Find Deals on Flights from Des Moines to Puerto Rico

Depart
Return
1 adult
Adults
18-64
Seniors
65+
Youths
12-17
Children
2-11
Seat Infants
under 2
Lap Infants
under 2
Students
under 26
The price shown for each flight will be the average for all passengers including any infants.
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Book cheap flights from Des Moines to Puerto Rico

(Round-trip)
Depart: Sat Jan 21 2017 Return: Fri Jan 27 2017 Trip spans 7 days
Major Airline
Major Airline
DSM
12:00a
SJU
2:33a
2h 33m
nonstop
SJU
8:00a
DSM
2:33p
6h 33m
nonstop
Depart: Mon Feb 13 2017 Return: Tue Feb 14 2017 Trip spans 2 days
American Airlines
American Airlines
DSM
8:23a
SJU
6:25p
10h 02m
2 stops
SJU
6:23a
DSM
6:22p
11h 59m
2 stops
Depart: Mon Feb 6 2017 Return: Sat Feb 11 2017 Trip spans 6 days
United
United
DSM
1:05p
SJU
10:50p
9h 45m
1 stop
SJU
1:00a
DSM
11:02a
10h 02m
1 stop
Depart: Thu Mar 30 2017 Return: Tue Apr 4 2017 Trip spans 6 days
Delta
Delta
DSM
3:11a
SJU
10:05a
6h 54m
1 stop
SJU
10:14a
DSM
7:17p
9h 03m
1 stop
Depart: Tue Feb 7 2017 Return: Tue Feb 14 2017 Trip spans 8 days
American Airlines
American Airlines
DSM
8:23a
SJU
6:25p
10h 02m
2 stops
SJU
6:23a
DSM
6:22p
11h 59m
2 stops
Depart: Fri Feb 10 2017 Return: Sat Feb 11 2017 Trip spans 2 days
United
United
DSM
1:05p
SJU
10:50p
9h 45m
1 stop
SJU
9:05p
DSM
11:02a
13h 57m
2 stops
Depart: Wed Feb 8 2017 Return: Tue Feb 14 2017 Trip spans 7 days
American Airlines
American Airlines
DSM
8:23a
SJU
6:25p
10h 02m
2 stops
SJU
9:11a
DSM
6:22p
9h 11m
2 stops
Depart: Sun Feb 12 2017 Return: Tue Feb 14 2017 Trip spans 3 days
United
United
DSM
9:45a
SJU
10:50p
13h 05m
2 stops
SJU
9:05p
DSM
10:56a
13h 51m
2 stops
Depart: Fri Mar 3 2017 Return: Tue Mar 7 2017 Trip spans 5 days
Delta
Delta
DSM
12:35p
SJU
9:22a
20h 47m
2 stops
SJU
11:59a
DSM
7:57p
7h 58m
1 stop
Depart: Sat Feb 11 2017 Return: Tue Feb 14 2017 Trip spans 4 days
American Airlines
American Airlines
DSM
4:36a
SJU
4:41p
12h 05m
2 stops
SJU
9:11a
DSM
6:22p
9h 11m
2 stops
Depart: Sat Feb 18 2017 Return: Wed Feb 22 2017 Trip spans 5 days
United
United
DSM
9:42a
SJU
10:49p
13h 07m
2 stops
SJU
9:05p
DSM
7:35a
10h 30m
2 stops
Depart: Thu Apr 6 2017 Return: Tue Apr 11 2017 Trip spans 6 days
Major Airline
Major Airline
DSM
2:00a
SJU
5:33a
3h 33m
nonstop
SJU
2:00a
DSM
7:33a
5h 33m
nonstop
Depart: Tue Feb 14 2017 Return: Fri Feb 17 2017 Trip spans 4 days
American Airlines
American Airlines
DSM
8:23a
SJU
6:25p
10h 02m
2 stops
SJU
10:57a
DSM
6:38p
7h 41m
1 stop
Depart: Sun Feb 19 2017 Return: Thu Feb 23 2017 Trip spans 5 days
United
United
DSM
1:05p
SJU
10:49p
9h 44m
1 stop
SJU
10:10a
DSM
6:08p
7h 58m
1 stop
Depart: Tue May 2 2017 Return: Tue May 9 2017 Trip spans 8 days
American Airlines
American Airlines
DSM
3:00a
SJU
5:15p
14h 15m
2 stops
SJU
5:22a
DSM
3:42p
10h 20m
1 stop
Depart: Sat Feb 4 2017 Return: Sat Feb 11 2017 Trip spans 8 days
United
United
DSM
9:45a
SJU
7:45p
10h 00m
2 stops
SJU
9:05p
DSM
11:02a
13h 57m
2 stops
Depart: Sat Feb 25 2017 Return: Wed Mar 1 2017 Trip spans 5 days
American Airlines
American Airlines
DSM
7:30a
SJU
2:58p
7h 28m
1 stop
SJU
4:55a
DSM
3:46p
10h 51m
1 stop
Depart: Sat Mar 11 2017 Return: Tue Mar 14 2017 Trip spans 3 days
Major Airline
Major Airline
DSM
1:00a
SJU
3:33a
2h 33m
2 stops
SJU
2:00a
DSM
7:33a
5h 33m
2 stops
Depart: Mon Feb 20 2017 Return: Wed Feb 22 2017 Trip spans 3 days
United
United
DSM
1:05p
SJU
10:49p
9h 44m
1 stop
SJU
9:05p
DSM
7:35a
10h 30m
2 stops
Depart: Mon Apr 3 2017 Return: Sun Apr 9 2017 Trip spans 7 days
Delta
Delta
DSM
2:00a
SJU
8:22a
6h 22m
1 stop
SJU
12:55p
DSM
1:38p
24h 43m
2 stops
* Prices are per person and are for e–tickets and include all taxes & fees in USD.

We attempt to get accurate prices, however, prices are not guaranteed.

Here's why:

We’re not the seller.
At KAYAK we don’t set the prices, so it’s not possible for us to guarantee what other companies are selling.

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Our service lets you quickly and easily compare results from hundreds of travel sites at once. In this sense, KAYAK is a search engine and we can't guarantee prices we find.

Why aren’t prices accurate 100% of the time?
Prices on airline seats, hotel rooms and car rentals can change frequently. Several people may also be trying to buy the same travel option simultaneously. As a result, you may find, on occasion, that certain prices are no longer available.

If you have more questions or if you have a bad price to report to us,
please send us an email and someone from our team will get back to you promptly.

^ The fares displayed in KAYAK ads found on other sites include all taxes and fees for economy class travel and were found by KAYAK users in the last 72 hours. Seats are limited and may not be available on all flights and days. Fares are subject to change and may not be available on all flights or dates of travel. Some carriers charge additional fees for extra checked bags. Please check the carriers' sites.
Airports
Origin

Des Moines
$378
Destination