STL - STI

$338 Find Cheap Flights from St. Louis to Santiago de los Caballeros

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from St. Louis to Santiago de los Caballeros departing on 12/24. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santiago de los Caballeros

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from St. Louis to Santiago de los Caballeros, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from St. Louis to Santiago de los Caballeros, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$518
American Airlines
Wed 2/18Fri 2/27
STL - STI • 1 stop
Cheapest one-way
$338
American Airlines
Wed 12/24
STL - STI • 1 stop
Top airlines
American Airlines
Cheapest • from $518 (round-trip)
American Airlines
Best reviews • 7.2 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Santiago de los Caballeros!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from St. Louis to Santiago de los Caballeros (STL-STI)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from St. Louis to Santiago de los Caballeros that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from St. Louis to Santiago de los Caballeros

Wed, Feb 18 - Fri, Feb 27
American Airlines Logo
5:05 am - 1:31 pm
STL
-
STI
6h 26m1 stop
American Airlines Logo
8:00 am - 5:27 pm
STI
-
STL
11h 27m1 stop
$518American Airlines
Wed, Feb 18 - Fri, Feb 27
Delta Logo
6:00 am - 1:34 am
STL
-
STI
17h 34m2 stops
Delta Logo
9:59 pm - 3:55 pm
STI
-
STL
19h 56m2 stops
$522Delta
Sat, Feb 21 - Sat, Feb 28
American Airlines Logo
6:56 pm - 1:31 pm
STL
-
STI
16h 35m2 stops
American Airlines Logo
8:00 am - 10:05 pm
STI
-
STL
16h 05m1 stop
$532American Airlines
Sat, Feb 21 - Sat, Feb 28
American Airlines Logo
6:07 pm - 1:31 pm
STL
-
STI
17h 24m1 stop
American Airlines Logo
2:33 pm - 10:05 pm
STI
-
STL
9h 32m1 stop
$540American Airlines
Sun, Feb 1 - Thu, Feb 5
United Airlines Logo
6:30 am - 11:51 pm
STL
-
STI
15h 21m2 stops
United Airlines Logo
4:00 pm - 12:29 pm
STI
-
STL
22h 29m2 stops
$692United Airlines
Thu, Jan 1 - Fri, Jan 2
Multiple Airlines Logo
11:51 am - 2:42 am
STL
-
STI
12h 51m1 stop
Multiple Airlines Logo
3:43 am - 9:40 am
STI
-
STL
31h 57m2 stops
$797Multiple Airlines
Fri, Dec 26 - Sat, Jan 3
Multiple Airlines Logo
4:27 pm - 2:42 am
STL
-
STI
32h 15m2 stops
Multiple Airlines Logo
3:43 am - 10:56 am
STI
-
STL
9h 13m1 stop
$983Multiple Airlines
Thu, Jan 1 - Sat, Jan 3
American Airlines Logo
5:00 am - 9:04 pm
STL
-
STI
14h 04m2 stops
American Airlines Logo
3:24 pm - 8:35 am
STI
-
STL
19h 11m2 stops
$994American Airlines
Thu, Jan 1 - Sat, Jan 3
United Airlines Logo
11:48 am - 11:51 pm
STL
-
STI
10h 03m1 stop
United Airlines Logo
4:00 pm - 11:43 pm
STI
-
STL
9h 43m1 stop
$1,542United Airlines
Fri, Dec 26 - Sun, Jan 4
American Airlines Logo
6:00 pm - 5:27 pm
STL
-
STI
21h 27m1 stop
American Airlines Logo
6:00 am - 10:35 pm
STI
-
STL
18h 35m1 stop
$1,638American Airlines
Booking Insights

KAYAK's insights & trends for St. Louis to Santiago de los Caballeros flights

Get data-powered insights and trends into flights from St. Louis to Santiago de los Caballeros to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from St. Louis to Santiago de los Caballeros?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from St. Louis to Santiago de los Caballeros were found on American Airlines ($518) and Delta ($522).

Which airlines fly non-stop between St. Louis and Santiago de los Caballeros?

