GSP - PTY

$645 Find Cheap Flights from Greenville to Panama City - Compare and Save

1 adult
1 adult, Economy, 0 bags

Save 21% or more on flights. Compare deals from all over the web.

Never overpay with our price tracking tools.

Filter searches by price, airline and more to find your best flights.

Everything you should know

Cheapest round-trip
$645
Typical prices: $495-$686
American Airlines
Fri 1/5Mon 2/5
GSP - PTY • 1 stop
Nonstop flights
Not available
There are currently no direct flights between Greenville and Panama City. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to travel
February
Cheapest • 19% price drop
January
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Houston George Bush Intcntl (IAH)
Cheapest • Avg $523 (round-trip)
Atlanta Hartsfield-Jackson (ATL)
Shortest trip • 7h 33m (one-way)
Insights
Insights
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Panama City!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Greenville to Panama City (GSP-PTY)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Greenville to Panama City

Tue, Jan 5 - Fri, Feb 5
American Airlines Logo
5:30 am - 3:33 pmGSP  Greenville-PTY Panama City Tocumen Intl
10h 03m1 stop Miami
American Airlines Logo
2:26 pm - 11:59 pmPTY  Panama City Tocumen Intl-GSP Greenville
9h 33m1 stop Miami
$645American Airlines
Tue, Jan 5 - Fri, Feb 5
American Airlines Logo
5:30 am - 1:41 pmGSP  Greenville-PTY Panama City Tocumen Intl
8h 11m1 stop Miami
American Airlines Logo
4:55 pm - 11:59 pmPTY  Panama City Tocumen Intl-GSP Greenville
7h 04m1 stop Miami
$645American Airlines
Thu, Feb 18 - Mon, Mar 15
United Airlines Logo
6:00 am - 8:02 pmGSP  Greenville-PTY Panama City Tocumen Intl
14h 02m1 stop Newark
United Airlines Logo
9:30 am - 11:19 pmPTY  Panama City Tocumen Intl-GSP Greenville
12h 49m1 stop Newark
$645United Airlines
Thu, Feb 18 - Mon, Mar 15
United Airlines Logo
7:00 am - 7:38 pmGSP  Greenville-PTY Panama City Tocumen Intl
12h 38m1 stop Houston George Bush Intcntl
United Airlines Logo
9:30 am - 11:19 pmPTY  Panama City Tocumen Intl-GSP Greenville
12h 49m1 stop Newark
$645United Airlines
Tue, Jan 5 - Fri, Feb 5
American Airlines Logo
5:30 am - 1:41 pmGSP  Greenville-PTY Panama City Tocumen Intl
8h 11m1 stop Miami
American Airlines Logo
4:55 pm - 10:22 amPTY  Panama City Tocumen Intl-GSP Greenville
17h 27m2 stops Miami Philadelphia
$649American Airlines
Thu, Feb 18 - Mon, Mar 15
United Airlines Logo
6:30 am - 7:38 pmGSP  Greenville-PTY Panama City Tocumen Intl
13h 08m2 stops Chicago O'Hare Intl Houston George Bush Intcntl
United Airlines Logo
9:30 am - 11:19 pmPTY  Panama City Tocumen Intl-GSP Greenville
12h 49m1 stop Newark
$649United Airlines
Thu, Feb 18 - Mon, Mar 15
United Airlines Logo
6:30 am - 8:02 pmGSP  Greenville-PTY Panama City Tocumen Intl
13h 32m2 stops Chicago O'Hare Intl Newark
United Airlines Logo
9:30 am - 11:19 pmPTY  Panama City Tocumen Intl-GSP Greenville
12h 49m1 stop Newark
$649United Airlines
Thu, Feb 18 - Mon, Mar 15
United Airlines Logo
6:30 am - 8:02 pmGSP  Greenville-PTY Panama City Tocumen Intl
13h 32m2 stops Chicago O'Hare Intl Newark
United Airlines Logo
9:30 am - 6:50 pmPTY  Panama City Tocumen Intl-GSP Greenville
32h 20m2 stops Newark Washington, D.C. Dulles Intl
$664United Airlines
Booking Insights

Price, demand and travel trends for Greenville to Panama City flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from Greenville to Panama City?

