$226 Find Cheap Flights from Greenville to Central America - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Greenville to Central America departing on 9/9. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Greenville to Central America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
San Salvador
San Salvador1 stop$563
San José
San José2 stops$538
Guatemala City
Guatemala City1 stop$657
Panama City
Panama City1 stop$587
Liberia
Liberia1 stop$558
San Pedro Sula
San Pedro Sula1 stop$589
San Salvador
San Salvador1 stop$563
San José
San José2 stops$538
Guatemala City
Guatemala City1 stop$657
Panama City
Panama City1 stop$587
Liberia
Liberia1 stop$558
San Pedro Sula
San Pedro Sula1 stop$589

Book Cheap Greenville to Central America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Greenville to Central America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Greenville to Central America

Tue, Sep 29 - Wed, Oct 7
American Airlines Logo
7:00 am - 12:22 pm
GSP
-
BZE
7h 22m
1 stop
American Airlines Logo
1:43 pm - 11:58 pm
BZE
-
GSP
8h 15m
1 stop
$513American Airlines
Tue, Sep 29 - Wed, Oct 7
American Airlines Logo
6:23 pm - 12:22 pm
GSP
-
BZE
19h 59m
2 stops
American Airlines Logo
1:43 pm - 10:31 am
BZE
-
GSP
18h 48m
2 stops
$518American Airlines
Tue, Sep 29 - Wed, Oct 7
Multiple Airlines Logo
12:29 pm - 11:55 pm
GSP
-
SJO
37h 26m
2 stops
Multiple Airlines Logo
8:55 am - 7:44 pm
SJO
-
GSP
8h 49m
1 stop
$538Multiple Airlines
Tue, Sep 8 - Tue, Sep 15
Delta Logo
5:45 am - 12:00 pm
GSP
-
LIR
8h 15m
1 stop
Delta Logo
1:25 pm - 10:55 pm
LIR
-
GSP
7h 30m
1 stop
$558Delta
Sat, Oct 24 - Tue, Nov 3
Multiple Airlines Logo
2:51 pm - 9:55 pm
GSP
-
SAL
9h 04m
1 stop
Multiple Airlines Logo
12:05 pm - 9:54 pm
SAL
-
GSP
8h 49m
1 stop
$563Multiple Airlines
Mon, Aug 24 - Wed, Sep 2
Southwest Logo
7:00 am - 6:40 pm
GSP
-
SJO
13h 40m
2 stops
Southwest Logo
9:00 am - 8:55 pm
SJO
-
GSP
9h 55m
2 stops
$566Southwest
Fri, Sep 25 - Fri, Oct 2
Southwest Logo
7:00 am - 6:45 pm
GSP
-
SJO
13h 45m
2 stops
Southwest Logo
1:30 pm - 10:45 am
SJO
-
GSP
19h 15m
2 stops
$578Southwest
Wed, Sep 23 - Wed, Sep 30
Delta Logo
7:00 am - 12:58 pm
GSP
-
PTY
6h 58m
1 stop
Delta Logo
2:23 pm - 10:55 pm
PTY
-
GSP
7h 32m
1 stop
$587Delta
Wed, Sep 23 - Wed, Sep 30
United Airlines Logo
6:20 am - 7:31 pm
GSP
-
PTY
14h 11m
2 stops
United Airlines Logo
3:30 pm - 1:35 pm
PTY
-
GSP
21h 05m
2 stops
$591United Airlines
Tue, Sep 15 - Thu, Oct 15
United Airlines Logo
7:00 am - 7:31 pm
GSP
-
PTY
13h 31m
1 stop
United Airlines Logo
3:30 pm - 9:58 pm
PTY
-
GSP
29h 28m
1 stop
$597United Airlines
Booking Insights

KAYAK's insights & trends for Greenville to Central America flights

Get data-powered insights and trends into flights from Greenville to Central America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Greenville to Central America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Greenville to Central America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Greenville to Central America is November, when tickets cost $547 (return) on average. On the other hand, the most expensive months are December and June, when the average cost of round-trip tickets is $864 and $850 respectively.

Good to know

Low season

October

Cheapest flight

$226
Best time to beat the crowds with an average 7% drop in price.
Most popular time to fly with an average 13% increase in price.
Flight from Greenville to San José

FAQs - booking Central America flights

  • How does KAYAK find such low prices on flights from Greenville to Central America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Greenville to Central America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Greenville to Central America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Greenville to Central America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Greenville to Central America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Greenville to Central America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Greenville to Central America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Greenville to Central America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Greenville to Central America

 
Need help choosing which airline to fly with from Greenville to Central America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
DeltaOverall score based on 8487 reviews
8.5Crew
7.8Entertainment
7.2Food
8.1Boarding
7.8Comfort
Airline reviews

My son’s suitcase was left behind at SFO and did not make the flight.

