ECP - CUZ

$1,464 Find Cheap Flights from Panama City to Cusco - Compare and Save

1 adult
1 adult, Economy, 0 bags

Save 26% or more on flights. Compare deals from all over the web.

Never overpay with our price tracking tools.

Filter searches by price, airline and more to find your best flights.

Everything you should know

Cheapest round-trip
$1,464
Typical prices: $1,116-$1,126
LATAM Airlines
Tue 4/17Fri 4/20
ECP - CUZ • 2 stops
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Cusco!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Panama City to Cusco (ECP-CUZ)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to Cusco

Sat, Apr 17 - Tue, Apr 20
LATAM Airlines Logo
11:15 am - 9:30 amECP  Panama City NW Florida Beaches-CUZ Cusco Velazco Astete
22h 15m2 stops Atlanta Hartsfield-Jackson Lima J Chavez Intl
LATAM Airlines Logo
7:10 am - 10:47 pmCUZ  Cusco Velazco Astete-ECP Panama City NW Florida Beaches
15h 37m2 stops Lima J Chavez Intl Atlanta Hartsfield-Jackson
$1,464LATAM Airlines
Sat, Apr 17 - Tue, Apr 20
LATAM Airlines Logo
2:47 pm - 8:45 amECP  Panama City NW Florida Beaches-CUZ Cusco Velazco Astete
17h 58m2 stops Atlanta Hartsfield-Jackson Lima J Chavez Intl
LATAM Airlines Logo
3:35 pm - 10:15 amCUZ  Cusco Velazco Astete-ECP Panama City NW Florida Beaches
18h 40m2 stops Lima J Chavez Intl Atlanta Hartsfield-Jackson
$1,514LATAM Airlines
Sun, Dec 6 - Sun, Dec 13
LATAM Airlines Logo
6:00 am - 6:35 amECP  Panama City NW Florida Beaches-CUZ Cusco Velazco Astete
23h 35m2 stops Atlanta Hartsfield-Jackson Lima J Chavez Intl
LATAM Airlines Logo
7:45 pm - 8:38 amCUZ  Cusco Velazco Astete-ECP Panama City NW Florida Beaches
13h 53m2 stops Lima J Chavez Intl Atlanta Hartsfield-Jackson
$1,602LATAM Airlines
Sun, Dec 6 - Sun, Dec 13
LATAM Airlines Logo
6:00 am - 10:30 pmECP  Panama City NW Florida Beaches-CUZ Cusco Velazco Astete
15h 30m3 stops Atlanta Hartsfield-Jackson Bogotá El Dorado Lima J Chavez Intl
LATAM Airlines Logo
7:45 pm - 8:38 amCUZ  Cusco Velazco Astete-ECP Panama City NW Florida Beaches
13h 53m2 stops Lima J Chavez Intl Atlanta Hartsfield-Jackson
$1,617LATAM Airlines
Mon, Dec 21 - Mon, Dec 28
LATAM Airlines Logo
6:00 am - 7:05 amECP  Panama City NW Florida Beaches-CUZ Cusco Velazco Astete
24h 05m2 stops Atlanta Hartsfield-Jackson Lima J Chavez Intl
LATAM Airlines Logo
8:00 pm - 8:37 amCUZ  Cusco Velazco Astete-ECP Panama City NW Florida Beaches
13h 37m2 stops Lima J Chavez Intl Atlanta Hartsfield-Jackson
$1,825LATAM Airlines
Mon, Dec 21 - Mon, Dec 28
American Airlines Logo
10:51 am - 10:20 amECP  Panama City NW Florida Beaches-CUZ Cusco Velazco Astete
22h 29m3 stops Charlotte Douglas Miami Lima J Chavez Intl
American Airlines Logo
9:30 pm - 6:32 pmCUZ  Cusco Velazco Astete-ECP Panama City NW Florida Beaches
22h 02m3 stops Lima J Chavez Intl Miami Charlotte Douglas
$2,590American Airlines
Booking Insights

Price, demand and travel trends for Panama City to Cusco flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from Panama City to Cusco?

Round-trip flights from Panama City to Cusco typically range from $1,116 to $1,126. The lowest price found in the past 5 days was $1,464, on LATAM Airlines.

Find deals

Key details for Panama City to Cusco flights

Cheapest flight

$1,464
Round-trip flight from Panama City to Cusco

When to book flights from Panama City to Cusco

Are your dates flexible? Find out the best times to travel from Panama City to Cusco based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Panama City to Cusco flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from Panama City to Cusco?

    Only Economy Class is available on flights from Panama City to Cusco.

  • Do I need a passport to fly from Panama City to Cusco?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • Have flight prices from Panama City to Cusco changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route varied from about $1,464 to $2,590. That means the highest observed fare was about 76% higher than the lowest one.

  • What car rental options are available at Cusco Velazco Astete Airport (CUZ)?

    Cusco Velazco Astete Airport (CUZ) hosts 5 major car rental companies, with daily rates averaging $46 for economy cars. Top options include:

    • Sixt
    • Hertz
    • Thrifty
    • Europcar
    • Dollar

  • Which airports can I use when flying from Panama City to Cusco?

    Flights from Panama City to Cusco usually depart from Panama City NW Florida Beaches (ECP) and arrive at Cusco Velazco Astete (CUZ).

  • Can I save money by using flexible dates for flights from Panama City to Cusco?

    Yes. Flexible dates can save you up to 1% on flights from Panama City to Cusco. Friday is the cheapest departure day at $1,116 round-trip on average, while Tuesday is the most expensive at $1,126, a difference of $10.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • What is the time difference between Panama City and Cusco?

    Cusco is 1 hour ahead of Panama City (Peru Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.

  • What popular places can I visit in Cusco?

    Some of the most popular sights in Cusco are Plaza de Armas, Cusco Cathedral and UNSAAC-Yale International Center for the Study of Machu Picchu and Inca Culture. These are among the most viewed places in Cusco on KAYAK.

Your guide to booking Panama City to Cusco flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Friday departure and avoid flying on Tuesday. On this route, Friday flights average $1,116, about $10 less than Tuesday fares (1% savings) based on the last 12 months.
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Cusco Velazco Astete Airport.

    • Ureta Hotel
    • Polo Corporativo San Sebastian
    • Hotel Paradis Suite Cusco

More options for your flight from Panama City to Cusco

Complete your trip to Cusco with a hotel stay or car rental

Car rentals in Cusco
Hotels in Cusco
Vacations in Cusco