MDE - CUZ

$229 Find Cheap Flights from Medellín to Cusco

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Medellín to Cusco departing on 5/19. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Cusco

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Medellín to Cusco, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Medellín to Cusco, as well as popular online travel agencies
Travelers love KAYAK
41.299.237 searches in the past 7 days on KAYAK

Save 23% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Everything you should know

Cheapest round-trip
$347
Typical prices: $298-$382
JetSMART
Tue 5/5Wed 5/13
MDE - CUZ • 1 stop
Cheapest one-way
$229
Typical prices: $201-$260
JetSMART
Tue 5/19
MDE - CUZ • 1 stop
Top airlines
Cheapest • from $347 (round-trip)
Best reviews • 7.4 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Medellín and Cusco. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $492 (round-trip)
Shortest trip • 7h 30m (one-way)
Insights
Insights
Insights
Insights
When to book
in advance
Our data shows that travelers who book at least 4 weeks in advance save around 11% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
Cheapest • 9% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Cusco!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Medellín to Cusco (MDE-CUZ)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Medellín to Cusco that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Medellín to Cusco

Tue, May 5 - Wed, May 13
JetSMART Logo
5:25 pm - 8:20 pm
MDE
-
CUZ
26h 55m
1 stop
JetSMART Logo
9:45 pm - 4:40 pm
CUZ
-
MDE
18h 55m
1 stop
$347JetSMART
Wed, Apr 22 - Wed, Apr 29
JetSMART Logo
5:25 pm - 6:40 am
MDE
-
CUZ
13h 15m
1 stop
JetSMART Logo
7:00 am - 4:40 pm
CUZ
-
MDE
9h 40m
1 stop
$358JetSMART
Thu, Apr 9 - Wed, Apr 15
JetSMART Logo
5:25 pm - 6:15 am
MDE
-
CUZ
12h 50m
1 stop
JetSMART Logo
9:00 am - 4:40 pm
CUZ
-
MDE
7h 40m
1 stop
$374JetSMART
Sat, May 30 - Sun, Jun 7
JetSMART Logo
5:25 pm - 8:25 pm
MDE
-
CUZ
27h 00m
1 stop
JetSMART Logo
10:05 pm - 4:40 pm
CUZ
-
MDE
18h 35m
1 stop
$380JetSMART
Sat, Apr 25 - Mon, Apr 27
JetSMART Logo
5:25 pm - 6:25 am
MDE
-
CUZ
13h 00m
1 stop
JetSMART Logo
7:00 am - 4:40 pm
CUZ
-
MDE
9h 40m
1 stop
$381JetSMART
Mon, Jul 27 - Fri, Jul 31
JetSMART Logo
5:25 pm - 6:25 am
MDE
-
CUZ
13h 00m
1 stop
JetSMART Logo
7:10 am - 4:40 pm
CUZ
-
MDE
9h 30m
1 stop
$399JetSMART
Fri, Apr 10 - Tue, Apr 14
JetSMART Logo
5:25 pm - 6:30 am
MDE
-
CUZ
13h 05m
1 stop
JetSMART Logo
7:00 am - 4:40 pm
CUZ
-
MDE
9h 40m
1 stop
$400JetSMART
Fri, Apr 10 - Tue, Apr 14
JetSMART Logo
5:25 pm - 6:30 am
MDE
-
CUZ
13h 05m
1 stop
JetSMART Logo
7:00 am - 4:40 pm
CUZ
-
MDE
9h 40m
1 stop
$405JetSMART
Mon, Jun 15 - Sat, Jun 20
JetSMART Logo
5:25 pm - 6:25 am
MDE
-
CUZ
13h 00m
1 stop
JetSMART Logo
7:10 am - 4:40 pm
CUZ
-
MDE
9h 30m
1 stop
$407JetSMART
Tue, May 26 - Sun, May 31
JetSMART Logo
5:25 pm - 6:25 am
MDE
-
CUZ
13h 00m
1 stop
JetSMART Logo
7:40 am - 4:40 pm
CUZ
-
MDE
9h 00m
1 stop
$417JetSMART
Booking Insights

KAYAK's insights & trends for Medellín to Cusco flights

Get data-powered insights and trends into flights from Medellín to Cusco to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Medellín Jose Maria Cordova Intl Airport to Cusco?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Medellín Jose Maria Cordova Intl Airport to Cusco departing in May.

