STL - STI

$228 Find Cheap Flights from St. Louis to Santiago de los Caballeros

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from St. Louis to Santiago de los Caballeros departing on 12/15. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santiago de los Caballeros

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from St. Louis to Santiago de los Caballeros, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from St. Louis to Santiago de los Caballeros, as well as popular online travel agencies
Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 23% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Flight Deals
Booking Insights
Flight Deals

Cheap Flights from St. Louis to Santiago de los Caballeros (STL-STI)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from St. Louis to Santiago de los Caballeros that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from St. Louis to Santiago de los Caballeros

Mon, Jan 12 - Fri, Jan 23
Delta Logo
10:19 am - 12:50 amSTL-STI
12h 31m2 stops
Delta Logo
6:39 am - 8:45 pmSTI-STL
16h 06m2 stops
$522Delta
Find Deal
Sat, Feb 21 - Sat, Feb 28
Delta Logo
6:45 am - 12:53 amSTL-STI
16h 08m2 stops
Delta Logo
6:35 am - 8:39 pmSTI-STL
16h 04m2 stops
$572Delta
Find Deal
Sat, Feb 21 - Sat, Feb 28
American Airlines Logo
6:16 pm - 1:32 pmSTL-STI
17h 16m1 stop
American Airlines Logo
2:34 pm - 10:27 amSTI-STL
21h 53m1 stop
$591American Airlines
Find Deal
Sat, Feb 21 - Sat, Feb 28
American Airlines Logo
6:16 pm - 1:32 pmSTL-STI
17h 16m1 stop
American Airlines Logo
2:34 pm - 8:52 amSTI-STL
20h 18m2 stops
$592American Airlines
Find Deal
Sat, Feb 21 - Sat, Feb 28
American Airlines Logo
6:16 pm - 1:32 pmSTL-STI
17h 16m1 stop
American Airlines Logo
8:00 am - 10:27 amSTI-STL
28h 27m1 stop
$602American Airlines
Find Deal
Thu, Feb 26 - Mon, Mar 2
United Airlines Logo
7:41 am - 11:51 pmSTL-STI
14h 10m2 stops
United Airlines Logo
4:00 pm - 12:05 amSTI-STL
10h 05m1 stop
$658United Airlines
Find Deal
Sat, Dec 13 - Sat, Dec 20
American Airlines Logo
5:30 pm - 3:32 pmSTL-STI
20h 02m2 stops
American Airlines Logo
3:24 pm - 10:35 pmSTI-STL
9h 11m1 stop
$667American Airlines
Find Deal
Thu, Feb 26 - Mon, Mar 2
American Airlines Logo
11:19 am - 10:04 pmSTL-STI
8h 45m1 stop
American Airlines Logo
2:34 pm - 10:05 pmSTI-STL
9h 31m1 stop
$688American Airlines
Find Deal
Thu, Feb 26 - Mon, Mar 2
American Airlines Logo
6:04 am - 10:04 pmSTL-STI
14h 00m2 stops
American Airlines Logo
8:00 am - 9:31 pmSTI-STL
15h 31m2 stops
$692American Airlines
Find Deal
Wed, Dec 17 - Tue, Dec 30
Delta Logo
4:32 pm - 12:59 pmSTL-STI
18h 27m1 stop
Delta Logo
3:30 am - 4:59 pmSTI-STL
15h 29m1 stop
$1,488Delta
Find Deal

Everything you should know

Top airlines
Delta
Cheapest • from $522 (round-trip)
American Airlines
Best reviews • 7.2 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Cheapest round-trip
$522
Delta
Mon 1/12Fri 1/23
STL - STI • 2 stops
Cheapest one-way
$228
Multiple Airlines
Mon 12/15
STL - STI • 2 stops
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Santiago de los Caballeros!
Booking Insights

KAYAK's insights & trends for St. Louis to Santiago de los Caballeros flights

Get data-powered insights and trends into flights from St. Louis to Santiago de los Caballeros to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from St. Louis to Santiago de los Caballeros?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from St. Louis to Santiago de los Caballeros were found on Delta ($522) and American Airlines ($591).

