DSM - PRG

$330 Find Cheap Flights from Des Moines to Prague - Compare and Save

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1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$731
Typical prices: $861-$1,078
United Airlines
Thu 4/19Sat 4/21
DSM - PRG • 2 stops
Cheapest one-way
$330
Typical prices: $425-$860
British Airways
Wed 1/31
DSM - PRG • 2 stops
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Flight Deals

Cheap Flights from Des Moines to Prague (DSM-PRG)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Prague

Mon, Apr 19 - Wed, Apr 21
United Airlines Logo
1:05 pm - 1:55 pmDSM  Des Moines-PRG Václav Havel Prague
17h 50m2 stops Chicago O'Hare Intl Zurich
United Airlines Logo
6:00 am - 7:25 pmPRG  Václav Havel Prague-DSM Des Moines
20h 25m2 stops Frankfurt am Main Chicago O'Hare Intl
$731United Airlines
Mon, Apr 19 - Wed, Apr 21
United Airlines Logo
1:05 pm - 1:55 pmDSM  Des Moines-PRG Václav Havel Prague
17h 50m2 stops Chicago O'Hare Intl Zurich
United Airlines Logo
6:00 am - 7:25 pmPRG  Václav Havel Prague-DSM Des Moines
20h 25m2 stops Frankfurt am Main Chicago O'Hare Intl
$741United Airlines
Wed, Dec 9 - Wed, Dec 16
United Airlines Logo
1:23 pm - 4:05 pmDSM  Des Moines-PRG Václav Havel Prague
19h 42m2 stops Denver Intl Munich Franz Josef Strauss
United Airlines Logo
7:05 am - 7:19 pmPRG  Václav Havel Prague-DSM Des Moines
19h 14m2 stops Frankfurt am Main Chicago O'Hare Intl
$819United Airlines
Tue, Nov 24 - Tue, Dec 1
Lufthansa Logo
6:45 pm - 10:40 pmDSM  Des Moines-PRG Václav Havel Prague
20h 55m2 stops Chicago O'Hare Intl Munich Franz Josef Strauss
Lufthansa Logo
7:05 am - 9:25 pmPRG  Václav Havel Prague-DSM Des Moines
21h 20m2 stops Frankfurt am Main Chicago O'Hare Intl
$901Lufthansa
Tue, Nov 24 - Tue, Dec 1
Air Canada Logo
9:50 am - 9:40 amDSM  Des Moines-PRG Václav Havel Prague
16h 50m3 stops Chicago O'Hare Intl Toronto Pearson Intl Frankfurt am Main
Air Canada Logo
10:20 am - 9:25 pmPRG  Václav Havel Prague-DSM Des Moines
18h 05m3 stops Frankfurt am Main Toronto Pearson Intl Chicago O'Hare Intl
$941Air Canada
Fri, Dec 11 - Fri, Dec 18
Delta Logo
5:29 pm - 5:05 pmDSM  Des Moines-PRG Václav Havel Prague
16h 36m2 stops Detroit Metropolitan Wayne County Paris Charles de Gaulle
Delta Logo
6:30 am - 9:31 pmPRG  Václav Havel Prague-DSM Des Moines
22h 01m2 stops Paris Charles de Gaulle Minneapolis St Paul
$953Delta
Wed, Nov 18 - Wed, Nov 25
Lufthansa Logo
6:45 pm - 10:40 pmDSM  Des Moines-PRG Václav Havel Prague
20h 55m2 stops Chicago O'Hare Intl Munich Franz Josef Strauss
Lufthansa Logo
10:20 am - 10:59 pmPRG  Václav Havel Prague-DSM Des Moines
19h 39m2 stops Frankfurt am Main Chicago O'Hare Intl
$1,005Lufthansa
Wed, Nov 18 - Wed, Nov 25
Multiple Airlines Logo
11:36 am - 11:10 amDSM  Des Moines-PRG Václav Havel Prague
16h 34m2 stops Atlanta Hartsfield-Jackson Paris Charles de Gaulle
Multiple Airlines Logo
8:55 am - 8:43 pmPRG  Václav Havel Prague-DSM Des Moines
18h 48m2 stops Amsterdam Schiphol Detroit Metropolitan Wayne County
$1,006Multiple Airlines
Wed, Nov 18 - Wed, Nov 25
Delta Logo
6:13 am - 11:10 amDSM  Des Moines-PRG Václav Havel Prague
21h 57m2 stops Detroit Metropolitan Wayne County Paris Charles de Gaulle
Delta Logo
6:00 am - 8:43 pmPRG  Václav Havel Prague-DSM Des Moines
21h 43m2 stops Amsterdam Schiphol Detroit Metropolitan Wayne County
$1,015Delta
Wed, Nov 18 - Wed, Nov 25
Delta Logo
6:13 am - 11:10 amDSM  Des Moines-PRG Václav Havel Prague
21h 57m2 stops Detroit Metropolitan Wayne County Paris Charles de Gaulle
Delta Logo
6:00 am - 8:43 pmPRG  Václav Havel Prague-DSM Des Moines
21h 43m2 stops Amsterdam Schiphol Detroit Metropolitan Wayne County
$1,016Delta
Booking Insights

