$62 Find Cheap Flights from Harrisburg to South Carolina - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Harrisburg to South Carolina departing on 10/11. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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Cheap Flights from Harrisburg to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Charleston
Charleston1 stop$277
Myrtle Beach
Myrtle Beachnonstop$102
Greenville
Greenville1 stop$299
Columbia
Columbia1 stop$299
Florence
Florence1 stop$539
Charlotte
Charlotte1 stop$359
Charleston
Charleston1 stop$277
Myrtle Beach
Myrtle Beachnonstop$102
Greenville
Greenville1 stop$299
Columbia
Columbia1 stop$299
Florence
Florence1 stop$539
Charlotte
Charlotte1 stop$359

Book Cheap Harrisburg to South Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Harrisburg to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Harrisburg to South Carolina

Sun, Oct 18 - Thu, Oct 22
Allegiant Air Logo
3:58 pm - 5:28 pm
MDT
-
MYR
1h 30mnonstop
Allegiant Air Logo
6:25 pm - 8:01 pm
MYR
-
MDT
1h 36mnonstop
$102Allegiant Air
Thu, Sep 3 - Thu, Sep 10
Allegiant Air Logo
2:28 pm - 4:02 pm
MDT
-
MYR
1h 34mnonstop
Allegiant Air Logo
5:02 pm - 6:33 pm
MYR
-
MDT
1h 31mnonstop
$125Allegiant Air
Sun, Aug 23 - Thu, Aug 27
Multiple Airlines Logo
7:15 pm - 7:50 am
MDT
-
MYR
12h 35m
1 stop
Multiple Airlines Logo
4:52 pm - 6:25 pm
MYR
-
MDT
1h 33mnonstop
$248Multiple Airlines
Mon, Aug 24 - Thu, Aug 27
Multiple Airlines Logo
10:56 am - 10:05 am
MDT
-
MYR
23h 09m
1 stop
Multiple Airlines Logo
4:52 pm - 6:25 pm
MYR
-
MDT
1h 33mnonstop
$268Multiple Airlines
Wed, Oct 21 - Sat, Oct 24
American Airlines Logo
6:15 am - 12:37 pm
MDT
-
CHS
6h 22m
1 stop
American Airlines Logo
6:00 am - 10:16 am
CHS
-
MDT
4h 16m
1 stop
$285American Airlines
Wed, Sep 16 - Sat, Sep 19
American Airlines Logo
7:15 pm - 11:46 pm
MDT
-
CHS
4h 31m
1 stop
American Airlines Logo
6:20 am - 10:17 am
CHS
-
MDT
3h 57m
1 stop
$285American Airlines
Tue, Oct 27 - Tue, Nov 3
United Airlines Logo
10:30 am - 2:28 pm
MDT
-
CHS
3h 58m
1 stop
United Airlines Logo
12:30 pm - 8:57 pm
CHS
-
MDT
8h 27m
1 stop
$285United Airlines
Tue, Oct 27 - Tue, Nov 3
United Airlines Logo
10:30 am - 2:28 pm
MDT
-
CHS
3h 58m
1 stop
United Airlines Logo
12:30 pm - 8:57 pm
CHS
-
MDT
8h 27m
1 stop
$285United Airlines
Wed, Aug 26 - Wed, Sep 2
Delta Logo
11:55 am - 5:38 pm
MDT
-
CHS
5h 43m
1 stop
Delta Logo
5:10 am - 11:49 am
CHS
-
MDT
6h 39m
1 stop
$285Delta
Sat, Sep 19 - Sat, Sep 26
Delta Logo
6:09 pm - 11:55 pm
MDT
-
SAV
5h 46m
1 stop
Delta Logo
7:00 am - 11:44 am
SAV
-
MDT
4h 44m
1 stop
$295Delta
Booking Insights

KAYAK's insights & trends for Harrisburg to South Carolina flights

Get data-powered insights and trends into flights from Harrisburg to South Carolina to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest Harrisburg to South Carolina flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to South Carolina from Harrisburg found in the last 5 days was to Myrtle Beach, at $127 round-trip. The most popular route is from Harrisburg (MDT) to Myrtle Beach (MYR), and the cheapest round-trip airline ticket found on this route in the last 5 days was $127.

Can I save money by flying with a layover from Harrisburg to South Carolina?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $245, prices are generally cheapest when you fly direct.

What is the cheapest month to fly from Harrisburg to South Carolina?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Harrisburg to South Carolina, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Harrisburg to South Carolina is June, when tickets cost $201 (return) on average. On the other hand, the most expensive months are March and December, when the average cost of round-trip tickets is $440 and $393 respectively.

