$85 Find Cheap Flights from Key West to South Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Key West to South Carolina departing on 8/6. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to South Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Key West to South Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Key West to South Carolina, as well as popular online travel agencies
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Cheap Flights from Key West to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Charleston
Charleston1 stop$141
Charlotte
Charlotte1 stop$406
Charleston
Charleston1 stop$141
Charlotte
Charlotte1 stop$406

Book Cheap Key West to South Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Key West to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Key West to South Carolina

vie., ago. 15 - mar., ago. 19
Breeze Airways Logo
1:47 pm - 9:14 amEYW-CHS
19h 27m1 stop
Breeze Airways Logo
9:00 pm - 9:22 amCHS-EYW
12h 22m1 stop
$141Breeze Airways
Find Deal
vie., ago. 15 - sáb., sep. 20
Breeze Airways Logo
1:47 pm - 9:14 amEYW-CHS
19h 27m1 stop
Breeze Airways Logo
9:05 pm - 10:19 amCHS-EYW
13h 14m1 stop
$148Breeze Airways
Find Deal
jue., sep. 18 - sáb., sep. 20
American Airlines Logo
4:49 pm - 12:05 amEYW-CHS
7h 16m1 stop
American Airlines Logo
10:31 am - 6:59 pmCHS-EYW
8h 28m2 stops
$332American Airlines
Find Deal
jue., sep. 18 - sáb., sep. 20
American Airlines Logo
11:25 am - 10:11 pmEYW-CHS
10h 46m2 stops
American Airlines Logo
10:31 am - 6:59 pmCHS-EYW
8h 28m2 stops
$337American Airlines
Find Deal
mié., ago. 27 - lun., sep. 1
Delta Logo
11:52 am - 5:04 pmEYW-AGS
5h 12m1 stop
Delta Logo
5:45 am - 10:56 amAGS-EYW
5h 11m1 stop
$343Delta
Find Deal
sáb., ago. 23 - mar., ago. 26
Delta Logo
7:00 am - 1:38 pmEYW-SAV
6h 38m1 stop
Delta Logo
2:43 pm - 8:12 pmSAV-EYW
5h 29m1 stop
$367Delta
Find Deal
jue., ago. 14 - lun., ago. 18
 Logo
10:02 am - 10:25 pmEYW-CLT
12h 23m1 stop
 Logo
6:00 am - 1:07 pmCLT-EYW
7h 07m1 stop
jue., ago. 14 - lun., ago. 18
 Logo
10:02 am - 11:55 pmEYW-CLT
13h 53m2 stops
 Logo
6:00 am - 1:07 pmCLT-EYW
7h 07m1 stop
jue., ago. 14 - lun., ago. 18
United Airlines Logo
2:22 pm - 2:25 pmEYW-CHS
24h 03m3 stops
United Airlines Logo
7:40 pm - 2:25 pmCHS-EYW
18h 45m2 stops
$743United Airlines
Find Deal
sáb., ago. 16 - sáb., ago. 23
United Airlines Logo
2:08 pm - 10:44 pmEYW-CLT
8h 36m1 stop
United Airlines Logo
6:00 am - 2:14 pmCLT-EYW
8h 14m2 stops
$1,523United Airlines
Find Deal
Booking Insights

KAYAK's insights & trends for Key West to South Carolina flights

Get data-powered insights and trends into flights from Key West to South Carolina to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Key West to South Carolina?

The average price of all round-trip flights from Key West to South Carolina clicked on KAYAK for each day over the last 12 months.

Your flight ticket price will generally be cheaper if you fly to South Carolina on a Thursday and more expensive on a Friday. On your return trip to Key West, you should consider flying back on a Wednesday, and avoid Sundays for better deals.


Good to know

Low seasonJuly
Cheapest flight$85
Best time to beat the crowds with an average 17% drop in price.
Most popular time to fly with an average 10% increase in price.
Flight from Key West to Charleston

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Key West to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Key West to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Key West to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Key West to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Key West to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Key West to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Key West to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Key West to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to South Carolina?

    The cheapest time of day to fly to South Carolina is generally in the evening, when round-trip flights cost $518 on average. Morning departures are around 10% more expensive than evening flights, on average. The most expensive time of day to fly to South Carolina is generally in the morning, which is peak travel time and where the average cost of a ticket is $571.

