PTY - CLO

$145 Find Cheap Flights from Panama City to Cali

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to Cali departing on 9/19. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Cali

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Cali, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Cali, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Panama City to Cali (PTY-CLO)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama City to Cali that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to Cali

Fri, Oct 24 - Sun, Nov 9
Copa Airlines Logo
12:43 pm - 2:25 pmPTY-CLO
1h 42mnonstop
Copa Airlines Logo
8:48 am - 10:20 amCLO-PTY
1h 32mnonstop
$267Copa Airlines
Find Deal
Tue, Oct 21 - Tue, Oct 28
Avianca Logo
3:20 am - 8:18 amPTY-CLO
4h 58m1 stop
Avianca Logo
8:55 pm - 1:00 amCLO-PTY
4h 05m1 stop
$273Avianca
Find Deal
Wed, Dec 3 - Wed, Dec 17
Copa Airlines Logo
12:29 pm - 2:11 pmPTY-CLO
1h 42mnonstop
Copa Airlines Logo
3:11 pm - 4:44 pmCLO-PTY
1h 33mnonstop
$288Copa Airlines
Find Deal
Wed, Dec 3 - Thu, Dec 11
Avianca Logo
2:55 am - 7:35 amPTY-CLO
4h 40m1 stop
Avianca Logo
8:55 pm - 1:00 amCLO-PTY
4h 05m1 stop
$293Avianca
Find Deal
Sat, Nov 1 - Tue, Nov 18
Copa Airlines Logo
9:20 am - 11:01 amPTY-CLO
1h 41mnonstop
Copa Airlines Logo
3:12 pm - 4:44 pmCLO-PTY
1h 32mnonstop
$299Copa Airlines
Find Deal
Sun, Oct 19 - Thu, Oct 23
 Logo
9:16 am - 10:54 amPTY-CLO
1h 38mnonstop
 Logo
7:09 pm - 12:10 amCLO-PTY
5h 01m1 stop
Thu, Sep 25 - Mon, Sep 29
 Logo
3:20 am - 7:35 amPTY-CLO
4h 15m1 stop
 Logo
12:01 pm - 1:32 pmCLO-PTY
1h 31mnonstop
Tue, Oct 21 - Tue, Oct 28
 Logo
3:20 am - 10:43 amPTY-CLO
7h 23m1 stop
 Logo
3:12 pm - 4:44 pmCLO-PTY
1h 32mnonstop
Mon, Sep 15 - Tue, Oct 7
Copa Airlines Logo
3:47 pm - 5:25 pmPTY-CLO
1h 38mnonstop
Copa Airlines Logo
12:01 pm - 1:32 pmCLO-PTY
1h 31mnonstop
$318Copa Airlines
Find Deal
Fri, Oct 31 - Tue, Nov 18
Avianca Logo
2:55 am - 7:35 amPTY-CLO
4h 40m1 stop
Avianca Logo
8:55 pm - 1:00 amCLO-PTY
4h 05m1 stop
$320Avianca
Find Deal

Everything you should know

Top airlines
Copa Airlines
Cheapest • from $267 (round-trip)
Copa Airlines
Best reviews • 7.6 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to travel
April
Cheapest • 15% price drop
December
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Cheapest round-trip
$267
Overall average: $210
Copa Airlines
Fri 10/24Sun 11/9
PTY - CLO • Non-stop
Cheapest non-stop
$267
Typical prices: $134-260
Copa Airlines
Fri 10/24Sat 11/8
PTY - CLO • Non-stop
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Cali!
Booking Insights

KAYAK's insights & trends for Panama City to Cali flights

Get data-powered insights and trends into flights from Panama City to Cali to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Panama City to Cali?

The average price of all round-trip flights from Panama City to Cali clicked on KAYAK for each day over the last 12 months.

When flying from Panama City to Cali, you should consider leaving on a Monday and avoid Saturdays if you are looking for the best rates. For your return to Panama City, you’ll find the best rates on Thursdays and the most expensive ones on Tuesdays.

What is the cheapest month to fly from Panama City to Cali?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Panama City to Cali, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Panama City to Cali is April, where tickets cost $188 (return) on average. On the other hand, the most expensive months are July and December, where the average cost of round-trip tickets is $267 and $248 respectively.

