$201 Find Cheap Flights from Harrisburg to South Carolina - Compare and Save

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Cheap Flights from Harrisburg to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 5 days
Charleston
Charleston1 stop$325
Myrtle Beach
Myrtle Beach1 stop$349
Greenville
Greenville1 stop$339
Columbia
Columbia1 stop$319
Charlotte
Charlotte1 stop$380
Charleston
Charleston1 stop$325
Myrtle Beach
Myrtle Beach1 stop$349
Greenville
Greenville1 stop$339
Columbia
Columbia1 stop$319
Charlotte
Charlotte1 stop$380
Booking Insights

KAYAK's insights & trends for Harrisburg to South Carolina flights

Get data-powered insights and trends into flights from Harrisburg to South Carolina to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Harrisburg to South Carolina?

Flight prices are below average for this route right now.

Flights to South Carolina from Harrisburg usually cost between $360 and $534 in November.
The lowest price found in the past 5 days was $325 on United Airlines (Nov 25-Dec 2).

What is the cheapest Harrisburg to South Carolina flight route?

The cheapest ticket to South Carolina from Harrisburg found in the last 5 days was to Myrtle Beach, at $442 round-trip. The most popular route is from Harrisburg (MDT) to Myrtle Beach (MYR), and the cheapest round-trip airline ticket found on this route in the last 5 days was $442.

Can I save money by flying with a layover from Harrisburg to South Carolina?

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 2 stops layover the cheapest option at $331 on average.

What is the cheapest month to fly from Harrisburg to South Carolina?

The cheapest month for flights from Harrisburg to South Carolina is June, when tickets cost $199 (return) on average. On the other hand, the most expensive months are February and September, when the average cost of round-trip tickets is $396 and $386 respectively.

Good to know

Low season

December

Cheapest flight

$201
Best time to beat the crowds with an average 9% drop in price.
Flight from Harrisburg to Myrtle Beach

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Harrisburg to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Harrisburg to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Harrisburg to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Harrisburg to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Harrisburg to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Harrisburg to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Harrisburg to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Harrisburg to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Top tips for finding cheap flights to South Carolina

  • Looking for a cheap flight? 25% of our users found tickets from Harrisburg to the following destinations at these prices or less: Charlotte $328 one-way - $390 round-trip

Reviews of the top 4 airlines serving from Harrisburg to South Carolina

 
Need help choosing which airline to fly with from Harrisburg to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
DeltaOverall score based on 8693 reviews
7.2Food
8.1Boarding
7.8Entertainment
7.8Comfort
8.5Crew
Airline reviews

No Internet, no backseat screen, no nothing. I bought a Delta ticket and ended up on American Airlines. How did that happen?

6.0 GoodAlexander, Jul 2026
Read more Delta reviews

No Internet, no backseat screen, no nothing. I bought a Delta ticket and ended up on American Airlines. How did that happen?

Flight was delayed before take off and at landing. Baggage took 20 minutes. Flight crew would not serve full soft drink and had to ask multiple times before receiving water.

For some reason, TSA Atlanta didn’t have my bag on the flight on time and they don’t have to provide Delta a reason for that.

The flight was way too HOT! And the plane did not have any in-flight TV entertainment.

I am still at the Airport! Delayed Delayed and Delyaed

The landing was the worst I’ve experienced with a flight.

It was last minute due to weather - considering - it was amazing! Good smiles, friendly staff and they were making sure we knew what was going on when and where.

All good on Delta's part. Passengers could be a little more courteous to each other.

The pilots were good. Disappointing when planes don't have electrical ports

No complaints - left 20 minutes later than planned but still arrived on time.

Just sat on the run way after we arrived early

Stored my cloth purse under seat in front off me as instructed. When I retrieved it, half of it was soaked, along with everything inside it. I don’t really know how that could have been prevented because the area did not look wet, but I was not happy about it.

It was easy to board, and the staff was friendly and helpful. What could have been better is that I shouldn't have to pay extra for a seat that doesn't recline.

