STL - STI

$451 Find Cheap Flights from St. Louis to Santiago de los Caballeros - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from St. Louis to Santiago de los Caballeros departing on 8/15. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$600
American Airlines
Fri 1/8Fri 1/22
STL - STI • 1 stop
Cheapest one-way
$451
Frontier
Sat 8/15
STL - STI • 2 stops
Top airlines
Cheapest • from $600 (round-trip)
Best reviews • 7.4 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between St. Louis and Santiago de los Caballeros. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $699 (round-trip)
Shortest trip • 7h 52m (one-way)
Insights
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We hope you love your trip to Santiago de los Caballeros!
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Booking Insights
Flight Deals

Cheap Flights from St. Louis to Santiago de los Caballeros (STL-STI)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from St. Louis to Santiago de los Caballeros that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from St. Louis to Santiago de los Caballeros

Fri, Jan 8 - Fri, Jan 22
American Airlines Logo
5:15 am - 9:43 pm
STL
-
STI
14h 28m
1 stop
American Airlines Logo
6:02 am - 5:24 pm
STI
-
STL
13h 22m
1 stop
$600American Airlines
Mon, Sep 14 - Mon, Sep 21
United Airlines Logo
7:00 am - 10:52 pm
STL
-
STI
14h 52m
1 stop
United Airlines Logo
4:23 pm - 11:38 pm
STI
-
STL
8h 15m
1 stop
$600United Airlines
Mon, Sep 14 - Mon, Sep 21
United Airlines Logo
8:00 am - 10:52 pm
STL
-
STI
13h 52m
2 stops
United Airlines Logo
4:23 pm - 11:38 pm
STI
-
STL
8h 15m
1 stop
$605United Airlines
Fri, Jan 8 - Fri, Jan 22
American Airlines Logo
6:00 am - 9:43 pm
STL
-
STI
13h 43m
2 stops
American Airlines Logo
6:02 am - 2:47 pm
STI
-
STL
10h 45m
2 stops
$605American Airlines
Fri, Jan 8 - Fri, Jan 22
American Airlines Logo
5:15 am - 9:43 pm
STL
-
STI
14h 28m
1 stop
American Airlines Logo
6:02 am - 4:14 pm
STI
-
STL
12h 12m
2 stops
$605American Airlines
Mon, Sep 14 - Mon, Sep 21
Delta Logo
5:47 pm - 12:26 pm
STL
-
STI
17h 39m
2 stops
Delta Logo
7:30 pm - 1:06 pm
STI
-
STL
18h 36m
2 stops
$625Delta
Fri, Nov 6 - Tue, Nov 10
American Airlines Logo
6:15 pm - 1:25 pm
STL
-
STI
17h 10m
1 stop
American Airlines Logo
5:08 pm - 10:52 am
STI
-
STL
19h 44m
2 stops
$625American Airlines
Sat, Oct 10 - Tue, Oct 13
American Airlines Logo
5:23 pm - 2:12 pm
STL
-
STI
19h 49m
2 stops
American Airlines Logo
3:12 pm - 8:46 am
STI
-
STL
18h 34m
2 stops
$625American Airlines
Fri, Nov 6 - Tue, Nov 10
United Airlines Logo
6:00 am - 11:49 am
STL
-
STI
27h 49m
1 stop
United Airlines Logo
12:55 pm - 9:52 pm
STI
-
STL
10h 57m
1 stop
$753United Airlines
Mon, Oct 19 - Wed, Oct 21
United Airlines Logo
7:30 am - 10:52 pm
STL
-
STI
14h 22m
1 stop
United Airlines Logo
2:07 pm - 9:25 pm
STI
-
STL
8h 18m
1 stop
$774United Airlines
Booking Insights

KAYAK's insights & trends for St. Louis to Santiago de los Caballeros flights

Get data-powered insights and trends into flights from St. Louis to Santiago de los Caballeros to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from St. Louis to Santiago de los Caballeros?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 5 days.

In the past 5 days, the cheapest round-trip tickets from St. Louis to Santiago de los Caballeros were found on United Airlines ($600) and American Airlines ($625).

Good to know

Cheapest flight

$451
Flight from St. Louis to Santiago de los Caballeros

When to book flights from St. Louis to Santiago de los Caballeros

Are your dates flexible? Find out the best times to travel from St. Louis to Santiago de los Caballeros based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from St. Louis to Santiago de los Caballeros

  • What is the cheapest flight from St. Louis to Santiago de los Caballeros?

    In the last 5 days, the lowest price for a flight from St. Louis to Santiago de los Caballeros was $451 for a one-way ticket and $600 for a round-trip.

  • Do I need a passport to fly between St. Louis and Santiago de los Caballeros?

    Yes, you'll most likely have to show a valid passport before boarding the plane in St. Louis and on arrival in Santiago de los Caballeros.

  • Which aircraft models fly most regularly from St. Louis to Santiago de los Caballeros?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from St. Louis to Santiago de los Caballeros?

    oneworld, and Star Alliance are the airline alliances operating flights between St. Louis and Santiago de los Caballeros, with oneworld being the most commonly used for this route.

  • Which is the best airline for flights from St. Louis to Santiago de los Caballeros, United Airlines or American Airlines?

    The two airlines most popular with KAYAK users for flights from St. Louis to Santiago de los Caballeros are United Airlines and American Airlines. With an average price for the route of $636 and an overall rating of 7.4, United Airlines is the most popular choice. American Airlines is also a great choice for the route, with an average price of $638 and an overall rating of 7.1.

