PTY - GYE

$169 Find Cheap Flights from Panama City to Guayaquil

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to Guayaquil departing on 10/12. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Guayaquil

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Guayaquil, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Guayaquil, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Panama City to Guayaquil (PTY-GYE)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama City to Guayaquil that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to Guayaquil

Fri, Oct 31 - Sun, Nov 9
Avianca Logo
2:55 am - 9:15 amPTY-GYE
6h 20m1 stop
Avianca Logo
4:40 am - 2:00 pmGYE-PTY
9h 20m1 stop
$330Avianca
Find Deal
Thu, Oct 30 - Sun, Nov 2
Copa Airlines Logo
9:40 pm - 11:53 pmPTY-GYE
2h 13mnonstop
Copa Airlines Logo
2:35 pm - 4:46 pmGYE-PTY
2h 11mnonstop
$339Copa Airlines
Find Deal
Thu, Sep 18 - Mon, Sep 22
Avianca Logo
10:05 pm - 8:35 amPTY-GYE
10h 30m1 stop
Avianca Logo
2:50 pm - 9:10 pmGYE-PTY
6h 20m1 stop
$341Avianca
Find Deal
Thu, Oct 30 - Sun, Nov 9
Copa Airlines Logo
9:40 pm - 11:53 pmPTY-GYE
2h 13mnonstop
Copa Airlines Logo
4:31 am - 6:39 amGYE-PTY
2h 08mnonstop
$346Copa Airlines
Find Deal
Wed, Oct 29 - Sat, Nov 8
Copa Airlines Logo
9:02 am - 11:16 amPTY-GYE
2h 14mnonstop
Copa Airlines Logo
4:31 am - 6:39 amGYE-PTY
2h 08mnonstop
$348Copa Airlines
Find Deal
Tue, Sep 30 - Thu, Oct 9
Avianca Logo
3:20 am - 11:25 amPTY-GYE
8h 05m2 stops
Avianca Logo
6:25 pm - 12:10 amGYE-PTY
5h 45m1 stop
$350Avianca
Find Deal
Sat, Nov 1 - Sun, Nov 9
Copa Airlines Logo
6:27 pm - 8:43 pmPTY-GYE
2h 16mnonstop
Copa Airlines Logo
4:31 am - 6:39 amGYE-PTY
2h 08mnonstop
$355Copa Airlines
Find Deal
Wed, Nov 5 - Sat, Nov 8
Avianca Logo
2:55 am - 9:15 amPTY-GYE
6h 20m1 stop
Avianca Logo
3:30 am - 8:50 amGYE-PTY
5h 20m1 stop
$357Avianca
Find Deal
Sat, Nov 1 - Fri, Nov 21
Copa Airlines Logo
9:24 pm - 11:41 pmPTY-GYE
2h 17mnonstop
Copa Airlines Logo
4:31 am - 6:39 amGYE-PTY
2h 08mnonstop
$359Copa Airlines
Find Deal
Fri, Oct 24 - Sat, Nov 1
 Logo
3:25 am - 8:35 amPTY-GYE
5h 10m1 stop
 Logo
6:35 pm - 8:41 pmGYE-PTY
2h 06mnonstop

Everything you should know

Top airlines
Avianca
Cheapest • from $330 (round-trip)
Copa Airlines
Best reviews • 7.6 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to book
3 weeks
in advance
Our data shows that travelers who book at least 3 weeks in advance save around 1% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
February
Cheapest • 11% price drop
December
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Cheapest round-trip
$330
Overall average: $325
Avianca
Fri 10/31Sun 11/9
PTY - GYE • 1 stop
Cheapest non-stop
$339
Typical prices: $297-427
Copa Airlines
Thu 10/30Mon 11/10
PTY - GYE • Non-stop
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Guayaquil!
Booking Insights

KAYAK's insights & trends for Panama City to Guayaquil flights

Get data-powered insights and trends into flights from Panama City to Guayaquil to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Panama City to Guayaquil?