Price, demand and travel trends for Des Moines to Prague flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from Des Moines to Prague?

Round-trip flights from Des Moines to Prague typically range from $861 to $1,078. The lowest price found in the past 5 days was $731, on United Airlines.

What's the cheapest day of the week to fly from Des Moines to Prague?

Based on deals KAYAK users found in the last 12 months, Monday is the cheapest day of the week to fly from Des Moines to Prague. It’s 49% cheaper than the average day, while Saturday is the most expensive, with prices 9% higher.

Key details for Des Moines to Prague flights

Cheapest flight

$330
One-way flight from Des Moines to Prague

When to book flights from Des Moines to Prague

Are your dates flexible? Find out the best times to travel from Des Moines to Prague based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Des Moines to Prague flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from Des Moines to Prague?

    Three cabin classes are available on flights from Des Moines to Prague:

    • Economy Class
    • Premium Economy Class
    • First Class

  • Do I need a passport to fly from Des Moines to Prague?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • How much should I expect to pay for a Des Moines to Prague flight?

    Round-trip flights from Des Moines to Prague range from $861 to $1,078, with an average of $984 over the past 12 months. Anything below $861 counts as a good deal.

  • Have flight prices from Des Moines to Prague changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $731 to $5,211. That means the highest observed fare was about 7x higher than the lowest one.

  • How are flight prices from Des Moines to Prague looking right now?

    One-way fares from Des Moines to Prague are currently lower than usual. Average one-way flight prices are about $335, which is 32% below the typical average for this route.

  • What car rental options are available at Václav Havel Prague Airport (PRG)?

    Václav Havel Prague Airport (PRG) hosts 5 major car rental companies, with daily rates averaging $31 for economy cars. Top options include:

    • NU Car
    • Rent Plus
    • Alamo
    • CarWiz
    • Budget

  • Which airports can I use when flying from Des Moines to Prague?

    Flights from Des Moines to Prague usually depart from Des Moines (DSM) and arrive at Václav Havel Prague (PRG).

  • Which airports do connecting flights from Des Moines to Prague pass through?

    Most connecting flights from Des Moines to Prague pass through Philadelphia (PHL), which handles 100% of one-stop traffic on this route.

  • Can I save money by using flexible dates for flights from Des Moines to Prague?

    Yes. Flexible dates can save you up to 53% on flights from Des Moines to Prague. Monday is the cheapest departure day at $510 round-trip on average, while Saturday is the most expensive at $1,078, a difference of $568.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • What is the time difference between Des Moines and Prague?

    Prague is 6 hours ahead of Des Moines (Central European Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.

  • What popular places can I visit in Prague?

    Some of the most popular sights in Prague are Pražský orloj, Charles Bridge and O2 Arena. These are among the most viewed places in Prague on KAYAK.

Your guide to booking Des Moines to Prague flights

Get tips on when to book, when to fly and what to know before your trip.

More options for your flight from Des Moines to Prague

Complete your trip to Prague with a hotel stay or car rental