$157 Find Cheap Flights from Guatemala to Panama - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Guatemala to Panama departing on 7/30. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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Cheap Flights from Guatemala to Panama

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Guatemala to Panama that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Guatemala to Panama

Fri, Sep 25 - Sat, Oct 3
Avianca Logo
9:30 am - 5:00 pm
GUA
-
PTY
6h 30m
1 stop
Avianca Logo
3:50 pm - 11:10 pm
PTY
-
GUA
8h 20m
1 stop
$319Avianca
Tue, Aug 11 - Sun, Aug 16
Avianca Logo
6:20 am - 5:00 pm
GUA
-
PTY
9h 40m
1 stop
Avianca Logo
4:25 am - 1:00 pm
PTY
-
GUA
9h 35m
1 stop
$322Avianca
Mon, Aug 10 - Wed, Aug 12
Avianca Logo
6:20 am - 2:15 pm
GUA
-
PTY
6h 55m
1 stop
Avianca Logo
5:55 pm - 1:40 am
PTY
-
GUA
8h 45m
1 stop
$323Avianca
Tue, Aug 18 - Tue, Aug 25
Avianca Logo
6:20 am - 5:00 pm
GUA
-
PTY
9h 40m
1 stop
Avianca Logo
10:10 am - 5:00 pm
PTY
-
GUA
7h 50m
1 stop
$325Avianca
Fri, Aug 21 - Sun, Aug 23
Avianca Logo
1:55 pm - 12:35 am
GUA
-
PTY
9h 40m
1 stop
Avianca Logo
10:10 am - 1:40 am
PTY
-
GUA
16h 30m
1 stop
$326Avianca
Fri, Dec 4 - Thu, Dec 10
Avianca Logo
1:55 pm - 12:40 am
GUA
-
PTY
9h 45m
1 stop
Avianca Logo
2:55 am - 1:00 pm
PTY
-
GUA
11h 05m
1 stop
$327Avianca
Fri, Sep 4 - Thu, Sep 24
Copa Airlines Logo
6:24 am - 11:10 am
GUA
-
PTY
3h 46m
1 stop
Copa Airlines Logo
6:35 pm - 9:36 pm
PTY
-
GUA
4h 01m
1 stop
$328Copa Airlines
Thu, Aug 6 - Sun, Aug 9
Avianca Logo
6:20 am - 2:15 pm
GUA
-
PTY
6h 55m
1 stop
Avianca Logo
10:10 am - 5:00 pm
PTY
-
GUA
7h 50m
1 stop
$329Avianca
Thu, Oct 15 - Sun, Oct 25
Avianca Logo
1:55 pm - 12:35 am
GUA
-
PTY
9h 40m
1 stop
Avianca Logo
2:55 am - 5:40 pm
PTY
-
GUA
15h 45m
1 stop
$330Avianca
Thu, Sep 10 - Sat, Sep 19
Avianca Logo
7:00 am - 2:55 pm
GUA
-
PTY
6h 55m
1 stop
Avianca Logo
10:10 am - 5:00 pm
PTY
-
GUA
7h 50m
1 stop
$331Avianca
Booking Insights

KAYAK's insights & trends for flights to Panama

Get data-powered insights and trends for flights to Panama to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest flight to Panama?

These are the best round-trip prices found by users searching on KAYAK in the last 5 days.

The cheapest ticket to Panama from Guatemala found in the last 5 days was to Panama City, at $228 round-trip. The most popular route is Guatemala City (GUA) to Panama City (PTY) and the cheapest round-trip airline ticket found on this route in the last 5 days was $228.

What is the cheapest month to fly from Guatemala to Panama?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for flights from Guatemala to Panama, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Guatemala to Panama is January, when tickets cost $151 (return) on average. On the other hand, the most expensive months are June and May, when the average cost of round-trip tickets is $200 and $195 respectively.

What is the cheapest time of day to fly to Panama?

The average price for all round-trip flights from Guatemala to Panama depending on the time of departure, clicked by users on KAYAK in the last 2 weeks.

The cheapest time of day to fly to Panama is generally at night, when round-trip flights cost $362 on average. Morning departures are around 5% more expensive than evening flights, on average. The most expensive time of day to fly to Panama is generally in the afternoon, which is peak travel time and where the average cost of a ticket is $1,099.

How far in advance should I book a flight from Guatemala to Panama?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights to Panama, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Guatemala to Panama, you should book around 3 weeks before departure, which saves you about 8% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 13 weeks before departure.

Which is the cheapest airport to fly into in Panama?

Prices will differ depending on the departure airport, but generally, the cheapest airport to fly to in Panama is Panama City Tocumen Intl Airport (PTY), with an average flight price of $261.

