$197 Find Cheap Flights from Denver to Panama

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Denver to Panama departing on 2/28. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Denver to Panama

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Panama City
Panama City2 stops$484
David
David1 stop$566
Panama City
Panama City2 stops$484
David
David1 stop$566

Book Cheap Denver to Panama Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Denver to Panama that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Denver to Panama

Thu, Feb 19 - Mon, Mar 2
Multiple Airlines Logo
7:35 pm - 8:50 am
DEN
-
PTY
35h 15m
2 stops
Multiple Airlines Logo
9:33 pm - 9:11 am
PTY
-
DEN
13h 38m
1 stop
$484Multiple Airlines
Wed, May 13 - Sat, May 23
Copa Airlines Logo
10:51 pm - 5:33 am
DEN
-
PTY
5h 42mnonstop
Copa Airlines Logo
12:56 pm - 6:25 pm
PTY
-
DEN
6h 29mnonstop
$487Copa Airlines
Mon, Apr 13 - Thu, Apr 30
Copa Airlines Logo
10:51 pm - 5:33 am
DEN
-
PTY
5h 42mnonstop
Copa Airlines Logo
12:56 pm - 6:25 pm
PTY
-
DEN
6h 29mnonstop
$497Copa Airlines
Mon, May 4 - Mon, May 11
Copa Airlines Logo
10:51 pm - 5:33 am
DEN
-
PTY
5h 42mnonstop
Copa Airlines Logo
12:56 pm - 6:25 pm
PTY
-
DEN
6h 29mnonstop
$502Copa Airlines
Thu, Apr 30 - Sat, May 16
American Airlines Logo
11:30 pm - 12:36 pm
DEN
-
PTY
12h 06m
1 stop
American Airlines Logo
1:49 pm - 11:38 am
PTY
-
DEN
22h 49m
2 stops
$506American Airlines
Tue, Apr 28 - Sun, May 3
American Airlines Logo
2:07 pm - 12:36 pm
DEN
-
PTY
21h 29m
2 stops
American Airlines Logo
1:49 pm - 1:17 pm
PTY
-
DEN
24h 28m
2 stops
$511American Airlines
Fri, Apr 10 - Sat, Apr 18
Copa Airlines Logo
10:51 pm - 5:33 am
DEN
-
PTY
5h 42mnonstop
Copa Airlines Logo
12:56 pm - 6:25 pm
PTY
-
DEN
6h 29mnonstop
$512Copa Airlines
Sat, Feb 28 - Wed, Mar 11
Multiple Airlines Logo
11:25 pm - 10:40 am
DEN
-
PTY
9h 15m
1 stop
Multiple Airlines Logo
9:45 am - 12:52 pm
PTY
-
DEN
28h 07m
2 stops
$514Multiple Airlines
Wed, Apr 1 - Tue, Apr 7
American Airlines Logo
11:31 pm - 12:40 pm
DEN
-
PTY
12h 09m
1 stop
American Airlines Logo
1:49 pm - 8:26 am
PTY
-
DEN
19h 37m
2 stops
$516American Airlines
Fri, May 1 - Sun, May 17
Copa Airlines Logo
10:51 pm - 5:33 am
DEN
-
PTY
5h 42mnonstop
Copa Airlines Logo
12:56 pm - 6:25 pm
PTY
-
DEN
6h 29mnonstop
$517Copa Airlines
Booking Insights

KAYAK's insights & trends for Denver to Panama flights

Get data-powered insights and trends into flights from Denver to Panama to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest Denver to Panama flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to Panama from Denver found in the last 72 hours was to Panama City, at $324 round-trip. The most popular route is from Denver (DEN) to Panama City (PTY), and the cheapest round-trip airline ticket found on this route in the last 72 hours was $324.

Can I save money by flying with a layover from Denver to Panama?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $589, prices are generally cheapest when you fly direct.

What is the cheapest month to fly from Denver to Panama?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Denver to Panama, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Denver to Panama is August, when tickets cost $550 (return) on average. On the other hand, the most expensive months are December and November, when the average cost of round-trip tickets is $742 and $688 respectively.

What’s the cheapest day of the week to fly from Denver to Panama?

The average price of all round-trip flights from Denver to Panama clicked on KAYAK for each day over the last 12 months.

If you are looking for a flight deal from Denver to Panama, look for departures on Tuesdays and avoid leaving on a Saturday, as it's usually the priciest day. When flying back from Panama, Tuesday is the cheapest day to fly and Wednesday is the most expensive.

How far in advance should I book a flight from Denver to Panama?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Denver to Panama, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Denver to Panama, you should book around 7 weeks before departure, which saves you about 37% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 21 weeks before departure.

