$59 Find Cheap Flights from Harrisburg to South Carolina - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Harrisburg to South Carolina departing on 8/8. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to South Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Harrisburg to South Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Harrisburg to South Carolina, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Harrisburg to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Charleston
Charleston1 stop$275
Myrtle Beach
Myrtle Beachnonstop$102
Greenville
Greenville1 stop$289
Columbia
Columbia1 stop$289
Florence
Florence1 stop$1,030
Charlotte
Charlotte1 stop$353
Charleston
Charleston1 stop$275
Myrtle Beach
Myrtle Beachnonstop$102
Greenville
Greenville1 stop$289
Columbia
Columbia1 stop$289
Florence
Florence1 stop$1,030
Charlotte
Charlotte1 stop$353

Book Cheap Harrisburg to South Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Harrisburg to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Harrisburg to South Carolina

Sat, Aug 8 - Thu, Aug 27
Allegiant Air Logo
3:10 pm - 4:46 pm
MDT
-
MYR
1h 36mnonstop
Allegiant Air Logo
4:52 pm - 6:25 pm
MYR
-
MDT
1h 33mnonstop
$102Allegiant Air
Sat, Jul 18 - Sun, Jul 26
Allegiant Air Logo
3:10 pm - 4:45 pm
MDT
-
MYR
1h 35mnonstop
Allegiant Air Logo
6:34 pm - 8:08 pm
MYR
-
MDT
1h 34mnonstop
$121Allegiant Air
Sat, Jul 18 - Sat, Jul 25
Delta Logo
6:22 pm - 11:53 pm
MDT
-
CHS
5h 31m
1 stop
Delta Logo
6:24 pm - 11:53 pm
CHS
-
MDT
5h 29m
1 stop
$275Delta
Tue, Jun 30 - Tue, Jul 28
Delta Logo
6:04 am - 10:22 am
MDT
-
SAV
4h 18m
1 stop
Delta Logo
5:39 am - 10:56 am
SAV
-
MDT
5h 17m
1 stop
$285Delta
Wed, Jul 15 - Wed, Jul 22
American Airlines Logo
8:15 am - 12:06 pm
MDT
-
CAE
3h 51m
1 stop
American Airlines Logo
8:30 pm - 12:25 am
CAE
-
MDT
3h 55m
1 stop
$289American Airlines
Wed, Jul 15 - Wed, Jul 22
American Airlines Logo
5:00 am - 10:07 am
MDT
-
CHS
5h 07m
1 stop
American Airlines Logo
5:00 am - 9:27 am
CHS
-
MDT
4h 27m
1 stop
$292American Airlines
Thu, Sep 3 - Sun, Sep 6
Multiple Airlines Logo
7:13 pm - 8:45 am
MDT
-
CHS
13h 32m
1 stop
Multiple Airlines Logo
2:53 pm - 9:18 am
CHS
-
MDT
18h 25m
1 stop
$327Multiple Airlines
Sat, Jul 4 - Mon, Jul 6
United Airlines Logo
10:40 am - 5:05 pm
MDT
-
CAE
6h 25m
1 stop
United Airlines Logo
7:45 pm - 11:30 pm
CAE
-
MDT
3h 45m
1 stop
$332United Airlines
Thu, Jul 9 - Sun, Jul 12
Multiple Airlines Logo
5:58 pm - 2:41 pm
MDT
-
GSP
20h 43m
1 stop
Multiple Airlines Logo
8:37 am - 5:08 pm
GSP
-
MDT
8h 31m
1 stop
$332Multiple Airlines
Fri, Jul 10 - Tue, Jul 14
United Airlines Logo
6:30 am - 2:16 pm
MDT
-
SAV
7h 46m
1 stop
United Airlines Logo
7:15 pm - 11:30 pm
SAV
-
MDT
4h 15m
1 stop
$338United Airlines
Booking Insights

KAYAK's insights & trends for Harrisburg to South Carolina flights

Get data-powered insights and trends into flights from Harrisburg to South Carolina to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Harrisburg to South Carolina?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Harrisburg to South Carolina departing in July.

What is the cheapest Harrisburg to South Carolina flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to South Carolina from Harrisburg found in the last 5 days was to Myrtle Beach, at $114 round-trip. The most popular route is from Harrisburg (MDT) to Myrtle Beach (MYR), and the cheapest round-trip airline ticket found on this route in the last 5 days was $114.

Can I save money by flying with a layover from Harrisburg to South Carolina?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $175, prices are generally cheapest when you fly direct.

What is the cheapest month to fly from Harrisburg to South Carolina?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Harrisburg to South Carolina, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Harrisburg to South Carolina is July, when tickets cost $56 (return) on average. On the other hand, the most expensive months are November and March, when the average cost of round-trip tickets is $248 and $238 respectively.

Good to know

Low seasonJanuary
Cheapest flight$59
Best time to beat the crowds with an average 12% drop in price.
Most popular time to fly and prices are also 2% lower on average.
Flight from Harrisburg to Myrtle Beach

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Harrisburg to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Harrisburg to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Harrisburg to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Harrisburg to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Harrisburg to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Harrisburg to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Harrisburg to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Harrisburg to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Top tips for finding cheap flights to South Carolina

  • Looking for a cheap flight? 25% of our users found tickets from Harrisburg to the following destinations at these prices or less: Charlotte $283 one-way - $430 round-trip; Myrtle Beach $105 one-way - $145 round-trip

Reviews of the top 4 airlines serving from Harrisburg to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Harrisburg to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Harrisburg to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
DeltaOverall score based on 8413 reviews
7.2Food
8.1Boarding
8.5Crew
7.8Comfort
7.8Entertainment
Airline reviews

Horrible. Faucet in sink not working, wifi not working. Didn’t bring food or snacks

2.0 MediocreMargaret, Jun 2026
MSY - LGA
Read more Delta reviews

Horrible. Faucet in sink not working, wifi not working. Didn’t bring food or snacks

Flight was delayed before take off and at landing. Baggage took 20 minutes. Flight crew would not serve full soft drink and had to ask multiple times before receiving water.

