$123 Find Cheap Flights from Milwaukee to South Carolina - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Milwaukee to South Carolina departing on 9/24. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Milwaukee to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Charleston
Charleston1 stop$323
Myrtle Beach
Myrtle Beach1 stop$293
Greenville
Greenville1 stop$259
Columbia
Columbia1 stop$271
Florence
Florence1 stop$630
Charlotte
Charlotte1 stop$232
Charleston
Charleston1 stop$323
Myrtle Beach
Myrtle Beach1 stop$293
Greenville
Greenville1 stop$259
Columbia
Columbia1 stop$271
Florence
Florence1 stop$630
Charlotte
Charlotte1 stop$232

Book Cheap Milwaukee to South Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Milwaukee to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Milwaukee to South Carolina

Thu, Sep 3 - Mon, Sep 7
Frontier Logo
12:10 pm - 1:50 pm
MKE
-
CLT
24h 40m
1 stop
Frontier Logo
9:52 pm - 11:13 am
CLT
-
MKE
14h 21m
1 stop
$232Frontier
Thu, Sep 10 - Thu, Sep 10
American Airlines Logo
8:03 am - 11:09 am
MKE
-
CLT
2h 06mnonstop
American Airlines Logo
2:35 pm - 9:54 pm
CLT
-
MKE
8h 19m
1 stop
$250American Airlines
Tue, Aug 25 - Wed, Aug 26
Frontier Logo
12:10 pm - 8:01 am
MKE
-
CLT
18h 51m
1 stop
Frontier Logo
9:52 pm - 11:13 am
CLT
-
MKE
14h 21m
1 stop
$256Frontier
Sat, Oct 17 - Tue, Oct 20
United Airlines Logo
6:15 am - 1:35 pm
MKE
-
GSP
6h 20m
1 stop
United Airlines Logo
6:20 am - 10:07 am
GSP
-
MKE
4h 47m
1 stop
$259United Airlines
Wed, Aug 19 - Sat, Aug 22
American Airlines Logo
5:00 am - 11:00 am
MKE
-
GSP
5h 00m
1 stop
American Airlines Logo
8:10 am - 2:04 pm
GSP
-
MKE
6h 54m
1 stop
$259American Airlines
Tue, Aug 25 - Tue, Sep 1
Southwest Logo
7:40 am - 12:25 pm
MKE
-
GSP
3h 45m
1 stop
Southwest Logo
1:20 pm - 8:30 pm
GSP
-
MKE
8h 10m
2 stops
$264Southwest
Sun, Sep 6 - Wed, Sep 9
United Airlines Logo
10:19 am - 5:02 pm
MKE
-
GSP
5h 43m
1 stop
United Airlines Logo
10:33 am - 2:33 pm
GSP
-
MKE
5h 00m
1 stop
$264United Airlines
Wed, Sep 9 - Tue, Sep 15
Delta Logo
10:11 am - 3:27 pm
MKE
-
HHH
4h 16m
1 stop
Delta Logo
4:17 pm - 9:20 pm
HHH
-
MKE
6h 03m
1 stop
$271Delta
Wed, Sep 9 - Tue, Sep 15
Delta Logo
7:14 am - 3:27 pm
MKE
-
HHH
7h 13m
2 stops
Delta Logo
4:17 pm - 9:20 pm
HHH
-
MKE
6h 03m
1 stop
$276Delta
Sat, Sep 12 - Sat, Sep 19
Southwest Logo
7:30 am - 3:40 pm
MKE
-
MYR
7h 10m
1 stop
Southwest Logo
5:00 pm - 8:40 pm
MYR
-
MKE
4h 40m
1 stop
$293Southwest
Booking Insights

KAYAK's insights & trends for Milwaukee to South Carolina flights

Get data-powered insights and trends into flights from Milwaukee to South Carolina to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Milwaukee to South Carolina?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Milwaukee to South Carolina departing in October.

Flight prices are below average for this route right now.

Flights to South Carolina from Milwaukee usually cost between $387 and $426 in October.
The lowest price found in the past 5 days was $323 on Multiple Airlines (Oct 17-Oct 21).

What is the cheapest month to fly from Milwaukee to South Carolina?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Milwaukee to South Carolina, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Milwaukee to South Carolina is November, when tickets cost $341 (return) on average. On the other hand, the most expensive months are June and April, when the average cost of round-trip tickets is $425 and $420 respectively.

How far in advance should I book a flight from Milwaukee to South Carolina?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Milwaukee to South Carolina, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Milwaukee to South Carolina, you should book around 5 weeks before departure, which saves you about 52% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 16 weeks before departure.

Good to know

Low season

January

Cheapest flight

$123
Best time to beat the crowds with an average 17% drop in price.
Most popular time to fly and prices are also 1% lower on average.
Flight from Milwaukee to Charlotte

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Milwaukee to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Milwaukee to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Milwaukee to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Milwaukee to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Milwaukee to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Milwaukee to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Milwaukee to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Milwaukee to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Top tips for finding cheap flights to South Carolina

  • Looking for a cheap flight? 25% of our users found tickets from Milwaukee to the following destinations at these prices or less: Charlotte $219 one-way - $436 round-trip

Reviews of the top 4 airlines serving from Milwaukee to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Milwaukee to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Milwaukee to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4227 reviews
7.0Food
8.0Comfort
8.1Boarding
7.5Entertainment
8.6Crew
Airline reviews

No wifi, seems to be very common with Southwest currently. Everything else was normal.

