STL - STI

$485 Find Cheap Flights from St. Louis to Santiago de los Caballeros

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from St. Louis to Santiago de los Caballeros departing on 8/12. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Santiago de los Caballeros

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from St. Louis to Santiago de los Caballeros, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from St. Louis to Santiago de los Caballeros, as well as popular online travel agencies
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Flights Deals

Cheap Flights from St. Louis to Santiago de los Caballeros (STL-STI)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from St. Louis to Santiago de los Caballeros that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from St. Louis to Santiago de los Caballeros

Tue, Aug 12 - Sat, Aug 16
Spirit Airlines Logo
5:26 pm - 9:15 amSTL-STI
14h 49m1 stop
Spirit Airlines Logo
10:20 am - 9:40 amSTI-STL
24h 20m1 stop
$485Spirit Airlines
Find Deal
Tue, Aug 12 - Sat, Aug 16
Spirit Airlines Logo
5:26 pm - 9:15 amSTL-STI
14h 49m1 stop
Spirit Airlines Logo
10:20 am - 1:32 pmSTI-STL
28h 12m2 stops
$535Spirit Airlines
Find Deal
Tue, Aug 12 - Sat, Aug 16
Spirit Airlines Logo
5:26 pm - 9:15 amSTL-STI
14h 49m1 stop
Spirit Airlines Logo
10:20 am - 1:32 pmSTI-STL
28h 12m3 stops
$550Spirit Airlines
Find Deal
Tue, Aug 19 - Tue, Sep 16
American Airlines Logo
5:26 am - 12:31 pmSTL-STI
6h 05m1 stop
American Airlines Logo
1:29 pm - 11:59 pmSTI-STL
11h 30m1 stop
$560American Airlines
Find Deal
Tue, Aug 19 - Tue, Sep 16
American Airlines Logo
6:00 am - 8:48 pmSTL-STI
13h 48m2 stops
American Airlines Logo
1:29 pm - 11:59 pmSTI-STL
11h 30m1 stop
$564American Airlines
Find Deal
Tue, Aug 12 - Mon, Aug 18
Frontier Logo
5:40 pm - 12:51 pmSTL-STI
18h 11m2 stops
Frontier Logo
2:06 pm - 11:47 pmSTI-STL
10h 41m2 stops
$567Frontier
Find Deal
Tue, Aug 12 - Sun, Aug 17
Spirit Airlines Logo
5:26 pm - 9:15 amSTL-STI
14h 49m1 stop
Spirit Airlines Logo
10:20 am - 1:32 pmSTI-STL
28h 12m2 stops
$575Spirit Airlines
Find Deal
Tue, Aug 12 - Sat, Aug 16
 Logo
9:50 am - 9:15 amSTL-STI
22h 25m3 stops
 Logo
10:20 am - 1:32 pmSTI-STL
28h 12m3 stops
Tue, Aug 12 - Sun, Aug 17
 Logo
9:50 am - 9:15 amSTL-STI
22h 25m3 stops
 Logo
10:20 am - 1:32 pmSTI-STL
28h 12m3 stops
Mon, Aug 11 - Sun, Aug 17
United Airlines Logo
6:00 am - 3:12 pmSTL-STI
8h 12m1 stop
United Airlines Logo
2:07 pm - 11:43 pmSTI-STL
10h 36m1 stop
$968United Airlines
Find Deal
Booking Insights

KAYAK's insights & trends for St. Louis to Santiago de los Caballeros flights

Get data-powered insights and trends into flights from St. Louis to Santiago de los Caballeros to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from St. Louis to Santiago de los Caballeros?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from St. Louis to Santiago de los Caballeros were found on Spirit Airlines ($485) and American Airlines ($560).

Good to know

Low seasonSeptember
Cheapest flight$485
Best time to beat the crowds with an average 26% drop in price.
Most popular time to fly with an average 30% increase in price.
Flight from St. Louis to Santiago de los Caballeros

When to book flights from St. Louis to Santiago de los Caballeros

Are your dates flexible? Find out the best times to travel from St. Louis to Santiago de los Caballeros based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from St. Louis to Santiago de los Caballeros

  • What is the cheapest flight from St. Louis to Santiago de los Caballeros?

    In the last 3 days, the lowest price for a flight from St. Louis to Santiago de los Caballeros was $485 for a round-trip ticket.

  • Do I need a passport to fly between St. Louis and Santiago de los Caballeros?

    Yes, you'll most likely have to show a valid passport before boarding the plane in St. Louis and on arrival in Santiago de los Caballeros.

  • Which aircraft models fly most regularly from St. Louis to Santiago de los Caballeros?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from St. Louis to Santiago de los Caballeros?

    oneworld, and Star Alliance are the airline alliances operating flights between St. Louis and Santiago de los Caballeros, with oneworld being the most commonly used for this route.

  • How does KAYAK find such low prices on flights from St. Louis to Santiago de los Caballeros?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from St. Louis to Santiago de los Caballeros.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from St. Louis to Santiago de los Caballeros?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santiago de los Caballeros from St. Louis is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from St. Louis to Santiago de los Caballeros?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santiago de los Caballeros with an airline and back to St. Louis with another airline. Booking your flights between St. Louis and STI can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from St. Louis to Santiago de los Caballeros?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santiago de los Caballeros from St. Louis up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from St. Louis to Santiago de los Caballeros

 
See real verified KAYAK customer reviews for airlines flying from St. Louis to Santiago de los Caballeros. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from St. Louis to Santiago de los Caballeros? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 10000 reviews
7.2Comfort
7.5Boarding
8.0Crew
6.9Entertainment
6.5Food
Airline reviews

Very poor delay in dfw was really bad n long

2.0 Mediocredavix, Jul 2025DFW - MKE
Read more American Airlines reviews

Very poor delay in dfw was really bad n long

Our flight was 1.5 hours delayed. There was no weather for the inbound flight, so I don't understand why. This meant a VERY late arrival and only a quick nap before my morning flight.

Because of rescheduling, they had to put me on a flight that didn't go through Dallas

It was very difficult to stretch my knee out and I am very short. I also had a torn tendon in my knee which made it extra uncomfortable anyways. My husband is 6'2" and I can't imagine him flying in that plane.

3 hour weather delay followed by 1 hour (and counting) maintenance delay. UGH!

Couldn’t get the door on the plane to close leading to a nearly 2 hour delay. But, hey at least they didn’t cancel the flight.

Flight was cancelled 3 hrs AFTER etd. Thetefore Missed connection from JFK to New Zealand . No accommodation provided… This cost ne aporox 1000 USD in extra expenses and turned whst should have been a 24 hr trip ftom Boston - New Zealand into a VERY expensive , late 70+ hr nightmare … Complete nonsense!!!

After we'd boarded , they canceled the flight. The crew didn't even know , we just all received text messages. Then after they deplaned us , AA was just like "too bad, go F your self, we sure ain't gonna help you"

The plane was broken so we had to change planes.

The flight got delayed 2.5 hrs due to a maintenance issue that cause a domino effect. American should have spare planes for when something like this happens.

Everything you need to know for your flight from St. Louis to Santiago de los Caballeros

Information on your arrival and departure airports

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