PTY - BRU

$596 Find Cheap Flights from Panama City to Brussels - Compare and Save

1 adult
1 adult, Economy, 0 bags

Save 21% or more on flights. Compare deals from all over the web.

Never overpay with our price tracking tools.

Filter searches by price, airline and more to find your best flights.

Everything you should know

Cheapest round-trip
$805
Typical prices: $852-$1,110
Air Europa
Tue 11/13Thu 11/22
PTY - BRU • 1 stop
Cheapest one-way
$596
Typical prices: $631-$834
Air Europa
Sun 10/28
PTY - BRU • 1 stop
Nonstop flights
Not available
There are currently no direct flights between Panama City and Brussels Bruxelles-National Airport. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to travel
January
Cheapest • 25% price drop
June
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Istanbul (IST)
Cheapest • Avg $945 (round-trip)
Amsterdam Schiphol (AMS)
Shortest trip • 14h 39m (one-way)
Insights
Insights
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Brussels Bruxelles-National Airport!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Panama City to Bruxelles-National (PTY-BRU)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to Bruxelles-National

Fri, Nov 13 - Sun, Nov 22
Air Europa Logo
9:30 pm - 5:45 pmPTY  Panama City Tocumen Intl-BRU Brussels Bruxelles-National
14h 15m1 stop Madrid Barajas
Air Europa Logo
10:45 am - 7:45 pmBRU  Brussels Bruxelles-National-PTY Panama City Tocumen Intl
15h 00m1 stop Madrid Barajas
$805Air Europa
Mon, Oct 19 - Mon, Oct 26
Air Europa Logo
8:25 pm - 5:40 pmPTY  Panama City Tocumen Intl-BRU Brussels Bruxelles-National
14h 15m1 stop Madrid Barajas
Air Europa Logo
10:45 am - 7:45 pmBRU  Brussels Bruxelles-National-PTY Panama City Tocumen Intl
15h 00m1 stop Madrid Barajas
$809Air Europa
Sat, Oct 17 - Mon, Oct 26
Air Europa Logo
8:25 pm - 5:40 pmPTY  Panama City Tocumen Intl-BRU Brussels Bruxelles-National
14h 15m1 stop Madrid Barajas
Air Europa Logo
10:45 am - 7:45 pmBRU  Brussels Bruxelles-National-PTY Panama City Tocumen Intl
15h 00m1 stop Madrid Barajas
$841Air Europa
Sun, Nov 8 - Sun, Nov 15
Air Europa Logo
9:30 pm - 5:45 pmPTY  Panama City Tocumen Intl-BRU Brussels Bruxelles-National
14h 15m1 stop Madrid Barajas
Air Europa Logo
6:55 pm - 7:45 pmBRU  Brussels Bruxelles-National-PTY Panama City Tocumen Intl
30h 50m1 stop Madrid Barajas
$873Air Europa
Tue, Jan 19 - Tue, Jan 26
Turkish Airlines Logo
10:00 pm - 5:15 pmPTY  Panama City Tocumen Intl-BRU Brussels Bruxelles-National
37h 15m1 stop Istanbul
Turkish Airlines Logo
6:15 pm - 5:10 pmBRU  Brussels Bruxelles-National-PTY Panama City Tocumen Intl
28h 55m2 stops Istanbul Bogotá El Dorado
$876Turkish Airlines
Tue, Jan 19 - Tue, Jan 26
Turkish Airlines Logo
10:00 pm - 10:20 pmPTY  Panama City Tocumen Intl-BRU Brussels Bruxelles-National
18h 20m1 stop Istanbul
Turkish Airlines Logo
3:15 pm - 8:05 pmBRU  Brussels Bruxelles-National-PTY Panama City Tocumen Intl
34h 50m1 stop Istanbul
$876Turkish Airlines
Sat, Oct 17 - Mon, Oct 26
Air Europa Logo
8:25 pm - 5:40 pmPTY  Panama City Tocumen Intl-BRU Brussels Bruxelles-National
14h 15m1 stop Madrid Barajas
Air Europa Logo
6:55 pm - 7:45 pmBRU  Brussels Bruxelles-National-PTY Panama City Tocumen Intl
30h 50m1 stop Madrid Barajas
$884Air Europa
Mon, Oct 12 - Tue, Oct 20
Air Europa Logo
8:25 pm - 5:40 pmPTY  Panama City Tocumen Intl-BRU Brussels Bruxelles-National
14h 15m1 stop Madrid Barajas
Air Europa Logo
10:45 am - 6:40 pmBRU  Brussels Bruxelles-National-PTY Panama City Tocumen Intl
14h 55m1 stop Madrid Barajas
$904Air Europa
Sun, Oct 11 - Tue, Oct 20
Air Europa Logo
8:25 pm - 5:40 pmPTY  Panama City Tocumen Intl-BRU Brussels Bruxelles-National
14h 15m1 stop Madrid Barajas
Air Europa Logo
10:45 am - 6:40 pmBRU  Brussels Bruxelles-National-PTY Panama City Tocumen Intl
14h 55m1 stop Madrid Barajas
$904Air Europa
Sun, Oct 11 - Fri, Oct 16
Air Europa Logo
8:25 pm - 5:40 pmPTY  Panama City Tocumen Intl-BRU Brussels Bruxelles-National
14h 15m1 stop Madrid Barajas
Air Europa Logo
10:45 am - 6:40 pmBRU  Brussels Bruxelles-National-PTY Panama City Tocumen Intl
14h 55m1 stop Madrid Barajas
$904Air Europa
Booking Insights

Price, demand and travel trends for Panama City to Brussels Bruxelles-National Airport flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from Panama City to Brussels Bruxelles-National Airport?