6.0 GoodJorge, Jul 2026
SFO - GDL
Read more Delta reviews

My son’s suitcase was left behind at SFO and did not make the flight.

Seats were not bad enough and uncomfortable good legroom in the emergency exit row we were in, but we were forbidden to hold my grandson on my lap for a little while, and the stewardess passed us saying it was against regulations which makes little or no sense when you’re 36,000 feet. The food snacks were really bad. Tasteless tasted like wallpaper, but we’re supposed to be protein bars, and the announcements were all completely incoherent because of the noise of the airplane and the lowness and crackly nature of the PA system.. this was disgraceful. No one in our party could understand a word of what the captain or the flight attendant were saying —not a word! The landing was a little hairy in a pretty stiff crosswind -we bounced before the plane stabilized on the runway

Chaotic boarding at these gates, multiple gates squeezed in at the very end of a concourse, behind a restaurant. Agents gave up on boarding by individual zones. Flight itself was uneventful, which is all we hope for any more.

This wasn't my experience with Delta. It was just the Pegasus flight. Seats were very hard. Staff was kinda rough. Not very nice. Charged me for snacks. For a 4 hour flight I would've expected more.

I had a flight cancel and had it rerouted. When the rerouted they put me at a window seat instead of an isle. It was hard sitting by the window because the couple with masks on were making out. I get motion sickness which is why I need to have the isle seat.

They ended up paying for the bag twice, but the counter wouldn't take my baggage receipt. Left it to me to resolve. Not sure how to resolve the issue.

The plane was old with small storage areas that had problems closing/latching and not enough storage for everyone, and worn, damaged seats. Service was great but feel a little unsafe on such well used planes.

I just can’t understand why are you sell to many tickets ???? We had to wait 2 hours before 13 people from our flight take money and go to next day flight!

The only real hiccups in the flight were things beyond Delta’s control - turbulence which delayed food service and a departure delay caused by some VIP plane which stopped all departures and landings for 30 minutes - and was never explained to us by the crew. Otherwise good flight. I would fly Delta again.

The plane was frigid, and leaked water from the ceiling all over me and my seat.

Wonderful flight! The crew was good, check-in was good and orderly and the flight was uneventful and good.

Gluten free snack options and meals that offer both gluten free and dairy free.

The pilot was late so we didn’t take off til almost 2 hours late.

The SFO lounge closes at 12 midnight. My flight took off at 2AM

Not a bad flight but a long delay boarding and taking off due to the pilot not arriving on time.

Even through the flight was delayed due to storms near IAH The flight was great! The crew was so hospitable and professional

United Airlines is my preferred airlines and I am thankful for Gary who also help support me on the phone to switch my flight literally last min.

The flight was on time. I generally don’t drink or eat on short flights and the seats were good and the flight attendants were friendly. That’s all I expect

The attendant were friendly. I suggest you have a medical attendant on board every flight so that in case someone is sick , he/she will help them.

The flight and boarding were easy peasy. I was traveling with my 4-year-old, so a smooth boarding experience was especially appreciated. My only piece of feedback is really about where our gate was in O'Hare. They've shoved four gates into a tiny corner of the B terminal and there isn't early enough room or seating for everyone. Not United's problem, but did dent the overall experience.

Very good I can’t complain one bit. Thank you American Airlines for making my flight enjoyable and safe!

Flight was fine, but not having WiFi was a major negative

Everything was excellent and I enjoyed myself. Thank for everything

One of our group members was struggling to walk. In Charlotte we asked for a wheelchair and she was accompanied by Desmond. I was impressed by his patience and attention. In Boston she received the same service. I didn’t get the name of the helper but she went above and beyond in assisting us. A great AA service

I was trying to take 2 one and a half hour one way trips and I experienced almost 20 delays over the course of those two trips. Only a few of them were due to weather the rest was disorganization

Would have thought that they would gas up plane before everyone got on board

The flights were terribly delayed and then cancelled which forced us booking another night at the hotel. Very poor management from American Airlines

When my flight was delayed due to weather, I was rebooked to another flight since it showed that I would miss my connection. It was a lot of work to get back onto my originally connecting flight which was also delayed. That part caused a lot of stress and frustration. The ticketing agent at the desk was not very helpful.

American switched my flight to a 5 hour layover then cancelled my whole reservation with no notice and refused refund. Won’t fly with them again.

We sat on runway for an 1 hour because they were short handed at key west airport was not fun

Everything you need to know for your flight to Central America

Information on your arrival and departure airports