What is the cheapest month to fly from Medellín Jose Maria Cordova Intl Airport to Cusco?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Medellín Jose Maria Cordova Intl Airport to Cusco, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Medellín Jose Maria Cordova Intl Airport to Cusco is May, where tickets cost $319 (return) on average. On the other hand, the most expensive months are October and February, where the average cost of round-trip tickets is $375 and $371 respectively.

How far in advance should I book a flight from Medellín Jose Maria Cordova Intl Airport to Cusco?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Medellín Jose Maria Cordova Intl Airport to Cusco, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Medellín Jose Maria Cordova Intl Airport to Cusco, you should book around 4 weeks before departure, which saves you about 11% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 25 weeks before departure.

Good to know

Low seasonFebruary
Cheapest flight$229
Best time to beat the crowds but there is an average 5% increase in price.
Most popular time to fly with an average 4% increase in price.
Flight from Medellín to Cusco

When to book flights from Medellín to Cusco

Are your dates flexible? Find out the best times to travel from Medellín to Cusco based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking Medellín to Cusco flights

  • What is the cheapest flight from Medellín Jose Maria Cordova Intl Airport to Cusco?

    In the last 3 days, the lowest price for a flight from Medellín Jose Maria Cordova Intl Airport to Cusco was $229 for a one-way ticket and $347 for a round-trip.

  • Do I need a passport to fly between Medellín and Cusco?

    Yes, you'll most likely have to show a valid passport before boarding the plane in Medellín and on arrival in Cusco.

  • Which aircraft models fly most regularly from Medellín to Cusco?

    We unfortunately don’t have that data for this specific route.

  • How does KAYAK find such low prices on flights from Medellín to Cusco?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Medellín to Cusco.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Medellín to Cusco?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Cusco from Medellín is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Medellín to Cusco?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Cusco with an airline and back to Medellín with another airline. Booking your flights between Medellín and CUZ can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Medellín to Cusco?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Cusco from Medellín up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Medellín to Cusco

 
See real verified KAYAK customer reviews for airlines flying from Medellín to Cusco. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Medellín to Cusco? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
LATAM AirlinesOverall score based on 1918 reviews
7.0Entertainment
7.3Comfort
6.7Food
8.0Crew
7.5Boarding
Airline reviews

LATAM is a great airline who takes care of there guests. They consistently walk around and see if you need water in addition to taking care of all the passengers. The chicken in process is really easy and I’m always offered a chance for an upgrade which I appreciate.

10.0 ExcellentChris, Feb 2026
GRU - MCO
Read more LATAM Airlines reviews

LATAM is a great airline who takes care of there guests. They consistently walk around and see if you need water in addition to taking care of all the passengers. The chicken in process is really easy and I’m always offered a chance for an upgrade which I appreciate.

Good check in process Poor information on payments at Lima airport

On board crew was very good. Crew was friendly, snacks were good, especially the chips. Seats seemed a bit cramped. Boarding seemed unorganized, as we were instructed to get to the gate an hour early and then just stood around until boarding.

We were not allowed to carry a bottle of water onto the 8 hour flight.

There was a mechanical issue with the plane that they had to work on before we could take off. That's fine, by all means, PLEASE make sure the mechanics are functioning properly. What was a problem was the fact that we sat on the tarmac for 4.5 hours without moving, without letting us off the plane, and without climate control and air running through the plane. There was no explanation as to what was going on; they just kept promising that it would be "15 minutes, then we are on our way." At one point, they even switched the entire crew out and told everyone we just needed to wait for new employees to show up. Then, as the 4 hours were not moving, an hour before the full refund, they made a big show about "the flight starting and the doors are locked, so you have to sit down." We didn't move for another 40 minutes; they were just trying to skirt around legalities that entitled us to restitution. When the flight finally was underway, the plane was gigantic but cramped in design, my entertainment screen kept freezing and glitching, and subtitles didn't work, and the crew was passive-aggressive. Terrible flight.

Comfort in exit seat was excellent. FLight crew and flight were excellent. However exit seat tray table was broken so could not use it. Entertainment monitor did not work at all despite attempts to reset it.

LATAM’s crews are fine, but God help you if you need any customer service. Their app and website never work, with error after error. Trying to solve anything over the phone is painful, and lastly, the boarding pass LATAM gave me to board the flight with Delta was invalid and I had to purchase an emergency one-way ticket at the last minute to get home.

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

we were missing our luggage, trying to find someone to have any empathy was pretty much not happening....

Everything you need to know for your flight from Medellín to Cusco

Information on your arrival and departure airports