The average price of all round-trip flights from Panama City to Guayaquil clicked on KAYAK for each day over the last 12 months.

When flying from Panama City to Guayaquil, you should consider leaving on a Saturday and avoid Thursdays if you are looking for the best rates. For your return to Panama City, you’ll find the best rates on Fridays and the most expensive ones on Sundays.

What is the cheapest month to fly from Panama City to Guayaquil?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Panama City to Guayaquil, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Panama City to Guayaquil is February, where tickets cost $278 (return) on average. On the other hand, the most expensive months are March and April, where the average cost of round-trip tickets is $358 and $331 respectively.

Can I save money by flying with a layover from Panama City to Guayaquil?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 1 stop layover the cheapest option at $347 on average.

How far in advance should I book a flight from Panama City to Guayaquil?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Panama City to Guayaquil, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Panama City to Guayaquil, you should book around 3 weeks before departure, which saves you about 1% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 22 weeks before departure.

Good to know

Low seasonApril
Cheapest flight$169
Best time to beat the crowds but there is an average 5% increase in price.
Most popular time to fly with an average 3% increase in price.
Flight from Panama City to Guayaquil

When to book flights from Panama City to Guayaquil

Are your dates flexible? Find out the best times to travel from Panama City to Guayaquil based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Panama City to Guayaquil

  • What is the cheapest flight from Panama City to Guayaquil?

    In the last 3 days, the lowest price for a flight from Panama City to Guayaquil was $169 for a one-way ticket and $330 for a round-trip.

  • Do I need a passport to fly between Panama City and Guayaquil?

    Yes

  • Which aircraft models fly most regularly from Panama City to Guayaquil?

    The Boeing 737 MAX 9 is the aircraft model that flies most regularly on the Panama City to Guayaquil flight route.

  • Which airline alliances offer flights from Panama City to Guayaquil?

    SkyTeam, and Star Alliance are the airline alliances operating flights between Panama City and Guayaquil, with Star Alliance being the most commonly used for this route.

  • On which days can I fly direct from Panama City to Guayaquil?

    There are nonstop flights from Panama City to Guayaquil on a daily basis.

  • Which is the best airline for flights from Panama City to Guayaquil, Copa Airlines or Avianca?

    The two airlines most popular with KAYAK users for flights from Panama City to Guayaquil are Copa Airlines and Avianca. With an average price for the route of $307 and an overall rating of 7.6, Copa Airlines is the most popular choice. Avianca is also a great choice for the route, with an average price of $330 and an overall rating of 6.7.

  • How does KAYAK find such low prices on flights from Panama City to Guayaquil?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to Guayaquil.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to Guayaquil?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Guayaquil from Panama City is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to Guayaquil?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Guayaquil with an airline and back to Panama City with another airline. Booking your flights between Panama City and GYE can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to Guayaquil?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Guayaquil from Panama City up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Prefer to fly direct from Panama City to Guayaquil?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Panama City Tocumen Intl to Guayaquil Jose Joaquin de Olmedo.
Find which airlines fly direct from Panama City Tocumen Intl Airport to Guayaquil Jose Joaquin de Olmedo Airport, which days they fly and book direct flights.

Direct departures

Panama City Tocumen Intl to Guayaquil Jose Joaquin de Olmedo

Monday

Copa Airlines

Copa Airlines

Tuesday

Copa Airlines

Copa Airlines

Wednesday

Copa Airlines

Copa Airlines

Thursday

Copa Airlines

Copa Airlines

Friday

Copa Airlines

Copa Airlines

Saturday

Copa Airlines

Copa Airlines

Sunday

Copa Airlines

Copa Airlines

See more direct flights

Direct returns

Guayaquil Jose Joaquin de Olmedo to Panama City Tocumen Intl

Monday

Copa Airlines

Copa Airlines

Tuesday

Copa Airlines

Copa Airlines

Wednesday

Copa Airlines

Copa Airlines

Thursday

Copa Airlines

Copa Airlines

Friday

Copa Airlines

Copa Airlines

Saturday

Copa Airlines

Copa Airlines

Sunday

Copa Airlines

Copa Airlines

See more direct flights

Reviews of the top airlines flying from Panama City to Guayaquil

 
See real verified KAYAK customer reviews for airlines flying from Panama City to Guayaquil. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to Guayaquil? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.6
Copa AirlinesOverall score based on 1531 reviews
6.8Entertainment
7.4Comfort
6.8Food
7.8Boarding
8.1Crew
Airline reviews

