PTY - GYE

$177 Find Cheap Flights from Panama City to Guayaquil

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to Guayaquil departing on 4/20. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Guayaquil

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Guayaquil, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Guayaquil, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$268
Typical prices: $296-$394
Avianca
Fri 2/27Mon 3/2
PTY - GYE • 1 stop
Cheapest non-stop
$282
Typical prices: $300-$374
Copa Airlines
Fri 2/27Mon 3/2
PTY - GYE • Non-stop
Top airlines
Avianca
Cheapest • from $268 (round-trip)
Copa Airlines
Best reviews • 7.5 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to book
4 weeks
in advance
Our data shows that travelers who book at least 4 weeks in advance save around 8% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
May
Cheapest • 14% price drop
December
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Guayaquil!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Panama City to Guayaquil (PTY-GYE)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama City to Guayaquil that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to Guayaquil

Fri, Feb 27 - Mon, Mar 2
Avianca Logo
2:55 pm - 11:35 pm
PTY
-
GYE
8h 40m
1 stop
Avianca Logo
3:35 pm - 12:40 am
GYE
-
PTY
9h 05m
1 stop
$268Avianca
Thu, Feb 26 - Mon, Mar 2
Avianca Logo
2:55 am - 11:25 am
PTY
-
GYE
8h 30m
2 stops
Avianca Logo
10:25 am - 4:55 pm
GYE
-
PTY
6h 30m
1 stop
$270Avianca
Fri, Feb 27 - Mon, Mar 2
Copa Airlines Logo
9:40 pm - 11:55 pm
PTY
-
GYE
2h 15mnonstop
Copa Airlines Logo
6:31 pm - 8:41 pm
GYE
-
PTY
2h 10mnonstop
$282Copa Airlines
Tue, Mar 10 - Sat, Mar 21
Copa Airlines Logo
9:02 am - 11:18 am
PTY
-
GYE
2h 16mnonstop
Copa Airlines Logo
4:33 am - 6:43 am
GYE
-
PTY
2h 10mnonstop
$311Copa Airlines
Fri, Feb 27 - Mon, Mar 2
Multiple Airlines Logo
5:50 pm - 11:35 pm
PTY
-
GYE
5h 45m
1 stop
Multiple Airlines Logo
6:31 pm - 8:41 pm
GYE
-
PTY
2h 10mnonstop
$336Multiple Airlines
Wed, Apr 22 - Tue, Apr 28
Copa Airlines Logo
11:21 am - 1:35 pm
PTY
-
GYE
2h 14mnonstop
Copa Airlines Logo
12:22 pm - 2:34 pm
GYE
-
PTY
2h 12mnonstop
$342Copa Airlines
Mon, Jul 6 - Mon, Jul 20
Avianca Logo
3:05 am - 11:20 am
PTY
-
GYE
8h 15m
2 stops
Avianca Logo
3:30 am - 9:15 am
GYE
-
PTY
5h 45m
1 stop
$362Avianca
Sat, Feb 28 - Sat, Mar 7
Avianca Logo
2:55 am - 12:30 pm
PTY
-
GYE
9h 35m
2 stops
Avianca Logo
9:05 am - 2:00 pm
GYE
-
PTY
4h 55m
1 stop
$368Avianca
Tue, Jul 14 - Tue, Aug 25
Copa Airlines Logo
6:39 pm - 8:53 pm
PTY
-
GYE
2h 14mnonstop
Copa Airlines Logo
4:29 am - 6:41 am
GYE
-
PTY
2h 12mnonstop
$375Copa Airlines
Sun, Mar 1 - Sat, Mar 7
Multiple Airlines Logo
9:02 am - 11:18 am
PTY
-
GYE
2h 16mnonstop
Multiple Airlines Logo
6:55 pm - 1:00 am
GYE
-
PTY
6h 05m
1 stop
$394Multiple Airlines
Booking Insights

KAYAK's insights & trends for Panama City to Guayaquil flights

Get data-powered insights and trends into flights from Panama City to Guayaquil to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Panama City to Guayaquil?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Panama City to Guayaquil departing in February.