Which airlines fly non-stop between St. Louis and Santiago de los Caballeros?

Airline and price data is aggregated from results in KAYAK’s search results from the last 2 weeks for round-trip flights from St. Louis to Santiago de los Caballeros.

There is just one airline that flies from St. Louis to Santiago de los Caballeros direct and that is American Airlines. The best round-trip deal found from American Airlines for the route is $604.

Find deals

Good to know

Low seasonApril
Cheapest flight$228
Best time to beat the crowds with an average 21% drop in price.
Most popular time to fly with an average 25% increase in price.
Flight from St. Louis to Santiago de los Caballeros

When to book flights from St. Louis to Santiago de los Caballeros

Are your dates flexible? Find out the best times to travel from St. Louis to Santiago de los Caballeros based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from St. Louis to Santiago de los Caballeros

  • What is the cheapest flight from St. Louis to Santiago de los Caballeros?

    In the last 3 days, the lowest price for a flight from St. Louis to Santiago de los Caballeros was $228 for a one-way ticket and $522 for a round-trip.

  • Do I need a passport to fly between St. Louis and Santiago de los Caballeros?

    Yes, you'll most likely have to show a valid passport before boarding the plane in St. Louis and on arrival in Santiago de los Caballeros.

  • Which aircraft models fly most regularly from St. Louis to Santiago de los Caballeros?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from St. Louis to Santiago de los Caballeros?

    oneworld is the only airline alliance operating flights between St. Louis and Santiago de los Caballeros.

  • How does KAYAK find such low prices on flights from St. Louis to Santiago de los Caballeros?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from St. Louis to Santiago de los Caballeros.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from St. Louis to Santiago de los Caballeros?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santiago de los Caballeros from St. Louis is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from St. Louis to Santiago de los Caballeros?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santiago de los Caballeros with an airline and back to St. Louis with another airline. Booking your flights between St. Louis and STI can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from St. Louis to Santiago de los Caballeros?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santiago de los Caballeros from St. Louis up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from St. Louis to Santiago de los Caballeros

 
See real verified KAYAK customer reviews for airlines flying from St. Louis to Santiago de los Caballeros. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from St. Louis to Santiago de los Caballeros? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 11030 reviews
7.5Boarding
6.9Entertainment
8.0Crew
7.2Comfort
6.4Food
Airline reviews

The flight attendant, a black woman with curly hair who sat near Row 21, was wonderful and kind.

10.0 ExcellentMax, Oct 2025DCA - SAV
Read more American Airlines reviews

The flight attendant, a black woman with curly hair who sat near Row 21, was wonderful and kind.

It was good..clean, comfy seat. Friendly warm welcoming crew. Was able to check my cabin luggage at the gate which I was able to pickup in a decent time from baggage claim. The app gave all updates from delays to baggage claim info. Overall smooth flight.

Flight was delayed leaving Dallas. Arrived about 2 hours later than scheduled.

Flight delayed and missed connection. Rescheduled flight cancelled after 6 hrs wait. Rerouted thru ORD, flight cancelled, overnight stay in ORD. Still in the air on new flight!

We are too tired and frustrated to comment politely at this point

Terrible. Our luggage was delayed and couldn’t be delivered for several days. We got bad information from the airline agents at baggage claim. We had to pick up our car so we wouldn’t be charged for an extra day. We got lost in the maze of airport parking. The baggage claim agents didn’t offer us any compensation for our extra time and expense. We are tired, hungry and very frustrated.

The flight was flawless and we even arrived between 20 and 25 minutes early!

The only thing to like was that we eventually got to our destination

Delayed delayed delayed and no offer for food or vouchers

Disliked having to wait a little longer to disembark from the plan when we landed in London

Everything you need to know for your flight from St. Louis to Santiago de los Caballeros

Information on your arrival and departure airports

St. Louis (STL)
Santiago de los Caballeros (STI)

Not what you’re looking for? Find thousands of other hotels, flights, car rentals and package deals with KAYAK.