PTY - BRU

$974 Find Cheap Flights from Panama City to Brussels - Compare and Save

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Everything you should know

Cheapest round-trip
$974
Typical prices: $886-$1,158
Turkish Airlines
Wed 2/28Sun 3/4
PTY - BRU • 1 stop
Cheapest one-way
$980
Typical prices: $653-$834
Iberia
Tue 1/16
PTY - BRU • 2 stops
Nonstop flights
Not available
There are currently no direct flights between Panama City and Brussels Bruxelles-National Airport. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to travel
February
Cheapest • 14% price drop
June
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Istanbul (IST)
Cheapest • Avg $949 (round-trip)
Amsterdam Schiphol (AMS)
Shortest trip • 14h 49m (one-way)
Insights
Insights
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We hope you love your trip to Brussels Bruxelles-National Airport!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Panama City to Bruxelles-National (PTY-BRU)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to Bruxelles-National

Sun, Feb 28 - Thu, Mar 4
Turkish Airlines Logo
6:50 pm - 10:20 pmPTY  Panama City Tocumen Intl-BRU Brussels Bruxelles-National
21h 30m1 stop Istanbul
Turkish Airlines Logo
3:15 pm - 8:05 pmBRU  Brussels Bruxelles-National-PTY Panama City Tocumen Intl
34h 50m1 stop Istanbul
$974Turkish Airlines
Sun, Feb 28 - Thu, Mar 4
Air Europa Logo
9:30 pm - 9:50 amPTY  Panama City Tocumen Intl-BRU Brussels Bruxelles-National
30h 20m1 stop Madrid Barajas
Air Europa Logo
6:55 pm - 7:45 pmBRU  Brussels Bruxelles-National-PTY Panama City Tocumen Intl
30h 50m1 stop Madrid Barajas
$989Air Europa
Sun, Feb 28 - Thu, Mar 4
Turkish Airlines Logo
6:50 pm - 10:20 pmPTY  Panama City Tocumen Intl-BRU Brussels Bruxelles-National
21h 30m1 stop Istanbul
Turkish Airlines Logo
3:15 pm - 8:05 pmBRU  Brussels Bruxelles-National-PTY Panama City Tocumen Intl
34h 50m1 stop Istanbul
$1,005Turkish Airlines
Sun, Feb 28 - Thu, Mar 4
Air Europa Logo
9:30 pm - 9:50 amPTY  Panama City Tocumen Intl-BRU Brussels Bruxelles-National
30h 20m1 stop Madrid Barajas
Air Europa Logo
10:45 am - 7:45 pmBRU  Brussels Bruxelles-National-PTY Panama City Tocumen Intl
15h 00m1 stop Madrid Barajas
$1,016Air Europa
Sun, Mar 14 - Fri, Mar 26
Air Europa Logo
9:30 pm - 9:50 amPTY  Panama City Tocumen Intl-BRU Brussels Bruxelles-National
30h 20m1 stop Madrid Barajas
Air Europa Logo
10:45 am - 7:45 pmBRU  Brussels Bruxelles-National-PTY Panama City Tocumen Intl
15h 00m1 stop Madrid Barajas
$1,036Air Europa
Mon, Mar 8 - Wed, Mar 10
Air Europa Logo
9:30 pm - 5:45 pmPTY  Panama City Tocumen Intl-BRU Brussels Bruxelles-National
14h 15m1 stop Madrid Barajas
Air Europa Logo
6:55 pm - 7:45 pmBRU  Brussels Bruxelles-National-PTY Panama City Tocumen Intl
30h 50m1 stop Madrid Barajas
$1,042Air Europa
Mon, Jan 11 - Mon, Feb 15
United Airlines Logo
4:41 pm - 8:05 amPTY  Panama City Tocumen Intl-BRU Brussels Bruxelles-National
33h 24m2 stops Houston George Bush Intcntl Newark
United Airlines Logo
11:15 am - 8:02 pmBRU  Brussels Bruxelles-National-PTY Panama City Tocumen Intl
14h 47m1 stop Newark
$1,084United Airlines
Mon, Jan 11 - Mon, Feb 15
United Airlines Logo
4:41 pm - 8:05 amPTY  Panama City Tocumen Intl-BRU Brussels Bruxelles-National
33h 24m2 stops Houston George Bush Intcntl Newark
United Airlines Logo
11:15 am - 7:38 pmBRU  Brussels Bruxelles-National-PTY Panama City Tocumen Intl
38h 23m2 stops Newark Houston George Bush Intcntl
$1,084United Airlines
Sun, Mar 14 - Fri, Mar 26
United Airlines Logo
10:55 pm - 8:55 amPTY  Panama City Tocumen Intl-BRU Brussels Bruxelles-National
28h 00m2 stops Newark Chicago O'Hare Intl
United Airlines Logo
11:55 am - 4:10 amBRU  Brussels Bruxelles-National-PTY Panama City Tocumen Intl
22h 15m2 stops Washington, D.C. Dulles Intl Newark
$1,084United Airlines
Sun, Mar 14 - Fri, Mar 26
United Airlines Logo
10:55 pm - 8:05 amPTY  Panama City Tocumen Intl-BRU Brussels Bruxelles-National
27h 10m1 stop Newark
United Airlines Logo
11:55 am - 7:02 pmBRU  Brussels Bruxelles-National-PTY Panama City Tocumen Intl
37h 07m2 stops Washington, D.C. Dulles Intl Newark
$1,084United Airlines
Booking Insights

Price, demand and travel trends for Panama City to Brussels Bruxelles-National Airport flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from Panama City to Brussels Bruxelles-National Airport?

