$238 Find Cheap Flights from Panama City to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to South America departing on 3/10. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Panama City to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Bogotá
Bogotá2 stops$504
Guayaquil
Guayaquil2 stops$563
Bogotá
Bogotá2 stops$504
Guayaquil
Guayaquil2 stops$563

Book Cheap Panama City to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama City to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to South America

Fri, Feb 20 - Fri, Feb 27
American Airlines Logo
4:34 pm - 2:15 pm
ECP
-
BOG
20h 41m2 stops
American Airlines Logo
3:15 pm - 12:14 pm
BOG
-
ECP
21h 59m2 stops
$504American Airlines
Fri, Feb 20 - Fri, Feb 27
Avianca Logo
6:30 am - 10:35 pm
ECP
-
BOG
15h 05m1 stop
Avianca Logo
8:15 am - 9:56 pm
BOG
-
ECP
14h 41m1 stop
$515Avianca
Sat, May 9 - Fri, May 22
Delta Logo
7:45 am - 7:25 pm
ECP
-
BOG
11h 40m1 stop
Delta Logo
2:55 pm - 8:17 am
BOG
-
ECP
17h 22m1 stop
$524Delta
Sat, May 9 - Fri, May 22
Delta Logo
2:47 pm - 1:50 pm
ECP
-
BOG
23h 03m1 stop
Delta Logo
2:55 pm - 8:17 am
BOG
-
ECP
17h 22m1 stop
$530Delta
Sun, Mar 1 - Tue, Mar 31
United Airlines Logo
6:30 am - 5:33 pm
ECP
-
GYE
34h 03m2 stops
United Airlines Logo
8:31 am - 9:35 am
GYE
-
ECP
25h 04m2 stops
$563United Airlines
Sat, May 9 - Fri, May 22
American Airlines Logo
7:21 am - 9:17 pm
ECP
-
BOG
13h 56m2 stops
American Airlines Logo
2:10 pm - 10:25 am
BOG
-
ECP
20h 15m2 stops
$573American Airlines
Sat, May 9 - Fri, May 22
American Airlines Logo
12:33 pm - 10:30 pm
ECP
-
BOG
9h 57m1 stop
American Airlines Logo
12:25 pm - 10:25 am
BOG
-
ECP
22h 00m2 stops
$585American Airlines
Mon, Apr 13 - Wed, Apr 15
United Airlines Logo
4:57 pm - 4:54 am
ECP
-
BOG
11h 57m1 stop
United Airlines Logo
12:14 am - 9:35 am
BOG
-
ECP
9h 21m1 stop
$596United Airlines
Mon, Apr 13 - Thu, Apr 16
United Airlines Logo
2:19 pm - 4:54 am
ECP
-
BOG
14h 35m2 stops
United Airlines Logo
8:30 am - 9:59 pm
BOG
-
ECP
13h 29m1 stop
$601United Airlines
Tue, Feb 24 - Thu, Feb 26
United Airlines Logo
6:30 am - 7:39 pm
ECP
-
BGA
12h 09m2 stops
United Airlines Logo
7:00 am - 12:04 pm
BGA
-
ECP
30h 04m2 stops
$606United Airlines
Booking Insights

KAYAK's insights & trends for Panama City to South America flights

Get data-powered insights and trends into flights from Panama City to South America to help you find the cheapest flights, the best time to fly and much more.

Which airlines fly non-stop between Panama City and South America?

Airline and price data is aggregated from results in KAYAK’s search results from the last 2 weeks for round-trip flights from Panama City to South America.

There is just one airline that flies from Panama City to South America direct and that is Delta. The best round-trip deal found from Delta for the route is to Bogotá (BOG) and costs $482.

Which airlines provide the cheapest flights from Panama City to South America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Panama City to South America were found on American Airlines ($504) and Avianca ($515).

