$90 Find Cheap Flights from Harrisburg to South Carolina - Compare and Save

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Cheap Flights from Harrisburg to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 5 days
Charleston
Charleston1 stop$305
Myrtle Beach
Myrtle Beachnonstop$198
Greenville
Greenville1 stop$319
Columbia
Columbia1 stop$409
Charlotte
Charlotte2 stops$389
Charleston
Charleston1 stop$305
Myrtle Beach
Myrtle Beachnonstop$198
Greenville
Greenville1 stop$319
Columbia
Columbia1 stop$409
Charlotte
Charlotte2 stops$389
Booking Insights

KAYAK's insights & trends for Harrisburg to South Carolina flights

Get data-powered insights and trends into flights from Harrisburg to South Carolina to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Harrisburg to South Carolina?

Flight prices are below average for this route right now.

Flights to South Carolina from Harrisburg usually cost between $451 and $573 in October.
The lowest price found in the past 5 days was $305 on American Airlines (Oct 21-Oct 24).

What is the cheapest Harrisburg to South Carolina flight route?

The cheapest ticket to South Carolina from Harrisburg found in the last 5 days was to Myrtle Beach, at $184 round-trip. The most popular route is from Harrisburg (MDT) to Myrtle Beach (MYR), and the cheapest round-trip airline ticket found on this route in the last 5 days was $184.

Can I save money by flying with a layover from Harrisburg to South Carolina?

No, with an average price for the route of $323, prices are generally cheapest when you fly direct.

What is the cheapest month to fly from Harrisburg to South Carolina?

The cheapest month for flights from Harrisburg to South Carolina is June, when tickets cost $201 (return) on average. On the other hand, the most expensive months are March and February, when the average cost of round-trip tickets is $424 and $374 respectively.

Good to know

Low season

December

Cheapest flight

$90
Best time to beat the crowds with an average 7% drop in price.
Most popular time to fly with an average 2% increase in price.
Flight from Harrisburg to Myrtle Beach

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Harrisburg to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Harrisburg to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Harrisburg to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Harrisburg to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Harrisburg to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Harrisburg to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Harrisburg to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Harrisburg to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • How many flights are there between Harrisburg and South Carolina per day?

    There is a maximum of 1 nonstop flight a day that takes off from Harrisburg and lands in South Carolina, with an average flight time of 1h 31m. The most common departure time is 4:00 pm and most flights take off in the afternoon. Each week, there are 2 flights.

Top tips for finding cheap flights to South Carolina

  • Looking for a cheap flight? 25% of our users found tickets from Harrisburg to the following destinations at these prices or less: Charlotte $312 one-way - $391 round-trip; Myrtle Beach $119 one-way - $239 round-trip

Reviews of the top 4 airlines serving from Harrisburg to South Carolina

 
Need help choosing which airline to fly with from Harrisburg to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
DeltaOverall score based on 8579 reviews
8.1Boarding
7.2Food
7.8Comfort
7.8Entertainment
8.5Crew
Airline reviews

No Internet, no backseat screen, no nothing. I bought a Delta ticket and ended up on American Airlines. How did that happen?

6.0 GoodAlexander, Jul 2026
Read more Delta reviews

No Internet, no backseat screen, no nothing. I bought a Delta ticket and ended up on American Airlines. How did that happen?

Flight was delayed before take off and at landing. Baggage took 20 minutes. Flight crew would not serve full soft drink and had to ask multiple times before receiving water.

For some reason, TSA Atlanta didn’t have my bag on the flight on time and they don’t have to provide Delta a reason for that.

The flight was way too HOT! And the plane did not have any in-flight TV entertainment.

I am still at the Airport! Delayed Delayed and Delyaed

The landing was the worst I’ve experienced with a flight.

It was last minute due to weather - considering - it was amazing! Good smiles, friendly staff and they were making sure we knew what was going on when and where.

All good on Delta's part. Passengers could be a little more courteous to each other.

The pilots were good. Disappointing when planes don't have electrical ports

No complaints - left 20 minutes later than planned but still arrived on time.

Like the fact that the boarding was expedited. But the delay and chaos around the onboarding was not appreciated.

The flight crew were very helpful. The seats were very close together. There was barely room to sit without touching the person next to you.

It was great. All the crew were professional and nice.

