$211 Find Cheap Flights from Cali to Panama City - Compare and Save

These are the earliest and latest flight times available from Cali to Panama City:

• Earliest: departs at 4:38 am and lands at 6:15 am
• Latest: departs at 6:38 pm and lands at 8:15 pm.

The flight takes about 1h 37m.

Two cabin classes are available on flights from Cali to Panama City:

• Economy Class
• Business Class

A nonstop flight from Cali to Panama City takes 1h 37m, covering 434 miles.

Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

Round-trip flights from Cali to Panama City range from $275 to $372, with an average of $313 over the past 12 months. Anything below $275 counts as a good deal.

Last-minute fares on this route (booked within two weeks of departure) run 7% above the $313 route average. Book 6 weeks before departure for the lowest fares.

On this route, nonstop and layover fares are close on average, with nonstop at $314 round-trip and layover options via Bogotá El Dorado (BOG) at $317.

Copa Airlines is the only airline operating Cali to Panama City flights. 97% of its flights are on time.

There is no standard. Checked-bag policies vary by airline on this route. Most carriers charge $69–$100 for the first checked bag in economy. Premium fares and elite-status bookings typically include a free checked bag.

The Boeing 737-800 family is used most often on this route, operated mainly by Copa Airlines and Wingo. Other aircraft seen on the route include Airbus A320-100/200 variants.

Afternoon is the busiest departure period on Cali to Panama City flights, with 40% of flights leaving in that window. Morning departures account for 20%, evening flights for 20%, and night flights for 20%.

Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $364 to $1,130. That means the highest observed fare was about 3x higher than the lowest one.

One-way fares from Cali to Panama City are currently higher than usual. Average one-way flight prices are about $311, which is 61% above the typical average for this route.

Panama City Tocumen Intl Airport (PTY) hosts 5 major car rental companies, with daily rates starting from around $1 for economy cars. Top options include:

• Avis
• Europcar
• Ace
• Budget
• Hertz

Flights from Cali to Panama City usually depart from Cali Alfonso B. Aragon Intl (CLO) and arrive at Panama City Tocumen Intl (PTY).

Morning flights have the fewest delays on this route, while evening departures tend to have the most.

A flight is considered delayed when it departs 15 minutes or more after its scheduled time. This is the standard used by the US Department of Transportation and most airline industry reporting. On the Cali to Panama City route, 3% of flights were delayed in the past 3 months, with delays averaging 1h 39m.

One-stop flights from Cali to Panama City most commonly connect through:

• Bogotá El Dorado (BOG) - 99% of one-stop connections
• Medellín Jose Maria Cordova Intl (MDE) - 0% of one-stop connections
• Mexico City Benito Juarez (MEX) - 0% of one-stop connections

Yes. Flexible dates can save you up to 6% on flights from Cali to Panama City. Tuesday is the cheapest departure day at $308 round-trip on average, while Sunday is the most expensive at $326, a difference of $18.

KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

Only Copa Airlines operates flights between Cali and Panama City.

Flying via Bogotá El Dorado (BOG) gives the shortest average 1-stop total travel time at 4h 34m, compared with 12h 43m via Medellín Jose Maria Cordova Intl (MDE) and 28h 42m via Mexico City Benito Juarez (MEX).

Some of the most popular sights in Panama City are ATLAPA Conventions Center, Panama Old Cathedral and Veneto Casino. These are among the most viewed places in Panama City on KAYAK.

Among airlines operating Cali to Panama City flights:

• Copa Airlines: offers free seat selection

Extra legroom and free seat selection availability depends on fare class and route.

Here are some options for this route, based on selected ticket types and cabin classes:

• Copa Airlines: a cabin bag and a checked bag in Economy Class

Bag allowance can vary by ticket type, cabin class, route and airline, so always check the fare details before booking.