CLO - PTY

$150 Find Cheap Flights from Cali to Panama City

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Cali to Panama City departing on 2/21. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Panama City

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Cali to Panama City, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Cali to Panama City, as well as popular online travel agencies
Travelers love KAYAK
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Everything you should know

Cheapest round-trip
$258
Overall average: $193
Copa Airlines
Fri 2/13Mon 2/16
CLO - PTY • Non-stop
Cheapest one-way
$150
Typical prices: $135-$171
Copa Airlines
Sat 2/21
CLO - PTY • Non-stop
Our travelers' advice
AI-powered summary based on content written by travel experts. AI can make mistakes.
Copa's Economy Extra seats offer more space.
United's Economy Plus seats provide extra legroom.
Expert advice
Expert advice
Expert advice
Expert advice
Top airlines
Copa Airlines
Cheapest • from $258 (round-trip)
Copa Airlines
Best reviews • 7.5 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to book
7 weeks
in advance
Our data shows that travelers who book at least 7 weeks in advance save around 18% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
March
Cheapest • 17% price drop
February
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Panama City!
Flight Deals
Booking Insights
Expert advice
Flight Deals

Cheap Flights from Cali to Panama City (CLO-PTY)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Cali to Panama City that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Cali to Panama City

Fri, Feb 13 - Mon, Feb 16
Copa Airlines Logo
5:03 am - 6:34 am
CLO
-
PTY
1h 31mnonstop
Copa Airlines Logo
12:29 pm - 2:10 pm
PTY
-
CLO
1h 41mnonstop
$258Copa Airlines
Sat, Mar 28 - Thu, Apr 2
Copa Airlines Logo
8:48 am - 10:20 am
CLO
-
PTY
1h 32mnonstop
Copa Airlines Logo
9:25 am - 11:06 am
PTY
-
CLO
1h 41mnonstop
$263Copa Airlines
Thu, Apr 16 - Mon, Apr 20
Copa Airlines Logo
5:00 am - 6:34 am
CLO
-
PTY
1h 34mnonstop
Copa Airlines Logo
9:25 am - 11:06 am
PTY
-
CLO
1h 41mnonstop
$269Copa Airlines
Sat, Feb 28 - Sat, Mar 7
Avianca Logo
8:55 pm - 1:00 am
CLO
-
PTY
4h 05m
1 stop
Avianca Logo
5:50 pm - 10:35 pm
PTY
-
CLO
4h 45m
1 stop
$273Avianca
Thu, Feb 12 - Sat, Feb 14
Avianca Logo
8:40 pm - 1:00 am
CLO
-
PTY
4h 20m
1 stop
Avianca Logo
2:55 am - 7:35 am
PTY
-
CLO
4h 40m
1 stop
$274Avianca
Tue, Mar 31 - Sat, Apr 11
Avianca Logo
8:45 pm - 1:05 am
CLO
-
PTY
4h 20m
1 stop
Avianca Logo
10:10 am - 2:10 pm
PTY
-
CLO
4h 00m
1 stop
$275Avianca
Thu, Feb 12 - Tue, May 12
Copa Airlines Logo
5:03 am - 6:34 am
CLO
-
PTY
1h 31mnonstop
Copa Airlines Logo
3:55 pm - 5:36 pm
PTY
-
CLO
1h 41mnonstop
$290Copa Airlines
Fri, Feb 13 - Mon, Feb 16
Avianca Logo
6:45 pm - 12:40 am
CLO
-
PTY
5h 55m
1 stop
Avianca Logo
2:55 pm - 7:55 pm
PTY
-
CLO
5h 00m
1 stop
$291Avianca
Tue, Apr 28 - Sat, May 2
Copa Airlines Logo
12:06 pm - 1:40 pm
CLO
-
PTY
1h 34mnonstop
Copa Airlines Logo
9:25 am - 11:06 am
PTY
-
CLO
1h 41mnonstop
$295Copa Airlines
Thu, Apr 2 - Mon, Apr 6
Copa Airlines Logo
3:10 pm - 4:44 pm
CLO
-
PTY
1h 34mnonstop
Copa Airlines Logo
9:55 pm - 11:36 pm
PTY
-
CLO
1h 41mnonstop
$306Copa Airlines
Booking Insights

KAYAK's insights & trends for Cali to Panama City flights

Get data-powered insights and trends into flights from Cali to Panama City to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Cali to Panama City?

The average price of all round-trip flights from Cali to Panama City clicked on KAYAK for each day over the last 12 months.

Your flight ticket price will generally be cheaper if you fly to Panama City on a Thursday and more expensive on a Saturday. On your return trip to Cali, you should consider flying back on a Saturday, and avoid Tuesdays for better deals.

What is the cheapest month to fly from Cali to Panama City?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Cali to Panama City, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Cali to Panama City is March, where tickets cost $178 (return) on average. On the other hand, the most expensive months are December and January, where the average cost of round-trip tickets is $276 and $251 respectively.