The flight I was supposed to be on was supposed to take off at 1:50 from State College. It was delayed over and over and over again until somehow I had to rebook on a flight that was supposed to have left State College at 8 am that morning but didn't end up taking off until almost 6 pm. Not only was this completely unacceptable, the "token from United" was a 15 dollar meal voucher that has to be used by today. I would personally like some miles added to my account for this inconvenience. I was in transit for 8 hours from the time I arrive at State College Aiport to when I got home. I was supposed to be home at 3 pm and I returned at 8 pm. Unacceptable. I have not been on an on Time united flight in nearly 5 years.

newer aircraft, ability to connect my headset via blue tooth for entertainment.

Awful. No counter attendants. No dinner offered due to delays.

Miserable. They moved my seat, but canceled the next leg of my flight. I resolved the issue at my transfer, but that resulted in lost luggage that has taken days off my schedule with no resolution. Worse, they fail to interface effectively with Lufthansa, forcing me to bounce between two equally useless help desks. The apps are unable to handle the situation, the bag dropped off the tracker, and while the call centers are polite, they do not provide written information to assist with cross-airline communication.

The only downside was my cell phone charger wouldn’t work in the charging port but everyone else’s would work in them all. My cell phone cable works fine in my hotel room in Frankfurt.

Smoothly flight, pleasant flight attendants. I wish there were better food choices.

There was a snow storm. What else can I say. I never got home.

The flights to and from Cincinnati were great at being on time for both, departures and arrivals. The planes could use some updating.

It was a dismal experience. The flight was delayed for 4 hours, and we spent hours in the plane, without air, during the summer. We were not provided with water, and the medical assistance was inadequate when it arose.

The landing the pilot was very smooth. The flight attendant was kind of rude.The boarding the plane in punta Gorda was not great made us wait out in the heat 😞

My exit seat was very comfortable Coffee was to be purchased but sodas free 😏

It was poor a four hour delay and no explanation for the delay. What’s a 35 dollars going to do. It also made me miss my car rental,

Check in on the web portal was cumbersome! After several attempts I finally got the boarding pass.

It was canceled. The flight wasn’t rescheduled, everyone had to figure out their own new arrangements. They said we would get refunded our original fare and receive an additional $150. We received links for $100 only and they expired before we could activate them.

My TSA number was missing from my ticket which shouldn’t have happened since it’s in my file. The on board flight attendant who was a male, did not want to help me put my luggage in the overhead bin and made a very rude comment and was very unpleasant. The good… the woman who fixed my ticket with the TSA number was excellent and I had extra legroom which was perfect.

No frills, value airline. This trip was exactly what I expected. The flight was on time departing and arrived ahead of schedule. The crew was very efficient at getting people on and off the plane. I think the carry-on bag charges discouraged most people from bringing one, which led to quicker de-planing. I was careful to only bring a carefully packed personal item that was under the size limit. If you keep in mind that everything costs extra with this airline (including snacks, drinks, and printing boarding passes), and go into this with the right expectations, then all will be well. For the price difference, I would fly this airline again. My flight was only 1 hr. 20 minutes though. Much longer than that and comfort might drive me to another airline. The seats are very basic and don't recline at all.

Plane had mechanic problem that was never explained. Had to bring a plane from another airport. Six hour delay. No apology for the delay. Not even an acknowledgment.

The airline company should manage their crew for the plane on better schedule so people don’t have to wait in the plane. And this flight that I had had no snacks offered, and if you would like a water, you had to come see somebody and ask for. If airline would let people know that they are no longer providing or offering any food. At least people could bring their own if they wish.

On time departure was much appreciated. However, as a frequent flyer and American Advantage member, I was as disappointed not to get an aisle seat.

Flight was cancelled due to a myriad of operational issues. You guys really suck

Very turbulent flight, no drinks, very little service, unorganized boarding, gate changed multiple times

The captain announced to the cabin there would be a delay because they observed a "cut" on a tire during precheck that needed to be cleared by maintenance. We were delayed during this inspection and allowed to proceed after maintenance "measured the cut and decided it was acceptable". My complaint is not about the delay or due diligence. I wish the captain had been more generic when making his announcement. I was a nervous wreck all the way to Charlotte worried that we would have a blowout when landing!

Poor seat in rear of aircraft Food at Admiral’s Club Terminal D at DFW inedible

Multiple gate changes and significant delay leaving DFW. Made for a late arrival

For the price of the ticket you get nothing. The plane had 1 bathroom in the back and when the flight attendant did service no one could use it. No announcement just was told to go back to my seat. Ridiculous and rude.

In-flight Wi-Fi didn’t work and the flight was 25 minutes late. The Embraer plane I was on was pretty old and the tray table was broken.

American Airlines no longer has Bischoff biscuits. This is intolerable.

More options for your flight from Harrisburg to South Carolina

Complete your trip to South Carolina with a hotel stay or car rental