Good to know

Low season

February

Cheapest flight

$157
Best time to beat the crowds with an average 8% drop in price.
Most popular time to fly and prices are also 10% lower on average.
Flight from Guatemala City to Panama City

FAQs for booking flights from Guatemala to Panama

  • How does KAYAK find such low prices on flights from Guatemala to Panama?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Guatemala to Panama.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Guatemala to Panama?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Guatemala to Panama is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Guatemala to Panama?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Guatemala to Panama with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Guatemala to Panama?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Guatemala to Panama up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest day to fly to Panama?

    Based on KAYAK data, the cheapest day to fly to Panama is Friday where round-trip tickets can be as cheap as $387. On the other hand, the most expensive day to fly is Monday, where round-trip prices are $480 on average.

Reviews of the top airlines flying from Guatemala to Panama

 
Need help choosing which airline to fly with from Guatemala to Panama? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.6
Copa AirlinesOverall score based on 1560 reviews
6.9Food
8.1Crew
7.8Boarding
6.8Entertainment
7.4Comfort
Airline reviews

They didn’t have any headphones for the entertainment screen and their USB port didn’t accommodate a USB-C for more modern phones. The food was just ok. The staff was friendly but the seats were very uncomfortable for a full flight.

6.0 GoodAnonymous, May 2026
SCL - PTY
Read more Copa Airlines reviews

They didn’t have any headphones for the entertainment screen and their USB port didn’t accommodate a USB-C for more modern phones. The food was just ok. The staff was friendly but the seats were very uncomfortable for a full flight.

I had to run from the end of terminal one to the end of terminal two to make the connecting flight....probably a kilometer. No electric carts were available. I'm 76 and literally had to run to make the connection at the last minute. The connecting time was absolutely unrealistic. When Last Call was announced, I tried to get other Copa gate staff to call Gate 221 to let them know I was on my way, but they said no. I came within 1 minute of missing the flight.

I was flying business class, and the French fellow passengers were super noisy. It was not a comfortable flight. And the crew was not helpful.

Boarding was a mess, they call all priority members without distinction so gold, platinum, silver were all mixed together in a long line which defeats the purpose

Entire experience from check in to landing was amazing the flight crew was excellent and friendly. Seats were comfortable.

Boarding was confusing from staff telling going to preboard and than to group 1 Airplane was not cooling at the beginning

Avoid at all costs. My wife had to stay back on a connecting flight as her parents flight was delayed. 10 days later on the way back they cancelled all our flights. We had to rebook all four of us on the next days flight.

Friendly crew, good food options, food not the best and seats not as comfy but that’s typical.

The food is terrible I ask for water never got transport my mother we’re late and my sister from Lima was the worst waiting to long for wheelchair

Seats were awful. Media should have been included for such a long flight.

After boarding, there was a small issue with the aircraft which caused a delay of about 45 minutes. During boarding and while passengers were being seated, the plane was being refueled. There were also a lot of unusual noises during the flight, which was not very reassuring. In addition, there was no WiFi or entertainment available.

They should provide water to passengers who ask for it

Not even water is offered on the flight. You cannot lean back on the seats and the seats are so narrow you can’t avoid rubbing elbows with the person next to you.

why did we have to go through security mid flight

The fees for baggage were outrageous. $130 for carry on and $150 for check in for an international flight. The seats did not recline. We were not even offered water. Had we known all of this, we would not have booked Avianca at all.

I did not like anything, first time I use company and for sure it will be the last time, they charge for simple operations that any other average airline wouldn't charge.

Discomfort has become a feature in Avianca flights. That isn’t terrible on short, local flights (most of them 1-2 Hrs)… but a 7-Hr flight with no water, no coffeee, no nothing (unless you buy it) is just not right. Uncomfortable seats, almost inhuman space between chairs, in long-haul flights needs to be reviewed by airline. And unavailable entertainment system doesn’t help either. Flight was safe and on-time, which isn’t easy to achieve. But all other features aren’t features: they’re a modern way of torture. Avianca really needs to up their game, or bluntly declare: we’re an ultra low-cost airline, and fees will drop accordingly.

Flight attendants to show up on time, offer drinks and food.

The worst airline, the crew so mean and rude, everything was a nightmare, if I start to write, I'll never end

Voo longo nem mesmo água ou gelo é servido, se quiser tem que pagar. Embarque é péssimo, mau atendimento.

Everything you need to know for your flight to Panama

Cabin class types available on flights to Panama

Cabin classes available on flights to Panama. Prices are the lowest found on KAYAK over the last 7 days. Price and availability is not guaranteed.