Airline and price data is aggregated from results in KAYAK’s search results from the last 2 weeks for round-trip flights from St. Louis to Santiago de los Caballeros.

There is just one airline that flies from St. Louis to Santiago de los Caballeros direct and that is American Airlines. The best round-trip deal found from American Airlines for the route is $604.

Find deals

Good to know

Low seasonOctober
Cheapest flight$338
Best time to beat the crowds with an average 23% drop in price.
Flight from St. Louis to Santiago de los Caballeros

When to book flights from St. Louis to Santiago de los Caballeros

Are your dates flexible? Find out the best times to travel from St. Louis to Santiago de los Caballeros based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from St. Louis to Santiago de los Caballeros

  • What is the cheapest flight from St. Louis to Santiago de los Caballeros?

    In the last 3 days, the lowest price for a flight from St. Louis to Santiago de los Caballeros was $338 for a one-way ticket and $518 for a round-trip.

  • Do I need a passport to fly between St. Louis and Santiago de los Caballeros?

    Yes, you'll most likely have to show a valid passport before boarding the plane in St. Louis and on arrival in Santiago de los Caballeros.

  • Which aircraft models fly most regularly from St. Louis to Santiago de los Caballeros?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from St. Louis to Santiago de los Caballeros?

    oneworld is the only airline alliance operating flights between St. Louis and Santiago de los Caballeros.

  • How does KAYAK find such low prices on flights from St. Louis to Santiago de los Caballeros?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from St. Louis to Santiago de los Caballeros.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from St. Louis to Santiago de los Caballeros?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santiago de los Caballeros from St. Louis is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from St. Louis to Santiago de los Caballeros?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santiago de los Caballeros with an airline and back to St. Louis with another airline. Booking your flights between St. Louis and STI can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from St. Louis to Santiago de los Caballeros?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santiago de los Caballeros from St. Louis up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from St. Louis to Santiago de los Caballeros

 
See real verified KAYAK customer reviews for airlines flying from St. Louis to Santiago de los Caballeros. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from St. Louis to Santiago de los Caballeros? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 11050 reviews
8.0Crew
7.5Boarding
7.2Comfort
6.5Food
6.9Entertainment
Airline reviews

it was fine, decent flight... dont get food besides cookies or pretzels so not sure why you ask about food. same for entertainment..

8.0 ExcellentConnie, Dec 2025
PHX - MKE
Read more American Airlines reviews

it was fine, decent flight... dont get food besides cookies or pretzels so not sure why you ask about food. same for entertainment..

I got sick nothing contagious but distressing and the care I received by Kayla? Keighly the flight attendant will be memorable for ever. Thank You

I got sick nothing contagious but distressing enough and the care I received on the flight was astounding.

Waaay too small plane. They also need to up the size of the overhead bins. I would love to keep me 3k with of camera equipment in my hard case baggahe instead of it being thrown into the belly of the plane

Attendants were pleasant and the flight was smooth and relaxed.

A little late at the start but all worked out well.

It was fine. No drinks nor snacks offered though. I thought that was unusual.

I liked the humor of the captain and crew on the flight from Flagstaff to Dallas. They were humorous.

AA delayed the flight for 3 hours and 50 minutes, but delayed the last 2 hours, 30 minutes at a time, so if we knew before, could have stayed at home and worked instead of being at the airport wasting time... The plane's crew was excellent, not their fault.

After arriving in Dallas, the aircraft taxied for an unusually long time and was unable to park at the gate, which caused a significant delay and made me miss my connecting flight. I then had to wait in a very long line to be rebooked, and I was told that no hotel or meal accommodations would be provided. What is even more unacceptable is that my luggage was mishandled and has still not been located. My suitcase contains important medications that I urgently need, and I have been unable to access them due to the airline’s mishandling. This situation has caused me considerable stress and inconvenience, and I need this issue to be resolved immediately.

Everything you need to know for your flight from St. Louis to Santiago de los Caballeros

Information on your arrival and departure airports

St. Louis (STL)
Santiago de los Caballeros (STI)