Can I save money by flying with a layover from Panama City to Cali?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $278, prices are generally cheapest when you fly direct.

How far in advance should I book a flight from Panama City to Cali?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Panama City to Cali, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Panama City to Cali, you should book around 1 week before departure. For the absolute cheapest price, our data suggests you should book 3 weeks before departure.

Good to know

Low seasonApril
Cheapest flight$145
Best time to beat the crowds with an average 15% drop in price.
Most popular time to fly with an average 12% increase in price.
Flight from Panama City to Cali

When to book flights from Panama City to Cali

Are your dates flexible? Find out the best times to travel from Panama City to Cali based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Panama City to Cali

  • What is the cheapest flight from Panama City to Cali?

    In the last 3 days, the lowest price for a flight from Panama City to Cali was $145 for a one-way ticket and $267 for a round-trip.

  • Do I need a passport to fly between Panama City and Cali?

    Yes, you’ll need a passport to travel to Cali from Panama City.

  • Which aircraft models fly most regularly from Panama City to Cali?

    The Boeing 737-800 is the aircraft model that flies most regularly on the Panama City to Cali flight route.

  • Which airline alliances offer flights from Panama City to Cali?

    Star Alliance, and SkyTeam are the airline alliances operating flights between Panama City and Cali, with Star Alliance being the most commonly used for this route.

  • On which days can I fly direct from Panama City to Cali?

    There are nonstop flights from Panama City to Cali on a daily basis.

  • Which is the best airline for flights from Panama City to Cali, Copa Airlines or Wingo?

    The two airlines most popular with KAYAK users for flights from Panama City to Cali are Copa Airlines and Wingo. With an average price for the route of $266 and an overall rating of 7.6, Copa Airlines is the most popular choice. Wingo is also a great choice for the route, with an average price of $155 and an overall rating of 7.3.

  • How does KAYAK find such low prices on flights from Panama City to Cali?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to Cali.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to Cali?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Cali from Panama City is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to Cali?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Cali with an airline and back to Panama City with another airline. Booking your flights between Panama City and CLO can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to Cali?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Cali from Panama City up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Panama City to Cali

  • Looking for a cheap flight? 25% of our users found flights on this route for $166 or less one-way and $260 or less round-trip.

Prefer to fly direct from Panama City to Cali?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Panama City Tocumen Intl to Cali Alfonso B. Aragon Intl.
Find which airlines fly direct from Panama City Tocumen Intl Airport to Cali Alfonso B. Aragon Intl Airport, which days they fly and book direct flights.

Direct departures

Panama City Tocumen Intl to Cali Alfonso B. Aragon Intl

Monday

Copa Airlines

Copa Airlines

Tuesday

Copa Airlines

Copa Airlines

Wednesday

Copa Airlines

Copa Airlines

Thursday

Copa Airlines

Copa Airlines

Friday

Copa Airlines

Copa Airlines

Saturday

Copa Airlines

Copa Airlines

Sunday

Copa Airlines

Copa Airlines

See more direct flights

Direct returns

Cali Alfonso B. Aragon Intl to Panama City Tocumen Intl

Monday

Copa Airlines

Copa Airlines

Tuesday

Copa Airlines

Copa Airlines

Wednesday

Copa Airlines

Copa Airlines

Thursday

Copa Airlines

Copa Airlines

Friday

Copa Airlines

Copa Airlines

Saturday

Copa Airlines

Copa Airlines

Sunday

Copa Airlines

Copa Airlines

See more direct flights

Reviews of the top 3 airlines serving from Panama City to Cali

 
See real verified KAYAK customer reviews for airlines flying from Panama City to Cali. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to Cali? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.6
Copa AirlinesOverall score based on 1531 reviews
6.8Entertainment
6.8Food
7.4Comfort
8.1Crew
7.8Boarding
Airline reviews

As always, Copa Airlines is great to fly on. The flights are always on time, the staff are pleasant and helpful and it's always a wonderful flying experience.

10.0 ExcellentNeil, Aug 2025PTY - BGI
Read more Copa Airlines reviews

As always, Copa Airlines is great to fly on. The flights are always on time, the staff are pleasant and helpful and it's always a wonderful flying experience.

