$497 Find Cheap Flights from Greenville to Panama

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Greenville to Panama departing on 9/15. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Panama

Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 24% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Flight Deals
Booking Insights
Flight Deals

Book Cheap Greenville to Panama Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Greenville to Panama that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Greenville to Panama

Tue, Sep 15 - Thu, Oct 15
United Airlines Logo
7:00 am - 2:14 pm
GSP
-
PTY
8h 14m
1 stop
United Airlines Logo
10:00 am - 9:46 pm
PTY
-
GSP
10h 46m
1 stop
$497United Airlines
Tue, Sep 15 - Thu, Oct 15
United Airlines Logo
6:30 am - 6:37 pm
GSP
-
PTY
13h 07m
2 stops
United Airlines Logo
10:00 am - 9:46 pm
PTY
-
GSP
10h 46m
1 stop
$501United Airlines
Mon, Jul 6 - Mon, Jul 13
United Airlines Logo
7:49 pm - 4:04 am
GSP
-
PTY
9h 15m
1 stop
United Airlines Logo
10:55 pm - 10:37 am
PTY
-
GSP
10h 42m
1 stop
$517United Airlines
Tue, Aug 18 - Sat, Aug 22
United Airlines Logo
7:00 am - 2:14 pm
GSP
-
PTY
8h 14m
1 stop
United Airlines Logo
10:00 am - 9:53 pm
PTY
-
GSP
10h 53m
1 stop
$518United Airlines
Mon, Jul 6 - Mon, Jul 13
United Airlines Logo
5:41 pm - 2:14 pm
GSP
-
PTY
21h 33m
2 stops
United Airlines Logo
3:30 pm - 5:00 pm
PTY
-
GSP
24h 30m
2 stops
$520United Airlines
Mon, Aug 31 - Wed, Sep 2
United Airlines Logo
5:43 pm - 2:14 pm
GSP
-
PTY
21h 31m
2 stops
United Airlines Logo
3:30 pm - 9:43 am
PTY
-
GSP
17h 13m
2 stops
$521United Airlines
Tue, Aug 18 - Sat, Aug 22
United Airlines Logo
7:00 am - 6:37 pm
GSP
-
PTY
12h 37m
1 stop
United Airlines Logo
3:30 pm - 9:43 am
PTY
-
GSP
17h 13m
2 stops
$522United Airlines
Sat, Aug 15 - Wed, Aug 26
American Airlines Logo
6:20 pm - 2:20 pm
GSP
-
PTY
21h 00m
2 stops
American Airlines Logo
3:20 pm - 3:32 pm
PTY
-
GSP
23h 12m
2 stops
$532American Airlines
Mon, Aug 31 - Wed, Sep 2
United Airlines Logo
8:26 pm - 4:04 am
GSP
-
PTY
8h 38m
1 stop
United Airlines Logo
10:55 pm - 10:44 am
PTY
-
GSP
10h 49m
1 stop
$536United Airlines
Sat, Aug 15 - Wed, Aug 26
United Airlines Logo
8:26 pm - 4:04 am
GSP
-
PTY
8h 38m
1 stop
United Airlines Logo
10:55 pm - 10:44 am
PTY
-
GSP
10h 49m
1 stop
$538United Airlines
Booking Insights

KAYAK's insights & trends for Greenville to Panama flights

Get data-powered insights and trends into flights from Greenville to Panama to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Greenville to Panama?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Greenville to Panama were found on American Airlines ($497) and United Airlines ($501).

Find deals

Good to know

Low seasonAugust
Cheapest flight$497
Best time to beat the crowds with an average 37% drop in price.
Most popular time to fly and prices are also 18% lower on average.
Flight from Greenville to Panama City

FAQs - booking Panama flights

  • How does KAYAK find such low prices on flights from Greenville to Panama?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Greenville to Panama.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Greenville to Panama?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Greenville to Panama is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Greenville to Panama?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Greenville to Panama with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Greenville to Panama?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Greenville to Panama up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Greenville to Panama

 
Need help choosing which airline to fly with from Greenville to Panama? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8398 reviews
8.1Boarding
7.2Food
8.5Crew
7.8Entertainment
7.9Comfort
Airline reviews

The flight was smooth, the crew was great but the plane was quite old

8.0 ExcellentDimitrina, Apr 2026
BOS - DCA
Read more Delta reviews

The flight was smooth, the crew was great but the plane was quite old

Everything was great until I lost my water bottle and they can’t seem to locate it. I know I left it on the plane though.

WiFi didn’t work most of the time. The usb chargers would work only occasionally for 5 mins and wouldn’t charge after that. Had to keep trying repeatedly at each of the seats in the row.

The crew bent over backwards to thank us for flying and make us comfortable. The food service was quick and efficient. The Captain communicated and said goodbye and thank you as we departed. They really stood out!

Okay considering we had weather delays which the Pilot notified us of immediately!

Generally on time departures and arrivals, clean planes, sky miles membership provides great benefits (complimentary upgrades, etc).

Flight from Fort Wayne to Atlanta was the smallest in terms of cabin space that I've ever seen. A carry on I've used for 20 years BARELY fit in overhead compartment. I'm 5'10" and felt very cramped. Not the best experience.

I am writing to express my dissatisfaction with the poor service and unprofessional staff we encountered when traveling with an infant. Our flight was delayed, and the gate staff failed to manage the boarding process appropriately. Due to incorrect, unavailable, or missing 'pink tag' stroller and car seat check-in procedures at the gate, we were forced to board last. Furthermore, the gate staff was rude and dismissive, causing significant distress to our infant. To make matters worse, one of our checked items—an infant sleeper/lounger—was returned to us broken. Given the unsafe handling of essential equipment and unprofessional treatment, I expect a prompt resolution regarding compensation for the damaged items.

We departed and landed early which was a nice surprise. The boarding process was slow.

N Everything was perfect from boarding to assistance to baggage in Tampa

Everything you need to know for your flight from Greenville to Panama

Information on your arrival and departure airports

Greenville (GSP)