Can I save money by flying with a layover from Cali to Panama City?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $298, prices are generally cheapest when you fly direct.

How far in advance should I book a flight from Cali to Panama City?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Cali to Panama City, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Cali to Panama City, you should book around 7 weeks before departure, which saves you about 18% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 22 weeks before departure.

Expert advice

Expert advice for your flight from Cali to Panama City

 
AI-powered summary based on content written by travel experts. AI can make mistakes.
KAYAK teamed up with top travel experts to share the best tips for your journey.
Our travel experts
Stefanie Waldek

Stefanie Waldek

Expert on United Airlines

Stefanie Waldek is a freelance space, travel, and design writer based in Saratoga Springs, NY. Her words have appeared in Space.com, Travel + Leisure, Condé Nast Traveler, Architectural Digest, and House Beautiful, among other publications. An expert in aviation and expedition cruising, Stefanie is frequently up in the air or on the sea, likely en route to Antarctica or the Arctic.

Ramsey Qubein

Ramsey Qubein

Expert on Copa Airlines

An avid traveler and aviation expert who has visited 173 countries, all 50 states and seven continents, Ramsey Qubein flies nearly 400,000 miles a year. As a North Carolina-based freelance journalist for publications including Conde Nast Traveler, Forbes, USA Today and Bloomberg among others, he explores the latest trends in aviation, hospitality, cruises and business.

Good to know

Low seasonMay
Cheapest flight$150
Best time to beat the crowds with an average 8% drop in price.
Most popular time to fly and prices are also 10% lower on average.
Flight from Cali to Panama City

When to book flights from Cali to Panama City

Are your dates flexible? Find out the best times to travel from Cali to Panama City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Cali to Panama City

  • What is the cheapest flight from Cali to Panama City?

    In the last 3 days, the lowest price for a flight from Cali to Panama City was $150 for a one-way ticket and $258 for a round-trip.

  • Do I need a passport to fly between Cali and Panama City?

    A passport is required to fly from Cali to Panama City.

  • Which airports will I be using when flying from Cali to Panama City?

    Cali airport is called Cali Alfonso B. Aragon Intl and the only airport in Panama City is Panama City Tocumen Intl.

  • Which airlines offer Wi-Fi service onboard planes from Cali to Panama City?

    American Airlines, Delta, and JetBlue offer inflight Wi-Fi service on the Cali to Panama City flight route.

  • Which aircraft models fly most regularly from Cali to Panama City?

    The Boeing 737-800 is the aircraft model that flies most regularly on the Cali to Panama City flight route.

  • Which airline alliances offer flights from Cali to Panama City?

    Star Alliance is the only airline alliance operating flights between Cali and Panama City.

  • On which days can I fly direct from Cali to Panama City?

    There are nonstop flights from Cali to Panama City on a daily basis.

  • Which is the best airline for flights from Cali to Panama City, Copa Airlines or Wingo?

    The two airlines most popular with KAYAK users for flights from Cali to Panama City are Copa Airlines and Wingo. With an average price for the route of $287 and an overall rating of 7.6, Copa Airlines is the most popular choice. Wingo is also a great choice for the route, with an average price of $186 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from Cali to Panama City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Cali to Panama City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Cali to Panama City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Panama City from Cali is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Cali to Panama City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Panama City with an airline and back to Cali with another airline. Booking your flights between Cali and PTY can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Cali to Panama City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Panama City from Cali up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Cali to Panama City

  • Looking for a cheap flight? 25% of our users found flights on this route for $287 or less one-way and $370 or less round-trip.

Prefer to fly direct from Cali to Panama City?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Cali Alfonso B. Aragon Intl to Panama City Tocumen Intl.
Find which airlines fly direct from Cali Alfonso B. Aragon Intl Airport to Panama City Tocumen Intl Airport, which days they fly and book direct flights.

Direct departures

Cali Alfonso B. Aragon Intl to Panama City Tocumen Intl

Monday

Copa Airlines

Copa Airlines

Tuesday

Copa Airlines

Copa Airlines

Wednesday

Copa Airlines

Copa Airlines

Thursday

Copa Airlines

Copa Airlines

Friday

Copa Airlines

Copa Airlines

Saturday

Copa Airlines

Copa Airlines

Sunday

Copa Airlines

Copa Airlines

See more direct flights

Direct returns

Panama City Tocumen Intl to Cali Alfonso B. Aragon Intl

Monday

Copa Airlines

Copa Airlines

Tuesday

Copa Airlines

Copa Airlines

Wednesday

Copa Airlines

Copa Airlines

Thursday

Copa Airlines

Copa Airlines

Friday

Copa Airlines

Copa Airlines

Saturday

Copa Airlines

Copa Airlines

Sunday

Copa Airlines

Copa Airlines

See more direct flights

Reviews of the top 3 airlines serving from Cali to Panama City

 
See real verified KAYAK customer reviews for airlines flying from Cali to Panama City. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Cali to Panama City? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
Copa AirlinesOverall score based on 1559 reviews
6.8Entertainment
7.8Boarding
6.8Food
8.1Crew
7.4Comfort
Airline reviews

Seats were awful. Media should have been included for such a long flight.