Round-trip flights from Greenville to Panama City typically range from $495 to $686. The lowest price found in the past 5 days was $645, on American Airlines.

What's the cheapest day of the week to fly from Greenville to Panama City?

Based on deals KAYAK users found in the last 12 months, Tuesday is the cheapest day of the week to fly from Greenville to Panama City. It’s 16% cheaper than the average day, while Monday is the most expensive, with prices 133% higher.

Find deals

Key details for Greenville to Panama City flights

Low season

September

Cheapest flight

$645
Round-trip flight from Greenville to Panama City

When to book flights from Greenville to Panama City

Are your dates flexible? Find out the best times to travel from Greenville to Panama City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Greenville to Panama City flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from Greenville to Panama City?

    Only Economy Class is available on flights from Greenville to Panama City.

  • How long is a flight from Greenville to Panama City?

    A nonstop flight from Greenville to Panama City takes 00m, covering 1,792 miles.

  • Do I need a passport to fly from Greenville to Panama City?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • How much should I expect to pay for a Greenville to Panama City flight?

    Round-trip flights from Greenville to Panama City range from $495 to $686, with an average of $595 over the past 12 months. Anything below $495 counts as a good deal.

  • Have flight prices from Greenville to Panama City changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route varied from about $645 to $1,277. That means the highest observed fare was about 97% higher than the lowest one.

  • What car rental options are available at Panama City Tocumen Intl Airport (PTY)?

    Panama City Tocumen Intl Airport (PTY) hosts 5 major car rental companies, with daily rates starting from around $1 for economy cars. Top options include:

    • Avis
    • Europcar
    • Ace
    • Budget
    • Hertz

  • Which airports can I use when flying from Greenville to Panama City?

    Flights from Greenville to Panama City usually depart from Greenville (GSP) and arrive at Panama City Tocumen Intl (PTY).

  • Which airports do connecting flights from Greenville to Panama City pass through?

    One-stop flights from Greenville to Panama City most commonly connect through:

    • Houston George Bush Intcntl (IAH) - 36% of one-stop connections
    • Miami (MIA) - 24% of one-stop connections
    • Atlanta Hartsfield-Jackson (ATL) - 20% of one-stop connections
    • Newark (EWR) - 20% of one-stop connections

  • Can I save money by using flexible dates for flights from Greenville to Panama City?

    Yes. Flexible dates can save you up to 64% on flights from Greenville to Panama City. Tuesday is the cheapest departure day at $502 round-trip on average, while Monday is the most expensive at $1,387, a difference of $885.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • How much time can I save by choosing a different layover airport from Greenville to Panama City?

    Flying via Atlanta Hartsfield-Jackson (ATL) gives the shortest average 1-stop total travel time at 7h 33m, compared with 8h 11m via Miami (MIA) and 10h 01m via Houston George Bush Intcntl (IAH).

  • What is the time difference between Greenville and Panama City?

    Panama City is 1 hour behind Greenville (Eastern Time vs Eastern Time). Plan for the time shift when scheduling connections or first-day activities.

  • What popular places can I visit in Panama City?

    Some of the most popular sights in Panama City are ATLAPA Conventions Center, Panama Old Cathedral and Veneto Casino. These are among the most viewed places in Panama City on KAYAK.

Your guide to booking Greenville to Panama City flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Tuesday departure and avoid flying on Monday. On this route, Tuesday flights average $502, about $885 less than Monday fares (64% savings) based on the last 12 months.
  • If you can choose when to travel, plan your Greenville to Panama City trip for February. Fares historically average $485 round-trip in that month - typically $902 less than the most expensive month, which is December (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Panama City Tocumen Intl Airport.

    • Riande Aeropuerto Hotel & Casino

More options for your flight from Greenville to Panama City

Complete your trip to Panama City with a hotel stay or car rental

Car rentals in Panama City
Hotels in Panama City
Vacations in Panama City