$392 Find Cheap Flights from Greenville to Panama

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Greenville to Panama departing on 12/10. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Panama

Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 23% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Flight Deals
Booking Insights
Flight Deals

Book Cheap Greenville to Panama Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Greenville to Panama that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Greenville to Panama

Wed, Dec 10 - Wed, Dec 17
American Airlines Logo
5:10 am - 3:42 pmGSP-PTY
10h 32m1 stop
American Airlines Logo
4:43 pm - 11:59 pmPTY-GSP
7h 16m1 stop
$392American Airlines
Find Deal
Wed, Dec 10 - Wed, Dec 17
American Airlines Logo
6:53 pm - 1:47 pmGSP-PTY
18h 54m2 stops
American Airlines Logo
2:50 pm - 8:36 amPTY-GSP
17h 46m2 stops
$396American Airlines
Find Deal
Thu, Nov 27 - Thu, Dec 4
United Airlines Logo
6:45 am - 7:38 pmGSP-PTY
12h 53m1 stop
United Airlines Logo
4:41 pm - 9:58 pmPTY-GSP
29h 17m1 stop
$400United Airlines
Find Deal
Fri, Nov 14 - Mon, Nov 17
United Airlines Logo
4:56 pm - 7:38 pmGSP-PTY
26h 42m1 stop
United Airlines Logo
4:41 pm - 9:59 pmPTY-GSP
29h 18m1 stop
$427United Airlines
Find Deal
Sun, Mar 15 - Sat, Mar 21
American Airlines Logo
7:55 pm - 2:20 pmGSP-PTY
19h 25m2 stops
American Airlines Logo
1:50 pm - 9:56 amPTY-GSP
19h 06m2 stops
$432American Airlines
Find Deal
Thu, Feb 12 - Fri, Feb 20
United Airlines Logo
6:50 am - 5:07 pmGSP-PTY
10h 17m1 stop
United Airlines Logo
11:35 am - 9:59 pmPTY-GSP
10h 24m1 stop
$435United Airlines
Find Deal
Wed, Nov 26 - Wed, Dec 3
Delta Logo
5:35 am - 2:12 pmGSP-PTY
8h 37m1 stop
Delta Logo
3:46 pm - 11:55 pmPTY-GSP
8h 09m1 stop
$503Delta
Find Deal
Sat, Nov 22 - Sat, Nov 29
Delta Logo
8:30 am - 7:59 pmGSP-PTY
11h 29m1 stop
Delta Logo
8:05 am - 9:54 pmPTY-GSP
13h 49m1 stop
$961Delta
Find Deal
Mon, Dec 15 - Sun, Jan 4
Multiple Airlines Logo
3:00 pm - 10:30 amGSP-PTY
19h 30m2 stops
Multiple Airlines Logo
2:55 am - 8:08 pmPTY-GSP
17h 13m3 stops
$1,071Multiple Airlines
Find Deal
Sat, Nov 22 - Fri, Nov 28
Multiple Airlines Logo
9:34 pm - 2:00 pmGSP-PTY
40h 26m3 stops
Multiple Airlines Logo
2:55 am - 4:48 pmPTY-GSP
37h 53m3 stops
$1,082Multiple Airlines
Find Deal
Booking Insights

KAYAK's insights & trends for Greenville to Panama flights

Get data-powered insights and trends into flights from Greenville to Panama to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Greenville to Panama?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Greenville to Panama, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Greenville to Panama is August, when tickets cost $371 (return) on average. On the other hand, the most expensive months are January and March, when the average cost of round-trip tickets is $616 and $603 respectively.

Good to know

Low seasonOctober
Cheapest flight$392
Best time to beat the crowds with an average 17% drop in price.
Most popular time to fly with an average 8% increase in price.
Flight from Greenville to Panama City

FAQs - booking Panama flights

  • How does KAYAK find such low prices on flights from Greenville to Panama?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Greenville to Panama.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Greenville to Panama?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Greenville to Panama is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Greenville to Panama?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Greenville to Panama with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Greenville to Panama?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Greenville to Panama up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to Panama?

    The cheapest time of day to fly to Panama is generally in the morning, when round-trip flights cost $441 on average. The most expensive time of day to fly to Panama is generally in the afternoon, which is peak travel time and where the average cost of a ticket is $677.

Reviews of the top 3 airlines serving from Greenville to Panama

 
Need help choosing which airline to fly with from Greenville to Panama? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 7975 reviews
8.5Crew
7.9Comfort
7.9Entertainment
8.2Boarding
7.3Food
Airline reviews

The boarding process needs to be refined. Sometimes the gate crew calls out the zones and then flip to showing the.zones boarding on the gate monitor display. So, unless you are huddled around the gate lanes watching the monitor, you could miss your boarding zone. Suggest the zones be announced each time a new zone is allowed to board.

8.0 ExcellentAnonymous, Oct 2025ATL - STL
Read more Delta reviews

The boarding process needs to be refined. Sometimes the gate crew calls out the zones and then flip to showing the.zones boarding on the gate monitor display. So, unless you are huddled around the gate lanes watching the monitor, you could miss your boarding zone. Suggest the zones be announced each time a new zone is allowed to board.

The boarding process needs to be refined. Sometimes the gate crew call out the boarding zone, and then flip to the monitor to show which zones are boarding. So unless everyone is gathered around to see the monitor there is usually confusion as wi which zones are boarding.

On time flight. Seat comfort could be better in the Comfort section.