What’s the cheapest day of the week to fly from Panama City to Guayaquil?

The average price of all round-trip flights from Panama City to Guayaquil clicked on KAYAK for each day over the last 12 months.

When flying from Panama City to Guayaquil, you should consider leaving on a Wednesday and avoid Fridays if you are looking for the best rates. For your return to Panama City, you’ll find the best rates on Fridays and the most expensive ones on Sundays.

What is the cheapest month to fly from Panama City to Guayaquil?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Panama City to Guayaquil, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Panama City to Guayaquil is May, where tickets cost $283 (return) on average. On the other hand, the most expensive months are March and January, where the average cost of round-trip tickets is $358 and $347 respectively.

Can I save money by flying with a layover from Panama City to Guayaquil?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $257, prices are generally cheapest when you fly direct.

How far in advance should I book a flight from Panama City to Guayaquil?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Panama City to Guayaquil, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Panama City to Guayaquil, you should book around 4 weeks before departure, which saves you about 8% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 22 weeks before departure.

Good to know

Low seasonFebruary
Cheapest flight$177
Best time to beat the crowds but there is an average 5% increase in price.
Most popular time to fly with an average 5% increase in price.
Flight from Panama City to Guayaquil

When to book flights from Panama City to Guayaquil

Are your dates flexible? Find out the best times to travel from Panama City to Guayaquil based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Panama City to Guayaquil

  • What is the cheapest flight from Panama City to Guayaquil?

    In the last 3 days, the lowest price for a flight from Panama City to Guayaquil was $177 for a one-way ticket and $268 for a round-trip.

  • Do I need a passport to fly between Panama City and Guayaquil?

    Yes

  • Which aircraft models fly most regularly from Panama City to Guayaquil?

    The Boeing 737 MAX 9 is the aircraft model that flies most regularly on the Panama City to Guayaquil flight route.

  • Which airline alliances offer flights from Panama City to Guayaquil?

    Star Alliance is the only airline alliance operating flights between Panama City and Guayaquil.

  • On which days can I fly direct from Panama City to Guayaquil?

    There are nonstop flights from Panama City to Guayaquil on a daily basis.

  • Which is the best airline for flights from Panama City to Guayaquil, Copa Airlines or Avianca?

    The two airlines most popular with KAYAK users for flights from Panama City to Guayaquil are Copa Airlines and Avianca. With an average price for the route of $347 and an overall rating of 7.5, Copa Airlines is the most popular choice. Avianca is also a great choice for the route, with an average price of $355 and an overall rating of 6.5.

  • How does KAYAK find such low prices on flights from Panama City to Guayaquil?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to Guayaquil.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to Guayaquil?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Guayaquil from Panama City is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to Guayaquil?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Guayaquil with an airline and back to Panama City with another airline. Booking your flights between Panama City and GYE can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to Guayaquil?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Guayaquil from Panama City up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Panama City to Guayaquil

  • Looking for a cheap flight? 25% of our users found flights on this route for $202 or less one-way and $257 or less round-trip.

Prefer to fly direct from Panama City to Guayaquil?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Panama City Tocumen Intl to Guayaquil Jose Joaquin de Olmedo.
Find which airlines fly direct from Panama City Tocumen Intl Airport to Guayaquil Jose Joaquin de Olmedo Airport, which days they fly and book direct flights.