We had a great flight just wished they had a tv so we can see a movie that would of made my trip excellent.

horrible service, food was an embarrassment, no charging for cellphones, stay away

Great experience with a crew always thinking in the passenger

I selected first class expecting excetional service. It was mediocre at best. The food service was cold, meal choices was poor and on one leg they did provide dessert. I did enjoy the lay day seat but the movies were old and nothing current. Boarding the plane is always hot. So boarding is quite warm until your in the air. I took a small personal air fan. Update the meals and movies.

Did upgrade, travel in business it was great (more room I could sleep)

Had to go through security at the gate again. Had to take off shoes and go through the whole thing again even though we have global entry. They asked us to check in items bought at duty free during our layover and since we checked our luggage at the original departure airport, they forced us to check in a small backpack. None of this ever happened with other airlines. In addition, no vegetarian food option and no snacks during a 7 hr flight. Luggage limits are unusually small. This is unacceptable. Will NEVER fly Copa again and will tell friends and family to avoid this airline.

We paid extra with copa for seats near one another The plane was changed and we lost our seats We were all Separated. We have not received a refund for our seats despite emailing and calling.

It was ok. However, the food was quite poor since I don't eat pasta.

Tell people to remain in their seats during the meal/beverage distribution. Enforce boarding by group numbers. No one was checking. Tell people to turn their electronics speakers off. Bigger cups for drinks.

Delay at the airport was not clearly communicated. No announcements were made and since we are foreigners it was very hard to know what was happening at the Wingo gate.

That they were on tike but, They charge again for baggage while we already paid when we buy our tickets

Perfect for a very low cost flight. In time, safety perfect, and of course no service, just what you effectivement !

Delayed three hours and they knew it but didn’t say anything upon checking in

Cumple con su función, transportar, no incluye comida a menos que se pague un valor adicional y así mismo con los asientos y demás, brindan precios económicos pero tratan de compensarlo cobrando por todo lo demás, si desean un viaje económico y que no dure más de 3 horas el vuelo, recomendando

i was seated apart from my girlfriend even though I bought the tickets at the same time and the flight was half full. what are some of these airlines thinking when they assign seats?

Wingo changed departure time 3 times and kept us moving from one gate to a different one. A 1 one flight took me more than 8 hours. Don't fly wit Wingo, the worst experience ever

Nothing the vendor services and overall process was not an experience I would ever want to revisit again .

Pros: "Crew was great and friendly- good meals on long flights- best airline!"
Cons: "everything was great"

Usb plugs for charging your phone does not work in every flight. uncomfortable chairs even in higher categories.

Luggage lost and nowhere to be found, no response from either airline regarding my bag

The usb plugs for charging your phone didn’t work, the seats were coarse and hard. Not very comfortable. No inflight WiFi

The seats were uncomfortable and barely reclined at all. Very little leg room despite being business class. The crew was friendly and the food was good. Had to use my own phone for in-flight entertainment.

Very uncomfortable planes , poor service on the plane , take your own water so you don’t dehydrate , in a 6 hs flight they sold one time food and beverage . 1 plane was delayed 6 hs , I lost a connecting flight . Then in the way back they announce a delay of 2 hs so I had to take a different flight to arrive on time for my connecting flight . Avoid this airline .

Boarding was excessively slow. They do it by groups in a way that it doesn’t make sense. After business class , ppl that need assistance and any other priority group they should have ppl board from the back to the front. First rows 20+. Then 15+. Then 10, etc. having ppl sitting in the back board last makes no sense. The libe backame long as soon as ppl on rows 10 or so where told to board. The line went all the way up the ramp and tunnel for 25 mins.

Seats are very tight even in Plus, no complimentary snacks or beverage

The chicken that was served in business class was cold!

Flight to Bogotá delayed by 3 h Missed connection from Bogotá to Guayaquil. Avianca unable to bring us to Baltra on time Overall delay 36h. We missed boat departure from galagos. Overall 10 day trip needed to be cancelled. Avianca was completely un-professional.

Late departure. When the flight arrived in Medellin the plane sat at the gate for 20 minutes waiting for a bus for us to get off the plane.

Everything you need to know for your flight from Panama City to Cali

Information on your arrival and departure airports

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