My issue was with TSA agents for delta airlines. My luggage got flagged. The agent was going thru another persons first. He took 20 min to go thru hers. I asked them to bring mine closer so I could sit down . They said you can go sit it will be fine. I said I am supposed to keep my eyes on my bags at all times. The agent was meticulously unwrapping 2 gifts that the lady had and then tried to re warp it. He was trying to be kind i get it but 20 min for me to stand watching him do that was ridiculous. It was 6 am and there were a ton of travelers. Mine was flagged for some air packed tea that I bought in Turkey. My previous delta flight and 2 others before didn’t flag it. Consistency would be nice. Also on the flight the window shades were down for take off and landing - I thought that was very odd I thought they had to remain open for take off and landing.

The flight was an hour and a half late departing which was inconvenient

Delay in SLC jammed us up in Chicago. Got caught up in rush hour traffic

The crew took good care of us. The flight from ATL to SFO is a longer one, and there were multiple beverage offerings. I like the 757's that Delta uses. Good airplane that is comfortable. I do wish Delta would separate Priority boarding from the better seats. I would gladly take a smaller seat in an open row than be jammed into Comfort just to get priority boarding, just to make sure I don't have to check a bag.

The flight was great. The gate location was way to far away!!!

The flight attendant in first class was beyond rude and didn't care at all about her job. AND the gate agent was even worse than the flight attendant for rudeness. She was awful.

Gate agent rushed to fill hot jetway with crowd so it took over 12 minutes to go from gate to plane. Just like a discount airline Pooly prepared cabin and third time that claim of rough air prevented any cabin service. Friends on a Southwest flight at similar time had service.

The entertainment available didn’t work for anyone on the flight. Long 6 hr flight with no entertainment option and the staff didn’t know until an hour into the flight when we made sure they knew about it. They had no way to fix it.

Crew seemed a bit cranky. No seatback screens. But boarding was efficient and on time and we arrived early.

The worst landing I have ever had on a domestic flight. Thought we would lose the landing gear on landing in Newark. Then we spent 40 minutes trying to position the plane in the right place to be able to get the jet way to the plane. The plane arrived stopped. The announcer was that we were there. Everybody got up, then we were told to sit back down because they had to have us towed to a different position. We got towed and then everyone stood up and they told us we were in the wrong position to sit back down again, and then we got towed to a different position This did not happen immediately. It was 30 minutes while we wandered around a small section of the tarmac in Newark close to the gate, but apparently not close enough. Horrifying experience The CAB should be investigating that flight

Food was poorly timed and not good.. Hand held snacks, really. I kept asking for water and never got any. Service was rushed for a 7-hour flight.

Boarding was organized. Old plane. Seat fairly comfortable. Business Class much too large so you don’t receive as much attention as you should considering what you pay for the seat.

Boarding was organized. Plane seats comfortable and service was attentive. Food options were good.

This was a very average flight. The seat was out of alignment so more uncomfortable than usual. The cabin felt not well maintained. But I safely got where I needed to go.

Trip was great. A wild landing in Ottawa with the wind and rain, but the pilot did a great job. Always love flying United.👍

I will never book a flight through Cheap fare. They booked me from Portland Main . And would not give me a refund, so I bought 2 tickets one for 299. From Portland Main to ORD. Then I had to buy a ticket from Oregon PDX to ORD that was another 440. So Just so you know they even told me it was there fault but no refund. Bad bussniess. I did inform United but they said they couldn't help me due to the fact I booked through Cheap Tickets. Never again. And I'm spreding the word. I let everyone know at my 50th class reunion

We were in business class. the angled seats in that class do not have a real window view & the placement of the controls are bad. But we knew that. But the food options were mediocre. The taste was fine, but the size was for a child. It’s just really feels like United is skimping on everything. Even when we were in the Polaris lounge they did not have diet sodas. They said they were out no Coke zero no Diet Coke, etc. I do not think the portion of nuts they serve on the plane could get any smaller. Really a minimal service and offer for what you’re paying for in business.

Mostly good. Flight was crowded but Airline personnel were very friendly & accommodating. It would be good to have savory snacks rather than just sweet Biscoff cookies.

It was a typical flight. We had a delay which seems to be the normality now. And we had no in flight service due to conditions.

Flight attendants on this flight were very attentive and friendly

After we landed we sat on the tarmac for 1.5 hours waiting to get to our gate. Ridiculous.

Food should be better quality. Video screens have poor resolution and the library of movies is poor. The other airlines are much better.

the trip to madrid was uncomfortable with my legs touching the seat in front of me

The plane was late, when we did board the plane was as cold as a freezer. I was freezing the entire flight, no blankets. Lost miserable flight I’ve ever had.

My flight was delayed for 17hs because the pilot forgot his passport!!! What a joke. AA used to be a great airline, now I have to think twice before flying with them again.

Terrible. Flight delayed for more than 8 hours with only a $12 meal voucher provided for the inconvenience. The airplane did not have breaks on arrival yet they still made us go through the motions and board on time knowing we could not take off then sit for 40+ minutes before having to get of the time. A complete waste of my time. I cannot believe they can stay business with these shenanigans. I’ll avoid this company like the plague moving forward as the lack of accountability is disgraceful.

This was the best 2 flights I have had with American out of SGF. Great crew both flights.

Everything you need to know for your flight from Greenville to Panama

Information on your arrival and departure airports

Not what you’re looking for? Find thousands of other hotels, flights, car rentals and package deals with KAYAK.