Good to know

Low seasonMarch
Cheapest flight$238
Best time to beat the crowds with an average 5% drop in price.
Most popular time to fly and prices are also 5% lower on average.
Flight from Panama City to Bogotá

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Panama City to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Panama City to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Panama City to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Panama City to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Panama City to South America

 
Need help choosing which airline to fly with from Panama City to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8020 reviews
8.1Boarding
7.9Comfort
7.2Food
8.5Crew
7.8Entertainment
Airline reviews

The only thing nice I can say is the flight crew was really nice and apologetic about the situation. They shared as much information as they had and advised us on what we could do about missing connecting flights. The boarding process was so slow. The gate agent was working by herself and should have had someone working with her. It took almost an hour to board because she was trying to board a full flight of people and provide customer service to everyone who was flying standby and/or had questions. It was really chaotic. This didn't help the fact that we were delayed and folks were missing connections the longer it took.

4.0 OkayLaToya, Dec 2025
MCO - ATL
Read more Delta reviews

The only thing nice I can say is the flight crew was really nice and apologetic about the situation. They shared as much information as they had and advised us on what we could do about missing connecting flights. The boarding process was so slow. The gate agent was working by herself and should have had someone working with her. It took almost an hour to board because she was trying to board a full flight of people and provide customer service to everyone who was flying standby and/or had questions. It was really chaotic. This didn't help the fact that we were delayed and folks were missing connections the longer it took.

The food is terrible. The staff is wonderful. Comfort is good.

I fly Delta all the time, have Platinum Medallion status. But this route seems to have major problems with delays and seems to never leave on time! Have only taken it twice in the last two weeks, and each time it had delays of more than 1 hour... very disappointed!!!!

Getting to the flight was arduous and lengthy. The flight itself was good but the food option wasn’t a good selection. I need to do a Kosher option on my return. Flight crew were nice

We had a lot of really rough weather but that was not Delta's fault. Pilot was amazing.

This flight was straightforward and without difficulty. Service was OK, but I continue to be underwhelmed by level of attention given to Sky Priority passengers.

The ticket agents in West Palm Beach on Friday afternoon Nov. 7th were incredible in getting us on an earlier plane to Atlanta during the government shutdown. Had the taken our original flight we would have missed our connection. She did this on her own, We didn't even have to ask, and she did it all with a smile and showing genuine concern that we would be taken care of. We are very grateful and thankful. We fly often, and now we will be sure to fly Delta.

Non stop on long haul is the way to go. Great experience

The boarding process needs to be refined. Sometimes the gate crew call out the boarding zone, and then flip to the monitor to show which zones are boarding. So unless everyone is gathered around to see the monitor there is usually confusion as wi which zones are boarding.

Passengers need to check in big baggage instead of bringing on the plane. That cause inconvenience for everyone. Otherwise flight was good.

The flights were on time which was great give. It was holiday travel season and there’d been some weather issues. The only complaint and this is every time with United is the terrible seat design. The head rest is not built for comfort and having my neck bent forward for a cross country trip reminded me while I try not to take United flights as a rule.

I’m so sorry, I can’t remember her name, I believe it was Dimpti. She was stellar, also a mature Asian flight attendant, lots of flowers in her hair, just as amazing! But literally the crew was AWESOME . Only downside is there weren’t any charging outlets. Maybe I needed to ask a flight attendant , but it would’ve been nice to have one easily accessible.

The flight was delayed by two de-icings. The seatbelt did not work correctly. It did not stay tight.

Everything was absolutely wonderful from check in to baggage claim. Staff was very professional and sweet. Will definitely recommend United to family and friends.

Aircraft was noisy, old and never dimmed the lights on a night flight even on business class! I flew 17 times on United and probably another 40 on other airlines United USA /Europe flights were the worst to include luggage delayed once going to europe and once coming back

Check how old the airframe is, some older ones have inoperable seat back entertainment or power.

Sitting on the runway after we land for almost two hours! Not sure if we should blame United or Just Dumpy Vance.

Very turbulent trip made it pretty bearable, plus the lack of refreshments served and the lack of any air conditioning before takeoff which took an hour or more.

It was nice to have gotten up upgraded to first class with a meal on a three hour flight

They charged a fee for 1st bag checked. Others in same party were free.

Everything you need to know for your flight to South America

Information on your arrival and departure airports