As always, Copa Airlines is great to fly on. The flights are always on time, the staff are pleasant and helpful and it's always a wonderful flying experience.

10.0 ExcellentNeil, Aug 2025PTY - BGI
Read more Copa Airlines reviews

As always, Copa Airlines is great to fly on. The flights are always on time, the staff are pleasant and helpful and it's always a wonderful flying experience.

We had a great flight just wished they had a tv so we can see a movie that would of made my trip excellent.

horrible service, food was an embarrassment, no charging for cellphones, stay away

the food served was an embarrassment. No connection for charging the cellphone... What a crappy airline.

Great experience with a crew always thinking in the passenger

Did upgrade, travel in business it was great (more room I could sleep)

Had to go through security at the gate again. Had to take off shoes and go through the whole thing again even though we have global entry. They asked us to check in items bought at duty free during our layover and since we checked our luggage at the original departure airport, they forced us to check in a small backpack. None of this ever happened with other airlines. In addition, no vegetarian food option and no snacks during a 7 hr flight. Luggage limits are unusually small. This is unacceptable. Will NEVER fly Copa again and will tell friends and family to avoid this airline.

We paid extra with copa for seats near one another The plane was changed and we lost our seats We were all Separated. We have not received a refund for our seats despite emailing and calling.

We had a five hour layover in the way home from Colombia. I read the "bout your flight" email carefully before we checked bags. We had to go through security right at the gate. Almost lost our ground coffee because that airport only allows 16 ounce of coffee and we had 18. I've been to 48 countries and never heard of a coffee restriction. I can't follow a rule I don't know about. I requested they bring our coffee to our checked luggage. Instead tey gate checked our bag for free. Back to planning transfers in Dallas I guess

It was ok. However, the food was quite poor since I don't eat pasta.

Usb plugs for charging your phone does not work in every flight. uncomfortable chairs even in higher categories.

Luggage lost and nowhere to be found, no response from either airline regarding my bag

Avianca is not what it used to be. So disappointing

It was horrible. My experience with Avianca. I didn’t know it was Pakistan international Airlines but anyway, whatever it is it is bad horrible you guys need to upgrade everything in those planes. And you guys charge $130 for a carry-on did they wanna let me in with my carry-on that I travel everywhere with the luggage you guys are such a dog thank you

The incoming plane was late and no information was shared. They even announced we would board in 10 muntes 40 minutes prior to the plane arriving, and the website said until takeoff that we had taken off an hour earlier

Boarding was excessively slow. They do it by groups in a way that it doesn’t make sense. After business class , ppl that need assistance and any other priority group they should have ppl board from the back to the front. First rows 20+. Then 15+. Then 10, etc. having ppl sitting in the back board last makes no sense. The libe backame long as soon as ppl on rows 10 or so where told to board. The line went all the way up the ramp and tunnel for 25 mins.

The chicken that was served in business class was cold!

Late departure. When the flight arrived in Medellin the plane sat at the gate for 20 minutes waiting for a bus for us to get off the plane.

Purchased a business class ticket and got a economy seat with center seat blocked they call it business. 3100usd ticket on a flight where economy costs 500usd The biggest scam insult have had on a regular airline. Avianca should be in the low cost category and kicked out of Star Alliance. I want the difference to be credited. Ets see what Avianca does. No reply so far. Avianca = low cost airline. Beware

Business class seats did not lie flat. There was only powdered milk for your coffee....in Business Class!! Food was good.

Everything you need to know for your flight from Panama City to Guayaquil

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