Round-trip flights from Panama City to Brussels Bruxelles-National Airport typically range from $852 to $1,110. The lowest price found in the past 5 days was $805, on Air Europa.

What's the cheapest day of the week to fly from Panama City to Brussels Bruxelles-National Airport?

Based on deals KAYAK users found in the last 12 months, Saturday is the cheapest day of the week to fly from Panama City to Brussels Bruxelles-National Airport. It’s 15% cheaper than the average day, while Tuesday is the most expensive, with prices 9% higher.

What’s the cheapest month to fly from Panama City to Brussels Bruxelles-National Airport?

•January is the cheapest month to fly from Panama City to Brussels Bruxelles-National Airport at $734 round-trip.
•December ($1,185) and April ($1,148) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 61% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

Find deals

Key details for Panama City to Brussels Bruxelles-National Airport flights

Low season

September

Cheapest flight

$596
Beat the crowds with an average 45% drop in travelers.
One-way flight from Panama City to Brussels Bruxelles-National Airport

When to book flights from Panama City to Bruxelles-National

Are your dates flexible? Find out the best times to travel from Panama City to Bruxelles-National based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Panama City to Brussels Bruxelles-National Airport flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from Panama City to Brussels Bruxelles-National Airport?

    Only Economy Class is available on flights from Panama City to Brussels Bruxelles-National Airport.

  • How long is a flight from Panama City to Brussels Bruxelles-National Airport?

    A nonstop flight from Panama City to Brussels Bruxelles-National Airport takes 00m, covering 5,462 miles.

  • Do I need a passport to fly from Panama City to Brussels Bruxelles-National Airport?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • How much should I expect to pay for a Panama City to Brussels Bruxelles-National Airport flight?

    Round-trip flights from Panama City to Brussels Bruxelles-National Airport range from $852 to $1,110, with an average of $977 over the past 12 months. Anything below $852 counts as a good deal.

  • Have flight prices from Panama City to Brussels Bruxelles-National Airport changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $805 to $2,858. That means the highest observed fare was about 4x higher than the lowest one.

  • How are flight prices from Panama City to Brussels Bruxelles-National Airport looking right now?

    One-way fares from Panama City to Brussels Bruxelles-National Airport are currently higher than usual. Average one-way flight prices are about $732, which is 8% above the typical average for this route.

  • What car rental options are available at Brussels Bruxelles-National Airport (BRU)?

    Brussels Bruxelles-National Airport (BRU) hosts 5 major car rental companies, with daily rates starting from around $20 for economy cars. Top options include:

    • Hertz
    • Alamo
    • keddy by Europcar
    • Europcar
    • Sixt

  • Which airports can I use when flying from Panama City to Brussels Bruxelles-National Airport?

    Flights from Panama City to Brussels Bruxelles-National Airport usually depart from Panama City Tocumen Intl (PTY) and arrive at Brussels Bruxelles-National (BRU).

  • Which airports do connecting flights from Panama City to Brussels Bruxelles-National Airport pass through?

    One-stop flights from Panama City to Brussels Bruxelles-National Airport most commonly connect through:

    • Madrid Barajas (MAD) - 62% of one-stop connections
    • Istanbul (IST) - 19% of one-stop connections
    • Amsterdam Schiphol (AMS) - 14% of one-stop connections
    • Newark (EWR) - 3% of one-stop connections

  • Can I save money by using flexible dates for flights from Panama City to Brussels Bruxelles-National Airport?

    Yes. Flexible dates can save you up to 22% on flights from Panama City to Brussels Bruxelles-National Airport. Saturday is the cheapest departure day at $836 round-trip on average, while Tuesday is the most expensive at $1,067, a difference of $231.

    Cheaper weekend fares like these are typical of routes dominated by weekday business travel.

  • How much time can I save by choosing a different layover airport from Panama City to Brussels Bruxelles-National Airport?

    Flying via Amsterdam Schiphol (AMS) gives the shortest average 1-stop total travel time at 14h 39m, compared with 15h 10m via Newark (EWR) and 15h 18m via Washington, D.C. Dulles Intl (IAD).

  • What is the time difference between Panama City and Brussels Bruxelles-National Airport?

    Brussels Bruxelles-National Airport is 7 hours ahead of Panama City (Central European Time vs Eastern Time). Plan for the time shift when scheduling connections or first-day activities.

  • What popular places can I visit in Brussels Bruxelles-National Airport?

    Some of the most popular sights in Brussels Bruxelles-National Airport are Grand Place, King Baudouin Stadium and Brussels Exhibition Centre. These are among the most viewed places in Brussels Bruxelles-National Airport on KAYAK.

Your guide to booking Panama City to Brussels Bruxelles-National Airport flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Saturday departure and avoid flying on Tuesday. On this route, Saturday flights average $836, about $231 less than Tuesday fares (22% savings) based on the last 12 months.
  • If you can choose when to travel, plan your Panama City to Brussels Bruxelles-National Airport trip for January. Fares historically average $734 round-trip in that month - typically $451 less than the most expensive month, which is December (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Brussels Bruxelles-National Airport.

    • NH Brussels Airport
    • Crowne Plaza Brussels Airport By IHG

More options for your flight from Panama City to Bruxelles-National

Complete your trip to Brussels with a hotel stay or car rental

Car rentals in Brussels
Hotels in Brussels
Vacations in Brussels