PTY - GYE

$193 Find Cheap Flights from Panama City to Guayaquil - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to Guayaquil departing on 7/18. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$348
Typical prices: $349-$418
Avianca
Mon 7/27Tue 7/28
PTY - GYE • 1 stop
Cheapest non-stop
$396
Typical prices: $210-$468
Copa Airlines
Thu 8/27Sun 8/30
PTY - GYE • Non-stop
Top airlines
Cheapest • from $348 (round-trip)
Best reviews • 7.6 score
Airline reviews
Airline reviews
+1
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Airline reviews
Airline reviews
+1
Nonstop flights
You can fly direct with Copa Airlines. Average duration is 2h 14m
Direct flights
Direct flights
+1
+1
Direct flights
Direct flights
+1
Avoid delays
Most punctual • 94% on-time
Best time • Fewest delays
Insights
Insights
Insights
Insights
When to travel
Cheapest • 8% price drop
Most popular
Good to know
Good to know
+1
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Good to know
Good to know
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We hope you love your trip to Guayaquil!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Panama City to Guayaquil (PTY-GYE)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama City to Guayaquil that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to Guayaquil

Mon, Jul 27 - Tue, Jul 28
Avianca Logo
10:10 am - 11:30 pm
PTY
-
GYE
13h 20m
1 stop
Avianca Logo
3:30 am - 2:15 pm
GYE
-
PTY
10h 45m
1 stop
$348Avianca
Thu, Jul 30 - Sun, Aug 2
Avianca Logo
10:10 am - 2:35 pm
PTY
-
GYE
4h 25m
1 stop
Avianca Logo
6:50 pm - 12:35 am
GYE
-
PTY
5h 45m
1 stop
$351Avianca
Fri, Sep 11 - Sun, Sep 13
Avianca Logo
4:25 am - 5:35 pm
PTY
-
GYE
13h 10m
1 stop
Avianca Logo
3:30 am - 5:00 pm
GYE
-
PTY
13h 30m
1 stop
$352Avianca
Mon, Jul 27 - Wed, Jul 29
Avianca Logo
4:25 am - 2:35 pm
PTY
-
GYE
10h 10m
1 stop
Avianca Logo
6:50 pm - 9:15 am
GYE
-
PTY
14h 25m
1 stop
$354Avianca
Fri, Sep 11 - Mon, Sep 14
Avianca Logo
4:25 am - 2:35 pm
PTY
-
GYE
10h 10m
1 stop
Avianca Logo
6:50 pm - 12:35 am
GYE
-
PTY
5h 45m
1 stop
$355Avianca
Sat, Aug 1 - Wed, Aug 5
Avianca Logo
4:25 am - 5:35 pm
PTY
-
GYE
13h 10m
1 stop
Avianca Logo
3:45 pm - 12:35 am
GYE
-
PTY
8h 50m
1 stop
$357Avianca
Sat, Aug 1 - Wed, Aug 5
Avianca Logo
4:25 am - 5:35 pm
PTY
-
GYE
13h 10m
1 stop
Avianca Logo
3:45 pm - 12:35 am
GYE
-
PTY
8h 50m
1 stop
$369Avianca
Sat, Oct 31 - Wed, Nov 4
Avianca Logo
2:55 pm - 11:35 pm
PTY
-
GYE
8h 40m
1 stop
Avianca Logo
10:25 am - 4:55 pm
GYE
-
PTY
6h 30m
1 stop
$371Avianca
Sat, Oct 31 - Wed, Nov 4
Avianca Logo
2:55 pm - 11:35 pm
PTY
-
GYE
8h 40m
1 stop
Avianca Logo
10:25 am - 4:55 pm
GYE
-
PTY
6h 30m
1 stop
$372Avianca
Fri, Oct 30 - Wed, Nov 4
Avianca Logo
2:55 am - 9:15 am
PTY
-
GYE
6h 20m
1 stop
Avianca Logo
6:55 pm - 12:40 am
GYE
-
PTY
5h 45m
1 stop
$375Avianca
Booking Insights

KAYAK's insights & trends for Panama City to Guayaquil flights

Get data-powered insights and trends into flights from Panama City to Guayaquil to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Panama City to Guayaquil?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Panama City to Guayaquil departing in July.

What’s the cheapest day of the week to fly from Panama City to Guayaquil?

The average price of all round-trip flights from Panama City to Guayaquil clicked on KAYAK for each day over the last 12 months.

When flying from Panama City to Guayaquil, you should consider leaving on a Sunday and avoid Tuesdays if you are looking for the best rates. For your return to Panama City, you’ll find the best rates on Fridays and the most expensive ones on Sundays.

What is the cheapest month to fly from Panama City to Guayaquil?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Panama City to Guayaquil, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Panama City to Guayaquil is February, where tickets cost $330 (return) on average. On the other hand, the most expensive months are November and June, where the average cost of round-trip tickets is $411 and $396 respectively.

Can I save money by flying with a layover from Panama City to Guayaquil?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $396, prices are generally cheapest when you fly direct.

How far in advance should I book a flight from Panama City to Guayaquil?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Panama City to Guayaquil, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Panama City to Guayaquil, you should book around 1 week before departure. For the absolute cheapest price, our data suggests you should book 21 weeks before departure.

Good to know

Low seasonFebruary
Cheapest flight$193
Best time to beat the crowds with an average 9% drop in price.
Most popular time to fly and prices are also 4% lower on average.
Flight from Panama City to Guayaquil

When to book flights from Panama City to Guayaquil

Are your dates flexible? Find out the best times to travel from Panama City to Guayaquil based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Panama City to Guayaquil

  • What is the cheapest flight from Panama City to Guayaquil?