Top tips for finding cheap flights to South Carolina

  • Looking for a cheap flight? 25% of our users found tickets from Key West to the following destinations at these prices or less: Charlotte $248 one-way - $316 round-trip

Reviews of the top airlines flying from Key West to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Key West to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Key West to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 7983 reviews
7.9Comfort
7.9Entertainment
8.2Boarding
8.5Crew
7.3Food
Airline reviews

For a 69 year old with health problems I had the worse experience, no wheelchair when I entered a lady told me to sit and wait while a gentleman told me I had to walk to the Delta station, which I did. I had a carry on and a bag, and I was traveling with my service dog, which was on his carrier and the lady charged me for my carry on luggage, beside all the waiting cause of the delay, I had to walk to get my luggage cause no wheelchair showed up, I am so disappointed. I will get in touch with the company. I got home at 3:00 am, not good for my health situation.

2.0 MediocreRosa, Jul 2025TPA - JFK
Read more Delta reviews

For a 69 year old with health problems I had the worse experience, no wheelchair when I entered a lady told me to sit and wait while a gentleman told me I had to walk to the Delta station, which I did. I had a carry on and a bag, and I was traveling with my service dog, which was on his carrier and the lady charged me for my carry on luggage, beside all the waiting cause of the delay, I had to walk to get my luggage cause no wheelchair showed up, I am so disappointed. I will get in touch with the company. I got home at 3:00 am, not good for my health situation.

Flight was an hour late, who knows why. It was OK, nothing outstanding.

Excellent check-in. Crew was good. Excellent communication from flight deck.

Amazing flight! I have never noticed the uniforms of the attendants before in twenty years of flying except today when one female had the most amazing dress on. It was beautifully designed and showed she was in charge. I never dreamed I would google who designed Delta uniforms . The ultimate compliment is when another woman admires your outfit. . I hope your designer puts it on the market

This had nothing to do with Delta… The flights were on time and flawless. The service was excellent. We purchased seats in (aisle/middle) comfort plus since this was a cross country flight. Unfortunately, the woman seated at the window was 300+ pounds and, as might be expected, covered up about a third of the middle seat also. there was absolutely nothing that Delta could have done about that… I just don’t know what the answer should be. If you purchase a seat, you should should be able to use the entire seat and not just the portion that someone else is not sitting/oozing in. Disappointing…there should be something that could be done….I'm just not sure what solution could be.

The worst part was I was NOT allowed in the lounge even though I was holding a first class ticket and have a premium American Express card. I have flown Business or First Class with many airlines. Delta is the ONLY one who does not extend this courtesy to anyone except people who hold the very expensive American Express card. As a result, I won’t fly Delta if I have any other choice.

The Dekta Rep that checked us in was great. She's very personable, pleasant, and can tell she enjoys her job.

The young man who was our flight attendant in first class was lazy and did not do his job well at all. Never offered drinks upon boarding - actually I take that back... said "are you okay with water" as if I do not want to get you anything else, only passed the snacks around once, got my drink order wrong and then never offered a second round of drinks. He was the worst I have ever seen on Delta and we fly a lot.

Flight left early and arrived early. the whole trip was excellent.

Newer plane, relatively easy boarding, not a full flight and was told that we could not be moved up because of weight and balance issues. Otherwise, a very good experience.

It was very difficult to stretch my knee out and I am very short. I also had a torn tendon in my knee which made it extra uncomfortable anyways. My husband is 6'2" and I can't imagine him flying in that plane.

It was one of my worst flight ever. First they were changing the gate for at least 4 times, changing from gate D7 to D12 to D44. Considering the size of the Miami Airport, we are talking about long distance and the train at the airport was not working. Then the flight was delayed around one hour. Then finally we boarded into the plane and when everybody was seated, there was an announcement that there is an issue with one of the tire of the plane, so we all had to get out of the plane with our belongings, to replace the tire. So we had around 2.5-hour delay

I was late from Jacksonville, FL but the limited interaction I had with the Philly crew was great.

The delays and cancellations kept me stuck in Miami for an additional 24 hours, and the whole thing seemed extremely disorganized

The flight to Tokyo AA61 took off about two hours late, but then had to turn back. By that time the crew had to be replaced. Then they kept promising to take off in an hour, then in 3, then switch to the next day.

Crew professional. Easy bag drop off. On time. Good entertainment.

Flight was late and missed connecting flight. They could have better accommodated, but instead did an overnight and had to arrive the next afternoon.

The boarding crew was incredibly helpful getting me on an earlier flight

They have lost any customer service care and support. Terrible airline now and been for awhile.

The flight was delayed leaving Miami. When we arrived in Charlotte, we were unable to park at our scheduled gate. We had to wait another 30-45 minutes before we could park at a different gate. All in all, we were delayed by almost two hours arriving in Charlotte.

Everything you need to know for your flight from Key West to South Carolina

Information on your arrival and departure airports

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