$646 Find Cheap Flights from Panama City to Ecuador

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to Ecuador departing on 10/3. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

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Cheap Flights from Panama City to Ecuador

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Guayaquil
Guayaquil2 stops$646
Guayaquil
Guayaquil2 stops$646

Book Cheap Panama City to Ecuador Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama City to Ecuador that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to Ecuador

Fri, Oct 3 - Tue, Oct 7
United Airlines Logo
6:30 am - 1:46 pmECP-GYE
31h 16m2 stops
United Airlines Logo
12:15 pm - 9:48 pmGYE-ECP
33h 33m2 stops
$646United Airlines
Find Deal
Fri, Oct 3 - Mon, Oct 6
United Airlines Logo
6:30 am - 11:37 pmECP-GYE
17h 07m2 stops
United Airlines Logo
3:15 am - 9:48 pmGYE-ECP
18h 33m2 stops
$656United Airlines
Find Deal
Fri, Oct 3 - Tue, Oct 7
United Airlines Logo
6:30 am - 1:46 pmECP-GYE
31h 16m2 stops
United Airlines Logo
12:15 pm - 9:52 amGYE-ECP
21h 37m2 stops
$667United Airlines
Find Deal
Fri, Oct 3 - Mon, Oct 6
United Airlines Logo
6:30 am - 1:46 pmECP-GYE
31h 16m2 stops
United Airlines Logo
3:15 am - 9:48 pmGYE-ECP
18h 33m2 stops
$669United Airlines
Find Deal
Sat, Dec 20 - Tue, Jan 20
United Airlines Logo
2:10 pm - 11:18 amECP-GYE
44h 08m2 stops
United Airlines Logo
2:35 pm - 7:52 pmGYE-ECP
30h 17m2 stops
$930United Airlines
Find Deal
Sat, Dec 20 - Mon, Jan 19
 Logo
2:10 pm - 11:18 amECP-GYE
44h 08m2 stops
 Logo
3:30 am - 11:52 amGYE-ECP
33h 22m2 stops
$1,048
Find Deal
Booking Insights

KAYAK's insights & trends for Panama City to Ecuador flights

Get data-powered insights and trends into flights from Panama City to Ecuador to help you find the cheapest flights, the best time to fly and much more.

How long does a flight from Panama City to Ecuador take?

The duration of a flight to Ecuador depends on your arrival airport. The shortest route to Ecuador from Panama City is to Guayaquil, which takes 31h 16m.

Good to know

Cheapest flight$646
Flight from Panama City to Guayaquil

FAQs - booking Ecuador flights

  • How does KAYAK find such low prices on flights from Panama City to Ecuador?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to Ecuador.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to Ecuador?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Panama City to Ecuador is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to Ecuador?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Panama City to Ecuador with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to Ecuador?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Panama City to Ecuador up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Panama City to Ecuador

 
Need help choosing which airline to fly with from Panama City to Ecuador? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 7981 reviews
8.2Boarding
8.5Crew
7.9Entertainment
7.3Food
7.9Comfort
Airline reviews

For a 69 year old with health problems I had the worse experience, no wheelchair when I entered a lady told me to sit and wait while a gentleman told me I had to walk to the Delta station, which I did. I had a carry on and a bag, and I was traveling with my service dog, which was on his carrier and the lady charged me for my carry on luggage, beside all the waiting cause of the delay, I had to walk to get my luggage cause no wheelchair showed up, I am so disappointed. I will get in touch with the company. I got home at 3:00 am, not good for my health situation.

2.0 MediocreRosa, Jul 2025TPA - JFK
Read more Delta reviews

For a 69 year old with health problems I had the worse experience, no wheelchair when I entered a lady told me to sit and wait while a gentleman told me I had to walk to the Delta station, which I did. I had a carry on and a bag, and I was traveling with my service dog, which was on his carrier and the lady charged me for my carry on luggage, beside all the waiting cause of the delay, I had to walk to get my luggage cause no wheelchair showed up, I am so disappointed. I will get in touch with the company. I got home at 3:00 am, not good for my health situation.

Flight was an hour late, who knows why. It was OK, nothing outstanding.

Excellent check-in. Crew was good. Excellent communication from flight deck.

Amazing flight! I have never noticed the uniforms of the attendants before in twenty years of flying except today when one female had the most amazing dress on. It was beautifully designed and showed she was in charge. I never dreamed I would google who designed Delta uniforms . The ultimate compliment is when another woman admires your outfit. . I hope your designer puts it on the market

This had nothing to do with Delta… The flights were on time and flawless. The service was excellent. We purchased seats in (aisle/middle) comfort plus since this was a cross country flight. Unfortunately, the woman seated at the window was 300+ pounds and, as might be expected, covered up about a third of the middle seat also. there was absolutely nothing that Delta could have done about that… I just don’t know what the answer should be. If you purchase a seat, you should should be able to use the entire seat and not just the portion that someone else is not sitting/oozing in. Disappointing…there should be something that could be done….I'm just not sure what solution could be.

The worst part was I was NOT allowed in the lounge even though I was holding a first class ticket and have a premium American Express card. I have flown Business or First Class with many airlines. Delta is the ONLY one who does not extend this courtesy to anyone except people who hold the very expensive American Express card. As a result, I won’t fly Delta if I have any other choice.

The Dekta Rep that checked us in was great. She's very personable, pleasant, and can tell she enjoys her job.

Friendly flight attendants, smooth 8-9 hours flight. Economy seats are small and uncomfortable as usual.

The young man who was our flight attendant in first class was lazy and did not do his job well at all. Never offered drinks upon boarding - actually I take that back... said "are you okay with water" as if I do not want to get you anything else, only passed the snacks around once, got my drink order wrong and then never offered a second round of drinks. He was the worst I have ever seen on Delta and we fly a lot.

Flight left early and arrived early. the whole trip was excellent.

Everything you need to know for your flight from Panama City to Ecuador

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