    In the last 5 days, the lowest price for a flight from Panama City to Guayaquil was $193 for a one-way ticket and $348 for a round-trip.

  • Do I need a passport to fly between Panama City and Guayaquil?

    Yes

  • Which aircraft models fly most regularly from Panama City to Guayaquil?

    The Boeing 737-800 is the aircraft model that flies most regularly on the Panama City to Guayaquil flight route.

  • Which airline alliances offer flights from Panama City to Guayaquil?

    Star Alliance is the only airline alliance operating flights between Panama City and Guayaquil.

  • On which days can I fly direct from Panama City to Guayaquil?

    There are nonstop flights from Panama City to Guayaquil on a daily basis.

  • Which is the best airline for flights from Panama City to Guayaquil, Copa Airlines or Avianca?

    The two airlines most popular with KAYAK users for flights from Panama City to Guayaquil are Copa Airlines and Avianca. With an average price for the route of $362 and an overall rating of 7.6, Copa Airlines is the most popular choice. Avianca is also a great choice for the route, with an average price of $330 and an overall rating of 6.5.

  • How does KAYAK find such low prices on flights from Panama City to Guayaquil?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to Guayaquil.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to Guayaquil?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Guayaquil from Panama City is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to Guayaquil?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Guayaquil with an airline and back to Panama City with another airline. Booking your flights between Panama City and GYE can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to Guayaquil?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Guayaquil from Panama City up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Prefer to fly direct from Panama City to Guayaquil?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Panama City Tocumen Intl to Guayaquil Jose Joaquin de Olmedo.
Find which airlines fly direct from Panama City Tocumen Intl Airport to Guayaquil Jose Joaquin de Olmedo Airport, which days they fly and book direct flights.

Direct departures

Panama City Tocumen Intl to Guayaquil Jose Joaquin de Olmedo

Monday

Copa Airlines

Copa Airlines

Tuesday

Copa Airlines

Copa Airlines

Wednesday

Copa Airlines

Copa Airlines

Thursday

Copa Airlines

Copa Airlines

Friday

Copa Airlines

Copa Airlines

Saturday

Copa Airlines

Copa Airlines

Sunday

Copa Airlines

Copa Airlines

See more direct flights

Direct returns

Guayaquil Jose Joaquin de Olmedo to Panama City Tocumen Intl

Monday

Copa Airlines

Copa Airlines

Tuesday

Copa Airlines

Copa Airlines

Wednesday

Copa Airlines

Copa Airlines

Thursday

Copa Airlines

Copa Airlines

Friday

Copa Airlines

Copa Airlines

Saturday

Copa Airlines

Copa Airlines

Sunday

Copa Airlines

Copa Airlines

See more direct flights

Reviews of the top airlines flying from Panama City to Guayaquil

 
See real verified KAYAK customer reviews for airlines flying from Panama City to Guayaquil. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to Guayaquil? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.6
Copa AirlinesOverall score based on 1559 reviews
6.9Food
7.8Boarding
7.4Comfort
8.1Crew
6.8Entertainment
Airline reviews

stood in line to check in luggage for nearly an hour. very poor service and not excusable

4.0 OkayAnonymous, Jun 2026
PTY - AUS
Read more Copa Airlines reviews

stood in line to check in luggage for nearly an hour. very poor service and not excusable

Orderly boarding, priority for platinum members, courtesy drinks from business class even when we were seating in economy.

Same as the previous flight as far as comfort and food. Entertainment didn’t have a watchable screen so everything would need to be watched on your own device in which they didn’t have a charging port that accommodated my iPhone. Seats were very uncomfortable. Staff was very friendly.

Do not book it’s a scam! They stole $1200 from me

Flight got delayed; had to go through security three times.

Copa staff at PTY and one particular crew member were unhelpful & rude.

A lot things happened in this trip.The fly should be less stress.

Horrible. No TV or any type of entertainment on board. Passwnger listening to/watching stuff on their own phone with no headphones making it noise and uncomfortable for everyone else, little/tiny food portions, old seats, useless wifi (cant access anything). Horrible exlerience especially it was a lomg distance flight with kids.

The flight was good overall. Everything went smoothly, although the landing was a bit rough. Still, it was a pleasant experience

Copa is one of the airlines with the best prices and super good service.

As previously experienced neither check in staff nor cabin crew were friendly or welcoming

The seats were the worst I have ever flown Too narrow, did not recline and the actual seat was hard as a rock. I will tell all travelers to stay away from Avianca flights.

This was my first time flying with you guys and my very last! This was the most horrible experience!!! There was not even tv in the plane! How cheap can this airline be!!! I paid so much for my suitcase!!! I would never fly with this airline again! The crew are very rude!

We waited for one hour to deboard the plane after landing. That could be better

Not even water is offered on the flight. You cannot lean back on the seats and the seats are so narrow you can’t avoid rubbing elbows with the person next to you.

I couldnt recline the seat. Other than that crew was very attentive and helpful. Thsnk you

Charging for WATER on a SIX hour flight in repugnant. Enough said!

Worst in 25 years. A 10 hours flight from Buenos Aires to Costa Rica and no free food! Then the food available for purchase was sold out in 5 minutes. I was travelling with two kids and wasn't ready to keep them happy with chips and cookies for such a long time. Avianca doesn't make sure that minors sit next to an adult so I was forced to pay 65 USD for each seat in a so called premium seat whic is exactly the same as the economy free seats. Never again with Avianca.

Avianca flights to Galapagos and back and well organized and on time.

This is the Spirit of Latino travel. And don’t even get me started on customer service.

Everything you need to know for your flight from Panama City to Guayaquil

Information on your arrival and departure airports