Was on the plane sitting longer than the actual flight in air was, boarded at 5:45p and didn't take off until 6:50p flight was only about 30 minutes long. Just was poor experience will booking more with American Airlines.

Like the fact that the boarding was expedited. But the delay and chaos around the onboarding was not appreciated.

The flight crew were very helpful. The seats were very close together. There was barely room to sit without touching the person next to you.

It was great. All the crew were professional and nice.

Awful. No counter attendants. No dinner offered due to delays.

Smoothly flight, pleasant flight attendants. I wish there were better food choices.

There was a snow storm. What else can I say. I never got home.

Terrible. We needed to change return flights due to an incoming hurricane. They would not refund our return flight.

The employees at Sioux Falls airport were friendly and helpful. As a veteran/retired military Allegiant allows two checked bags, one carry on bag and a seat on the plane all at no cost. The flight crew and pilots were friendly and very competent.

The check-in and flight crew employees are excellent. The flight was good and the seats were adequate.

The flights to and from Cincinnati were great at being on time for both, departures and arrivals. The planes could use some updating.

It was a dismal experience. The flight was delayed for 4 hours, and we spent hours in the plane, without air, during the summer. We were not provided with water, and the medical assistance was inadequate when it arose.

Check in on the web portal was cumbersome! After several attempts I finally got the boarding pass.

It was canceled. The flight wasn’t rescheduled, everyone had to figure out their own new arrangements. They said we would get refunded our original fare and receive an additional $150. We received links for $100 only and they expired before we could activate them.

My TSA number was missing from my ticket which shouldn’t have happened since it’s in my file. The on board flight attendant who was a male, did not want to help me put my luggage in the overhead bin and made a very rude comment and was very unpleasant. The good… the woman who fixed my ticket with the TSA number was excellent and I had extra legroom which was perfect.

No frills, value airline. This trip was exactly what I expected. The flight was on time departing and arrived ahead of schedule. The crew was very efficient at getting people on and off the plane. I think the carry-on bag charges discouraged most people from bringing one, which led to quicker de-planing. I was careful to only bring a carefully packed personal item that was under the size limit. If you keep in mind that everything costs extra with this airline (including snacks, drinks, and printing boarding passes), and go into this with the right expectations, then all will be well. For the price difference, I would fly this airline again. My flight was only 1 hr. 20 minutes though. Much longer than that and comfort might drive me to another airline. The seats are very basic and don't recline at all.

Plane had mechanic problem that was never explained. Had to bring a plane from another airport. Six hour delay. No apology for the delay. Not even an acknowledgment.

It was a late flight; crew was invisible. Zero air flow - the tiny plane was a sauna; the left the lights on for 1/2 of the flight; there was no water. Never again.

What an amazing plane! We flew a 787 to Miami. Although the Internet was not functioning, it was a wonderful flight.

First class snacks - stewardess gave out multiples to everyone until there was almost no selection left when she got back to me last in first class cabin. Nothing left that I would eat.

Very turbulent flight, no drinks, very little service, unorganized boarding, gate changed multiple times

The captain announced to the cabin there would be a delay because they observed a "cut" on a tire during precheck that needed to be cleared by maintenance. We were delayed during this inspection and allowed to proceed after maintenance "measured the cut and decided it was acceptable". My complaint is not about the delay or due diligence. I wish the captain had been more generic when making his announcement. I was a nervous wreck all the way to Charlotte worried that we would have a blowout when landing!

Poor seat in rear of aircraft Food at Admiral’s Club Terminal D at DFW inedible

Multiple gate changes and significant delay leaving DFW. Made for a late arrival

For the price of the ticket you get nothing. The plane had 1 bathroom in the back and when the flight attendant did service no one could use it. No announcement just was told to go back to my seat. Ridiculous and rude.

In-flight Wi-Fi didn’t work and the flight was 25 minutes late. The Embraer plane I was on was pretty old and the tray table was broken.

American Airlines no longer has Bischoff biscuits. This is intolerable.

More options for your flight from Harrisburg to South Carolina

Complete your trip to South Carolina with a hotel stay or car rental