Good to know

Low seasonSeptember
Cheapest flight$197
Best time to beat the crowds with an average 14% drop in price.
Most popular time to fly with an average 18% increase in price.
Flight from Denver to Panama City

FAQs - booking Panama flights

  • How does KAYAK find such low prices on flights from Denver to Panama?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Denver to Panama.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Denver to Panama?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Denver to Panama is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Denver to Panama?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Denver to Panama with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Denver to Panama?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Denver to Panama up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to Panama?

    The cheapest time of day to fly to Panama is generally at night, when round-trip flights cost $590 on average. The most expensive time of day to fly to Panama is generally at night, which is peak travel time and where the average cost of a ticket is $590.

Reviews of the top 3 airlines serving from Denver to Panama

 
Need help choosing which airline to fly with from Denver to Panama? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
Copa AirlinesOverall score based on 1560 reviews
6.8Food
6.8Entertainment
7.8Boarding
7.4Comfort
8.1Crew
Airline reviews

Seats were awful. Media should have been included for such a long flight.

4.0 OkayPaul, Jan 2026
LIM - PTY
Read more Copa Airlines reviews

Seats were awful. Media should have been included for such a long flight.

There should be a warning regarding the quality of the aircraft on the website as we reserve the tickets. There was no TV or any type of screen onboard. The wifi they offer is good for nothing. Traveling 9 hours straight with kids and no type of entetainment was horrible. I wish I had been informed prior so I could buy a ticket with another airline. The food was a joke too. A very tiny portion per passenger. They also charged $100 per checked bag. With United I used to pay $60. So, fair to say that I wont be flying Copa anymore. Their aircraft was super old, outdated, no entertainment, with nearly no onboard food.

I always enjoy flying Copa. There are very few airlines where I can enjoy a comfortable sleep in-flight. The snacks weren't the best, but they sufficed. The in-flight entertainment was fantastic, and I crossed another movie off my watch list.

Very strict carry on rules meant most of the plane had to gate check their luggage. As is often the case had things that were broken because of this, but I appreciated not being charged to gate check. Otherwise good flight and great crew once on the plane

Simply as follows:- First, there was no vegetarian option for the meal Second, only 2 washrooms for the entire economy class.

I liked the meatloaf the chicken was awful but the plane was on time and got there and the staff was nice.

They were super friendly bumped me up to exit row free of charge, All flight legs were on time

Boarding was quick & efficient; they gave boarding groups due priority; staff & air crew were very cordial and helpful, pleasant flight.

Cops Airlines is fantastic! The level of care and professionalism provided by the entire crew was top rate.

the food served was an embarrassment. No connection for charging the cellphone... What a crappy airline.

Sitting on the runway after we land for almost two hours! Not sure if we should blame United or Just Dumpy Vance.

Flight was late - I was downgraded from first class to coach

United overall experience is great these days. Airport experience was very organized. Staff on flight were great. App and information as good as it gets.

Great smooth flight. Had a seating change, but that was an improvement. Thanks United Airways Crew.

Flight was good but there are way to many announcements for credit cards etc.

Crew seemed a bit cranky. No seatback screens. But boarding was efficient and on time and we arrived early.

See previous note about the passenger in Denver who threw my husband's bag out of the overhead bin in order to maker room for his own. And the flight attendant back up the new passenger.

Terrible. They wouldn't allow me on my flight on the 14th..

Impressed with the service despite turbulence because of the weather. Both flights arrived before their scheduled times.

Great experience…left a bit behind schedule but made up fir that in the air and landed 10 minutes early 😁

No gates avail at DFW so our incoming had to wait 30 mins for a plane to push back because they Had mechanical. We boarded 90 mins delayed and then we had a mechanical. Come on American…do better. Also at my seat the tray table had not been cleaned. Floor had not been cleaned. But captain and flight Att were very picture and apologetic.

Crew was helpful and cheerful especially when they had no refreshments to work with. The plane was never serviced and had nothing but limited water and coffee onboard. For the price point, a concern of services.

Flight was smooth, quick and felt safe. The 2 delays not happening would have been better but I guess that happens in the airline industry

Flight was canceled. I asked to be rerouted to OKC and then took an Uber.

AA did not allow to board a flight because my connecting flight from DFW had been canceled. I got on another flight to another city. No service on the plane and I did not use their entertainment system.

On time on a day with lots of weather cancellations on other flights. Thank you for getting me home during a winter storm!

Don't change gate multiple times make people run across the airport. Announce delays in a timely manner. Have maintenance crew ready. Don't delay and keep passengers on the plane for 3 hrs. on tarmac.

The plane was experiencing problems with the HVAC system, it was very cold in the front of the plane and very hot in the back.

My flight to London from Philadelphia was cancelled due to weather.

The attendants were kind and helpful. A sugar-free drink would have been very welcome.

Everything you need to know for your flight from Denver to Panama

Information on your arrival and departure airports