Good to know

Low season

January

Cheapest flight

$62
Best time to beat the crowds with an average 13% drop in price.
Most popular time to fly and prices are also 4% lower on average.
Flight from Harrisburg to Myrtle Beach

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Harrisburg to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Harrisburg to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Harrisburg to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Harrisburg to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Harrisburg to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Harrisburg to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Harrisburg to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Harrisburg to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • How many flights are there between Harrisburg and South Carolina per day?

    There is a maximum of 1 nonstop flight a day that takes off from Harrisburg and lands in South Carolina, with an average flight time of 1h 36m. The most common departure time is 4:00 pm and most flights take off in the afternoon. Each week, there are 3 flights.

Top tips for finding cheap flights to South Carolina

  • Looking for a cheap flight? 25% of our users found tickets from Harrisburg to the following destinations at these prices or less: Charlotte $329 one-way - $398 round-trip; Myrtle Beach $127 one-way - $146 round-trip

Reviews of the top 4 airlines serving from Harrisburg to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Harrisburg to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Harrisburg to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
DeltaOverall score based on 8489 reviews
7.2Food
7.8Comfort
7.8Entertainment
8.1Boarding
8.5Crew
Airline reviews

No Internet, no backseat screen, no nothing. I bought a Delta ticket and ended up on American Airlines. How did that happen?

6.0 GoodAlexander, Jul 2026
MDT - ATL
Read more Delta reviews

No Internet, no backseat screen, no nothing. I bought a Delta ticket and ended up on American Airlines. How did that happen?

Flight was delayed before take off and at landing. Baggage took 20 minutes. Flight crew would not serve full soft drink and had to ask multiple times before receiving water.

For some reason, TSA Atlanta didn’t have my bag on the flight on time and they don’t have to provide Delta a reason for that.

The flight was way too HOT! And the plane did not have any in-flight TV entertainment.

I am still at the Airport! Delayed Delayed and Delyaed

The landing was the worst I’ve experienced with a flight.

It was last minute due to weather - considering - it was amazing! Good smiles, friendly staff and they were making sure we knew what was going on when and where.

All good on Delta's part. Passengers could be a little more courteous to each other.

The pilots were good. Disappointing when planes don't have electrical ports

No complaints - left 20 minutes later than planned but still arrived on time.

It was great. All the crew were professional and nice.

The flight I was supposed to be on was supposed to take off at 1:50 from State College. It was delayed over and over and over again until somehow I had to rebook on a flight that was supposed to have left State College at 8 am that morning but didn't end up taking off until almost 6 pm. Not only was this completely unacceptable, the "token from United" was a 15 dollar meal voucher that has to be used by today. I would personally like some miles added to my account for this inconvenience. I was in transit for 8 hours from the time I arrive at State College Aiport to when I got home. I was supposed to be home at 3 pm and I returned at 8 pm. Unacceptable. I have not been on an on Time united flight in nearly 5 years.

newer aircraft, ability to connect my headset via blue tooth for entertainment.

Awful. No counter attendants. No dinner offered due to delays.

Miserable. They moved my seat, but canceled the next leg of my flight. I resolved the issue at my transfer, but that resulted in lost luggage that has taken days off my schedule with no resolution. Worse, they fail to interface effectively with Lufthansa, forcing me to bounce between two equally useless help desks. The apps are unable to handle the situation, the bag dropped off the tracker, and while the call centers are polite, they do not provide written information to assist with cross-airline communication.

The only downside was my cell phone charger wouldn’t work in the charging port but everyone else’s would work in them all. My cell phone cable works fine in my hotel room in Frankfurt.

Flight attendant moved my bag without notifying me and was rude to me when I asked him about it. There was no reason to move it.

Smoothly flight, pleasant flight attendants. I wish there were better food choices.

A three (3) hour flight should have meal service in First Class, not just potato chips!

There was a snow storm. What else can I say. I never got home.

It was poor a four hour delay and no explanation for the delay. What’s a 35 dollars going to do. It also made me miss my car rental,

It was on time. Flight was comfortable. Staff was nice. It was the way a flight should always be.

The price was the only good thing about this flight. It was scary during takeoff when the plane tilted side to side. It made me feel very nervous as I have never had a take-off that unsmooth. There was no on-flight movie or music options and the only complimentary option was water. Other airlines offer trail mix or a caramel cookie and pop options as complimentary. This flight was a 2.5 hour flight. I understand for shorter flights not having options, but a flight 2 hours or longer should offer more complimentary options and in flight entertainment. Also the seats did not recline and for a longer flight reclining seats are a must for comfort.