4.0 OkayPaul, Jan 2026
LIM - PTY
Read more Copa Airlines reviews

Seats were awful. Media should have been included for such a long flight.

There should be a warning regarding the quality of the aircraft on the website as we reserve the tickets. There was no TV or any type of screen onboard. The wifi they offer is good for nothing. Traveling 9 hours straight with kids and no type of entetainment was horrible. I wish I had been informed prior so I could buy a ticket with another airline. The food was a joke too. A very tiny portion per passenger. They also charged $100 per checked bag. With United I used to pay $60. So, fair to say that I wont be flying Copa anymore. Their aircraft was super old, outdated, no entertainment, with nearly no onboard food.

I always enjoy flying Copa. There are very few airlines where I can enjoy a comfortable sleep in-flight. The snacks weren't the best, but they sufficed. The in-flight entertainment was fantastic, and I crossed another movie off my watch list.

Very strict carry on rules meant most of the plane had to gate check their luggage. As is often the case had things that were broken because of this, but I appreciated not being charged to gate check. Otherwise good flight and great crew once on the plane

Simply as follows:- First, there was no vegetarian option for the meal Second, only 2 washrooms for the entire economy class.

I liked the meatloaf the chicken was awful but the plane was on time and got there and the staff was nice.

They were super friendly bumped me up to exit row free of charge, All flight legs were on time

Boarding was quick & efficient; they gave boarding groups due priority; staff & air crew were very cordial and helpful, pleasant flight.

Cops Airlines is fantastic! The level of care and professionalism provided by the entire crew was top rate.

the food served was an embarrassment. No connection for charging the cellphone... What a crappy airline.

Delay at the airport was not clearly communicated. No announcements were made and since we are foreigners it was very hard to know what was happening at the Wingo gate.

That they were on tike but, They charge again for baggage while we already paid when we buy our tickets

Perfect for a very low cost flight. In time, safety perfect, and of course no service, just what you effectivement !

Delayed three hours and they knew it but didn’t say anything upon checking in

Cumple con su función, transportar, no incluye comida a menos que se pague un valor adicional y así mismo con los asientos y demás, brindan precios económicos pero tratan de compensarlo cobrando por todo lo demás, si desean un viaje económico y que no dure más de 3 horas el vuelo, recomendando

i was seated apart from my girlfriend even though I bought the tickets at the same time and the flight was half full. what are some of these airlines thinking when they assign seats?

Wingo changed departure time 3 times and kept us moving from one gate to a different one. A 1 one flight took me more than 8 hours. Don't fly wit Wingo, the worst experience ever

Nothing the vendor services and overall process was not an experience I would ever want to revisit again .

Pros: "Crew was great and friendly- good meals on long flights- best airline!"
Cons: "everything was great"

Horrible experience with Avianca, they delayed their flight and when we arrived to NYC, AVIANCA took 1 hr y 30 mins to park the airplane and all passenger get off the plane, it made me lost all my trains to get back home and I came back to my place at 3 am instead of 12 am. On the top of that their plane seat are so uncomfortable and is not enough space and killed my legs and knees, Avianca used to be good when it was a Colombian company, now after Brasilian company bought them, their service quality is bad and their flights are delayed and oversold.

It was delayed and I lost my connection flight to Cali and I missed my Mom's funeral and avianca lost my check in luggage

I upgraded to businesses class. Because of that the flight was comfortable.

Avianca has transitioned from full service legacy airline to "low cost" but has now became a strange hybrid (minimum leg space, started offering business class in domestic flights again, charges passenger for printing boarding pass, etc.). National and international coverage and destinations are really wide but service is not at its best

Provide free food and drinks on an international flight. Add updated head rests

Not good, tried to purchase a first class upgrade and they couldn’t get it done. Was super uncomfortable the whole time.

Boarding was late due to the company’s that cleaned the aircraft (very poorly done) and the catering company. The entertainment system was not working for this six hour flight, uncomfortable seats in business (barely any cushion or recline). The airline staff is very good but the planes are horrible and not well maintained.

I like the crew members they're very friendly. Clean plane. The flight was on time. I dont like the comfort my car seat its better that the plane seats. They charge for everything. This airline was very good. Now it's a low cost airline

No free snacks nor drinks on very short 30min flight. Entertainment system is over wifi to your own phone or tablet, which is good but often a show or movie just stops and refuses to continue

6 hour flight and have to pay for everything 100 dollars to add a carry-on bag is insane

Everything you need to know for your flight from Cali to Panama City

Information on your arrival and departure airports