Direct departures

Panama City Tocumen Intl to Guayaquil Jose Joaquin de Olmedo

Monday

Copa Airlines

Copa Airlines

Tuesday

Copa Airlines

Copa Airlines

Wednesday

Copa Airlines

Copa Airlines

Thursday

Copa Airlines

Copa Airlines

Friday

Copa Airlines

Copa Airlines

Saturday

Copa Airlines

Copa Airlines

Sunday

Copa Airlines

Copa Airlines

See more direct flights

Direct returns

Guayaquil Jose Joaquin de Olmedo to Panama City Tocumen Intl

Monday

Copa Airlines

Copa Airlines

Tuesday

Copa Airlines

Copa Airlines

Wednesday

Copa Airlines

Copa Airlines

Thursday

Copa Airlines

Copa Airlines

Friday

Copa Airlines

Copa Airlines

Saturday

Copa Airlines

Copa Airlines

Sunday

Copa Airlines

Copa Airlines

See more direct flights

Reviews of the top airlines flying from Panama City to Guayaquil

 
See real verified KAYAK customer reviews for airlines flying from Panama City to Guayaquil. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to Guayaquil? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
Copa AirlinesOverall score based on 1559 reviews
6.8Entertainment
7.4Comfort
6.8Food
7.8Boarding
8.1Crew
Airline reviews

Copa staff at PTY and one particular crew member were unhelpful & rude.

6.0 GoodOluwaseyi, Feb 2026
PTY - POS
Read more Copa Airlines reviews

Copa staff at PTY and one particular crew member were unhelpful & rude.

A lot things happened in this trip.The fly should be less stress.

Horrible. No TV or any type of entertainment on board. Passwnger listening to/watching stuff on their own phone with no headphones making it noise and uncomfortable for everyone else, little/tiny food portions, old seats, useless wifi (cant access anything). Horrible exlerience especially it was a lomg distance flight with kids.

The flight was good overall. Everything went smoothly, although the landing was a bit rough. Still, it was a pleasant experience

Some of the Air hostesses are not that friendly. Need improvement

I liked the meatloaf the chicken was awful but the plane was on time and got there and the staff was nice.

As always, Copa Airlines is great to fly on. The flights are always on time, the staff are pleasant and helpful and it's always a wonderful flying experience.

We had a great flight just wished they had a tv so we can see a movie that would of made my trip excellent.

horrible service, food was an embarrassment, no charging for cellphones, stay away

Great experience with a crew always thinking in the passenger

Horrible experience with Avianca, they delayed their flight and when we arrived to NYC, AVIANCA took 1 hr y 30 mins to park the airplane and all passenger get off the plane, it made me lost all my trains to get back home and I came back to my place at 3 am instead of 12 am. On the top of that their plane seat are so uncomfortable and is not enough space and killed my legs and knees, Avianca used to be good when it was a Colombian company, now after Brasilian company bought them, their service quality is bad and their flights are delayed and oversold.

It was delayed and I lost my connection flight to Cali and I missed my Mom's funeral and avianca lost my check in luggage

I upgraded to businesses class. Because of that the flight was comfortable.

We found the chairs to be really uncomfortable. It’s also really unacceptable that no form of food or drink is included in a 6+ hour flight

Not good, tried to purchase a first class upgrade and they couldn’t get it done. Was super uncomfortable the whole time.

Boarding was late due to the company’s that cleaned the aircraft (very poorly done) and the catering company. The entertainment system was not working for this six hour flight, uncomfortable seats in business (barely any cushion or recline). The airline staff is very good but the planes are horrible and not well maintained.

Staff are the rudest in the industry … awful customer service … will never fly Avianca again

Pros: we leave and arrive on time Cons: the most uncomfortable seats ever. You cant recline at all your seats. No entertainment No TVs flight attendants didn't provide even a glass of water. You have to go to back of the airplane and ask for one. I am Colombian and I remember seeing the flight attendants very neat, elegants which is or was a staple of Avianca.it was one with tennis shoes, no male up, the hair was messy... that was really odd.

The flight attendant smashed her beverage cart into my knee, causing significant amount of pain. The seats were extremely uncomfortable. No food or drink is offered unless you want to pay the ridiculous prices for it. The schedule of flying in the overnight hours is also very uncomfortable.

Last seat of Bussines Class it does recline but passenger seating behind kept pushing since they did not have space once my seat was reclined

Everything you need to know for your flight from Panama City to Guayaquil

Information on your arrival and departure airports