8.0 ExcellentSean, Jul 2026
HOU - LGB
Read more Southwest reviews

No wifi, seems to be very common with Southwest currently. Everything else was normal.

Poor customer service, no accommodation for passengers when the flight was delayed over 5 hours.

Friendly crew kept coming by to make sure all was ok, provide additional refreshments, etc.

It was good. Last flight was delayed but I always say that is in God's plan

Red eye from San Diego. Temperature of the cabin was way too warm and the air duct flowed very little air.

Overall good, just screaming kids in the area the whole flight.

My experience will Southwest was good. I wish there was more entertainment and the boarding process was slow at time but other than that my experience was great definitely will be flying with SouthWest again.

I'm glad it wasn't only 75% full because I could get a good seat

Check-in, Boarding and flight were smooth. All the employees and crew was very nice and funny. They gave the kids crayons and workbooks to keep them occupied which was a big win. I’ve flown Southwest many times and that’s the first time I’ve seen that and it is a great addition.

We were headed for Florida and anxious to get there. Everything was absolutely the best. This is our first time with Southwest and it’s now our go to airline. Best ever.

Flight was delayed before take off and at landing. Baggage took 20 minutes. Flight crew would not serve full soft drink and had to ask multiple times before receiving water.

For some reason, TSA Atlanta didn’t have my bag on the flight on time and they don’t have to provide Delta a reason for that.

I am still at the Airport! Delayed Delayed and Delyaed

The landing was the worst I’ve experienced with a flight.

It was last minute due to weather - considering - it was amazing! Good smiles, friendly staff and they were making sure we knew what was going on when and where.

Staff was exceptional! Everyone was kind, professional and friendly making the trip very pleasant. Thank you!

Pretty standard flight. Delta has a good selection of movies.

All good on Delta's part. Passengers could be a little more courteous to each other.

The pilots were good. Disappointing when planes don't have electrical ports

Despite being delayed, we would still give a high score for this flight experience. For the first time in quite some time we had excellent customer service throughout our entire round trip. The flight attendants were the most polite we have experienced in our last ten flights at least (non of which were Delta and include business class). The food offered was a better selection than most—we just didn’t have any of it. Overall, almost as good as flying used to be. Thank you to Delta.

It was hot and not as comfortable as the flight to Chicago. Must have been a different plane that needs to be worked on or replaced.

My flight was delayed so bad i missed u it so i just said never mind

Wonderful flight! The crew was good, check-in was good and orderly and the flight was uneventful and good.

Awful. No counter attendants. No dinner offered due to delays.

The flight was delayed by two de-icings. The seatbelt did not work correctly. It did not stay tight.

The seats on the aircraft are like sitting in a rock. During the boarding process they recognize Active Duty Military, why don’t they recognize Retired Military. I’ve always preferred Delta, this flight confirmed why I still prefer Delta.

It was literally one of the worst travel experiences ever. My flight got delayed by over an hour and there was no communication of this from the gate staff. I realized it by checking the screen periodically. Once on board the flight attendants continued to serve alcohol to a man who was clearly already drunk and that was making a bunch of commotion. Never again will I fly United!

At least the delays were short. Business class, even in the new planes is very crowded now with crappy tray tables

All good except paid for wifi that did not work

Flight cancelled due to fog. No other flights available for 36 hours. Directed by United to book passage on another carrier, and submit receipts for reimbursement. Did that. United now states they will not reimburse. Currently out 2 grand.

Very turbulent flight, no drinks, very little service, unorganized boarding, gate changed multiple times

Crew was helpful and cheerful especially when they had no refreshments to work with. The plane was never serviced and had nothing but limited water and coffee onboard. For the price point, a concern of services.

I bought wifi and most of the flight could not even use it my apps would just spin. I couldn't even listen to music. super frustrating.

Poor seat in rear of aircraft Food at Admiral’s Club Terminal D at DFW inedible

There were several different delays but we ended up being delayed a total of 40 mins or so. It was annoying we had a gate change which made it take longer to leave DFW, and we had to check our carry on. Ugh

Multiple gate changes and significant delay leaving DFW. Made for a late arrival

For the price of the ticket you get nothing. The plane had 1 bathroom in the back and when the flight attendant did service no one could use it. No announcement just was told to go back to my seat. Ridiculous and rude.

In-flight Wi-Fi didn’t work and the flight was 25 minutes late. The Embraer plane I was on was pretty old and the tray table was broken.

We were told we had no flights before our flight was continually delayed then cancelled.

American Airlines no longer has Bischoff biscuits. This is intolerable.

Everything you need to know for your flight from Milwaukee to South Carolina

Information on your arrival and departure airports