Find Cheap Flights from Raleigh-Durham to South America

Depart
Return
1 adult
Adults
18-64
Seniors
65+
Youths
12-17
Children
2-11
Seat Infants
under 2
Lap Infants
under 2
The price shown for each flight will be the average for all passengers including any infants.
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Dates flexible? Here are the best fares found in the past 48 hours...

Book cheap flights from Raleigh-Durham to South America

(Round-trip)
Depart: Sun Jan 21 2018 Return: Thu Jan 25 2018 Trip spans 5 days
American Airlines
American Airlines
RDU
CTG
18h 07m
2 stops
CTG
RDU
21h 35m
2 stops
Depart: Sat Oct 14 2017 Return: Fri Oct 20 2017 Trip spans 7 days
JetBlue
JetBlue
RDU
MDE
11h 20m
1 stop
MDE
RDU
8h 54m
1 stop
Depart: Sun Oct 8 2017 Return: Mon Oct 9 2017 Trip spans 2 days
Multiple Airlines
Multiple Airlines
RDU
MDE
20h 04m
1 stop
MDE
RDU
8h 54m
1 stop
Depart: Fri Mar 2 2018 Return: Thu Mar 22 2018 Trip spans 20 days
LATAM Airlines
LATAM Airlines
RDU
BOG
8h 48m
1 stop
BOG
RDU
15h 06m
2 stops
Depart: Tue Oct 17 2017 Return: Fri Nov 17 2017 Trip spans 32 days
Copa Airlines
Copa Airlines
RDU
MDE
12h 26m
2 stops
MDE
RDU
13h 52m
2 stops
Depart: Wed Jan 24 2018 Return: Sun Jan 28 2018 Trip spans 5 days
American Airlines
American Airlines
RDU
CTG
6h 32m
1 stop
CTG
RDU
21h 14m
1 stop
Depart: Wed Jan 17 2018 Return: Sun Jan 21 2018 Trip spans 5 days
American Airlines
American Airlines
RDU
CTG
21h 37m
2 stops
CTG
RDU
21h 14m
1 stop
Depart: Tue Feb 13 2018 Return: Fri Mar 23 2018 Trip spans 38 days
LATAM Airlines
LATAM Airlines
RDU
MDE
8h 50m
1 stop
MDE
RDU
8h 12m
1 stop
Depart: Wed Sep 27 2017 Return: Wed Oct 11 2017 Trip spans 15 days
Multiple Airlines
Multiple Airlines
RDU
BOG
11h 05m
1 stop
BOG
RDU
21h 23m
1 stop
Depart: Tue Oct 24 2017 Return: Thu Nov 2 2017 Trip spans 10 days
American Airlines
American Airlines
RDU
LIM
11h 07m
1 stop
LIM
RDU
16h 08m
1 stop
Depart: Wed Oct 11 2017 Return: Fri Oct 20 2017 Trip spans 10 days
JetBlue
JetBlue
RDU
UIO
13h 50m
1 stop
UIO
RDU
9h 35m
1 stop
Depart: Wed Feb 14 2018 Return: Fri Mar 23 2018 Trip spans 37 days
LATAM Airlines
LATAM Airlines
RDU
MDE
8h 50m
1 stop
MDE
RDU
8h 12m
1 stop
Depart: Wed Oct 18 2017 Return: Fri Nov 17 2017 Trip spans 31 days
Copa Airlines
Copa Airlines
RDU
MDE
15h 06m
2 stops
MDE
RDU
24h 08m
2 stops
Depart: Tue Oct 24 2017 Return: Thu Nov 2 2017 Trip spans 10 days
American Airlines
American Airlines
RDU
LIM
11h 07m
1 stop
LIM
RDU
16h 08m
1 stop
Depart: Fri Oct 13 2017 Return: Fri Oct 20 2017 Trip spans 8 days
JetBlue
JetBlue
RDU
UIO
13h 50m
1 stop
UIO
RDU
9h 35m
1 stop
Depart: Thu Feb 15 2018 Return: Fri Mar 23 2018 Trip spans 36 days
LATAM Airlines
LATAM Airlines
RDU
MDE
8h 50m
1 stop
MDE
RDU
8h 12m
1 stop
Depart: Thu Oct 26 2017 Return: Mon Oct 30 2017 Trip spans 5 days
Multiple Airlines
Multiple Airlines
RDU
BAQ
22h 28m
2 stops
BAQ
RDU
27h 26m
2 stops
Depart: Fri Oct 20 2017 Return: Fri Nov 17 2017 Trip spans 29 days
Copa Airlines
Copa Airlines
RDU
MDE
12h 26m
2 stops
MDE
RDU
24h 08m
2 stops
Depart: Wed Oct 25 2017 Return: Thu Nov 2 2017 Trip spans 9 days
American Airlines
American Airlines
RDU
LIM
14h 19m
1 stop
LIM
RDU
9h 59m
1 stop
Depart: Fri Feb 16 2018 Return: Fri Mar 23 2018 Trip spans 35 days
LATAM Airlines
LATAM Airlines
RDU
MDE
8h 50m
1 stop
MDE
RDU
8h 12m
1 stop
* Prices are per person and are for e–tickets and include all taxes & fees in USD.

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At KAYAK we don’t set the prices, so it’s not possible for us to guarantee what other companies are selling.

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Our service lets you quickly and easily compare results from hundreds of travel sites at once. In this sense, KAYAK is a search engine and we can't guarantee prices we find.

Why aren’t prices accurate 100% of the time?
Prices on airline seats, hotel rooms and car rentals can change frequently. Several people may also be trying to buy the same travel option simultaneously. As a result, you may find, on occasion, that certain prices are no longer available.

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Airports
Origin

Raleigh
$399
Destination

Lima
$461
Medellin
$457
Cartagena
$399
Quito
$558
Bogotá
$508
Barranquilla
$583