A very pleasant flight but it would be greatly improved with wifi to help entertain kids

This is a no frills, get it done, efficient airline. The seat is a lawn chair. You better bring your own entertainment. If you want something other than water you need to pay for it. But they will get you to your destination quickly, on time, and then they will turn the flight around and go right back where they came from. Reliably. Couple times a week tops. If it fits into your schedule, you can’t get there cheaper or faster.

Check in on the web portal was cumbersome! After several attempts I finally got the boarding pass.

It was canceled. The flight wasn’t rescheduled, everyone had to figure out their own new arrangements. They said we would get refunded our original fare and receive an additional $150. We received links for $100 only and they expired before we could activate them.

My TSA number was missing from my ticket which shouldn’t have happened since it’s in my file. The on board flight attendant who was a male, did not want to help me put my luggage in the overhead bin and made a very rude comment and was very unpleasant. The good… the woman who fixed my ticket with the TSA number was excellent and I had extra legroom which was perfect.

No frills, value airline. This trip was exactly what I expected. The flight was on time departing and arrived ahead of schedule. The crew was very efficient at getting people on and off the plane. I think the carry-on bag charges discouraged most people from bringing one, which led to quicker de-planing. I was careful to only bring a carefully packed personal item that was under the size limit. If you keep in mind that everything costs extra with this airline (including snacks, drinks, and printing boarding passes), and go into this with the right expectations, then all will be well. For the price difference, I would fly this airline again. My flight was only 1 hr. 20 minutes though. Much longer than that and comfort might drive me to another airline. The seats are very basic and don't recline at all.

Plane had mechanic problem that was never explained. Had to bring a plane from another airport. Six hour delay. No apology for the delay. Not even an acknowledgment.

Very good, boarded and took off on time and landed early

Boarding and Delays The boarding process for my American Airlines flight from Copenhagen to Philadelphia was a bit tricky. We experienced a gate change that required a long walk to a new area of the airport. Additionally, boarding was not via a jet bridge; we had to take a shuttle bus to the plane and then carry our luggage up the stairs ourselves. Furthermore, the bag drop didn't open until about 12:20 PM, which was only three hours before our scheduled departure. This meant I couldn't drop my bag off early and had to wait outside of security in order to drop off my bag and use the kiosk. The bag drop self-service kiosks also didn't open until about 12:00 PM when an American Airlines employee unlocked them so that we could print out our boarding passes and bag tags, which further created a backlog. The flight was delayed by over an hour because we had to wait for one of the tires on the plane to be changed. Flight Attendant Professionalism On a positive note, the flight attendant was very professional when handling a passenger who was sitting in the wrong seat. Even though the passenger was persistent and reluctant to move, the flight attendant calmly ensured the assigned passenger could take their seat. Kudos to the flight attendant for keeping his calm and composure, not allowing the issue to escalate, and handling it well under pressure while a line of passengers waited in the aisle to board. In-Flight Service The in-flight service was also fast, prompt, and efficient, although service had to be suspended for the last two hours of the flight due to weather and turbulence, which was outside of the crew's control. Limited Flight Options Please note that American Airlines only operates one flight per day in and out of Copenhagen. This means there are limited options available if your flight is delayed or canceled, which is something to take into consideration when booking.

Quick flight again no one illness why there were multiple delays and changing of the gate number.

Very turbulent flight, no drinks, very little service, unorganized boarding, gate changed multiple times

The captain announced to the cabin there would be a delay because they observed a "cut" on a tire during precheck that needed to be cleared by maintenance. We were delayed during this inspection and allowed to proceed after maintenance "measured the cut and decided it was acceptable". My complaint is not about the delay or due diligence. I wish the captain had been more generic when making his announcement. I was a nervous wreck all the way to Charlotte worried that we would have a blowout when landing!

Poor seat in rear of aircraft Food at Admiral’s Club Terminal D at DFW inedible

Multiple gate changes and significant delay leaving DFW. Made for a late arrival

For the price of the ticket you get nothing. The plane had 1 bathroom in the back and when the flight attendant did service no one could use it. No announcement just was told to go back to my seat. Ridiculous and rude.

In-flight Wi-Fi didn’t work and the flight was 25 minutes late. The Embraer plane I was on was pretty old and the tray table was broken.

American Airlines no longer has Bischoff biscuits. This is intolerable.

Everything you need to know for your flight from Harrisburg to South Carolina

Information on your arrival and departure airports