GSP - PTY

$180 Find Cheap Flights from Greenville to Panama City

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Greenville to Panama City departing on 2/24. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Panama City

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Greenville to Panama City, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Greenville to Panama City, as well as popular online travel agencies
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41,299,237 searches in the past 7 days on KAYAK

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Filter your dealsChoose cabin class, free Wi-Fi and more.

Everything you should know

Cheapest round-trip
$417
Overall average: $439
American Airlines
Wed 4/1Wed 4/8
GSP - PTY • 2 stops
Cheapest one-way
$180
Delta
Tue 2/24
GSP - PTY • 1 stop
Top airlines
American Airlines
Cheapest • from $417 (round-trip)
Delta
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to travel
August
Cheapest • 30% price drop
February
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Panama City!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Greenville to Panama City (GSP-PTY)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Greenville to Panama City that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Greenville to Panama City

Wed, Apr 1 - Wed, Apr 8
American Airlines Logo
8:17 pm - 3:01 pm
GSP
-
PTY
19h 44m
2 stops
American Airlines Logo
1:49 pm - 8:35 am
PTY
-
GSP
17h 46m
2 stops
$417American Airlines
Mon, Aug 10 - Wed, Aug 12
United Airlines Logo
7:49 pm - 4:04 am
GSP
-
PTY
9h 15m
1 stop
United Airlines Logo
3:20 pm - 3:18 pm
PTY
-
GSP
22h 58m
1 stop
$421United Airlines
Wed, Mar 25 - Wed, Apr 1
American Airlines Logo
7:26 pm - 12:40 pm
GSP
-
PTY
18h 14m
1 stop
American Airlines Logo
3:51 pm - 12:21 am
PTY
-
GSP
7h 30m
1 stop
$422American Airlines
Tue, Mar 31 - Thu, Apr 16
American Airlines Logo
6:40 am - 3:01 pm
GSP
-
PTY
9h 21m
1 stop
American Airlines Logo
1:49 pm - 11:59 pm
PTY
-
GSP
9h 10m
1 stop
$423American Airlines
Wed, Mar 25 - Wed, Apr 1
American Airlines Logo
7:26 pm - 12:40 pm
GSP
-
PTY
18h 14m
1 stop
American Airlines Logo
1:40 pm - 10:44 am
PTY
-
GSP
20h 04m
2 stops
$426American Airlines
Tue, Mar 31 - Thu, Apr 16
American Airlines Logo
8:05 pm - 3:01 pm
GSP
-
PTY
19h 56m
2 stops
American Airlines Logo
1:49 pm - 8:35 am
PTY
-
GSP
17h 46m
2 stops
$427American Airlines
Mon, Aug 10 - Wed, Aug 12
United Airlines Logo
7:49 pm - 4:04 am
GSP
-
PTY
9h 15m
1 stop
United Airlines Logo
3:20 pm - 3:18 pm
PTY
-
GSP
22h 58m
1 stop
$431United Airlines
Mon, Aug 10 - Wed, Aug 12
American Airlines Logo
7:16 pm - 2:20 pm
GSP
-
PTY
20h 04m
2 stops
American Airlines Logo
3:20 pm - 6:14 pm
PTY
-
GSP
25h 54m
1 stop
$436American Airlines
Tue, Feb 24 - Tue, Mar 24
United Airlines Logo
6:50 am - 7:38 pm
GSP
-
PTY
12h 48m
1 stop
United Airlines Logo
3:41 pm - 9:58 pm
PTY
-
GSP
29h 17m
1 stop
$437United Airlines
Mon, Aug 10 - Wed, Aug 12
American Airlines Logo
6:44 pm - 2:20 pm
GSP
-
PTY
20h 36m
1 stop
American Airlines Logo
3:20 pm - 6:14 pm
PTY
-
GSP
25h 54m
1 stop
$441American Airlines
Booking Insights

KAYAK's insights & trends for Greenville to Panama City flights

Get data-powered insights and trends into flights from Greenville to Panama City to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Greenville to Panama City?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Greenville to Panama City, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Greenville to Panama City is August, where tickets cost $371 (return) on average. On the other hand, the most expensive months are December and January, where the average cost of round-trip tickets is $1,387 and $615 respectively.

Good to know

Low seasonSeptember
Cheapest flight$180
Best time to beat the crowds with an average 19% drop in price.
Most popular time to fly and prices are also 9% lower on average.
Flight from Greenville to Panama City

When to book flights from Greenville to Panama City

Are your dates flexible? Find out the best times to travel from Greenville to Panama City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Greenville to Panama City

  • What is the cheapest flight from Greenville to Panama City?