  • How does KAYAK find such low prices on flights from St. Louis to Santiago de los Caballeros?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from St. Louis to Santiago de los Caballeros.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from St. Louis to Santiago de los Caballeros?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santiago de los Caballeros from St. Louis is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from St. Louis to Santiago de los Caballeros?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santiago de los Caballeros with an airline and back to St. Louis with another airline. Booking your flights between St. Louis and STI can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from St. Louis to Santiago de los Caballeros?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santiago de los Caballeros from St. Louis up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from St. Louis to Santiago de los Caballeros

 
See real verified KAYAK customer reviews for airlines flying from St. Louis to Santiago de los Caballeros. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from St. Louis to Santiago de los Caballeros? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 10058 reviews
7.7Boarding
7.3Comfort
7.1Entertainment
8.1Crew
6.7Food
Airline reviews

I almost missed my connection in Chicago due to having to wait on a gate to be open I am assuming. Having to run from E terminal to C terminal and I barely made it there before they closed the door. This may not be the actual airline's fault it's crazy how there is so little time between flight especially when they are placed so far apart in the airport.

8.0 ExcellentSherry, Jul 2026
COU - ORD
Read more United Airlines reviews

I almost missed my connection in Chicago due to having to wait on a gate to be open I am assuming. Having to run from E terminal to C terminal and I barely made it there before they closed the door. This may not be the actual airline's fault it's crazy how there is so little time between flight especially when they are placed so far apart in the airport.

Our flight was great with an unexpected upgrade. However, four days into our travel we are still without a piece of luggage. The bag tracker has not been accurate, the airline is not communicating with me or the luggage delivery service and no one is willing to take responsibility or guarantee any kind of support or reimbursement. Unfortunately, we do not have the option to easily shop to replace items as we are currently on a cruise. I have been very disappointed by United Airlines response.

Fine not above and beyond as I had a connection that was delayed due to maintenance

HORRIBLE, my initial flight was cancelled, they made me pay $200 extra dollars and that got cancelled as well! After 6 cancellations I decided to get a refund because I needed to get home to my babies. Out of $1000+ dollars they offered me only $40 in refund! Totally unacceptable! The flight that they cancelled I was able to fly it on another airline. I had to spend $400 on one way tickets just to get home! I’m still getting the runaround.

Flight was delayed. De-icing took a while. When we landed had to wait for another plane to vacate our gate. Just an overall bad experience.

Flight was delayed only slightly before takeoff due to traffic control. However, the flight arrived early to ORD. Good flight. United has been very reliable for me.

Our flight was understandably diverted to a small regional airport in Laramie, Wyoming due to weather conditions, which I fully recognize and appreciate. However, the low rating stems from the experience that followed: passengers remained on board for over an hour without the option to deplane and stretch, despite the aircraft being stationary. Although the pilot opened the cabin door, only he was permitted to exit. Meanwhile, passengers grew increasingly uncomfortable as warm summer air entered the cabin through the open door, and being in the second row meant we were impacted immediately. While the flight attendants made efforts to keep everyone at ease, I believe allowing passengers to deplane briefly, given the extended delay, would have significantly improved the overall experience.

Overall a very poor experience - booked premium economy tickets but due to last minute flight delays , all my itinery went for a toss and had to fly economy class with no access to lounge or any compensation by united airlines to make up for the flight delays . i had expected better experience than that from united.

Onboarding - it would be great to see on the screen what group they were boarding. It was very confusing on who was boarding (even though they called it out) they were not clear and the space to board was strange.

Older plane. Food was really bad, almost not worth the effort. Huge difference with European based airlines.

My luggage was not sent with us. Not sure if this is Envoy Air responsibility but that was a very BAD experience

American delayed the flight for a crew rest period. The delay occurred late in the evening - the earliest i can find is 10:20 pm. With a 6 am flight anyone on the flight would have already have been asleep (unless you are insane, a vampire or on drugs) and at least for me i was already on the way to the airport at 445 am the next morning when i discovered they delayed the flight until 9 am. Given the incoming flight was in the air at 6 pm the evening before this should have been figured out a lot more timely that was there only crew to use. Just frustrating given there is no consideration for customer experience anymore in flying.

Good crew and flight was on time. It’s a small plane with limited overhead luggage space. They said the overhead space was full and I had to check my bag. There was still space when I got on. Waiting for my checked luggage added 30 minutes to my trip. Not the end of the world but also not great.

Trip delayed for 2 hours because of rain. We boarded and have to get down the flight and reboard again.

No enough space plus only allowing one laggage instead of two like other airlines.

Qatar airways ,boarding arrangements at Hamid international airport could been better

Two flight changes before the scheduled flight. On the day of the flight, the flight was delayed, which caused the connecting flight to be missed. Then, I was directed to another airport (CUN) and traveled to Tulum. American gave a $12 voucher for lunch. The least expensive item on the menu at a Mexican restaurant was $9.99. Driving to Tulum was a bad auto crash, and traffic was delayed two-plus hours. The bottom line is that we should have been at the hotel at noon, but it ended up at 11:30 PM.

Miami lounges were overcrowded and we were unable to get in. We only had a short time. But the banks are too tight in all American hubs

Overall boarding and debarking is a joke. I dont even bring luggage anymore on trips because you can never allow them to be place then in the overhead bin or you have to pay or you check them which is even worse having to wait for your luggage on the tarmac.

First time flying internationally with AA and probably my last. Not military friendly at all. Didn't allow free checked bag for military family members (dependents) on orders like other airlines. We were charged $100 for baggage weight overage (5 lbs!)even though we had military orders allowing us extra.. Didn’t allow military members to board early. Inefficient and long wait time to board. Seats are smaller and more uncomfortable than other airlines.. no drink service for over 7 hrs of flight! After initial meal was served, the crew never offered a snack or drinks until the breakfast's was served 1 1/2 hrs before landing. Overall expensive and poor experience for the entire flight.

Everything you need to know for your flight from St. Louis to Santiago de los Caballeros

Information on your arrival and departure airports