and trends into flights from Denver to Panama to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest Denver to Panama flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to Panama from Denver found in the last 72 hours was to Panama City, at $321 round-trip. The most popular route is from Denver (DEN) to Panama City (PTY), and the cheapest round-trip airline ticket found on this route in the last 72 hours was $321.

Can I save money by flying with a layover from Denver to Panama?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 1 stop layover the cheapest option at $589 on average.

What is the cheapest month to fly from Denver to Panama?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Denver to Panama, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Denver to Panama is August, when tickets cost $535 (return) on average. On the other hand, the most expensive months are December and November, when the average cost of round-trip tickets is $739 and $688 respectively.

What’s the cheapest day of the week to fly from Denver to Panama?

The average price of all round-trip flights from Denver to Panama clicked on KAYAK for each day over the last 12 months.

If you are looking for a flight deal from Denver to Panama, look for departures on Tuesdays and avoid leaving on a Sunday, as it's usually the priciest day. When flying back from Panama, Tuesday is the cheapest day to fly and Friday is the most expensive.

How far in advance should I book a flight from Denver to Panama?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Denver to Panama, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Denver to Panama, you should book around 4 weeks before departure, which saves you about 25% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 22 weeks before departure.

Good to know

Low seasonSeptember
Cheapest flight$158
Best time to beat the crowds with an average 11% drop in price.
Most popular time to fly with an average 18% increase in price.
Flight from Denver to Panama City

FAQs - booking Panama flights

  • How does KAYAK find such low prices on flights from Denver to Panama?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Denver to Panama.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Denver to Panama?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Denver to Panama is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Denver to Panama?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Denver to Panama with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Denver to Panama?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Denver to Panama up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to Panama?

    The cheapest time of day to fly to Panama is generally at night, when round-trip flights cost $584 on average. The most expensive time of day to fly to Panama is generally at night, which is peak travel time and where the average cost of a ticket is $584.

Reviews of the top 3 airlines serving from Denver to Panama

 
Need help choosing which airline to fly with from Denver to Panama? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
Copa AirlinesOverall score based on 1565 reviews
8.1Crew
7.4Comfort
6.8Entertainment
7.8Boarding
6.8Food
Airline reviews

Seats were awful. Media should have been included for such a long flight.

4.0 OkayPaul, Jan 2026
LIM - PTY
Read more Copa Airlines reviews

Seats were awful. Media should have been included for such a long flight.

There should be a warning regarding the quality of the aircraft on the website as we reserve the tickets. There was no TV or any type of screen onboard. The wifi they offer is good for nothing. Traveling 9 hours straight with kids and no type of entetainment was horrible. I wish I had been informed prior so I could buy a ticket with another airline. The food was a joke too. A very tiny portion per passenger. They also charged $100 per checked bag. With United I used to pay $60. So, fair to say that I wont be flying Copa anymore. Their aircraft was super old, outdated, no entertainment, with nearly no onboard food.

I always enjoy flying Copa. There are very few airlines where I can enjoy a comfortable sleep in-flight. The snacks weren't the best, but they sufficed. The in-flight entertainment was fantastic, and I crossed another movie off my watch list.

Very strict carry on rules meant most of the plane had to gate check their luggage. As is often the case had things that were broken because of this, but I appreciated not being charged to gate check. Otherwise good flight and great crew once on the plane

Simply as follows:- First, there was no vegetarian option for the meal Second, only 2 washrooms for the entire economy class.

I liked the meatloaf the chicken was awful but the plane was on time and got there and the staff was nice.

They were super friendly bumped me up to exit row free of charge, All flight legs were on time

Boarding was quick & efficient; they gave boarding groups due priority; staff & air crew were very cordial and helpful, pleasant flight.

Cops Airlines is fantastic! The level of care and professionalism provided by the entire crew was top rate.

the food served was an embarrassment. No connection for charging the cellphone... What a crappy airline.

Flight left on time and we arrived 25 minutes early! There was a gate available when we arrived so early on a busy Sunday afternoon! Flight attendants came around twice with the drinks cart.

Sitting on the runway after we land for almost two hours! Not sure if we should blame United or Just Dumpy Vance.

Flight was late - I was downgraded from first class to coach

United overall experience is great these days. Airport experience was very organized. Staff on flight were great. App and information as good as it gets.

Great smooth flight. Had a seating change, but that was an improvement. Thanks United Airways Crew.

Flight was good but there are way to many announcements for credit cards etc.

Crew seemed a bit cranky. No seatback screens. But boarding was efficient and on time and we arrived early.

See previous note about the passenger in Denver who threw my husband's bag out of the overhead bin in order to maker room for his own. And the flight attendant back up the new passenger.

Terrible. They wouldn't allow me on my flight on the 14th..

Impressed with the service despite turbulence because of the weather. Both flights arrived before their scheduled times.

Other than nearly three hour delay for maintenance issues, everything went smooth

Plane from partner PSA was filthy. Plastic needs to be thoroughly cleaned. Really disgusting to look at and wonder about cleanliness of parts less visible.

The baggage claim experience was poor. The plane crew and the AA app said that checked baggage in CLT would be at carousel 7 but the sign at Baggage Claim said carousel 1. The carousel 1 sign had the correct flight # listed above the belt. But the luggage never came. I went to an AA baggage claim office after about 1 hour and the clerk directed me to another AA room that was poorly marked, with a closed door and no obvious way to know what to do. Finally someone opened the door and my bag was inside. The clerk was totally unable to explain why.

They are rarely on time! Very hard to plan your travels when flights or connections keep getting delayed.

Flight delay for mechanical. Inbound arrived on time. No one said why mechanical delay.

Forced to check bags. Crew uninterested in collecting trash. Unclean seats.

why would I bother with this airline and pick seats when I am asked to move for a weight imbalance

Flight pulled out on time but sat on runway for 30 mins. It was extremely cold in the aircraft despite wearing a winter coat. Surprisingly they had a vegetarian meal but could have some better snack choices for a 8 hour flight.

We had a male flight attendant who was super attentive and wonderful! Very professional. I have both gluten and dairy intolerance, and was only able to get a gluten free part, and not the dairy free part of the meal. Easy to order ahead of time and I appreciate being able to do that.

Snow delayed boarding several times, which I understand happens. Issue I had was that after we did board, pilot told us we were going to roll out to be de-iced, then on our way. We were de-iced once, taxied to the tarmac and then stopped. Sat for another 30 minutes or so, the another de-icing. Then we rolled out to a parking spot, only to sit for another hour due to a traffic stop in DCA, which I'm confident they knew would happen before we boarded. Pilot gave no updates other than we had to hold, attendants did speak to the crew, but when asked, said the pilot would be updating us. We on the ground in the plane waiting for over 2 hours. They did communicate that bathrooms would be open, but no other news until we left. Would have been better to be up front about status.

Everything you need to know for your flight from Denver to Panama

Information on your arrival and departure airports