    In the last 3 days, the lowest price for a flight from Greenville to Panama City was $180 for a one-way ticket and $417 for a round-trip.

  • Do I need a passport to fly between Greenville and Panama City?

    Yes, you'll most likely have to show a valid passport before boarding the plane in Greenville and on arrival in Panama City.

  • Which airports will I be using when flying from Greenville to Panama City?

    On your way to Panama City, you’ll fly out from Greenville. You’ll be landing at Panama City Tocumen Intl.

  • Which aircraft models fly most regularly from Greenville to Panama City?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Greenville to Panama City?

    Star Alliance, and SkyTeam are the airline alliances operating flights between Greenville and Panama City, with Star Alliance being the most commonly used for this route.

  • Which is the best airline for flights from Greenville to Panama City, Delta or United Airlines?

    The two airlines most popular with KAYAK users for flights from Greenville to Panama City are Delta and United Airlines. With an average price for the route of $435 and an overall rating of 7.9, Delta is the most popular choice. United Airlines is also a great choice for the route, with an average price of $419 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from Greenville to Panama City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Greenville to Panama City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Greenville to Panama City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Panama City from Greenville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Greenville to Panama City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Panama City with an airline and back to Greenville with another airline. Booking your flights between Greenville and PTY can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Greenville to Panama City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Panama City from Greenville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Greenville to Panama City

 
See real verified KAYAK customer reviews for airlines flying from Greenville to Panama City. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Greenville to Panama City? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8180 reviews
8.1Boarding
7.9Comfort
7.8Entertainment
7.2Food
8.5Crew
Airline reviews

Awesome! On time flight, early arrival, and a complimentary upgrade!

10.0 ExcellentSarah, Feb 2026
SFO - LAX
Read more Delta reviews

Awesome! On time flight, early arrival, and a complimentary upgrade!

Paid for wifi that didn't work. No plug in seat to work. No entertainment.

We departed early and made up time in the air allowing us to arrive 30 minutes early. Capt was incredibly genuine and thanked every passenger for flying with Delta. Completely humble and professional!

Was forced to check in my small carry on, even though I informed the crew it has very fragile items inside

This was one of the worst flights I’ve been on in years. I upgraded to comfort and had such an uncomfortable experience. The person next to me was oversized - which I understand - however, they took up their space and mine. I could only use about 50% of my seat space to not be physically touching this person the entire flight and there was no spatial awareness. I also could not use the seat outlet because their body was obstructing it. It was very inconvenient. Their body kept touching me repeatedly during the flight and I felt very uncomfortable. To pay more for an upgraded space and then not even being able to use it was highly disappointing.

No wheel chair as requested at Atlanta arrival on first flight.

Only freetext wifi was available in flight; browsing WiFi required payment. Since the seats had no in flight entertainment, Delta should revisit this policy on this longer flight.

Only water, tea or coffee served midflight, even to comfort seating. Man next to me needed two seats and took up a portion of my seat and Delta did nothing.

The flight was great as well as the airline staff

First class and monitors weren’t working for mine & my husbands. Eventually fixed, but quite annoyed as we bought first class. Also, No foot rests.

Both of my flights arrived early and check in process was smooth

Terrible. No customer service, no food, no drinks on a 6 hour premier economy booking.

Short flight, but no drink/snack service. The flights both going and coming were delayed.

Much better than Spirit. I was please by the easy fast check in and boarding

Check-in and in-flight staff were better than average. The seat was a fair size but too hard and not enough padding. The cushion/pillow provided is poor (thin and seems to be disposable ,it provides no effective cushioning or support). Food was OK-ish but no choice of inflight snacks and no easy place to get drinks other than water (I could ask for juice by intruding into the staff area at the back of the plane) Entertainment was very good actually. Overall better than I expected from a US-based airline (sorry!) but compared to ANA or Singapore it was so-so. (I live in Japan so they are my comparative airlines)

Everything was on time Will use united again for sure

Plane outlets in my row not working to charge phone. Staff response was, well it should be. Plug into seed for volume not working well. Had to find the sweet spot for plug in or it would shut off and on.

Wifi took a while to kick in and we had a maintenance issue that took over 40 mins at the gate in Washington before pulling back

Fine not above and beyond as I had a connection that was delayed due to maintenance

The power at the seat didn't work and the seat itself was difficult to adjust - this was a business class seat. Flight attendant gave me miles to compensate. The attendant was very professional and on top of his game the entire flight.

Everything you need to know for your flight from Greenville to Panama City

Information on your arrival and departure airports