Round-trip flights from Panama City to Brussels Bruxelles-National Airport typically range from $886 to $1,158. The lowest price found in the past 5 days was $974, on Turkish Airlines.

What's the cheapest day of the week to fly from Panama City to Brussels Bruxelles-National Airport?

Based on deals KAYAK users found in the last 12 months, Wednesday is the cheapest day of the week to fly from Panama City to Brussels Bruxelles-National Airport. It’s 13% cheaper than the average day, while Tuesday is the most expensive, with prices 5% higher.

What’s the cheapest month to fly from Panama City to Brussels Bruxelles-National Airport?

•February is the cheapest month to fly from Panama City to Brussels Bruxelles-National Airport at $874 round-trip.
•April ($1,292) and September ($1,200) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 47% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

Find deals

Key details for Panama City to Brussels Bruxelles-National Airport flights

Low season

December

Cheapest flight

$974
Beat the crowds with an average 46% drop in travelers.
The most popular month to fly with an average 92% increase in travelers.
Round-trip flight from Panama City to Brussels Bruxelles-National Airport

When to book flights from Panama City to Bruxelles-National

Are your dates flexible? Find out the best times to travel from Panama City to Bruxelles-National based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Panama City to Brussels Bruxelles-National Airport flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from Panama City to Brussels Bruxelles-National Airport?

    Two cabin classes are available on flights from Panama City to Brussels Bruxelles-National Airport:

    • Economy Class
    • Business Class

  • How long is a flight from Panama City to Brussels Bruxelles-National Airport?

    A nonstop flight from Panama City to Brussels Bruxelles-National Airport takes 00m, covering 5,462 miles.

  • Do I need a passport to fly from Panama City to Brussels Bruxelles-National Airport?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • How much should I expect to pay for a Panama City to Brussels Bruxelles-National Airport flight?

    Round-trip flights from Panama City to Brussels Bruxelles-National Airport range from $886 to $1,158, with an average of $1,013 over the past 12 months. Anything below $886 counts as a good deal.

  • Have flight prices from Panama City to Brussels Bruxelles-National Airport changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $974 to $2,053. That means the highest observed fare was about 2x higher than the lowest one.

  • How are flight prices from Panama City to Brussels Bruxelles-National Airport looking right now?

    One-way fares from Panama City to Brussels Bruxelles-National Airport are currently higher than usual. Average one-way flight prices are about $1,820, which is 163% above the typical average for this route.

  • What car rental options are available at Brussels Bruxelles-National Airport (BRU)?

    Brussels Bruxelles-National Airport (BRU) hosts 5 major car rental companies, with daily rates averaging $48 for economy cars. Top options include:

    • Alamo
    • Hertz
    • keddy by Europcar
    • Europcar
    • Sixt

  • Which airports can I use when flying from Panama City to Brussels Bruxelles-National Airport?

    Flights from Panama City to Brussels Bruxelles-National Airport usually depart from Panama City Tocumen Intl (PTY) and arrive at Brussels Bruxelles-National (BRU).

  • Which airports do connecting flights from Panama City to Brussels Bruxelles-National Airport pass through?

    One-stop flights from Panama City to Brussels Bruxelles-National Airport most commonly connect through:

    • Madrid Barajas (MAD) - 58% of one-stop connections
    • Istanbul (IST) - 21% of one-stop connections
    • Amsterdam Schiphol (AMS) - 15% of one-stop connections
    • Newark (EWR) - 5% of one-stop connections

  • Can I save money by using flexible dates for flights from Panama City to Brussels Bruxelles-National Airport?

    Yes. Flexible dates can save you up to 17% on flights from Panama City to Brussels Bruxelles-National Airport. Wednesday is the cheapest departure day at $886 round-trip on average, while Tuesday is the most expensive at $1,067, a difference of $181.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • How much time can I save by choosing a different layover airport from Panama City to Brussels Bruxelles-National Airport?

    Flying via Amsterdam Schiphol (AMS) gives the shortest average 1-stop total travel time at 14h 49m, compared with 15h 05m via Madrid Barajas (MAD) and 15h 09m via Newark (EWR).

  • What is the time difference between Panama City and Brussels Bruxelles-National Airport?

    Brussels Bruxelles-National Airport is 6 hours ahead of Panama City (Central European Time vs Eastern Time). Plan for the time shift when scheduling connections or first-day activities.

  • What popular places can I visit in Brussels Bruxelles-National Airport?

    Some of the most popular sights in Brussels Bruxelles-National Airport are Grand Place, King Baudouin Stadium and Place Sainte-Catherine. These are among the most viewed places in Brussels Bruxelles-National Airport on KAYAK.

Your guide to booking Panama City to Brussels Bruxelles-National Airport flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Wednesday departure and avoid flying on Tuesday. On this route, Wednesday flights average $886, about $181 less than Tuesday fares (17% savings) based on the last 12 months.
  • If you can choose when to travel, plan your Panama City to Brussels Bruxelles-National Airport trip for February. Fares historically average $874 round-trip in that month - typically $418 less than the most expensive month, which is April (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Brussels Bruxelles-National Airport.

    • NH Brussels Airport
    • Crowne Plaza Brussels Airport By IHG

More options for your flight from Panama City to Bruxelles-National

Complete your trip to Brussels with a hotel stay or car rental

Car rentals in Brussels
Hotels in Brussels
Vacations in Brussels