From checking to boarding, it was a seamless experience. The service agents were so helpful. The flight crew was so pleasant.

Gate agent showed up 20 minutes before boarding and was not at all friendly. Had to take this flight due to the one on the day before being cancelled and any later options were already full with long standby lists. Despite having paid for Delta Comfort seats, Delta did not allow me (or anyone) to choose their seat. The agent assigned them for everyone just prior to boarding. Self seat selection was allowed on the original flight. Flight staff was great - very friendly.

Flight attendants were great. Cheerful, upbeat and friendly. Jet, in particular, was fantastic.

I have Precheck. Flew HPN to DEN and return this past weekend. Delta didn't attach my Precheck number to this trip. So it was waiting in general line especially in Denver. Unavailable.

Original flight was delayed, then cancelled and the gate staff did not expedite rebooking. Also, no instructions were given that a ticket number was needed before being called to facilitate rebooking. This could have been much more organized.

Be on time? When not on time a circling for over an hour offer more than 1 bag of chips to the passengers? It was a 7 hour flight by the time we got done.

Five hour delays every hour, I wish it were all at once

Flight delayed four separate times. I’m now one hour hours late to landing.

Very easy ! Use the kiosk and bag drop and right to security within 10 min

Checking bag at terminal was horrible. No agents to check us in and only 1 kiosk working. Boarding went ok. Crew onboard was very scattered rained. Missed our row while serving and then didn’t see them hardly again.

Crew was amazing, takeoff wonderful. The bathroom was disgusting from before takeoff the odor made the flight uncomfortable as you could smell the bathroom from the center of the plane where we were sitting. Smelled like raw sewage. My daughter was throwing up as we landed due to the smell and horrible turbulence as we approached Newark.

Airline tickets are not cheap. You expect reliable competent service. Thanks to canceled flights and botched transfers we arrived at our destination two days late. This is not acceptable

Horrible! Several delays and then was cancelled! I spent over 24 hours in the airport and was unable to get a hotel or food voucher.

The entertainment is a bit limited, it would be better if they added some games to play besides the movies and tv shows. But the seats are comfortable and the crew is polite

This planes staff was top tier. Everything went great and had a great flight home.

Food was great. Staff was phenomenal. Seats were a bit hard and could use a lot more entertainment options as far as movies to choose from. WiFi was good. Overall great trip.

This was an overnight flight, and in the morning they did know coffee service. How you can throw passengers in a San Francisco airport at 5:40 a.m. in the morning and not giving them Coffee is a crime.

Our flight was delayed several Times due to mechanical issues. Although I understand this may happen at times, it was very inconvenient and we had to book a hotel for an overnight stay. We were traveling with my 3-yo grandson and waiting at the airport from noon until 6:30pm with no reassurance that our next rescheduled flight would depart, we had to decide what’s best for him. A day later, I found out that I may be able to demand compensation if my flight is delayed more than 4 hours. I will hav to read the fine print next time.

Seats were very uncomfortable and being charged for snacks and water.........

Allegiant actually impressed me, original inbound flight from PBG was so late they gave us a bird inbound from Des Moines and only left 1h late and gained 40 minutes back in the air. Comfortable flight with no frills but no complaints.

Flight was delayed. Crew was good but hot coffee was not available.

Great. No choice for n/a. No food or entertainment options

No food is available without purchasing it and there is no in-flight entertainment. Both of these are OK because we got an inexpensive flight from Allegiant and, otherwise, our experience was excellent.

just had water and there was plenty of leg & seat room. But then i don't weight 220#s!!

Not totally their fault- screaming kids that had zero parent intervention.

It was cold on the flight. The crew was very pleasant. I didn't order any food. We were delayed due to Captain waiting on maintenance log. He kept us informed though. The flight itself was smooth. I would definitely fly with Allegiant again!

I had a fantastic experience with Allegiant. I had wheelchair assistance and they helped me find my luggage and brought me to my car. Even loaded my luggage. Wonderful service!! Thank you Allegiant!

Superb. Staff great. Great flight. As with other airlines, seating too tight and restrictive.

Fine. Nothing to write home about. The plane left on time, and arrived on time.

Seat comfort was poor (no lumbar or lower back support).

Flight left early and arrived 30 MINUTES early at the destination. Smooth trip.

Flight was 3 hours delayed. They gave our plan to two other routes. Need to knock that off.

The captain announced to the cabin there would be a delay because they observed a "cut" on a tire during precheck that needed to be cleared by maintenance. We were delayed during this inspection and allowed to proceed after maintenance "measured the cut and decided it was acceptable". My complaint is not about the delay or due diligence. I wish the captain had been more generic when making his announcement. I was a nervous wreck all the way to Charlotte worried that we would have a blowout when landing!

The flight was on time and the landing was very smooth. The crew and flight attendants were all very friendly and professional.

Plane was super cold. No entertainment unless you were with mileage program Getting off the plane was super slow

I appreciate that I finally got the seat I paid extra for this time. Thank you

Half of the TSA checkpoints at PHL are closed. Also, there is no standby for first class passengers. You can only standby for coach. Very dated policy and inconsistent with peers.

It would have been nice if American tried to care.

Everything you need to know for your flight from Harrisburg to South Carolina

Information on your arrival and departure airports